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Evaluation of animal biosafety webinar series for professionals working in animal facilities across Pakistan during the COVID-19 pandemic

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Journal of Biosafety and Biosecurity 2022年第1期4卷 12-16页

作者： Saima Mohsin shamsul arfin qasmi Samreen Sarwar Dr.Panjwani Center for Molecular Medicine and Drug Research University of KarachiPakistan Bahawalpur Medical&Dental College Pakistan Health security Partners USA

Experimental research with animals can help the prevention,cure,and alleviation of human *** research facilities are critical for scientific advancement,but they can also pose a higher risk than other biomedical ***,allergic reactions,bites,cuts,and scratches by animals are all substantial concerns that can occur in animal ***,human error and unexpected animal behavior pose a risk not just to humans,but also to the environment and the animals *** majority of biosafety and biosecurity training programs focus on clinical and biomedical laboratories dealing with human safety factors,with little emphasis on animal *** current virtual training was designed to improve biosafety and biosecurity capabilities of animal laboratory personnel,researchers,and veterinarians from different regions of *** results revealed that understanding was improved regarding triggers for risk assessment in addition to annual and regular reviews(56%to 69%),biosecurity(21%to 50%),decontamination(17%to 35%),safe handling of sharps(21%to 35%),Dual Use Research of Concern(DURC)(17%to 40%),Personal Protective Equipment(PPE)usage by waste handlers(60.9%to 75%),waste management(56%to 85%),animal biosafety levels(40.57%to 45%),and good microbiological practices and procedures(17%to 35%).To bring human and animal laboratories up to the same level in terms of biosafety and biosecurity,it is critical to focus on areas that have been overlooked in the *** programs focusing on animal biosafety should be conducted more frequently to strengthen bio risk management systems in animal research facilities.

关键词： Animal biosafety Virtual training Animal research facilities Biorisk management

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Mobile biosafety level (BSL) 2 laboratories deployment: Strengthening the diagnostic facilities in Pakistan with emerging public health challenges and the way forward

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Journal of Biosafety and Biosecurity 2023年第2期5卷 79-83页

作者： shamsul arfin qasmi Aamer Ikram Muhammad Tariq Muhammad Tahir Khadim Nabeel Ahmed Maqbool Principal/HOD Pathology Bahawalpur Medical&Dental CollegeBahawalpur Pakistan Executive Director National Institute of Health IslamabadPakistan Country Director Chemonics International IslamabadPakistan Principal Fazaia Medical College and Dean Faculty Health Sciences Air University IslamabadPakistan GHSC.PSM Pakistan

Availability of mobile laboratories can facilitate rapid on-spot detection of pathogens,monitor its presence in certain populations and inform health authorities to take immediate remedial *** available biosafety and biosecurity guidelines and policies may not completely articulate the increased demand to manage mobile units in infectious disease outbreaks in remote parts of the country for rapid diagnosis,and also allows research and epidemiological study take place *** main objective of this study is to evaluate the current limitations and develop and implement biosafety and biosecurity guidelines as well as the protocols for operations,security,and response plan of mobile biosafety level 2 laboratories and their *** in view the sensitivity of it,a comprehensive plan was developed to address it in view of Global Health Security *** and biosecurity protocols were developed including Risk Assessment Tool(RAT)fitting the needs and strengthen the diagnostic and epidemiological capacity in the field covering remote parts of country to fill the gaps observed during the COVID-19 *** the biosafety and biosecurity best practices guidelines and biosecurity policy and regulations are directed mostly towards static laboratories.A biosafety and biosecurity manual developed to adopt and meet the requirements for MBSL *** acute health infectious threats including the COVID-19 outbreak and other epidemics,rapid diagnosis can curb and mitigate the problem before it gets out of its boundaries creating significant health risks for the public and *** deployment of mobile laboratories will certainly help in curbing these catastrophes.

关键词： Biosafety manual Biorisk Management Risk Assessment Mobile BSL 2 Laboratories(MBSL2Laboratories) Outbreak Response

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Capacity building for the identification,mitigation,and communication of DURC in Pakistan:A cross-sectional study

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Journal of Biosafety and Biosecurity 2021年第2期3卷 141-146页

作者： shamsul arfin qasmi Samreen Sarwar Muhammad Azheruddin Department of Pathology Fazaia Ruth Pfau Medical CollegeKarachiSindhPakistan Technical Advisor Health Security PartnersLahorePakistan and Department of MicrobiologyUniversity of Health Sciences LahorePakistan Department of Community Medicine Fazaia Ruth Pfau Medical CollegeKarachiSindhPakistan

The increasing threat posed by state and nonstate actors seeking to misuse scientific and technological developments means it is more important than ever to ensure the responsible conduct of life sciences research,biosecurity research,and dual-use research of concern(DURC).Pakistan has a rapidly growing research environment and,being a signatory to the Biological Toxins and Weapons Convention,is committed to raising DURC awareness among its *** this end,a series of five workshops were conducted in Pakistan between July 2018 and January 2020 with the support of the United States organization Health Security *** workshops targeted universities offering postgraduate programs in life and medical *** purpose of the workshops was to enable participants to understand the concept of DURC,review their own research,determine if any of their experiments may be DURC,identify potential risks while conducting the research,and develop protocols to mitigate DURC threats.A pre-and post-workshop questionnaire evaluated the knowledge of the *** of both the course and facilitators were obtained at each workshop.

关键词： Dual-use research Knowledge Pakistan Training

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Review of biological waste management in research,biomedical,and veterinary laboratories in Karachi,Pakistan

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Journal of Biosafety and Biosecurity 2019年第2期1卷 100-104页

作者： shamsul arfin qasmi Bilal A.Khan Dept.of Pathology Karachi Institute of Medical SciencesKarachiPakistan DUHS KarachiPakistan

*** Healthcare facilities that include laboratories provide services to patients and help in safeguarding public *** also generate a large amount of waste,which can create serious health problems for the public if it is not treated and disposed of as per institutional/local and international *** facilities produce diverse wastes,which include hazardous infectious waste.

关键词： waste services facilities

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Survey on proper and safe use of biological safety cabinets (BSCs) in research, bio-medical and animal laboratories in Karachi, Pakistan a cross sectional study

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Journal of Biosafety and Biosecurity 2020年第2期2卷 77-80页

作者： shamsul arfin qasmi Sarmad Pirzada Afsheen Ghani Saima Mohsin Department of Pathology/Microbiology Fazaia Ruth Pfau Medical College Air UniversityFazaia Ruth Pfau Medical CollegeFaisal Cantonment BoardKarachiPakistan Department of Medicine Dr Ruth Pfau Civil Hospital KarachiPakistan Infectious Disease Laboratory KarachiKarachi CityPakistan Department of Molecular Medicine International Center for Chemical and Biological Sciences(ICCBS)Pakistan

Introduction:Past incidences have been recorded relating to mishandling of hazardous material either due to insufficient knowledge or inappropriate equipment resulting in the indirect transfer of infectious *** is necessary to identify gaps that inhibit proper protection of healthcare professionals from being inadvertently exposed to biological ***:A cross sectional study was conducted at multiple laboratories across Karachi,Pakistan from January to August *** questionnaire was used to record data about types and usage of Biological Safety Cabinets(BSCs),along with policies and practices adapted for its ***:A total of 30 laboratories were visited which included Clinical/Biomedical,University hospital,R&D and animal *** these 60%always used BSCs,30%periodically used BSCs while 10%did not have any *** these facilities 63.6%had BSC class II-A2,39.9%had BSC class II-B2,4.5%had BSC class III and only 0.9%had BSC class I *** protocols for field certification of BSCs were ***:Establishment of biosafety training sessions,implementation and development of protocol for field certification for proper and safe use of BSCs on a local basis accompanied by continuous monitoring is required,for creating a safe environment for all laboratory staff.

关键词： Biosafety Public health Biohazard containment Equipment and supplies

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Assessment and impact of a biosecurity course in raising the awareness of students at the Jinnah post graduate Medical Center,Pakistan

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Journal of Biosafety and Biosecurity 2019年第2期1卷 93-97页

作者： shamsul arfin qasmi Mehwish Zafar Sarmad Pirzada Kauser Abbas Saldera Aftab Turabi Fazaia Ruth Pfau Medical College Pakistan Karachi Institute of Medical Sciences Pakistan Dow University of Health Sciences Pakistan BMSI JPMC Pakistan

Introduction:Pakistan Biological Safety Association(PBSA)is a not for profit,nongovernmental,professional organization established in 2008 and is striving to promote and implement Bio risk management in *** accelerated its program for strategic training of the national life scientists from 2013 and is still working on that mandate with the help of Fogarty International Center(FIC)&National Institute of Health USA and other international organizations working on this Global Health Security Initiative and subsequently Agenda(GHSA)Aims&Objectives:This biosafety training program was developed for capacity building of *** PhD graduates the future laboratory users of Basic Medical Sciences Institute(BMSI),Jinnah Post Graduate Medical Center which is the largest tertiary care hospital in Karachi,Pakistan involved in Research&Development(R&D)in medical ***&Methods:This Pre post study was carried at Basic Medical Sciences Institute(JPMC),during the period of October 2018 to January 2019.A total of 48(16 PhD.32 ***.)Grads students participated in the following *** training program is administered through,custom made 4-month course having 16 contact hours also 4 hours of practical *** was evaluated using written *** pre and post-training test was conducted after each *** test comprised of 15 multiple choice questions(MCQs)pre and post session making it 30 MCQs in total for each session.A final assessment consisting 30 MCQs conducted at the end of ***:There was vast difference observed in the post assessment results as compared to the pre assessment *** the end of the course final assessment was carried out which gave an overall impression of vast change(83.3%)in awareness regarding bio risk management among the graduate students,which reflected the efficacy of this *** ensure the validity of results and the intention to improvise the quality of course in future,feedback regardi

关键词： Antimicrobial resistance Extended spectrum beta lactamase(ESBL) Urinary tract infections(UTIs) Gram negative bacteria(GNB)

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