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Quality of life and oral potentially malignant disorders: Critical appraisal and prospects

World Journal of Clinical Oncology 2018年第4期9卷 56-59页

作者： shailesh m gondivkar Rahul R Bhowate Amol R Gadbail Sachin C Sarode Shankargouda Patil Department of Oral medicine and Radiology Government Dental College and Hospital Department of Oral medicine and Radiology Sharad Pawar Dental College and Hospital Department of Dentistry Indira Gandhi Government Medical College and Hospital Department of Oral Pathology and microbiology Dr. D.Y. Patil Dental College and Hospital Department of maxillofacial Surgery and Diagnostic Sciences Division of Oral Pathology College of Dentistry Jazan University

Quality of life(QoL) is a vital and often required health outcome measure that is relevant to patient care. A healthy oral cavity enables person to perform daily activities without any limitations. However, any disturbance may result in impaired QoL. The oral health-remains an essential element of people's health and well-being. In recent years, the tradition of clinical practice and research has been changed by incorporating QoL assessment, as it helps in assessment of patients' needs and monitoring treatment responses. Oral potentially malignant disorders(OPmDs) are a group of chronic disorders including oral leukoplakia(OL), oral lichen planus and oral submucous fibrosis(OSF). It is evident that patients with OPmDs experience significant health-related symptoms, functional limitations and psycho-social impairment, compromising their Qo L. moreover, the worsening of Qo L has been associated with advanced stages of OPmDs. Despite of increasing number of OPmD cases in recent decades, limited literature is available regarding QoL in this population. Although, there is higher prevalence of habit-related OPmDs, particularly OSF and OL in Southern Asian countries, only a few studies have been performed in these populations. moreover, these studies administered generic Qo L instruments, which offer less sensitivity to clinical changes. However, condition-specific instruments are more sensitive and allows better measurement of QoL. As the impacts of different conditions on OHRQoL may vary, the development and validation of a QoL instrument specific to each clinical entity of OPmDs is currently needed.

关键词： Quality of life Oral potentially malignant disorders Oral submucous fibrosis Oral lichen planus Oral leukoplakia

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Rescue from complications after pancreaticoduodenectomies at a low-volume Caribbean center:Value of tailored peri-pancreatectomy protocols

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World Journal of Gastrointestinal Surgery 2024年第3期16卷 681-688页

作者： Shamir O Cawich Elijah Dixon Parul J Shukla shailesh V Shrikhande Rahul R Deshpande Fawwaz mohammed Neil W Pearce Wesley Francis Shaneeta Johnson Johann Bujhawan Department of Surgery University of the West IndiesSt Augustine 000000Trinidad and Tobago Department of Surgery Faculty of MedicineUniversity of CalgaryCalgaryAlberta T2N2T9Canada Department of Surgery Weill Cornell Medical CollegeNew YorkNY 10065United States Department of Surgical Oncology Tata Memorial CenterHomi Bhabha National UniversityMumbai 400012India Department of Surgery Manchester Royal InfirmaryManchester M139WLUnited Kingdom University Surgical Unit Southampton General HospitalSouthampton SO166YDUnited Kingdom Department of Surgery University of the West IndiesNassau N-1184Bahamas Department of Surgery Morehouse School of MedicineAtlantaGA 30310United States Department of Surgery General Hospital in Port of SpainPort of Spain 000000Trinidad and Tobago

BACKGROUND Pancreaticoduodenectomy(PD)is a technically complex operation,with a re-latively high risk for *** ability to rescue patients from post-PD complications is as a recognized quality *** protocols were instituted at our low volume facility in the year *** To document the rate of rescue from post-PD complications with tailored protocols in place as a measure of *** A retrospective audit was performed to collect data from patients who experienced major post-PD complications at a low volume pancreatic surgery unit in Trinidad and Tobago between January 1,2013 and June 30,***-dardized definitions from the International Study Group of Pancreatic Surgery were used to define post-PD complications,and the modified Clavien-Dindo classification was used to classify post-PD *** Over the study period,113 patients at a mean age of 57.5 years(standard deviation[SD]±9.23;range:30-90;median:56)underwent PDs at this *** complications were recorded in 33(29.2%)patients at a mean age of 53.8 years(SD:±7.9).Twenty-nine(87.9%)patients who experienced major morbidity were salvaged after aggre-ssive treatment of their ***(3.5%)died from bleeding pseudoaneurysm(1),septic shock secondary to a bile leak(1),anastomotic leak(1),and myocardial infarction(1).There was a significantly greater salvage rate in patients with American Society of Anesthesiologists scores≤2(93.3%vs 25%;P=0.0024).CONCLUSION This paper adds to the growing body of evidence that volume alone should not be used as a marker of quality for patients requiring *** low volumes at our facility,we demonstrated that 87.9%of patients were rescued from major *** attributed this to several factors including development of rescue protocols,the competence of the pancreatic surgery teams and continuous,and adaptive learning by the entire institution,cul-minating in the development of tailored peri-pancreatectomy protoc

关键词： Pancreas Complication Rescue Failure morbidity mortality Pancreaticoduodenectomy

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A novel method of water remediation of organic pollutants and industrial wastes by solution- route processed CZTS nanocrystals

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Journal of materiomics 2021年第5期7卷 904-919页

作者： Pooja Semalti Vikash Sharma shailesh Narain Sharma CSIR-National Physical Laboratory(NPL) Dr.K.S.Krishnan RoadNew Delhi110012India Academy of Scientific and Innovative Research(AcSIR) Council of Scientific&Industrial Research(CSIR)-Human Resource Development Centre(CSIRHRDC)CampusGhaziabadUttar Pradesh201002India

CZTS(Cu_(2)ZnSnS_(4)),a P-type semiconductor with a direct bandgap(1.2-1.7eV),earth-abundant,non-toxic,and has a large absorption coefficient makes it extremely useful in optoelectronics and light-harvesting *** this work,CZTS is prepared by an ingenious,cost-effective colloidal route using the‘hotinjection’method with the usage of different *** XRD and Raman spectroscopy shows the single-phase highly crystalline CZTS nanoparticles with kesterite *** TEm results show that the size of CZTS nanoparticles is about 2-5 nm and monodispersity is confirmed by DLS(Dynamic Light Scattering).FTIR confirms the presence of different ligands used in CZTS *** Uv-vis absorption shows the direct bandgap of *** contact angle study shows the hydrophobic nature of as-synthesized CZTS nanoparticles which were further ligand exchanged with L-cysteine hydrochloride to make it hydrophilic to study the photocatalytic degradation activity of organic pollutants and industrial waste in the *** photocatalysis experiments were performed under two conditions:(i)under bare sunlight(Intensity~900 W/m^(2))(ii)focussing the sample under the sunlight via converging lens(1800 W/m^(2)).The photocatalytic efficiencies were then compared and the best photocatalytic efficiency achieved under sunlight was 98.4%for organic pollutants and 75%for industrial waste via converging lens while the corresponding efficiencies with bare sunlight were 98.1% and 73% *** the best of the author’s knowledge,a rapid and highly efficient photocatalysis of CZTS NPs employing a converging lens for water-remediation without the usage of noble&transition-metals has been reported for the first time.

关键词： Photocatalysis Copper zinc tin sulfide(CZTS) Converging lens Industrial waste Hot injection Organic pollutants Nanoparticles TOP TOPO

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Potential groundwater recharge zones within New Zealand

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Geoscience Frontiers 2019年第3期10卷 1065-1072页

作者： shailesh Kumar Singh malte Zeddies Ude Shankar George A.Griffiths National Institute of Water and Atmospheric Research

Water resources in New Zealand are not evenly distributed across the country which makes it difficult to adequately allocate the use of water resources in every basin. Groundwater is a fundamental water resource in New Zealand for agricultural, industrial and domestic use. Detailed knowledge regarding groundwater recharge potential is a pre-requisite for sustainable groundwater management, including the assessment of its vulnerability to contamination by pollutants. In this study, a comprehensive GIS approach was used to map the potential groundwater recharge zones across New Zealand. National data sets of lithology, slope, aspect, land use, soil drainage and drainage density were converted to raster data sets with a spatial resolution of 500 m x 500 m and superimposed to derive groundwater potential zones. The resultant maps demonstrate that the potential is low in urban and mountainous areas, such as the Southern Alps, whereas the highest potential can be found in regions with large lakes and in the lower elevation plains areas, where Quaternary sediments prevail. The resulting maps can be used to identify areas of high nutrient leaching in zones where high groundwater recharge potential exists.

关键词： GIS Potential groundwater recharge map New Zealand

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A database of modeled gridded dry deposition velocities for 45 gaseous species and three particle size ranges across North America

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Journal of Environmental Sciences 2023年第5期127卷 264-272页

作者： Leiming Zhang Zhuanshi He Zhiyong Wu Anne marie macdonald Jeffrey R.Brook shailesh Kharol Air Quality Research Division Science and Technology BranchEnvironment and Climate Change CanadaTorontoON M3H 5T4Canada Department of Chemical Engineering and Applied Chemistry University of TorontoTorontoON M5S 2E4Canada

The dry deposition process refers to the flux loss of an atmospheric pollutant due to uptake of the pollutant by the earth’s *** deposition flux of a chemical species is typically calculated as the product of its surface-layer concentration and its dry deposition velocity(V_(d)).Field measurement based V_(d) data are very scarce or do not exist for many chemical species considered in chemistry transport *** the present study,gaseous and particulate dry deposition schemes were applied to generate a database of hourly V_(d) for 45 gaseous species and three particle size ranges for two years(2016–2017)at a 15 kmby 15 km horizontal resolution across North *** V_(d) of the 45 gaseous species ranged fromm/sec across the whole domain,with chemical species-dependentmedian(mean)values being in the range of 0.018–1.37 cm/sec(0.05–1.43 cm/sec).The spatial distributions of the two-year average V_(d) showed values higher than 1–3 cm/sec for those soluble and reactive species over certain land *** species have the highest V_(d) over water surfaces,while insoluble but reactive species have the highest V_(d) over *** V_(d) of Pm_(2.5) across the whole domain ranged from 0.039 to 0.75 cm/sec with median(mean)value of 0.18(0.20)cm s^(−1),while the mean V_(d) for Pm_(2.5)–10 is twice that of Pm_(2.5).Uncertainties in the modeled V_(d) are typically on the order of a factor of 2.0 or larger,which needs to be considered when applying the dataset in other studies.

关键词： Air quality modeling Atmospheric pollutant Atmospheric deposition Dry deposition velocity Spatiotemporal distribution

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