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Lower Lid Entropion Secondary to Missed Intraorbital Foreign Body in a Child

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Open Journal of Ophthalmology 2016年第4期6卷 198-204页

作者： Othman Khairuddin abdul rashid Suraida Li Min Evelyn Tai Hussein Adil Ahmad Tajudin Liza-Sharmini Ibrahim Mohtar Department of Ophthalmology School of Medical Sciences Universiti Sains Malaysia Health Campus Kubang Kerian Malaysia Hospital Universiti Sains Malaysia Kubang Kerian Malaysia

Background: Intraorbital foreign bodies can result in various complications if not appropriately managed. Aim: To report a case of lower lid entropion secondary to a missed intraorbital foreign body. Case Presentation: A 7-year-old boy presented with inward turning of the left lower lid for three days prior to admission. A week before, the child was in the garden when part of the roof of their home suddenly broke off, with pieces of the debris falling near him. He complained of left eye irritation, but a visit to a general practitioner found no eye abnormalities. Three days after that, the mother sought an ophthalmology opinion as she noticed inversion of the left lower lid. On examination, visual acuity in both eyes was 6/6. There was left lower lid entropion, and a deeply embedded foreign body seen in the lower lid. No other eye abnormalities noted. Computed tomography scan of the orbits revealed a welldefined foreign object in the lower orbit, fracturing the antero-superior wall of the left maxillary sinus. The left eye foreign body was removed uneventfully via a transconjunctival approach. Conclusion: A thorough examination is mandatory in any case of ocular trauma especially in young children, who are usually unable to provide a clear history of the injury.

关键词： Eye Eye Injuries Eye Foreign Bodies Child Entropion

Optimization of Mycelial Biomass Production in Submerged Culture Fermentation of <i>Pleurotus flabellatus</i>Using Response Surface Methodology

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Advances in Bioscience and Biotechnology 2015年第6期6卷 419-426页

作者： Shaiful Azuar Mohamad Mat Rasol Awang Rosnani abdul rashid Liew Siew Ling Fauzi Daud Aidil abdul Hamid Rahayu Ahmad Wan Mohtar Wan Yusoff Agrotechnology and Biosciences Division Malaysian Nuclear Agency Bangi Malaysia Faculty of Science and Technology Universiti Kebangsaan Malaysia Bangi Malaysia

The factors selected to optimize the productivity of Pleurotus flabellatus biomass in 250ml working volume Erlenmeyer flask were agitation rate, initial pH value and incubation temperature. The central composite design was applied to study the significant factors and the interactions between the chosen factors, if present. The Design Expert software generated 20 runs. The optimized conditions obtained were as follows: the agitation rate of 129.8 rpm, incubation temperature at 27.8°C, and initial pH of 6.06. The optimized conditions tripled the productivity at the range of 980 - 1040 mg/litre/day compared to the initial rate productivity at 310 mg/litre/day. From the quadratic equation,the agitation rate, temperature and the interaction between agitation rate and temperature were found to be significant (p < 0.05). At optimum conditions, the experimental data supported the theoretical estimate.

关键词： Submerged Culture Fermentation Response Surface Methodology Mushroom Production

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单个纳米孔的宽带光子自旋‐霍尔效应

光电工程 2017年第6期44卷 568-568,659页

作者： Huangping Yan Mohamed Raiz B abdul rashid Si Ying Khew Fengping Li Minghui Hong

光子自旋-霍尔效应（SHEL）指不同自旋态（圆偏振）的光子在一定条件下发生分裂的现象,在光学测量、成像、传感等领域具有重要应用前景。然而,一般条件下SHEL比较微弱,虽然通过谐振能增强分裂强度,但响应带宽受限。近期,微细加工光学技... 详细信息

光子自旋-霍尔效应（SHEL）指不同自旋态（圆偏振）的光子在一定条件下发生分裂的现象,在光学测量、成像、传感等领域具有重要应用前景。然而,一般条件下SHEL比较微弱,虽然通过谐振能增强分裂强度,但响应带宽受限。近期,微细加工光学技术国家重点实验室突破了上述难题,通过理论和实验证明尺度仅为2mm的单个悬链线结构即可产生宽带SHEL,相关文章近期发表于《Light：Science＆Applications》。

关键词：霍尔效应自旋态光子宽带国家重点实验室纳米孔微细加工光学技术光学测量

Production of Endopolysaccharides from Malaysia’s Local Mushrooms in Air-Lift Bioreactor

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Advances in Bioscience and Biotechnology 2015年第7期6卷 456-462页

作者： Shaiful Azuar Mohamad Mat Rasol Awang Rusli Ibrahim Choong Yew Keong Mohd Yusof Hamzah Rosnani abdul rashid Sobri Hussein Khairuddin abdul Rahim Fauzi Daud Aidil abdul Hamid Wan Mohtar Wan Yusoff Agrotechnology and Biosciences Division Malaysian Nuclear Agency Bangi Malaysia Herbal Medicine Research Centre Institute For Medical Research Kuala Lumpur Malaysia Faculty of Science and Technology Universiti Kebangsaan Malaysia Bangi Malaysia

Four local mushroom species, viz. Auricularis polytricha, Lentinus edodes, Agrocybe sp and Pleurotus flabellatus were grown under submerged culture and screened for endopolysaccharides. The fermentation was done in 250 ml working volume Erlenmeyer flask and the fermentation curves for all species were established. Pleurotus flabellatus has the highest rate of biomass production at the rate of 0.180 g/L/day, at 10 days hence chosen for further investigation. Two additional media, viz. Mushroom Complete Media (MCM) and Yeast Malt (YM) were selected to be compared with potato extract(PE) media used initially. MCM media produced the highest biomass productivity at the rate of 0.311 g/L/day. Pleurotus flabellatus biomass was extracted using modified Mizuno method and the endopolysaccharide obtained was tested for β-glucan. The yield of β-glucan was 7.70 ± 1.11 g/100g. The polysaccharides were purified using column chromatography to yield four fractions. The fourth fraction F4, gave the highest molecular weight at 3.058 × 106 Dalton (11.8%) and 1.282 × 104 Dalton (88.2%). The mushroom, P. flabbelatus was cultured using air-lift bioreactor, and the highest productivity was obtained at air-flowrate 2 L/min, yielding 2.25 g/L/day. The yield of biomass against substrate used (glucose consumption) Yb/s was 0.78 g/g.

关键词： Submerged Culture Fermentation Mushroom β-Glucan Column Chromatography Molecular Weight

Financial Vulnerability, Capital Flow Reversals, and Divergence Macro-Prudential Policies Posing Challenges to the ASEAN Banking Integration Framework （ABIF）

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Journal of Modern Accounting and Auditing 2016年第5期12卷 250-267页

作者： Mohd Yaziz Mohd Isa Yap Voon Choong David Yong Gunn Fie Md. Zabid Haji abdul rashid Universiti Tun abdul Razak Kuala Lumpur Malaysia Multimedia University Selangor Malaysia

Against the prevailing background of an unusual capital flow reversal which is posing immense challenges to the integration of the region＇s banking sector, this study measures macro-prudential instruments affecting the implementation of an integrated financial service industry. This study is important at times when domestic and country-based financial policies are directed at competing goals. The interaction of macro-prudential policies with other policies, in particular monetary policies and micro-prudential policies is crucial to address systemic risk involved. There is growing recognition that prudential policies tools interact and coordinate with one another. To utilize multiple instruments seems to provide a greater assurance of effectiveness by tackling risk from various angles. As such, this study also assesses the interactions of the policies. The study also proposes a baseline model to capture systemic risk due to liquidity risk and risk because of currency devaluation.

关键词： capital flow reversals macro-prudential policies ASEAN Banking Integration Framework (ABIF)

Estimation of HCV viral load and liver enzymes among different patients groups of District Gujrat, Pakistan

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Advances in Bioscience and Biotechnology 2013年第9期4卷 866-871页

作者： Asim Mushtaq Mujahid Azeem Tariq Umer rashid Amber Afroz Nadia Zeeshan abdul R. Asif Muzna Zahur Department of Biochemistry and Molecular Biology University of Gujrat Gujrat Pakistan Department of Clinical Chemistry University Medical Centre Goettingen Germany Department of Pathology Hashmat Medical College Gujrat Pakistan

Hepatitis C has a 3% of the global disease burden that remains endemic in many regions of the world. According to a general statistical survey it has approximately 5.3% seroprevalence in Pakistan. HCV is a persistent and silent disease thus making the primary diagnosis complicated. Occasionally HCV positive population could not be diagnosed by routine HCV antibody testing therefore requires molecular diagnosis. This study is aimed to determine the prevalence of HCV and to estimate the HCV viral load by quantitative analysis among different patient groups of District Gujrat, Pakistan. A total of 597 samples were collected from clinically diagnosed liver patients that were categorized into three age groups: 1) up to 25 years;2) 26-50 years 3) above 50 years. All samples were subjected to real time PCR for determination and quantification of HCV RNA. Activity of liver aminotransferases was measured. The overall prevalence of HCV-RNA was 73.87%. Females had slightly higher HCV prevalence which is 74.06% while 73.45% in males. Highest prevalence of active HCV infection was found in age group 26-50. In addition, liver function tests showed that 28.12% HCV-positive patients do not have elevated ALT level whereas 32.65% did not show elevated AST levels. It may be assumed that there is not a significant relationship between increased viral load and liver amino transferases. The study concluded a significantly higher rate of HCV infection in young population. Moreover screening with antibody and liver function tests alone does not exclude the possibility of HCV infection.

关键词： Hepatitis C Viral Load Alanine Aminotransferase Aspartate Aminotransferase HCV RNA Gujrat

A Novel Topology of Single-Phase AC-DC Integrated Boost-SEPIC (IBS) Converter Using Common Part Sharing Method (CPSM) for High Step-Up Applications

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Journal of Power and Energy Engineering 2018年第6期6卷 38-47页

作者： Mohammad Bazlur rashid Mohammad abdul Moin Oninda Fahim Faisal Mirza Muntasir Nishat Golam Sarowar Md. Ashraful Hoque Department of Electrical and Electronic Engineering Islamic University of Technology Gazipur Bangladesh

A novel topology of Integrated Boost-SEPIC (IBS) AC-DC converter using common part sharing method (CPSM) has been proposed in this paper. Conventional boost converters with bridge rectifier configuration are inefficient due to limited voltage step-up ratio which may not be applicable for high step-up applications as in the case of micro generators. The proposed IBS topology is based on the common part sharing method capable of operating both for positive and negative half cycle of the input signal. Result and simulation were conducted using PSIM environment. The proposed AC-DC IBS topology eliminates the requirement of bridge rectifier achieving high efficiency (about 99%), improved power factor (0.75, leading) and lower THD (about 38.8%) which is within IEEE standard.

关键词： Integrated Boost-SEPIC (IBS) Bridgeless AC-DC Converter Voltage Gain THD Minimization Efficiency Improvement Power Factor Correction

Extracellular vesicles as tools and targets in therapy for diseases

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Signal Transduction and Targeted Therapy 2024年第3期9卷 872-912页

作者： Mudasir A.Kumar Sadaf K.Baba Hana Q.Sadida Sara Al.Marzooqi Jayakumar Jerobin Faisal H.Altemani Naseh Algehainy Mohammad A.Alanazi abdul-Badi Abou-Samra Rakesh Kumar Ammira S.Al-Shabeeb Akil Muzafar A.Macha rashid Mir Ajaz A.Bhat Watson-Crick Centre for Molecular Medicine Islamic University of Science and TechnologyAwantiporaKashmir 192122India Department of Human Genetics-Precision Medicine in Diabetes Obesity and Cancer ProgramSidra MedicineDohaQatar Qatar Metabolic Institute Academic Health SystemHamad Medical CorporationDohaQatar Department of Medical Laboratory Technology Prince Fahad Bin Sultan Chair for Biomedical ResearchFaculty of Applied Medical SciencesUniversity of TabukTabukSaudi Arabia School of Biotechnology Shri Mata Vaishno Devi UniversityKatraIndia

Extracellular vesicles(EVs)are nano-sized,membranous structures secreted into the extracellular *** exhibit diverse sizes,contents,and surface markers and are ubiquitously released from cells under normal and pathological *** serum is a rich source of these EVs,though their isolation from serum proteins and non-EV lipid particles poses *** vesicles transport various cellular components such as proteins,mRNAs,miRNAs,DNA,and lipids across distances,influencing numerous physiological and pathological events,including those within the tumor microenvironment(TME).Their pivotal roles in cellular communication make EVs promising candidates for therapeutic agents,drug delivery systems,and disease *** in cancer diagnostics,EV detection can pave the way for early identification and offers potential as diagnostic ***,various EV subtypes are emerging as targeted drug delivery tools,highlighting their potential clinical *** need for non-invasive biomarkers to monitor biological processes for diagnostic and therapeutic purposes remains *** into the unique composition of EVs could unlock advanced diagnostic and therapeutic avenues in the *** this review,we discuss in detail the roles of EVs across various conditions,including cancers(encompassing head and neck,lung,gastric,breast,and hepatocellular carcinoma),neurodegenerative disorders,diabetes,viral infections,autoimmune and renal diseases,emphasizing the potential advancements in molecular diagnostics and drug delivery.

关键词： diseases sized sizes

National guidelines for the diagnosis and treatment of hilar cholangiocarcinoma

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World Journal of Gastroenterology 2024年第9期30卷 1018-1042页

作者： Faisal Saud Dar Zaigham Abbas Irfan Ahmed Muhammad Atique Usman Iqbal Aujla Muhammad Azeemuddin Zeba Aziz Abu Bakar Hafeez Bhatti Tariq Ali Bangash Amna Subhan Butt Osama Tariq Butt abdul Wahab Dogar Javed Iqbal Farooqi Faisal Hanif Jahanzaib Haider Siraj Haider Syed Mujahid Hassan Adnan abdul Jabbar Aman Nawaz Khan Muhammad Shoaib Khan Muhammad Yasir Khan Amer Latif Nasir Hassan Luck Ahmad Karim Malik Kamran rashid Sohail rashid Mohammad Salih abdullah Saeed Amjad Salamat Ghias-un-Nabi Tayyab Aasim Yusuf Haseeb Haider Zia Ammara Naveed Department of Hepatopancreatic Biliary Surgery&Liver Transplant Pakistan Kidney and Liver Institute&Research CentreLahore 54000Pakistan Department of Hepatogastroenterology and Liver Transplantation Dr.Ziauddin University HospitalKarachi 75600SindhPakistan University of Aberdeen Aberdeen B243FXUnited Kingdom Department of Pathology Pakistan Kidney and Liver Institute&Research CentreLahore 54000Pakistan Department of Gastroenterology&Hepatology Pakistan Kidney and Liver Institute&Research CentreLahore 54000Pakistan Department of Radiology Aga Khan UniversityKarachi 74800Pakistan Department of Oncology Hameed Latif HospitalLahore 54000Pakistan Division of Hepatopancreatic Biliary Surgery&Liver Transplantation Shifa International HospitalIslamabad 44000Pakistan Department of Hepatopancreatic Biliary Surgery&Liver Transplant Shaikh Zayed Hospital and Post Graduate Medical InstituteLahore 54000Pakistan Department of Medicine Aga Khan University HospitalKarachi 74800Pakistan Department of Liver Transplant Pir Abdul Qadir Shah Jeelani Institute of Medical SciencesGambat 66020Pakistan Department of Medicine&Gastroenterology Lifecare Hospital and Research CentrePeshawar 25000Khyber PakhtunkhwaPakistan Department of Hepatopancreatobiliary&Liver Transplant Bahria International HospitalLahore 54000Pakistan Department of Surgery Hepatopancreatobiliary&Liver TransplantDow University of Health SciencesKarachi 74800Pakistan Department of Gastroenterology Hepatology&NutritionPir Abdul Qadir Shah Jeelani Institute of Medical SciencesGambat 66020Pakistan Department of Oncology Dr.Ziauddin HospitalKarachi 74800Pakistan Department of Radiology Rehman Medical InstitutePeshawar 25000Pakistan Army Liver Transplant Unit Pak Emirates Military HospitalRawalpindi 46000Pakistan Department of Gastroenterology Sindh Institute of Urology and TransplantationKarachi 75500Pakistan rashid Nursing Home and Cancer Clinic Rashid Nursing Home and Cancer ClinicRawalpindi 46000Pakistan Department of Gastroentero

A consensus meeting of national experts from all major national hepatobiliary centres in the country was held on May 26,2023,at the Pakistan Kidney and Liver Institute&Research Centre(PKLI&RC)after initial consultations with the *** Pakistan Society for the Study of Liver Diseases(PSSLD)and PKLI&RC jointly organised this *** effort was based on a comprehensive literature review to establish national practice guidelines for hilar cholangiocarcinoma(hCCA).The consensus was that hCCA is a complex disease and requires a multidisciplinary team approach to best manage these *** coordinated effort can minimise delays and give patients a chance for curative treatment and effective *** diagnostic and staging workup includes high-quality computed tomography,magnetic resonance imaging,and magnetic resonance *** cytology or biopsy utilizing endoscopic retrograde cholangiopancreatography is a mainstay for ***,histopathologic confirmation is not always required before *** ultrasound with fine needle aspiration of regional lymph nodes and positron emission tomography scan are valuable adjuncts for *** only curative treatment is the surgical resection of the biliary tree based on the Bismuth-Corlette *** patients with unresectable hCCA can be considered for liver *** chemotherapy should be offered to patients with a high risk of *** use of preoperative biliary drainage and the need for portal vein embolisation should be based on local multidisciplinary *** with acute cholangitis can be drained with endoscopic or percutaneous biliary *** chemotherapy with cisplatin and gemcitabine has shown improved survival in patients with irresectable and recurrent hCCA.

关键词： Hilar cholangiocarcinoma Bismuth-Corlette classification Memorial Sloan Kettering Cancer Centre Staging Preoperative biliary drainage Portal vein embolisation Surgical resection Hepatectomy