检索结果-南通市图书馆

Emergency department electric scooter injuries after the introduction of shared e-scooter services: A retrospective review of 3,331 cases

引用

World Journal of Emergency Medicine 2022年第1期13卷 5-10页

作者： Ittai Shichman Or Shaked shai factor Ahuva Weiss-Meilik Amal Khoury Division of Orthopedics Tel-Aviv Sourasky Medical CenterAffi liated to the Sackler Faculty of Medicine Tel-Aviv UniversityTel Aviv 64239Israel Head of I-Medata AI Center Tel-Aviv Sourasky Medical CenterAffi liated to the Sackler Faculty of Medicine Tel-Aviv UniversityTel Aviv 64239Israel

BACKGROUND: To determine the frequency, characteristics, and use of resources related to electric scooter(e-scooter) injuries in the emergency department(ED) of a major metropolitan area ***: We performed a retrospective review of all ED presentations related to e-scooter injuries at a level I trauma center between May 2017 and February 2020. We identified ED presentation data, injury-related data, patients’ clinical course after evaluation, injury diagnosis, surgical procedures, and ED ***: A total of 3,331 patients with e-scooter injuries presented to the ED over a 34-month period. There was a 6-fold increase in e-scooter-related injuries presenting to the ED, from an average of 26.9 injuries per month before the introduction of shared e-scooter services in August 2018 to an average of 152.6 injuries per month after its introduction. The average injury rate during weekdays was 3.27 per day, with the majority of injuries occurring in the afternoon. The most common mechanism of injury was rider fall(79.1%). There were a total of 2,637 orthopedic injuries, of which 599(22.7%) were fractures. A total of 296(8.9%) patients were hospitalized following the initial ED admission, and 462 surgeries were performed within 7 days of ED ***: The introduction of the shared e-scooter services is associated with a dramatic increase in e-scooter injuries presenting to the ED. E-scooter use carries considerably underestimated injury risks of high-energy trauma and misunderstood mechanisms of injuries. These injuries challenge the healthcare system, with a major impact on both EDs and surgical departments.

关键词： E-scooter Scooter Emergency department

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Stepping up to meet the challenge of freezing of gait in Parkinson’s disease

引用

Translational Neurodegeneration 2022年第1期11卷 589-600页

作者： Simon Lewis Stewart factor Nir Giladi Alice Nieuwboer John Nutt Mark Hallett ForeFront Parkinson’s Disease Research Clinic Brain and Mind CentreSchool of Medical SciencesUniversity of SydneySydneyNSWAustralia Jean and Paul Amos Parkinson’s Disease and Movement Disorders Program Emory University School of MedicineAtlantaGAUSA Movement Disorders Unit Department of NeurologyTel-Aviv Sourasky Medical CenterSackler School of Medicine and Sagol School of NeuroscienceTel Aviv UniversityTel AvivIsrael Department of Rehabilitation Sciences KU LeuvenLeuvenBelgium Movement Disorder Section Department of NeurologyOregon Health&Science UniversityPortlandORUSA Human Motor Control Section National Institute of Neurological Disorders and StrokeNational Institutes of HealthBethesdaMDUSA.

There has been a growing appreciation for freezing of gait as a disabling symptom that causes a significant burden in Parkinson’s disease. Previous research has highlighted some of the key components that underlie the phenomenon, but these reductionist approaches have yet to lead to a paradigm shift resulting in the development of novel treatment strategies. Addressing this issue will require greater integration of multi-modal data with complex computational modeling, but there are a number of critical aspects that need to be considered before embarking on such an approach. This paper highlights where the field needs to address current gaps and shortcomings including the standardization of definitions and measurement, phenomenology and pathophysiology, as well as considering what available data exist and how future studies should be constructed to achieve the greatest potential to better understand and treat this devastating symptom.

关键词： Freezing of gait Computational modeling Standardized definitions and assessments Novel paradigms Phenomenology Pathophysiology Treatment

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Preoperative risk factor analysis in orthotopic liver transplantation with pretransplant artificial liver support therapy

引用

World Journal of Gastroenterology 2006年第31期12卷 5055-5059页

作者： Jin-Zhong Yuan Qi-Fa Ye Ling-Ling Zhao Ying-Zi Ming Hong Sun shai-Hong Zhu Zu-Fa Huang Min-Min Wang Blood Purification Center Xiangya Transplantation Institute Third Xiangya Hospital of Central South University Changsha 410013 Hunan Province China

AIM： To assess the value of pre-transplant artificial liver support in reducing the pre-operative risk factors relating to early mortality after orthotopic liver transplantation （OLT）. METHODS： Fifty adult patients with various stages and various etiologies undergoing OLT procedures were treated with molecular adsorbent recycling system （MARS） as preoperative liver support therapy. The study included two parts, the first one is to evaluate the medical effectiveness of single MARS treatment with some clinical and laboratory parameters, which were supposed to be the therapeutical pre-transplant risk factors, the second part is to study the patients undergoing OLT using the regression analysis on preoperative risk factors relating to early mortality （30 d） after OLT. RESULTS： In the 50 patients, the statistically significant improvement in the biochemical parameters was observed （pre-treatment and post-treatment）. Eight patients avoided the scheduled Ltx due to significant relief of clinical condition or recovery of failing liver function, 8 patients died, 34 patients were successfully bridged to Ltx, the immediate outcome of this 34 patients within 30d observation was： 28 kept alive and 6 patients died. CONCLUSION： Pre-operative SOFA, level of creatinine, INR, TNF-α, IL-10 are the main preoperative risk factors that cause early death after operation, MARS treatment before transplantion can relieve these factors significantly.

关键词： Liver transplantation Artificial liver Sequential Organ Failure Assessment Risk factors analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Droplet Raman laser coupled to a standard fiber

引用

Photonics Research 2019年第10期7卷 1188-1192页

作者： shai MAAYANI TAL CARMON Research Laboratory of Electronics Massachusetts Institute of TechnologyCambridgeMassachusetts 02139USA Technion—Israel Institute of Technology Faculty of Mechanical EngineeringHaifa 3200003Israel

We fabricate a tapered fiber coupler, position it near an ultrahigh-Q resonator made from a microdroplet, and experimentally measure stimulated Raman emission. We then calculate the molecular vibrational mode associated with each of the Raman lines and present it in a movie. Our Raman laser lines show themselves at a threshold of 160 μW input power, the cold-cavity quality factor is 250 million, and mode volume is 23 μm^3. Both pump and Raman laser modes overlap with the liquid phase instead of just residually extending to the fluid.

关键词： fiber laser pump

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Assessment of the Bemisia tabaci C YP6CM l vQ transcript and protein levels in laboratory and field-derived imidacloprid-resistant insects and cross-metabolism potential of the recombinant enzyme

引用

Insect Science 2011年第1期18卷 23-29页

作者： Emmanouil Roditakis Evangelia Morou Anastasia Tsagkarakou Maria Riga Ralf Nauen Mark Paine shai Morin John Vontas Laboratory of Entomology and Agricultural Zoology Plant Protection Institute of Heraklion National Agricultural Research Foundation Heraklion (N.AG.RE.F.) Heraklio Greece Faculty of Applied Biology and Biotechnology Department of Biology University of Crete Heraklion Greece Vector Group Liverpool School of Tropical Medicine Liverpool UK Bayer CropScience AG Research Insecticides Insect Toxicology and Resistance Monheim Germany Department of Entomology Faculty of Agricultural Food and Environmental Quality Sciences Hebrew University of Jerusalem Rehovot Israel

Over-expression of the cytochrome P450 CYP6CM1 gene has been associated with imidacloprid resistance in a number of Q and B biotype Bemisia tabaci laboratory strains from distinct geographical origins worldwide. We recently demonstrated that the Q biotype version of the CYP6CM 1 protein （CYP6CMlvQ） is capable of metabolizing imida- cloprid. Here, we show that the levels of BtCYP6CMlvQ were also elevated in laboratory- resistant strains and field-derived populations, with variable imidacloprid resistance levels, collected in Crete. High levels of CYP6CMlvQ transcripts were also determined in survivors of a heterogeneous field population, after exposure to discriminating imidacloprid dosage. Using peptide antibody-based detection assays, we demonstrated that in line with transcriptional data, the CYP6CMlvQ protein levels were higher in imidacloprid-resistant insects, which further implicates the gene as the causal factor of resistance. Finally, assess- ment of the cross-metabolism potential of CYP6CMlvQ against additional neonicotinoid molecules used for B. tabaci control revealed that clothianidin and thiacloprid, but not acetamiprid or thiamethoxam, are metabolized by the recombinant enzyme in vitro.

关键词： detoxification neonicotinoids peptide antibodies P450

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

如何建立合理有效的重症监护病房

引用

中华结核和呼吸杂志 2013年第6期36卷 469-471页

作者：乔人立 Phillip H factor Pulmonary and Critical Care Medicine University of Southern California Los Angeles California Columbia University New York NYUSA

ICU正迅速成为现代医院运行的核心。在美国，ICU床位虽然只占医院病床的5％左右，但ICU患者的住院费用却占医院总医疗消费的30％以上，而且ICU平均病死率为30％，是所有住院患者的10倍。随着人口老龄化与住院患者结构越来越偏向病情较... 详细信息

ICU正迅速成为现代医院运行的核心。在美国，ICU床位虽然只占医院病床的5％左右，但ICU患者的住院费用却占医院总医疗消费的30％以上，而且ICU平均病死率为30％，是所有住院患者的10倍。随着人口老龄化与住院患者结构越来越偏向病情较严重者，未来ICU床位需求势必进一步增加。因此，ICU的建设与管理无论从医疗还是经营角度上讲都非常重要。目前世界各地ICU组织管理模式差异很大，本文从多个方面系统地介绍美国ICU系统，期望为国内同行开展ICU工作提供借鉴。

关键词：重症监护病房 ICU患者组织管理模式医院运行医疗消费住院患者人口老龄化医院病床

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The miR166-SIHB15A regulatory module controls ovule development and parthenocarpic fruit set under adverse temperatures in tomato

引用

Molecular Plant 2021年第7期14卷 1185-1198页

作者： Christian Clepet Ravi Sureshbhai Devani Rachid Boumlik Yanwei Hao Halima Morin Fabien Marcel Marion Verdenaud Brahim Mania Gwilherm Brisou Sylvie Citerne Gregory Mouille Jean-Christophe Lepeltier shai Koussevitzky Adnane Boualem Abdelhafid Bendahmane Institute of Plant Sciences Paris-Saclay INRAECNRSUniversite Paris-SaclayOrsay 91405France HM Clause Mas Saint-PierreQuartier La GalineSaint-Remy de Provence 13210France Hazera Seeds Ltd Berurim M.P.Shikmim 7983700Israel lnstitut Jean-Pierre Bourgin INRAEVersaillesFrance Present address:Key Laboratory of Horticultural Crop Biology and Germplasm Innovation in South China College of HorticultureSouth China Agricultural UniversityGuangzhou 510642China

Fruit set is inhibited by adverse temperatures,with consequences on *** isolated a tomato mutant producing fruits under non-permissive hot temperatures and identified the causal gene as SIHB15A,belonging to classⅢhomeodomain leucine-zipper transcription ***15A,loss-of-function mu-tants display aberrant ovule development that mimics transcriptional changes occurring in fertilized ovules and leads to parthenocarpic fruit set under optimal and non-permissive temperatures,in field and greenhouse *** cold growing conditions,SIHB15A is subjected to conditional haploinsufficiency and recessive dosage sensitivity controlled by microRNA 166(miR166).Knockdown of SIHB15A alleles by miR166 leads to a continuum of aberrant ovules correlating with parthenocarpic fruit *** with this,plants harboring an Slhb15a-miRNA166-resisiant allele developed normal ovules and were unable to set parthenocarpic fruit under cold *** affinity purification sequencing and RNA-sequencing analyses revealed that SIHB15A is a bifunctional transcription factor expressed in the ovule ***15A binds to the promoters of auxin-related genes to repress auxin signaling and to the promoters of ethylene-related genes to activate their expression.A survey of tomato genetic biodiversity identified pat and pat-1,two historical parthenocarpic mutants,as alleles of *** together,our findings demonstrate the role of SIHB15A as a sentinel to prevent fruit set in the absence of fertilization and provide a mean to enhance fruiting under extreme temperatures.

关键词： parthenocarpy dosage sensitivity HD-Ziplll miRNA166 heat stress cold stress

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

假说:充血性心肌病是否系心肌微循环过度反应(微血管痉挛)所引起?

引用

国外医学.心血管疾病分册 1983年第3期 132-134页

作者： factor SM 陈灏珠

心肌收缩力减弱是充血性心肌病的常见表现,可导致明显的充血性心力衰竭.一般认为,大多数心肌病的心室功能障碍是心肌细胞广泛受损的结果,不论是由于病毒、代谢障碍、毒素(如酒精)或不明原因的损害所致.虽然遗传性代谢病如α-1,4葡萄糖... 详细信息

心肌收缩力减弱是充血性心肌病的常见表现,可导致明显的充血性心力衰竭.一般认为,大多数心肌病的心室功能障碍是心肌细胞广泛受损的结果,不论是由于病毒、代谢障碍、毒素(如酒精)或不明原因的损害所致.虽然遗传性代谢病如α-1,4葡萄糖甙酶缺乏(PompeⅡ型糖元贮积病)确可引起弥漫性肌细胞病变,但大多数充血性心肌病在组织

关键词：微循环局灶性动物模型发病机理病变心肌细胞心肌疾病血管痉挛

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Clinical guideline on topical growth factors for skin wounds

引用

Burns & Trauma 2020年第1期8卷 106-115页

作者： Chun-mao Han Biao Cheng PanWu writing group of growth factor guideline on behalf of Chinese Burn Association Department of Burns&Wound Care Center the Second Affiliated Hospital of Zhejiang University School of MedicineNo.88 Jiefang RoadHangzhou 310009China Department of Burns&Plastic Surgery General Hospital of Southern Theater CommandPLANo.111 Liuhua RoadGuangzhou 510000China 不详

An increased number of patients with skin wounds have been witnessed in the past *** the various kinds of treatments for skin wounds,topical exogenous growth factors are indispensable and have been used in many ***,whether they have reliable effects remains controversial,and their application for skin wound treatment needs to be further standardized and optimized in terms of socio-economic ***,the Chinese Burn Association developed this guideline indicating efficacy,application details,adverse reactions and precautions of five clinically common topical growth factors using the Grading of Recommendations Assessment Development and Evaluation method to promote the rational application of topical exogenous growth factors in skin wounds and to benefit more patients.

关键词： Growth factor Skin wound Wound healing GRADE method Guideline

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effect of cytokines on liver necrosis

引用

World Journal of Gastroenterology 1998年第4期4卷 39-41页

作者： YU YanYan1, SI ChongWen1, TIAN XiuLan1, HE Qun2 and XUE HaiPeng2Keywords hepatitis liver necrosis tumor necrosis factor interleukins interferon

AIM To investigate the effect of cytokines on the liver *** rIL (interleukin)-1, rIL-6, rIFN (interferon), rTNF (tumor necrosis factor) α with or without D-galactosamine (D-GAL) were injected into the abdominal cavity of mice separately. ALT, TBIL (total bilirubin) and histological changes were *** There was no effect on hepatocyte of normal mice after injection of rIL-1, rIL-6, rIFN alone or together. The serum total bilirubin (TBIL) and liver necrosis of mice increased after rTNFα, rIL-6 or rIFN were used separately with D-GAL. The TBIL level (μmol/L) was 46.19±10.62, 44.55±12.9 and 41.94±14.9, higher than that caused by D-GAL alone (TBIL, 26.67μmol/L±11.14μmol/L). The serum TBIL of mice and the degree of liver necrosis increased after injection of IL-1, IL-6 with D-GAL and rTNFα.CONCLUSION Cytokines, like IL-1,IL-6, IFN and TNFα joined in the process of hepatocyte necrosis. They can enhance the degree of liver necrosis induced by D-GAL.

关键词： cytokines

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：