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Developing Engagement in the Learning Management System Supported by Learning Analytics

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Computer Systems Science & Engineering 2022年第7期42卷 335-350页

作者： Suraya Hamid shahrul nizam ismail Muzaffar Hamzah Asad W.Malik Department of Information System Faculty of Computer Science and Information TechnologyUniversiti MalayaKuala LumpurMalaysia Faculty of Computing and Informatics Universiti Malaysia SabahSabahMalaysia Department of Computing School of Electrical Engineering and Computer Science(SEECS)National University of Sciences and Technology(NUST)IslamabadPakistan

Learning analytics is an emerging technique of analysing student par-ticipation and *** recent COVID-19 pandemic has signiﬁcantly increased the role of learning management systems(LMSs).LMSs previously only complemented face-to-face teaching,something which has not been possible between 2019 to *** date,the existing body of literature on LMSs has not analysed learning in the context of the pandemic,where an LMS serves as the only interface between students and ***,productive results will remain elusive if the key factors that contribute towards engaging students in learning are notﬁrst identiﬁ***,this study aimed to perform an exten-sive literature review with which to design and develop a student engagement model for holistic involvement in an *** required data was collected from an LMS that is currently utilised by a local Malaysian *** model was validated by a panel of experts as well as discussions with *** is our hope that the result of this study will help other institutions of higher learning determine factors of low engagement in their respective LMSs.

关键词： Engagement analysis learning analytics learning management system student engagement

Trichomonas vaginalis infection in a low-risk women attended in Obstetrics and Gynaecology Clinic, Universiti Kebangsaan Malaysia Medical Centre

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Asian Pacific Journal of Tropical Biomedicine 2016年第8期6卷 702-705页

作者： Norhayati Moktar Nor Liyana ismail Phoy Cheng Chun Mohamad Asyrab Sapie Nor Farahin Abdul Kahar Yusof Suboh Noraina Abdul Rahim Nor Azlin Mohamed ismail Tengku shahrul Anuar Department of Parasitology and Medical Entomology Universiti Kebangsaan Malaysia Medical Centre Department of Obstetrics and Gynaecology Universiti Kebangsaan Malaysia Medical Centre Department of Medical Laboratory Technology Faculty of Health Sciences Universiti Teknologi MARAPuncak Alam Campus

Objective: To investigate the presence of trichomoniasis among women attending the Obstetrics and Gynaecology Clinic, Universiti Kebangsaan Malaysia Medical ***: A total of 139 high vaginal swabs were taken from the subjects and sent to the laboratory in Amies gel transport media. The specimens were examined for the presence of Trichomonas vaginalis using wet mount, Giemsa staining and cultured in Diamond's medium. Sociodemographic characteristics and gynaecological complaints were obtained in private using structured questionnaire applied by one ***: The median age was 32 years, with an interquartile interval of 9.96. Most of the subjects were Malays(76.9%) and the remaining were Chinese(15.1%), Indians(2.2%)and other ethnic groups(5.8%). One hundred and thirty eight(99.3%) of the women were married and 98.6% had less than 6 children. More than half(75.5%) of the women's last child birth was less than 6 years ago. Forty seven percent of them were involved in supporting administrative work and 64.7% of the women gave a history of previous or current vaginal ***: The present study reported zero incidence rate of trichomoniasis. The low incidence rate was postulated due to all women who participated in this study were categorized into a low-risk group.

关键词： Trichomoniasis Incidence rate Wet mount Giemsa staining Culture

Methanolic extract of Abrus precatorius promotes breast cancer MDA-MB-231 cell death by inducing cell cycle arrest at G0/G1 and upregulating Bax

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Asian Pacific Journal of Tropical Biomedicine 2019年第6期9卷 249-256页

作者： Wan Suriyani Wan-Ibrahim Norzila ismail Siti Farhanah Mohd-Salleh Aidy Irman Yajid Michael Pak-KaiWong Mohd nizam Md Hashim Department of Pharmacology School of Medical SciencesUniversiti Sains Malaysia16150Kubang KerianKelantanMalaysia Department of Pathology School of Medical SciencesUniversiti Sains Malaysia16150Kubang KerianKelantanMalaysia Department of Surgery School of Medical SciencesUniversiti Sains Malaysia16150Kubang KerianKelantanMalaysia

Objective:To determine the anti-proliferative activity of Abrus precatorius(***)leaf extracts and their effect on cell ***:*** leaves were extracted successively with hexane,ethyl acetate and methanol by Soxhlet *** extract was prepared by decoction at 50 ℃.Extracts of *** leaves were used to treat selected cancer and normal cell lines for72 ***,3-(4,5-dimethyl thiazol-2-yl)2,5-diphenyl tetrazolium bromide assay was performed to determine cell *** of cell cycle arrest,apoptosis assay and apoptosis protein expressions were determined by flow ***:Methanolic extract of *** leaves showed the lowest IC50 on MDA-MB-231 cells at(26.40±5.40)μg/*** cytometry analysis revealed that cell arrest occurred at G0/G1 phase and the apoptosis assay showed the occurrence of early apoptosis at 48 h in MDAMB-231 cells treated with methanolic extract of *** *** extract of *** leaves induced apoptosis by upregulation of Bax,p53 and caspase-3 and downregulation of ***:Methanolic extract of A precatorius leaves promotes MDA-MB-231 cell death by inducing cell cycle arrest and apoptosis possibly via the mitochondrial-related pathway.

关键词： Abrus precatorius MDA-MB-231 Apoptosis Cell cycle Breast cancer

Phytocompounds of Anonna muricata leaves extract and cytotoxic effects on breast cancer cells

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Asian Pacific Journal of Tropical Medicine 2018年第12期11卷 659-665页

作者： Husna Syakirah Ab Rahman Wan Suriyani Wan-Ibrahim Norzila ismail Tuan Nadrah Naim Tuan ismail Siti Farhanah Mohd-Salleh Michael Pak-Kai Wong Mohd Ridzuan Abdul Samad Mohd nizam Md Hashim Department of Surgery School of Medical Sciences Universiti Sains Malaysia Department of Pharmacology School of Medical Sciences Universiti Sains Malaysia School of Dental Sciences Universiti Sains Malaysia

Objective: To identify the phytochemical compounds from Annona muricata(A. muricata) and to determine their in vitro anti-proliferative activities against breast cancer cells, MCF7 and MDA-MB-231. Methods: A. muricata leaves were successively extracted by soxhlet method using n-hexane, ethyl acetate and methanol, and decocted with water. Each extract was analysed by gas chromatography mass spectrometry(GCMS) and characterized with Wiley and NIST library searches. Anti-proliferative activity of each extract was evaluated on MCF7 and MDA-MB-231 breast cancer cells using MTT assay. Results: The GCMS analysis of different solvent extracts of A. muricata leaves showed presence of different chemical groups of compounds such as steroids, terpenoids, phenolic compounds, sugars, sugars alcohol and others including vitamin E. Ethyl acetate leaves extract exhibited the lowest IC_(50) value on the MDA-MB-231 breast cancer cell and n-hexane leaves extract showed the the lowest IC_(50) value on the MCF-7 breast cancer cell. Conclusion: Steroids and phenolic compounds were the main phytocompound groups identified from all A. muricata leaves extracts. The antiproliferative activity of n-hexane and ethyl acetate extract towards breast cancer MCF7 and MDA-MB-231 respectively might be due to the presence of biologically active compounds in the extracts, hence, providing some scientific evidences of the effectiveness of its traditional usages.

关键词： Annona muricata GCMS Anti-proliferative Breast cancer Graviola

Eco-friendly method for synthesis of zeolitic imidazolate framework 8 decorated graphene oxide for antibacterial activity enhancement

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Particuology 2020年第2期18卷 24-32页

作者： Nazerah Ahmad Nik Abdul Hadi Md Nordin Juhana Jaafar Nik Ahmad nizam Nik Malek Ahmad Fauzi ismail Muhammad Nabil Fikri Yahya Siti Aishah Mohd Hanim Mohd Sohaimi Abdullah Advanced Membrane Technology Research Centre Universiti Teknologi Malaysia81310 SkudaiJohorMalaysia Malaysian Institute of Chemical Engineering Technology-Universiti Kuala Lumpur Lot 1988Bandar VendorTaboh Naning78000 Alor GajahMelakaMalaysia Chemical Engineering Department Universiti Teknologi PETRONAS32610 Seri IskandarPerakMalaysia Department of Biosciences Faculty of ScienceUniversiti Teknologi Malaysia81310 SkudaiJohorMalaysia Centre for Student Innovation and Technology Entrepreneurship Universiti Teknologi Malaysia81310 SkudaiJohorMalaysia

We report a rapid method for synthesis of zeolitic imidazolate framework 8(ZIF-8)-decorated graphene oxide(GO)composites(ZGO)with good antibacterial *** ZGO composites were synthesized at room temperature with low GO to metal salt *** samples were characterized by X-ray diffraction,transmission electron microscopy,Fourier transform infrared spectroscopy,thermal gravimetric analysis,and surface area *** characterization results show that ZIF-8 with a size of approximately 120 nm is successfully decorated on the surface of GO sheets with the host ZIF-8 framework maintained in the synthesized composite,but there is a significant reduction in the Brunauer-Emmett-Teller surface *** antibacterial activities of the samples against Escherichia coli ATCC 11229 and Staphylococcus aureus ATCC 6538 as model strains of gram-negative and-positive bacteria,respectively,were determined by disc diffusion and minimum inhibitory concentration(MIC)***-1.0(1 wt%of ratio of GO to metal salt)shows the highest antibacterial activity with MIC values required to inhibit bacterial growth of *** and *** of 5 times lower than those of pristine *** antibacterial mechanisms are proposed based on field-emission scanning electron microscope images of the two bacteria after contact with the synthesized ***,owing to the simple synthesis,good stability,low chemical usage,and excellent antibacterial activity of the ZGO composites,they show great potential for application in the field of microbial contamination control.

关键词： Graphene oxide Metal-organic framework Hybrid nanocomposite Zeolitic imidazolate framework Antibacterial agent

The Internationalisation of Malaysian SMEs

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The Internationalisation of Malaysian SMEs

Hepatic and renal effects of oral stingless bee honey in a streptozotocin-induced diabetic rat model

2011 International Conference on Sociality and Economics Development（ICSED 2011）

作者： Nik Ab Halim Nik Abdullah shahrul nizam Mohd Zain College of Business Universiti Utara Malaysia

This paper presents the descriptive analysis of a study on internationalisation among Malaysian *** objective is to highlight the number of firms that do involve in international market,reason for internationalisation and their mode of entry into foreign *** SMEs that do not internationalise,the concern is more towards the reason why they did *** are based on the related theories of internationalisation namely the Uppsala Model,Network Approach and International New Venture or Born *** were collected through self-administered questionnaire and a total of 250 responds were *** indicate that exporting was the most used mode of entry and increasing profit was the main reason for *** internationalisation processes were adopted but the step-by-step and cautious approach seems to be the most *** difficulties and uncertainties in making profit appear to be the major reason for SMEs that did not *** analysis has been conducted to look at the characteristics of SMEs that *** of the findings,significance of the study and direction for future research are then discussed.

关键词： Internationalisation Small and medium enterprises entry mode Malaysia

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World Journal of Experimental Medicine 2024年第1期14卷 113-123页

作者： Suriati Mohd Nasir Anis Farihan ismail Tuan Salwani Tuan ismail Wan Faiziah Wan Abdul Rahman Wan Amir nizam Wan Ahmad Tengku Ahmad Damitri Al-Astani Tengku Din Kuttulebbai Nainamohammed Salam Sirajudeen Department of Chemical Pathology School of Medical SciencesUniversiti Sains MalaysiaKota Bharu 16150KelantanMalaysia Endocrinology Laboratory Department of Chemical PathologySchool of Medical SciencesUniversiti Sains MalaysiaKota Bharu 16150KelantanMalaysia Department of Pathology School of Medical SciencesUniversiti Sains MalaysiaKota Bharu 16150KelantanMalaysia Biomedicine Program School of Health SciencesHealth CampusUniversiti Sains MalaysiaKota Bharu 16150KelantanMalaysia Department of Basic Medical Sciences Kuliyyah of MedicineInternational Islamic University MalaysiaBandar Indera MahkotaKuantan 25200PahangMalaysia

BACKGROUND Diabetes is known damage the liver and kidney,leading to hepatic dysfunction and kidney *** is believed to help in lowering the blood glucose levels of diabetic patients and reducing diabetic ***,the effect of stingless bee honey(SBH)administration in relieving liver and kidney damage in diabetes has not been *** To investigate the effect of SBH administration on the kidney and liver of streptozotocin-induced(STZ;55 mg/kg)diabetic Sprague Dawley *** The rats were grouped as follows(n=6 per group):non-diabetic(ND),untreated diabetic(UNT),metformin-treated(MET),and SBH+metformin-treated(SBME)*** successful diabetic induction,ND and UNT rats were given normal saline,whereas the treatment groups received SBH(2.0 g/kg and/or metformin(250 mg/kg)for 12 *** biochemical parameters and histological changes using hematoxylin and eosin(H&E)and periodic acid–Schiff(PAS)staining were *** On H&E and PAS staining,the ND group showed normal architecture and cellularity of Bowman’s capsule and tubules,whereas the UNT and MET groups had an increased glomerular cellularity and thickened basement *** SBH-treated group showed a decrease in hydropic changes and mild cellularity of the glomerulus vs the ND group based on H&E staining,but the two were similar on PAS ***,the SBME-treated group had an increase in cellularity of the glomerulus on H&E staining,but it was comparable to the SBH and ND groups on PAS *** diabetic rats had tubular hydropic tubules,which were smaller than other *** fatty vacuole formation and dilated blood sinusoids in liver tissue were seen in the SBH ***,the UNT group had high glucose levels,which subsequently increased MDA levels,ultimately leading to liver *** treatment reduced this damage,as evidenced by having the lowest fasting glucose,serum alanine transaminase,aspartate transaminase,and alkaline phosphatase l

关键词： Diabetes Streptozotocin Stingless bee honey Hematoxylin and eosin Periodic acid-Schiff Liver Kidney

A comparative study of conventional and supercritical fluid extraction methods for the recovery of secondary metabolites from Syzygium campanulatum Korth

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2016年第9期17卷 683-691页

作者： Abdul Hakeem MEMON Mohammad shahrul Ridzuan HAMIL Madeeha LAGHARI Fahim RITHWAN Salman ZHARI Mohammed Ali Ahmed SAEED Zhari ismail Amin Malik Shah Abdul MAJID Department of Pharmaceutical Chemistry School of Pharmaceutical Sciences Universiti Sains Malaysia 11800 Minden Penang Malaysia Center of Lipids Engineering and Applied Research (CLEAR) lbnu Sina Institute for Scientific & Industrial Research (lbnu Sina ISIR) Universiti Teknologi Malaysia 81310 Johor Bahru Johor Malaysia EMAN Research and Testing Laboratory School of Pharmaceutical Sciences Universiti Sains Malaysia 11800 Minden Penang Malaysia

Syzygium campanulatum Korth is a plant, which is a rich source of secondary metabolites （especially flavanones, chalcone, and triterpenoids）. In our present study, three conventional solvent extraction （CSE） techniques and supercritical fluid extraction （SFE） techniques were performed to achieve a maximum recovery of two flavanones, chalcone, and two triterpenoids from S. campanulatum leaves. Furthermore, a Box-Behnken design was constructed for the SFE technique using pressure, temperature, and particle size as independent variables, and yields of crude extract, individual and total secondary metabolites as the dependent variables. In the CSE procedure, twenty extracts were produced using ten different solvents and three techniques （maceration, soxhletion, and reflux）. An enriched extract of five secondary metabolites was collected using n-hexane：methanol （1：1） soxhletion. Using food-grade ethanol as a modifier, the SFE methods produced a higher recovery （25.5%-84.9%） of selected secondary metabo- lites as compared to the CSE techniques （0.92%-66.00%）.

关键词： Syzygium campanulatum Supercritical fluid extraction Conventional solvent extractions Flavanones Chalcone Triterpenoids

血清血脂分析结果与2型糖尿病患者视网膜硬性渗出的关系(英文)

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国际眼科杂志 2009年第4期9卷 627-630页

作者： Amelah Mohamed Abdul Qader Zunaina Embong Bakiah Shaharuddin shahrul Bariyah Sahul Hamid Shatriah ismail 马来西亚理科大学医学院眼科马来西亚理科大学医学院化学病理科

目的:研究血脂分析结果与糖尿病性视网膜病之间的关系,以及2型糖尿患者合并其他系统疾病之间氧化低密度脂蛋白的关系。方法:横断面研究,包括40位糖尿病并糖尿病性视网膜病患者和40位糖尿病不并有糖尿病性视网膜病患者。收集人口学资料,... 详细信息

目的:研究血脂分析结果与糖尿病性视网膜病之间的关系,以及2型糖尿患者合并其他系统疾病之间氧化低密度脂蛋白的关系。方法:横断面研究,包括40位糖尿病并糖尿病性视网膜病患者和40位糖尿病不并有糖尿病性视网膜病患者。收集人口学资料,进行详细眼科检查。空腹采集9mL静脉血,分析血清胆固醇,甘油三酯,高密度脂蛋白,低密度脂蛋白,氧化低密度脂蛋白和糖化血红蛋白。结果:糖尿病性视网膜病组平均血清胆固醇为5.9±1.86mmol/L,非糖尿病性视网膜病组为5.0±1.03mmol/L(P=0.001)。糖尿病性视网膜病组血清低密度脂蛋白为3.6±1.69mmol/L,而对照组为3.0±1.02mmol/L(P=0.005)。与轻至中度视网膜硬性渗出患者比较,重度视网膜硬性渗出患者血清胆固醇,甘油三酯和低密度脂蛋白较高,但是差异无统计学意义(P=0.082, 0.116, 0.218)。重度硬性渗出患者的平均血清氧化低密度脂蛋白较轻至中度者高。糖尿病病史长短以及是否合并其他系统疾病之间平均氧化低密度脂蛋白无统计学显著性差异。结论:血清胆固醇和低密度脂蛋白与糖尿病性视网膜病显著相关,而血清血脂分析结果与视网膜硬性渗出严重度不相关。我们研究发现,血清氧化低密度脂蛋白与糖尿病性视网膜病及合并的其他系统疾病之间无相关关系。

关键词：视网膜硬性渗出血脂分析 2型糖尿病