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Near-infrared brain functional characteristics of mild cognitive impairment with sleep disorders

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World Journal of Psychiatry 2025年第1期15卷 106-116页

作者： Heng Liao sha Liao Yu-Jiao Gao Xi wang Li-Hong Guo Su Zheng Wu Yang Yi-Nan Dai Sleep Psychosomatic Medicine Center Taihe Hospital of Shiyan CityAffiliated Hospital of Hubei University of MedicineShiyan 442000Hubei ProvinceChina Department of Integrated Chinese and Western Medicine Taihe Hospital of Shiyan CityAffiliated Hospital of Hubei University of MedicineShiyan 442000Hubei ProvinceChina Department of Orthopaedics Taihe Hospital of Shiyan CityAffiliated Hospital of Hubei University of MedicineShiyan 442000Hubei ProvinceChina Department of Rehabilitation Taihe Hospital of Shiyan CityAffiliated Hospital of Hubei University of MedicineShiyan 442000Hubei ProvinceChina

BACKGROUND Mild cognitive impairment(MCI)has a high risk of progression to Alzheimer’s *** disease is often accompanied by sleep disorders,and whether sleep disorders have an effect on brain function in patients with MCI is *** To explore the near-infrared brain function characteristics of MCI with sleep *** A total of 120 patients with MCI(MCI group)and 50 healthy subjects(control group)were *** subjects underwent the functional near-infrared spec-troscopy *** baseline data,Mini-Mental State Examination,Montreal Cognitive Assessment scale,fatigue severity scale(FSS)score,sleep parameter,and oxyhemoglobin(Oxy-Hb)concentration and peak time of functional near-infrared spectroscopy test during the task *** relationship between Oxy-RESULTS Compared with the control group,the FSS score of the MCI group was higher(t=11.310),and the scores of Pittsburgh sleep quality index,sleep time,sleep efficiency,nocturnal sleep disturbance,and daytime dysfunction were higher(Z=-10.518,-10.368,-9.035,-10.661,-10.088).Subjective sleep quality and total sleep time scores were lower(Z=-11.592,-9.924).The sleep efficiency of the MCI group was lower,and the awakening frequency,rem sleep latency period,total sleep time,and oxygen desaturation index were higher(t=5.969,5.829,2.887,3.003,5.937).The Oxy-Hb concentration at T0,T1,and T2 in the MCI group was lower(t=14.940,11.280,5.721),and the peak time was higher(t=18.800,13.350,9.827).In MCI patients,the concentration of Oxy-Hb during T0 was negatively correlated with the scores of Pittsburgh sleep quality index,sleep time,total sleep time,and sleep efficiency(r=-0.611,-0.388,-0.563,-0.356).It was positively correlated with sleep efficiency and total sleep time(r=0.754,0.650),and negatively correlated with oxygen desaturation index(r=-0.561)and FSS score(r=-0.526).All comparisons were P<*** Patients with MCI and sleep disorders have lower near-infrared brain function than norm

关键词： Mild Cognitive impairment Sleep disorders Near-infrared Brain functional Characteristics

Dynamically self-adjustable liquid-liquid and self-adaptive softcontact solid-solid triboelectric nanogenerator for wave energy harvesting

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Nano Research 2025年第1期18卷 404-414页

作者： Yong Long Bingqi Zhao Jianan Niu Yuxiu Liu Wei sha Jiangwen wang Zhong Lin wang Weiguo Hu Guangzhou Institute of Blue Energy Knowledge CityHuangpu DistrictGuangzhou 510555China Beijing Institute of Nanoenergy and Nanosystems Chinese Academy of SciencesBeijing 101400China School of Nanoscience and Technology University of Chinese Academy of SciencesBeijing 100049China

Water wave energy exhibits great potential toalleviate the global energy crisis. However, harvesting andutilizing wave energy are challenging due to its irregularity,randomness, and low frequency. Triboelectric nanogenerators(TENGs) have gained significant attention for harvesting waveenergy with high efficiency. This study presents a novelellipsoidal, pendulum-like TENG integrating both liquid-liquid(L-L) and solid-solid (S-S) triboelectricity (LS-TENG). Thisinnovative design enables continuous wave energy harvestingand self-powered marine environment monitoring under variousconditions, including temperature, humidity, and light intensity. The binary immiscible liquids within the LS-TENG’s innersoft balloon create dynamic, and self-adjustable L-L contact interfaces, significantly increasing the L-L contact area andenhancing L-L contact electrification (CE). The unique self-adaptive, soft S-S contact increases the S-S contact areacompared to traditional hard point contact, better adapting to the irregular movements of waves and promoting efficient S-SCE. The LS-TENG achieves highly efficient wave energy harvesting by coupling L-L and S-S CE. Furthermore, the uniquesoft contact design protects the S-S interfaces from mechanical wear and damage during long-term work. The LS-TENG’snovel structure provides an innovative and effective way for water wave energy harvesting.

关键词： self-adaptive soft-contact solid-solid liquid-liquid self-adjustable triboelectric nanogenerator

基于自相关特性的经验模态分解微机械陀螺去噪方法

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中国惯性技术学报 2016年第4期24卷 537-541页

作者：刘晓光郝沙沙王光磊娄存广刘秀玲河北大学电子信息工程学院保定071002 河北省数字医疗工程重点实验室保定071002

陀螺的噪声是影响组合导航系统精度的重要因素之一。以农机多传感器组合导航系统为研究背景,在分析经验模态分解去噪和小波去噪的基础上,提出了一种基于自相关特性的经验模态分解去噪方法。该方法根据本证模态函数分量的自相关函数特性... 详细信息

陀螺的噪声是影响组合导航系统精度的重要因素之一。以农机多传感器组合导航系统为研究背景,在分析经验模态分解去噪和小波去噪的基础上,提出了一种基于自相关特性的经验模态分解去噪方法。该方法根据本证模态函数分量的自相关函数特性,提出了一种含噪本证模态函数筛选策略。该方法能够自适应地确定主要含噪的本证模态函数分量,避免了需要人为确定的不足;同时,结合改进小波阈值去噪的优势,避免了将混叠在噪声中的有效信号完全消除,使其具有一定的自适应性。为了验证方法的有效性,利用农机组合导航系统中微机械陀螺的实际输出数据,分别采用改进阈值小波去噪方法、经验模态分解去噪和改进的经验模态分解去噪方法进行了对比试验。结果表明,改进经验模态分解去噪方法的效果要优于前者,在一定程度上能够改善农机多传感器组合导航系统的定位精度。

关键词：经验模态分解微机械陀螺去噪数据处理

聚吡咯基本征可拉伸导电纤维构建及电热理疗应用

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高分子学报 2024年第3期55卷 309-319页

作者：李沂蒙李雯昕刘晓莉唐丽琴王莎莎王富军王璐毛吉富东华大学纺织学院纺织面料技术教育部重点实验室、纺织行业生物医用纺织材料与技术重点实验室、上海市现代纺织前沿科学研究基地上海201620

为解决现有可拉伸电极存在的制备工艺复杂和本征可拉伸性能差的问题,采用简单的原位聚合方法,通过优化掺杂剂,开发了一种具有本征可拉伸性的聚吡咯基导电纤维.在导电纤维的制备过程中,磺基水杨酸钠被用作掺杂剂和增塑剂,使得导电纤维展... 详细信息

为解决现有可拉伸电极存在的制备工艺复杂和本征可拉伸性能差的问题,采用简单的原位聚合方法,通过优化掺杂剂,开发了一种具有本征可拉伸性的聚吡咯基导电纤维.在导电纤维的制备过程中,磺基水杨酸钠被用作掺杂剂和增塑剂,使得导电纤维展现出出色的初始电导率(6.34 S/cm),并且在100%拉伸应变下仍保持5.37 S/cm的良好导电性能.此外,基于弹性导电纤维的加热器具有优秀的焦耳热性能.当施加5V电压时,其表面温度可达到60℃,为热疗提供了可靠的加热效果.进一步将导电纤维集成到电热手套中,实验发现在手指关节运动过程中,手套表面温度仅下降了4.89%,可实现对运动关节的稳定热疗.这为雷诺综合征和关节损伤疼痛等疾病的物理治疗提供了便捷有效的实施方案.

关键词：聚吡咯导电纤维本征可拉伸焦耳热热疗

完备与不完备背景关系中蕴含的系统功能结构分析

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计算机科学 2017年第3期44卷 268-273,306页

作者：崔铁军李莎莎王来贵辽宁工程技术大学安全科学与工程学院阜新123000 矿山热动力灾害与防治教育部重点实验室阜新123000 大连交通大学辽宁省隧道与地下结构工程技术研究中心大连116028 辽宁工程技术大学力学与工程学院阜新123000

考虑完备或不完备背景关系中蕴含的元件与系统功能结构关系,提出了基于因素空间理论中因素逻辑的系统功能结构分析法,给出了该方法的严谨的数学定义系统及分析过程的逻辑数学描述。对完备和不完备两个例子进行分析后得到了两个不同的系... 详细信息

考虑完备或不完备背景关系中蕴含的元件与系统功能结构关系,提出了基于因素空间理论中因素逻辑的系统功能结构分析法,给出了该方法的严谨的数学定义系统及分析过程的逻辑数学描述。对完备和不完备两个例子进行分析后得到了两个不同的系统功能结构表达式,说明完备背景关系可得到唯一确定的系统功能结构,不完备背景关系可以得到一族确定的系统功能结构。如果不完备背景关系是完备背景关系的子集,那么在不完备背景关系中一定能找到功能之间的线性关系,以补充不完备背景关系。该方法是严谨的逻辑数学推理,可用于广泛领域类似问题的分析。

关键词：因素空间因素逻辑空间故障树系统功能结构背景关系

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食品微生物快速检测技术的研究进展

生命科学仪器 2009年第10期7卷 60-63页

作者：王莎莎西华大学生物工程学院四川成都610039

随着食品安全问题越来越受到人们关注,食品微生物的快速检测显得尤为重要,本文主要介绍了食品快速检测方法的发展历程,以及近年来最新的食品的快速检测方法。

关键词：食品微生物快速检测技术酶联免疫法生物感应器

Effectiveness of mobile health interventions on management of patients with hypertension: a systematic review of systematic reviews

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Frontiers of Nursing 2025年第01期 1-12页

作者： Si-Si Wu Xue-Mei Tu Gui-Qin Mou Chun-Hua Long sha-sha Li Department of Cardiovascular Medicine Chongqing University Three Gorges Hospital

Objective: To systematically evaluate the effectiveness of mobile health(m Health) interventions on self-management and blood pressure(BP) control in patients with hyper tension and to provide recommendations for the clinic and future ***: Databases including Embase, Cochrane Library, CINAHL, CNKI, Sino Med, Wanfang, and Weipu were searched to collect systematic reviews(SRs) and meta-analyses on m Health interventions for hyper tension management. Two researchers independently screened the ar ticles and extracted data, and the Assessment of Multiple Systematic Reviews(AMSTAR 2) was used to evaluate the methodological quality of the included ***: A total of 11 SRs were included: 1 review was rated as high quality, 3 as low quality, and 7 as critically low quality. The mobile phone was the most common intervention type, followed by the internet. Seven reviews performed meta-analyses and showed that m Health was associated with a significant reduction in systolic blood pressure(SBP), from 2.28 mm Hg(95%CI –3.90 to –0.66; I2 = 40%) to 14.77 mm Hg(95%CI 11.76–17.77; I2 = 89.7%), and diastolic blood pressure(DBP), from 1.50 mm Hg(95%CI –2.20 to –0.08; I2 = 62%) to 8.17 mm Hg(95%CI 5.67–10.67; I2 = 86%). Self-management behaviors included medication adherence(MA), diet, smoking, alcohol drinking, physical activity, and BP monitoring. There were inconsistent results on the effectiveness of m Health ***: m Health interventions can improve BP control, MA, diet, and smoking in patients with hyper tension, but the evidence for the efficacy of m Health on physical activity and alcohol drinking improvement is limited. The methodological quality of existing SRs on the management of BP in patients with hyper tension was relatively low, and more well-designed SRs or meta-analyses were needed to provide more evidence. m Health interventions are useful for improving BP control of patients with hyper tension.

关键词：

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Effectiveness of mobile health interventions on management of patients with hypertension:a systematic review of systematic reviews

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Frontiers of Nursing 2025年第1期12卷 1-12页

作者： Si-Si Wu Xue-Mei Tu Gui-Qin Mou Chun-Hua Long sha-sha Li Department of Cardiovascular Medicine Chongqing University Three Gorges HospitalChongqing 404020China

Objective:To systematically evaluate the effectiveness of mobile health(mHealth)interventions on self-management and blood pressure(BP)control in patients with hypertension and to provide recommendations for the clinic and future ***:Databases including Embase,Cochrane Library,CINAHL,CNKI,SinoMed,Wanfang,and Weipu were searched to collect systematic reviews(SRs)and meta-analyses on mHealth interventions for hypertension *** researchers independently screened the articles and extracted data,and the Assessment of Multiple Systematic Reviews(AMSTAR 2)was used to evaluate the methodological quality of the included ***:A total of 11 SRs were included:1 review was rated as high quality,3 as low quality,and 7 as critically low *** mobile phone was the most common intervention type,followed by the *** reviews performed meta-analyses and showed that mHealth was associated with a significant reduction in systolic blood pressure(SBP),from 2.28 mmHg(95%CI-3.90 to-0.66;I^(2)=40%)to 14.77 mmHg(95%CI 11.76-17.77;I^(2)=89.7%),and diastolic blood pressure(DBP),from 1.50 mmHg(95%CI-2.20 to-0.08;I^(2)=62%)to 8.17 mmHg(95%CI 5.67-10.67;I^(2)=86%).Self-management behaviors included medication adherence(MA),diet,smoking,alcohol drinking,physical activity,and BP *** were inconsistent results on the effectiveness of mHealth ***:mHealth interventions can improve BP control,MA,diet,and smoking in patients with hypertension,but the evidence for the efficacy of mHealth on physical activity and alcohol drinking improvement is *** methodological quality of existing SRs on the management of BP in patients with hypertension was relatively low,and more well-designed SRs or meta-analyses were needed to provide more *** interventions are useful for improving BP control of patients with hypertension.

关键词： blood pressure hypertension mobile health self-management smartphone systematic review

慢性情绪应激对急性心肌梗死后骨髓c-kit~＋干细胞动员的影响

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中国循环杂志 2018年第7期33卷 709-713页

作者：王超杜泓森侯季秋燕莎莎王昀赵海滨北京中医药大学第三附属医院北京市100029 北京中医药大学北京中医医院顺义医院北京中医药大学东方医院

目的:探讨慢性情绪应激(焦虑和抑郁)对急性心肌梗死后骨髓c-kit+干细胞动员的影响。方法:根据随机数字表将SD大鼠分为假手术组、心肌梗死组、心肌梗死合并焦虑组、心肌梗死合并抑郁组,每组6只。采用两种慢性情绪应激方案,分别建立焦虑... 详细信息

目的:探讨慢性情绪应激(焦虑和抑郁)对急性心肌梗死后骨髓c-kit+干细胞动员的影响。方法:根据随机数字表将SD大鼠分为假手术组、心肌梗死组、心肌梗死合并焦虑组、心肌梗死合并抑郁组,每组6只。采用两种慢性情绪应激方案,分别建立焦虑和抑郁的慢性情绪应激模型,并与冠状动脉左前降支结扎建立心肌梗死模型相结合,分别建立心肌梗死合并焦虑、心肌梗死合并抑郁的大鼠模型。超声心动图评价大鼠心功能,旷野试验评价大鼠活动能力,高架十字迷宫评价大鼠焦虑状态,强迫游泳评价大鼠抑郁状态,HE染色观察心脏和大脑病理改变,Masson染色观察心肌纤维化程度,酶联免疫吸附法(ELISA)检测外周血核转录因子-κB(NF-κB)的表达,流式细胞术检测外周血和骨髓c-kit^+干细胞的阳性细胞数。结果:(1)心肌梗死组、心肌梗死合并焦虑组、心肌梗死合并抑郁组的左心室射血分数低于假手术组,心肌梗死合并焦虑组和心肌梗死合并抑郁组的左心室射血分数低于心肌梗死组,差异均有统计学意义(P均<0.05)。(2)相比于心肌梗死组,心肌梗死合并焦虑组大鼠倾向于停留在高架十字迷宫中闭合臂,心肌梗死合并抑郁组的大鼠强迫游泳试验中漂浮不动的时间延长,且两组大鼠在旷野试验中的运动能力均减弱(P均<0.05)。(3)病理染色结果显示,心肌梗死组、心肌梗死合并焦虑组和心肌梗死合并抑郁组大鼠的心肌出现心肌坏死和纤维化,心肌梗死合并焦虑组和心肌梗死合并抑郁组大鼠的大脑海马CA3区细胞排列紊乱。(4)心肌梗死合并焦虑组和心肌梗死合并抑郁组的大鼠外周血NF-κB含量高于心肌梗死组(P<0.05)。相比于心肌梗死组,心肌梗死合并焦虑组大鼠骨髓c-kit^+干细胞数减少,心肌梗死合并抑郁组大鼠外周血c-kit^+干细胞数减少(P均<0.05)。结论:结扎冠状动脉左前降支联合空瓶刺激法、孤养+慢性不可预知性刺激分别可建立心肌梗死合并焦虑大鼠模型、心肌梗死合并抑郁大鼠模型;焦虑和抑郁可抑制心肌梗死后骨髓和外周血c-kit^+干细胞的动员,其原因可能与焦虑抑郁导致心肌梗死后NF-κB升高有关。

关键词：急性心肌梗死焦虑抑郁骨髓干细胞