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Preparation and Application of Polymyxin B Affinity Membrane Cartridge

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Chinese Chemical Letters 1997年第8期8卷 745-746页

作者： Guo, W shang, zh.yu, yn zhou, LM zhou, K CHINESE ACAD SCI DALIAN INST CHEM PHYSDALIAN 116012PEOPLES R CHINA shangHAI MED UNIV ZHONGSHAN HOSPSHANGHAI 200032PEOPLES R CHINA

Affinity membrane was used for the endotoxin adsorption. The matrix macropore membrane was prepared from filterpaper by chemically crosslinking, and polymyxin B was immobilized as affinity ligand. The prepared membrane cartridge can be used for the removal of endotoxin from aqueous solutions. With a cartridge of 40 sheets affinity membrane containing, the endotoxin level of the processed solution can be reduced to a minimum of 4 pg/mL.

关键词： REMOVAL

ENDOTOXIN REMOVAL BY MEMBRANE AFFINITY CHROMATOGRAPHY

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Chinese Chemical Letters 1995年第10期6卷 919-922页

作者： Guo, W shang, zh.yu, yn zhou, LM Zun, ZY Ma, LR Chen, MY Chinese Acad Sci Dalian Inst Chem Phys Dalian 116012 Peoples R China Acad Mil Med Sci Inst Radiat Med Beijing 100850 Peoples R China

Endotoxin was removed by membrane affinity chromatography. Macropore cellulose membrane was prepared from filter paper by alkaline treatment and chemical crosslinking, and was used as stationary phase for affinity chromatography. The matrix membrane was derived by hexamethylenediamine and activated by glutaraldehyde before histidine was immobilized as affinity ligand. A membrane cartridge containing 40 sheets of affinity membrane was also prepared, which can be used to remove pyrogen from aqueous solutions.

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Generating Baikal-GVD high energy cascade-like neutrino events with a GEANT4-based simulation toolkit

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Chinese Physics C 2024年第10期48卷 256-263页

作者： Zike Wang A.D.Avrorin zhen Cao Mingjun Chen Peiyuan Chu zh.-A.M.Dzhilkibaev Bo Gao Tianqi Huang Jiali Liu Ying Qi Xiaohao You D.N.Zaborov Key Laboratory of Particle Astrophysics Experimental Physics Division&Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China Institute for Nuclear Research of the Russian Academy of Sciences Moscow 117312Russia TIANFU Cosmic Ray Research Center Chengdu 610213China School of Science Tibet UniversityLhasa 850000China

Using the GEANT4 and Cosmic Ray Monte Carlo(CRMC)software packages,we developed a new simulation toolkit for astrophysical neutrino *** configuring the Baikal-GVD detector and comparing the vertex position and direction of incident particles,as well as the channel-by-channel signals,to the events detected by Baikal-GVD,we successfully generated 13 high-energy cascade neutrino events with the *** analysis revealed a systematic offset between the reconstructed shower position and the true interaction position,with a distance close to the scale of the shower maximum of−0.54±1.29 *** achieved a good linear relationship between the photoelectron number of neutrino events obtained by simulation and the real data measured by *** simulation toolkit could serve as a reliable basis for studying the performance of astrophysical neutrino telescopes.

关键词： high-energy neutrino cascade event simulation Cherenkov

Multi-objective optimization of a high speed on/off valve for dynamic performance improvement and volume minimization

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Chinese Journal of Aeronautics 2024年第10期37卷 435-444页

作者： Qi zhONG Junxian WANG Enguang XU Cheng yu Yanbiao LI College of Mechanical Engineering Zhejiang University of TechnologyHangzhou 310023China Key Laboratory of Special Purpose Equipment and Advanced Processing Technology Ministry of Education and Zhejiang ProvinceZhejiang University of TechnologyHangzhou 310023China

Hydraulic circuits with high speed on/off valve(HSV)for servo control have become commonplace in ***,the individual valve that is not volume-optimized results in a large total size of hydraulic control system,diminishing the *** address this issue,the high-precision equivalent reluctance model of the HSV is established by employing an equivalent magnetic circuit,on which the dynamic characteristic of the HSV,as well as the effects of structural parameters on switching behaviour,are *** on this model,multi-objective optimization is adopted to design an HSV with faster dynamic performance and smaller volume,NSGA-II genetic algorithm is applied to obtain the Pareto front of the desired *** assess the impact before and after optimization,an HSV based on the optimized structure is manufactured and *** experimental results show that the optimized HSV reduces 47.1%of its solenoid volume while improving opening and closing dynamic performance by 14.8%and 43.0%respectively,increasing maximum switching frequency by 6.2%,and expanding flow linear control area by 6.7%.These results validate the optimized structure and indicate that the optimization method provided in the paper is beneficial for developing superior HSV.

关键词： High speed on/off valve Dynamic response Volume Multiobjective optimization NSGA-II genetic algorithm

AN EXACT ANALYSIS OF THERMAL BUCKLING OF PIEZOELECTRIC LAMINATED PLATES

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Acta Mechanica Solida Sinica 1997年第2期10卷 95-107页

作者： shang, FL Wang, ZK Li, zh XIAN JIAOTONG UNIV DEPT ENGN MECHXIAN 710049PEOPLES R CHINA

In this paper, the governing differential equations of elastic stability problems in thermopiezoelectric media are deduced. The solutions of the thermal buckling problems for piezoelectric laminated plates are presented in the context of the mathematical theory of elasticity. Owing to the complexity of the eigenvalue problem involved, the critical temperature values of thermal buckling must be solved numerically. The numerical results for piezoelectric/non-piezoelectric laminated plates are presented and the influence of piezoelectricity upon thermal buckling temperature is discussed.

关键词： thermopiezoelectric media laminated plates thermal buckling

A Simple and Novel Ipso-Bromination of 1-Bromomethyl-4-t-butyl-2,6-dimethylbenzene

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Chinese Chemical Letters 1997年第4期8卷 271-274页

作者： zhang, WC yu, zh CHINESE ACAD SCI INST CHEMBEIJING 100080PEOPLES R CHINA

A novel ipso electrophlic substitution of 1-bromomethyl-4-t-butyl-2,6-dimethylbenzene 1 with nitric acid in alcohol, which gives ipso-bromination product of 1-bromo-4-t-butyl-2,6-dimethylbenzene 2, is described and a ... 详细信息

关键词： NITRATION

A review of covalent organic frameworks for metal ion fluorescence sensing

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Chinese Chemical Letters 2024年第8期35卷 74-83页

作者： Deshuai zhen Chunlin Liu Qiuhui Deng Shaoqi zhang Ningman yuan Le Li yu Liu Hunan Key Laboratory of Typical Environment Pollution and Health Hazards School of Public HealthHengyang Medical SchoolUniversity of South ChinaHengyang 421001China State Key Laboratory of Chemo/Biosensing and Chemometrics School of Chemistry and Chemical EngineeringHunan UniversityChangsha 410082China

The concentration of metallic elements is closely associated with overall ***,the discharge of untreated industrial wastewater can lead to metal-containing pollutants entering the human body through the food chain,disrupting the organism’s homeostasis and posing a risk to human ***-valent organic framework materials(COFs)have emerged as a novel porous material for detecting or adsorbing metal ions due to their unique pore structure,topological structure and flexible *** paper summarizes the role,toxicity,and sources of metal ions related to human health,as well as the design,synthesis and performance of COFs fluorescent materials for detecting these *** inter-action mechanism of different fluorescent COFs and metal ions are ***,the remaining challenges and prospects of COFs fluorescence sensors are *** believe this review will be useful in directing the development of fluorescent COFs towards metal ions.

关键词： Covalent organic frameworks Metal ion Fluorescence Sensing Toxicity

Analytical solution for tunnelling-induced response of an overlying pipeline considering gap formation

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Underground Space 2024年第2期15卷 298-311页

作者： Cungang Lin Junjie zheng Yiwen Ye Farrokh Nadim zhongqiang Liu Chenyang zhao yu Chen zhi Ding Guangdong Research Center for Underground Space Exploitation Technology School of Civil EngineeringSun Yat-sen UniversityGuangzhou 510275China Guangdong Key Laboratory of Marine Civil Engineering School of Civil EngineeringSun Yat-sen UniversityGuangzhou 510275China State Key Laboratory for Tunnel Engineering Ministry of EducationGuangzhou 510275China Southern Marine Science and Engineering Guangdong Laboratory(zhuhai) Zhuhai 519082China School of Civil Engineering Wuhan UniversityWuhan 430072China Guangdong Road and Bridge Construction Development Co. Ltd.Guangzhou 510660China Norwegian Geotechnical Institute Oslo 0806Norway Key Laboratory of Safe Construction and Intelligent Maintenance for Urban Shield Tunnels of zhejiang Province Hangzhou 310015China

Soil-pipeline separation due to tunnelling has been certainly substantiated in previous model ***,this phenomenon has seldom been considered in current analytical *** study formulates a tensionless Winkler solution that could make allowance for gap formation in soil-pipeline interaction *** solution is validated by comparisons with existing experimental measurements and two recognized analytical ***,its advantage over an existing Winkler solution is *** parametric studies reveal that the effects of gap formation on the response of a pipeline rely largely on the tunnel volume loss and the pipeline’s bending stiffness and burial *** general,a pipeline’s bending moments and subgrade reaction forces are more susceptible than its deflections to the gap formation.

关键词： Soil-pipeline interaction Tunnelling Tensionless Winkler model Ground settlement Analytical solution Gap formation

Endoscopic dacryocystorhinostomy in acute dacryocystitis:a multicenter study in China

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International Journal of Ophthalmology(English edition) 2024年第9期17卷 1689-1695页

作者： Bang-Xun Mao Yao-Hua Wang zhen-Kai Liu Ning-yu An Hai-Li Jin Ming-Ling Wang Wen-Can Wu Bo yu Department of Ophthalmology Central Hospital of LishuiThe Fifth Affiliated Hospital of Wenzhou Medical UniversityLishui 323000Zhejiang ProvinceChina Department of Orbital Disease and Ophthalmic Tumor Affiliated Eye Hospital of Nanchang UniversityNanchang 330000Jiangxi ProvinceChina Department of Ophthalmology Renmin Hospital of ShiyanShiyan 442000Hubei ProvinceChina Eye Hospital of Ningxia Yinchuan 750000Ningxia Hui Autonomous RegionChina Eye Hospital of Wuhu City Wuhu 241000Anhui ProvinceChina Department of Ophthalmology Baoan Central Hospital of ShenzhenShenzhen 518000Guangdong ProvinceChina Department of Orbital and Oculoplastic Surgery Eye Hospital of Wenzhou Medical UniversityWenzhou 325000Zhejiang ProvinceChina

AIM:To repor t the clinical profile,endoscopic dacryocystorhinostomy(En-DCR)management,and acute dacryocystitis(AD)outcomes in ***:Clinical data of 554 adult AD patients(554 eyes)who presented in 7 tertiary eye care centers for 10y from Jan 2010 to Mar 2020 were retrospectively *** profile,En-DCR management,and outcomes of all cases were *** anatomical and functional success were evaluated for 12mo ***:The analysis included 149 males and 368 females with a median age of 55.2y(range:18-84y).There were 459 eyes with a history of epiphora or purulent *** time between a symptom of lacrimal duct obstruction and acute onset was 1 to 540(66.1±58.2)***-nine eyes had a history of the previous acute ***-four eyes developed a cutaneous fistula,while 11 eyes had post septal cellulitis ***-DCR with an anatomical success of 91.7%and functional success of 90.1%.The success rate of the patients with a history of acute episodes and the preoperative fistula was lower than the overall success ***:En-DCR can be performed during an acute episode in AD with a success rate of over 90%.

关键词： acute dacryocystitis endoscopic dacryocystorhinostomy lacrimal sac