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Neural Regeneration Research 2024年第10期19卷 2097-2098页

作者： Antara Verma Stephen k.Agadagba Leanne lai-Hang Chan Department of Electrical Engineering City University of Hong KongKowloonHong Kong Special Administrative RegionChina Centre for Eye and Vision Research Ltd. Hong Kong Special Administrative RegionChina Pennsylvania State University University ParkPAUSA

The connection and interaction between the eye and the brain are crucial to understanding brain disorders(Marchesi et al.,2021).Both the eye and the brain have a limited regenerative capacity as there are few progenitor cells,and nerve cells do not ***,neurodegeneration implicates irreversible damage to the central nervous system,as observed in several neurodegenerative diseases(Marchesi et al.,2021).

关键词： stimulation degenerative

On the role of sliding friction effect in nonlinear tri-hybrid vibration-based energy harvesting

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Applied Mathematics and Mechanics(English Edition) 2024年第8期45卷 1295-1314页

作者： Jiamei wang Siuk.i lai Chen wang Yiting ZHANG Zhaolin CHEN Department of Civil and Environmental Engineering The Hong Kong Polytechnic UniversityHong KongChina The Hong k.ng Polytechnic University shenzhen Research Institute Shenzhen 518057Guangdong ProvinceChina Hebei k.y Laboratory of Mechanical Reliability for Heavy Equipments and Large Structures Yanshan UniversityQinghuangdao 066000Hebei ProvinceChina School of Aeronautics Northwestern Polytechnical UniversityXi'an 710072China

This work.aims to develop an experimental investigation into the effectiveness of the sliding-mode approach for hybrid vibration-based energy harvesting.A proposed sliding-mode triboelectric-electromagnetic-piezoelectric energy harvesting model involves a cantilever beam with a tip mass exposed to magnetic and frictional *** experimental findings indicate that the system can achieve its peak.inter-well oscillation output within a low-frequency range of 4 Hz–6 *** has a lesser impact on the open-circuit voltage output at an excitation acceleration of 1.5g compared with *** distribution of tri-stability changes with the presence of *** model provides a deeper understanding of the influence of the dry friction coefficient(0.2–0.5) on the interactive behaviors of different generator units.

关键词： sliding mode tri-hybrid energy harvesting friction nonlinear behavior

Optimal Strategy for Aircraft Pursuit-evasion Games via Self-play Iteration

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Machine Intelligence Research 2024年第3期21卷 585-596页

作者： Xin wang Qing-lai Wei Tao Li Jie Zhang State k.y Laboratory of Management and Control for Complex Systems Institute of AutomationChinese Academy of SciencesBeijing100190China School of Artificial Intelligence University of Chinese Academy of SciencesBeijing100049China Institute of Systems Engineering Macao University of Science and TechnologyMacao999078China

In this paper,the pursuit-evasion game with state and control constraints is solved to achieve the Nash equilibrium of both the pursuer and the evader with an iterative self-play *** the condition where the Hamiltonian formed by means of Pontryagin’s maximum principle has the unique solution,it can be proven that the iterative control law converges to the Nash equilibrium ***,the strong nonlinearity of the ordinary differential equations formulated by Pontryagin’s maximum principle mak.s the control policy difficult to figured *** the system dynamics employed in this manuscript contains a high dimensional state vector with *** practical applications,such as the control of aircraft,the provided overload is ***,in this paper,we consider the optimal strategy of pursuit-evasion games with constant constraint on the control,while some state vectors are restricted by the function of the *** address the challenges,the optimal control problems are transformed into nonlinear programming problems through the direct collocation ***,two numerical cases of the aircraft pursuit-evasion scenario are given to demonstrate the effectiveness of the presented method to obtain the optimal control of both the pursuer and the evader.

关键词： Differential games pursuit-evasion games nonlinear control optimal control Nash equilibrium solution

Cr-catalyzed allylic C(sp^(3))–H addition to aldehydes enabled by photoinduced ligand-to-metal charge transfer

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Science China Chemistry 2024年第5期67卷 1589-1595页

作者： Xianrong Zeng Feng-Hua Zhang Runchen lai Xiaoyu Lin Zhaobin wang k.y Laboratory of Precise Synthesis of Functional Molecules of Zhejiang Province Department of ChemistrySchool of Science and Research Center for Industries of the FutureWestlake UniversityHangzhou 310030China Institute of Natural Sciences Westlake Institute for Advanced StudyHangzhou 310024China k.y Laboratory of Precise Synthesis of Functional Molecules of Zhejiang Province Instrumentation and Service Center for Molecular SciencesWestlake UniversityHangzhou 310024China

Photoinduced ligand-to-metal charge transfer(LMCT) has emerged as an effective strategy for synthesizing organic molecules in a sustainable manner. However, the majority of existing reports on selective C(sp^(3))–H bond functionalization via photoinduced LMCT focus on the use of late transition metals or rare-earth metals for radical additions or cross-couplings. In contrast, the utilization of photoinduced LMCT with 3d early transition metals poses a significant challenge. Herein, we describe an unprecedented approach to allylic C(sp^(3))–H addition to aldehydes, employing chromium(Cr) complexes as catalysts through visible-light-induced LMCT. By investigating the reaction pathway through various mechanistic studies, including radical trapping, k.netic isotope effect(k.E) analysis, and transient absorption spectroscopy, valuable insights have been gained. The proposed mechanism suggests the intermediacy of bromine radicals through homolysis of the Cr–Br bond. Notably, this protocol expands our understanding of the photochemical properties of earth-abundant Cr complexes.

关键词： Cr catalysis photoinduced ligand-to-metal charge transfer hydrogen-atom transfer carbonyl addition

Adrenal pheochromocytoma impacts three main pathways: cysteine-methionine, pyrimidine, and tyrosine metabolism

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2024年第5期25卷 410-421页

作者： Chong lai Qingling YANG Yunuo ZHANG Renjie GONG Majie wang Jiank.ng LI Maode lai Qingrong SUN Department of Urology the First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China School of Basic Medical Sciences and Clinical Pharmacy China Pharmaceutical UniversityNanjing 210009China Department of Laboratory Medicine the First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China Laboratory of Behavioral Neuroscience Ningbo Kangning HospitalNingbo Institute of Microcirculation and HenbaneSchool of MedicineNingbo UniversityNingbo 315201China Xi'an k.y Laboratory of Stem Celland Regenerative Medicine Institute of Medical ResearchNorthwestern Polytechnical UniversityXi'an 710072China Department of Pathology Research Unit of Intelligence Classification of Tumor Pathology and Precision TherapyChinese Academy of Medical Sciences Key Laboratory of Disease Proteomics of Zhejiang ProvinceZhejiang University School of MedicineHangzhou 310058China

Pheochromocytomas and paragangliomas(PPGLs)cause symptoms by altering the circulation levels of catecholamines and peptide ***,the diagnosis of PPGLs relies on diagnostic imaging and the detection of *** this study,we used ultra-performance liquid chromatography(UPLC)/quadrupole time-of-flight mass spectrometry(Q-TOF MS)analysis to identify and measure the perioperative differential metabolites in the plasma of adrenal pheochromocytoma *** identified differentially expressed genes by comparing the transcriptomic data of pheochromocytoma with the normal adrenal *** conducting two steps of metabolomics analysis,we identified 111 differential metabolites between the healthy group and the patient group,among which 53 metabolites were *** integrating the information of differential metabolites and differentially expressed genes,we inferred that the cysteine-methionine,pyrimidine,and tyrosine metabolism pathways were the three main metabolic pathways altered by the *** analysis of transcription levels revealed that the tyrosine and cysteine-methionine metabolism pathways were downregulated in pheochromocytoma,whereas the pyrimidine pathway showed no significant ***,we developed an optimized diagnostic model of two metabolites,L-dihydroorotic acid and *** results for these metabolites suggest that they may serve as potential clinical biomark.rs and can be used to supplement and improve the diagnosis of pheochromocytoma.

关键词： Pheochromocytoma and paraganglioma(PPGL) Metabolomics Gene set variation analysis L-Dihydroorotic acid Vanylglycol

Oils with different degree of saturation:effects on ileal digestibility of fat and corresponding additivity and bacterial community in growing pigs

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Journal of Animal Science and Biotechnology 2024年第4期15卷 1657-1668页

作者： Lu wang Yifan Chen Yuansen Yang Nuo Xiao Changhua lai State k.y Laboratory of Animal Nutrition Ministry of Agriculture and Rural Affairs Feed Industry CentreChina Agricultural UniversityNo.2 Yuanmingyuan West RoadHaidian DistrictBeijing 100193China College of Animal Science and Technology Hebei Agricultural UniversityHebei 071000China

Back.round Oils are important sources of energy in pig *** combination of oils with different degree of saturation contributes to improve the utilization efficiency of the mixed oils and may reduce the cost of oil *** experiment was conducted to evaluate the effects of oils with different degree of saturation on the fat digestibility and corresponding additivity and bacterial community in growing *** Eighteen crossbred(Duroc×Landrace×York.0}ire)barrows(initial body weight:29.3±2.8 k.)were surgically fitted with a T-cannula in the distal *** experimental diets included a fat-free basal diet and 5 oil-added *** 5 oil-added diets were formulated by adding 6%oil with different ratio of unsaturated to saturated fatty acids(U:S)to the basal *** 5 oils were palm oil(U:S=1.2),canola oil(U:S=12.0),and palm oil and canola oil were mixed in different proportions to prepare a combination of U:S of 2.5,3.5 and 4.5,*** The apparent and standardized ileal digestibility(AID and SID)of fat and fatty acids increased linearly(Pk.n-line analyses for the SID of fat,saturated fatty acids(SFA)and UFA indicated that the break.oint for U:S of oil was 4.14(R^(2)=0.89,P<0.01),2.91(R^(2)=0.98,P<0.01)and 3.84(R^(2)=0.85,P<0.01),*** determined SID of fat,C18:1,C18:2 and UFA in the mixtures was not different from the calculated SID of fat,C18:1,C18:2 and ***,the determined SID of C16:0,C18:0 and SFA in the mixtures were greater than the calculated SID values(P<0.05).The abundance of Romboutsia and Turicibacter in pigs fed diet containing palm oil was greater than that in rapeseed oil treatment group,and the two bacteria were negatively correlated with SID of C16:0,C18:0 and SFA(P<0.05).

关键词： Additivity Bacterial community Fat and fatty acids Growing pigs Ratio of unsaturated to saturated fatty acids Standardized ileal digestibility

Preheating-assisted solid-state friction stir repair of Al-Mg-Si alloy plate at different rotational speeds

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International Journal of Minerals,Metallurgy and Materials 2024年第4期31卷 725-736页

作者： Hui wang Yidi Li Ming Zhang Wei Gong Ruilin lai Yunping Li State k.y Laboratory of Powder Metallurgy Central South UniversityChangsha 410083China Research Institute of Light Alloy Central South UniversityChangsha 410083China

Additive friction stir deposition(AFSD)is a novel structural repair and manufacturing technology has become a research hotspot at home and abroad in the past five *** this work.the microstructural evolution and mechanical performance of the Al-Mg-Si alloy plate repaired by the preheating-assisted AFSD process were *** evaluate the tool rotation speed and substrate preheating for repair quality,the AFSD technique was used to additively repair 5 mm depth blind holes on 6061 aluminum alloy *** results showed that preheat-assisted AFSD repair significantly improved joint bonding and joint strength compared to the control non-preheat substrate ***,increasing rotation speed was also beneficial to improve the metallurgical bonding of the interface and avoid volume *** preheating conditions,the UTS and elongation were positively correlated with rotation *** the process parameters of preheated substrate and tool rotation speed of 1000 r/min,defect-free specimens could be obtained accompanied by tensile fracture occurring in the substrate rather than the repaired *** UTS and elongation reached the maximum values of 164.2MPa and 13.4%,which are equivalent to 99.4%and 140%of the heated substrate,respectively.

关键词： additive friction stir deposition structural repair tool rotation speed Al alloy

In-situ coating and surface partial protonation co-promoting performance of single-crystal nick.l-rich cathode in all-solid-state batteries

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Journal of Energy Chemistry 2024年第2期89卷 137-143,I0005页

作者： Maoyi Yi Jie Li Mengran wang Xinming Fan Bo Hong Zhian Zhang Aonan wang Yanqing lai School of Metallurgy and Environment Central South UniversityChangsha 410083HunanChina Engineering Research Centre of Advanced Battery Materials The Ministry of EducationChangsha 410083HunanChina Hunan Province k.y Laboratory of Nonferrous Value-Added Metallurgy Central South UniversityChangsha 410083HunanChina

The poor electrochemical performance of all-solid-state batteries(ASSBs),which is assemblied by Ni-rich cathode and poly(ethylene oxide)(PEO)-based electrolytes,can be attributed to unstable cathodic interface and poor crystal structure stability of Ni-rich *** coating strategies are previously employed to enhance the stability of the cathodic interface and crystal structure for Ni-rich ***,these methods can hardly achieve simplicity and high efficiency *** this work.polyacrylic acid(PAA)replaced traditional PVDF as a binder for cathode,which can achieve a uniform PAA-Li(LixPAA(0k.provides a practical strategy to construct high-performance cathodes for ASSBs.

关键词： Single-crystal LiNi_(0.83)Co_(0.12)Mn_(0.05)O_(2) In-situ coating PAA-Li Partial protonation

In Situ Coupling of Highly Dispersed Ni/Fe Metal-NC Sites and N-Doped 3D Carbon Fibers Toward Free-Standing Bifunctional Cathode for Flexible Zinc-Air Battery

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Energy & Environmental Materials 2024年第1期7卷 121-130页

作者： Chenglong lai Mengjun Li Yi shen Min Zhou Wei wang k.i Jiang Haomiao Li k.ngli wang State k.y Laboratory of Advanced Electromagnetic Engineering and Technology School of Electrical and Electronic EngineeringHuazhong University of Science and TechnologyWuhan 430074China School of Materials Science and Engineering Huazhong University of Science and TechnologyWuhanHubei 430074China Engineering Research Center of Power Safety and Efficiency Ministry of EducationWuhanHubei 430074China

Designing flexible free-standing air-electrode with efficient OER/ORR performance is of vital importance for the application of Zinc-air batteries in flexible ***,a flexible free-standing electrode(Ni/Fe-NC/NCF/CC)is synthesized by in-situ coupling of binary Ni/Fe-NC nanocubes and N-doped carbon nanofibers(NCF)rooted on carbon *** highly dispersed binary Ni/Fe-NC sites ensure excellent ORR activity and create efficient OER active sites relative to Ni-NC and *** in-situ coupling of Ni/Fe-NC and NCF constructs a 3D interconnected network.structure that not only provides abundant and stabilized reactive sites but also guarantees fast electron transfer and gas transportation,thus achieving efficient and fast operation of ORR/***,Ni/Fe-NC/NCF/CC displays a much positive potential(0.952 V)at 4.0 mA cm^(-2)for ORR and a low OER overpotential(310 mV)at 50 mA cm^(-2).The Zinc-air battery with Ni/Fe-NC/NCF/CC air-electrode exhibits excellent battery performance with outstanding discharge/charge durability for 2150 *** flexible Zn-air batteries with foldable mechanical properties display a high power density of 105.0 mW cm^(-2).This work.widened the way to prepare flexible bifunctional air-electrode by designing composition/structure and in-situ coupling.

关键词： binary Ni/Fe-NC sites in-situ coupling synergistic catalytic effect Zn-air battery

Realization of Low in-Band Harmonic for Compact 6–18-GHz T/R Module Under TX-Mode Operation

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Chinese Journal of Electronics 2024年第2期33卷 380-384页

作者： Jinming lai Zhiyou LI Chaojie wang Hailong wang Xiaohua MA School of Microelectronics Xidian University CETC 29th Research Institute

Wideband high power amplifier(PA) with poor harmonic suppression will degrade the performance of the active electronically scanned array(AESA) due to its harmonic products falling into the operating bandwidth of a wideband T/R module. In view of this, a compact reconfigurable harmonic suppress circuit(HSC) is proposed to achieve low in-band harmonic for compact T/R module with multiple octaves under TX-mode operation. The HSC consists of eight microstrip resonant stubs with high impedance and multiple p-i-n switches. By controlling the p-i-n switches, the HSC can work.in three states. When six of the used p-i-n switches are “ON” state, the corresponding microstrip resonant stubs are loaded onto the 50 Ω transmission line, which performs a bandstop filter(BSF). For verification, the HSC with bandwidth of 12–15 GHz/15–18 GHz is designed to apply to a 6–18 GHz T/R module. As a result, the second harmonic of 6–9 GHz transmitting signal can be suppressed below 32 d Bc when compared to the PA's fundamental output. While the p-i-n switches are “OFF” state, the HSC is almost the same as a 50 Ω transmission line, which will have a little effect on the 9–18 GHz transmitting signal. The measurement results approximately agree with the calculated results and simulated results, which demonstrate the validity of the proposed HSC.

关键词： Microstrip filters Harmonics suppression Power transmission lines PIN photodiodes Switches Harmonic analysis Transmission line measurements