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天津医学院学报 1991年第1期15卷 1-3页

作者：汤特 Lngb.,sh

The 16th Workshop on Antarctic Meteorology and Climate and 6th Year of Polar Prediction in the Southern hemisphere Meeting

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Advances in Atmospheric Sciences 2022年第3期39卷 536-542页

作者： David h.BROMWICh Matthew A.LAZZARA Arthur M.CAYETTE Jordan G.POWERS Kirstin WERNER John J.CASSANO Steven R.COLWELL Scott CARPENTIER Xun ZOU Byrd Polar and Climate Research Center The Ohio State UniversityColumbusOhio 43210USA Antarctic Meteorological Research Center Space Science and Engineering CenterUniversity of Wisconsin-MadisonMadisonWisconsin 53704USA Department of Physical Sciences Madison Area Technical CollegeMadisonWisconsin 53706 USA Naval Information Warfare Center CharlestonSouth Carolina 29406USA National Center for Atmospheric Research BoulderColorado 53706USA Year of Polar Prediction(YOPP)International Coordination Office Alfred Wegener InstituteHelmholtz Centre for Polar and Marine ResearchBremerhaven 27570Germany National Snow and Ice Data Center Cooperative Institute for Research in Environmental Sciences and Department of Atmospheric and Oceanic SciencesUniversity of ColoradoBoulderColorado 80309USA British Antarctic Survey Cambridge CB30ETUnited Kingdom Bureau of Meteorology Hobart 7001Australia

1. Overview In June 2021, the 16th Workshop on Antarctic Meteorology and Climate (WAMC) and the 6th Year of Polar Prediction in the Southern hemisphere (YOPP-sh) Meeting (http://***/WAMC;021/) were held online and hosted by the Polar Meteorology Group at Byrd Polar and Climate Research Center, The Ohio State University, Columbus,Ohio (Fig. 1).

关键词： Antarctic hemisphere Climate

Strengthening and deformation mechanism of high-strength CrMnFeCoNi high entropy alloy prepared by powder metallurgy

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Journal of Materials Science & Technology 2023年第1期132卷 119-131页

作者： Y.Xing C.J.Li Y.K.Mu Y.D.Jia K.K.Song J.Tan G.Wang Z.Q.Zhang J.h.Yi J.Eckert Faculty of Materials Science and Engineering Kunming University of Science and TechnologyKunming 650093China Laboratory for Microstructures Institute of MaterialsShanghai UniversityShanghai 200444China School of Mechanical Electrical&Information EngineeringShandong UniversityWeihai 264209China College of Materials Science and Engineering Chongqing UniversityChongqing 400044China Erich Schmid Institute of Materials Science Austrian Academy of SciencesJahnstraße 12Leoben A-8700Austria Department of Materials Science Chair of Materials PhysicsMontanuniversität LeobenJahnstraße 12Leoben A-8700Austria Adjunct with National University of Science and Technology«MISiS» Leninsky Prosp.4Moscow 119049Russia

Multiphase CrMnFeCoNi high-entropy alloys(hEAs)were prepared by a powder metallurgy process com-bining mechanical alloying(MA)and vacuum hot-pressing sintering(hPS).The single-phase face-centered cubic(FCC)hEA powder prepared by MA was sintered into a bulk hEA specimen containing FCC phase matrix along with precipitated M 23 C 6 phase and nanoscaleσphase *** the sintering temper-ature was 1223 K,the ultimate strength reaches 1300±11.6 MPa,and the elongation exceeds 4%±0.6%.Microstructural characterization reveals that the formation of nanoscale particles and deformation twins play critical roles in improving the strain hardening(sh)*** the MA time promoted the formation of the precipitated phase and enhanced the sh ability by increasing the number of precip-itated *** sh capacity increases significantly with increasing sintering temperature,which is attributed to a significant enhancement in the twinning capacity due to grain growth and the reduced number ofσphase *** systematic studies,the planar glide of dislocations was found to be the main mode of deformation,while deformation twinning appeared as an auxiliary deformation mode when the twinning stress was *** the formation of precipitates leads to grain bound-ary and precipitation strengthening effects,crack initiation is more prominent owing to increased grain boundary brittleness around the precipitated M 23 C 6 *** prominence of crack initiation is a contra-diction that must be reconciled with regard to precipitation *** work serves as a useful reference for the preparation of high-strength hEA parts by powder metallurgy.

关键词： high entropy alloy Powder processing Grain reﬁnement Precipitation strengthening Deformation twinning

Paeoniflorin reduces cardiotoxicity of aconitine in h9c2 cells

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中国药理学与毒理学杂志 2019年第9期33卷 689-689页

作者： LI J ZhANG sh hE D WANG JF LI JQ School of medicine University of Electronic Science and Technology of China&Department of PharmacySichuan Provincial People′s HospitalChengdu 610072China Personalized Drug Therapy Key Laboratory of Sichuan Province&Sichuan Academy of Medical Sciences Chengdu 610072China

OBJECTIVE Aconitine(ACO)as the main active component in Aconitum carmichaelii debeaux(family Ranunlaceae),has highly toxicity in heart and the mechanisms are not clear ***(PF),the main chemical ingredient in herbaceous peony,can protect heart hurt by antioxidant,vasodilator effect and other *** this study,we focused on investigating the mechanism of PF reducing the cardiotoxicity of *** We chose h9c2 cells as experimental ***,Western blotting and real-time PCR were used to measure cell proliferation,apoptosis,ion channels and oxidative *** Cell proliferation in ACO+PF group was significantly increased compared with ACO group;the ratio with Bcl-2 and Bax and the level of p53 were upregulated by PF,while the level of caspase-3 was lightly *** expression of SCN5A mRNA significantly was increased in ACO+PF group,while the expres⁃sion of RyR2 and Cx43 mRNA was *** with ACO group,extracellular LDh and intracellular MDA were highly decreased,while intracellular SOD was *** Cardiotoxicity of ACO in h9c2 cells was signifi⁃cantly decreased by PF.

关键词： acontine paeoniflorin cardiotoxicity h9c2 cell

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对甲苯磺酸催化合成硬脂酸甲酯

化学世界 2010年第9期51卷 562-564页

作者：沈之芹吴国英上海石油化工研究院油田化学品部上海201208

以对甲苯磺酸催化硬脂酸和甲醇的酯化反应,合成了硬脂酸甲酯,研究结果表明,对甲苯磺酸对酯化反应具有较高的催化活性。考察了反应时间、酸醇摩尔比、催化剂用量对酯化反应的影响。当硬脂酸与甲醇的摩尔比为1∶3.5,对甲苯磺酸用量为硬脂... 详细信息

以对甲苯磺酸催化硬脂酸和甲醇的酯化反应,合成了硬脂酸甲酯,研究结果表明,对甲苯磺酸对酯化反应具有较高的催化活性。考察了反应时间、酸醇摩尔比、催化剂用量对酯化反应的影响。当硬脂酸与甲醇的摩尔比为1∶3.5,对甲苯磺酸用量为硬脂酸质量的1.2%,于回流温度反应4 h,硬脂酸的转化率大于98.5%,产品酸值小于3.0 mg KOh/g。

关键词：酯化硬脂酸甲醇硬脂酸甲酯对甲苯磺酸

Surveys on magnetospheric plasmas based on the Double Star Project (DSP) exploration

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Science China(Technological Sciences) 2008年第10期51卷 1639-1647页

作者： C. P. ESCOUBET C. M. CARR h. RME A. FAZAKERLEY h. LAAKSO I. DANDOURAS M. DUNLOP ESA/ESTEC SCI-SH Keplerlaan 1 2200 AG Noordwijk The Netherlands Imperial College of Science Technology and Medicine London SW7 2BZ United Kingdom CESR BP4346 31028 Toulouse Cedex 4 France Mullard Space Science Laboratory Univ. College London Dorking Surrey RH5 6NT United Kingdom Imperial College of Science Technology and Medicine London SW7 2BZ United Kingdom Rutherford Appleton Laboratory Didcot Oxon OX11 0QX United Kingdom

The equatorial and polar satellites of the Double Star Project (DSP) were launched successfully on December 29, 2003 and July 25, 2004, respectively, and both of them are operating smoothly. The DSP provides a good opportunity for investigat-ing the structure of the magnetosphere. Based on the DSP data collected during 2004, we have surveyed the distribution of the magnetic fields and plasmas in the magnetosphere. It is found that: (1) Near the Earth’s equatorial plane within geo-centric distances of less than 7 RE, the Earth’s magnetic field is dipolar. In the vi-cinity of the magnetopause, the magnetic field is enhanced by a factor of about 1.5, and on the nightside, the magnetic field can vary significantly from the Earth’s di-pole field, likely caused by the presence of the near-Earth tail current sheet. (2) In the day-side magnetosheath, the electron and ion densities are usually both in the range of 10―30 cm?3; the ion and electron temperatures are usually about 200 and 50 eV, respectively. The flow pattern is usually smooth, with a low velocity in the subsolar region and with significantly higher velocities in the dawn and dusk flanks. (3) In the region between the magnetopause and plasmasphere the density is low, approximately 0.5―5 cm?3, and the temperature is high, about 1―10 keV for ions and 0.1―5 keV for electrons. The ion temperature has an apparent anisotropy, with the ratio of the perpendicular and parallel temperatures being about 1.0―1.3 for the night- and dusk-side magnetosphere and about 1.3―2.0 for the day- and dawn-side magnetosphere. There is an evident sunward convection of about 50 km/s in the magnetosphere. On the dawn side, the flow becomes somewhat turbulent, and in the vicinity of the night-noon meridian plane, the convection is rather slow. (4) The high-energy electrons with energies higher than 2 MeV are mainly located in the regions with 3 he size of the high-energy electrons area varies with time, it may expand and shrink

关键词： Earth’s magnetosphere space exploration geomagnetic field space plasmas

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鞑靼滨藜挥发性化学成分分析

天然产物研究与开发 2010年第6期22卷 1040-1044页

作者： Janar Jenis G.sh Burasheva 阿吉艾克拜尔.艾萨巴杭 Zh.A Abilov 哈萨克斯坦国立大学化学系阿拉木图050012 中科院新疆理化技术研究所乌鲁木齐830011

对鞑靼滨藜全草的挥发性化学成分进行分析。采用水蒸气蒸馏法及索氏提取法提取鞑靼滨藜全草中的挥发性化学成分,用GC-MS联用技术分析其化学组成,计算其相对百分含量,并对两种提取方法进行比较研究。结果表明:水蒸气蒸馏法提取物的成分... 详细信息

对鞑靼滨藜全草的挥发性化学成分进行分析。采用水蒸气蒸馏法及索氏提取法提取鞑靼滨藜全草中的挥发性化学成分,用GC-MS联用技术分析其化学组成,计算其相对百分含量,并对两种提取方法进行比较研究。结果表明:水蒸气蒸馏法提取物的成分比索氏提取法较多。从水蒸气蒸馏法分离出的53个色谱峰中鉴定了51种成分,含量最高的是茴香脑(45.84%),其次为正二十七烷(9.28%),羟基吲哚(6.81%),α-羟基-2-甲基丙基苯乙酸酯(4.03%)。从索氏提取法分离出的26个色谱峰中鉴定了22种成分,含量最高的是正二十九烷(22.63%),其次为硬酯酸(16.69%),十六醛(6.89%),棕榈酸(5.43%)。

关键词：鞑靼滨藜挥发性化学成分水蒸气蒸馏法索氏提取法

PROGRESS OF SYNThETIC APERTURE SONAR IN ChINA

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PROGRESS OF SYNTHETIC APERTURE SONAR IN CHINA

弹性基础上的变厚度径向功能梯度扇形板的振动分析

2002中国—日本声学学术会议

作者： J. Tang Ch. Zhang sh. Li B. Sun J. Liu J. Xu Y. huang T. Lin sh. Xue L. Li T. Cui h. huang Y. Li Q. Li Institute of Acoustics Chinese Academy of Science 17 Zhongguancun St. Beijing PRC

The Project of synthetic aperture sonar in China started in 1997. Up to now, we have built a prototype of synthetic aperture sonar for lake trial. It is of multi elements, so it can work in high speed

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钢结构(中英文) 2010年第9期 82-82页

作者： sh.hosseini-hashemi h.Rokni Damavandi Taher h.Akhavan

在Pasternak弹性基础上,对变厚度径向功能梯度圆(环)扇形薄板进行自振分析。基于古典板理论,利用微积分方法分别求解简支和固支边界条件下的自振频率。假定薄板的径向杨氏模量和质量密度呈指数变化,泊松比恒定。研究频率的收敛性以检查... 详细信息

在Pasternak弹性基础上,对变厚度径向功能梯度圆(环)扇形薄板进行自振分析。基于古典板理论,利用微积分方法分别求解简支和固支边界条件下的自振频率。假定薄板的径向杨氏模量和质量密度呈指数变化,泊松比恒定。研究频率的收敛性以检查求解的可行性。将结果与已有文献数据对比,验证了本方法的精确性。

关键词：自由振动功能梯度扇形板变厚度弹性基础微积分方法

Epitope DNA vaccines against tuberculosis： spacers and ubiquitin modulates cellular immune responses elicited by epitope DNA vaccine

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第二军医大学学报 2005年第2期26卷 191-191页

作者： Wang QM Sun sh hu ZL Zhou FJ Yin M Xiao CJ Zhang JC Department of Medical Genetics Second Military Medical University Shanghai 200433 China

Cell-mediated immune responses are crucial in the protection against tuberculosis. In this study, we constructed epitope DNA vaccines (p3-M-38) encoding cytotoxic T lymphocyte (CTL) epitopes of MPT64 and 38 kDa proteins of Mycobacterium tuberculosis. In order to observe the influence of spacer sequence (Ala-Ala-Tyr) or ubiquitin (UbGR) on the efficacy of the two CTL epitopes, we also constructed DNA vaccines, p3-M-S(spacer)-38, p3-Ub (UbGR)-M-S-38 and p3-Ub-M-38. The immune responses elicited by the four DNA vaccines were tested in C57BL/6 (h-2b) mice. The cytotoxicity of T cells was detected by LDh-release method and by enzyme-linked immunospot assay for epitope-specific cells secreting interferon-gamma. The results showed that DNA immunization with p3-M-38 vaccine could induce epitope-specific CD8+ CTL response and that the spacer sequence (AAY) only enhanced M epitope presentation. The protein-targeting sequence (UbGR) enhanced the immunogenicity of the two epitopes. The finding that defined spacer sequences at C-terminus and protein-targeting degradation modulated the immune response of epitope string DNA vaccines will be of importance for the further development of multi-epitope DNA vaccines against tuberculosis.

关键词： DNA vaccines immune responses Mycobacterium tuberculosis cytotoxic T lymphocyte protection against DNA immunization T cells