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Ethnobotanical and traditional uses, phytochemical constituents and biological activities of Eryngium species growing in Iran

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Traditional Medicine Research 2019年第3期4卷 148-159页

作者： Masoumeh Ghajarieh Sepanlou Mehran Mirabzadeh Ardakani Mannan Hajimahmoodi Sima Sadrai Gholam-Reza Amin Naficeh Sadeghi seyedeh nargess sadati lamardi Department of Traditional Pharmacy School of Persian Medicine Tehran University of Medical Sciences Tehran Iran. Drug and Food Control Department Faculty of Pharmacy Tehran University of Medical Sciences Tehran Iran. Persian Medicine and Pharmacy Research Center Tehran University of Medical Sciences Tehran Iran. Pharmaceutical Department Faculty of Pharmacy Tehran University of Medical Sciences Tehran Iran. Pharmacognosy Department Faculty of Pharmacy Tehran University of Medical Sciences Tehran Iran.

Objective: Eryngium with the 274 accepted species, is the largest genus of Apiaceae family which are distributed all over the world and have been used in traditional remedies to manage various ailments in different nations. Ten species of Eryngium have been identified in Iran including E. caeruleum M.B.(syn: E. caucasicum Trautv.), E. creticum Lam., E. bungei Boiss., E. billardieri F. Delaroche.(syn: E. kotschyi Boiss.), E. glomeratum Lam.(syn: E. parviflorum Sm.), E. bornumulleri Nab., E. pyramidale Boiss.& Husson., E. noeanum Boiss., E. wanaturi Woron.(syn: E. woronowii Bordz.), and E. thyrsoideum Boiss. The aim of the present research is to review pharmacological activity, and phytochemical constituents as well as ethnobotany and traditional uses of Iranian species of Eryngium. Materials and methods: Electronic databases including PubMed, Scopus, Science Direct (ISI Web of Knowledge) and Embase library were comprehensively searched for research on Eryngium. The search period was from 1966 to October 2018. The related articles were selected according to the inclusion and exclusion criterias in our study. Results: A total of 57 papers were enrolled in analyses. The findings showed that Iranian species of Eryngium, had a noticeable diverse of traditional medicinal uses and also broad range of pharmacological activities as well as various phytochemical compounds. Some remarkable biological and pharmacological activities of these species have been demonstrated in present scientific studies, including antimicrobial, cytotoxic and anticancer, anti-inflammatory, analgesic and antinociceptive activities as well as antioxidant, antidiabetic, anti-snake and anti-scorpion venom effects. Conclusion: Iranian Eryngium species have enormous potential for prospective preparation of herbal medicinal products and are good candidates for discovering new drugs.

关键词： Eryngium Iranian species Pharmacological activities Phytochemical compositions Traditional and ethnopharmacological uses

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Evaluation of scientific evidence for abortifacient medicinal plants mentioned in traditional Persian medicine

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Traditional Medicine Research 2020年第6期5卷 449-463页

作者： Ensiye aafi Malihe Tabarrai Mehran Mirabzadeh Ardakani Mohammad Reza Shams Ardakani Seyede nargess sadati lamardi Department of Traditional Pharmacy School of Persian MedicineTehran University of Medical SciencesTehranIran Department of Persian Medicine School of Persian MedicineTehran University of Medical SciencesTehranIran Department of Pharmacognosy Faculty of Pharmacy and Pharmaceutical Sciences Research CenterTehran University of Medical SciencesTehranIran

Background:Miscarriage or spontaneous ending to a pregnancy takes place at the early stages of pregnancy without *** women may use medicinal herbs to relieve some of the symptoms of pregnancy as they believe that all herbs are *** abortion-inducing herbs were mentioned by the famous Iranian philosophers,Avicenna and Aghili,in documents of traditional Persian medicine titled Al-Qanun Fi Al-Tibb(The Canon of Medicine,written by Avicenna in the 11th century)and Makhzan Al-adviyah(The Storehouse of Medicaments,written by Aghili in the 18th century).Methods:Electronic databases such as PubMed,Scopus,Google Scholar,Cochrane Library and Web of Science were searched to find new scientific evidence that these plants are toxic during *** was collected from 1831 to ***:Twenty-one plants were found to be abortive according to Al-Qanun Fi Al-Tibb(The Canon of Medicine)and Makhzan Al-adviyah(The Storehouse of Medicaments).Scientific research has shown that these plants possess abortifacient effects by the mechanisms of toxic alkaloids,uterine stimulants,and emmenagogue that interferes with implantation and results in fetus *** studies included in vivo or in vitro *** of these plants showed abortifacient effects by more than one *** graveolens,Nigella sativa,Curcuma longa,Lupinus termis,Apium graveolens,Mentha longifolia,and Peganum harmala possess uterine stimulant *** graveolens,Juniperus sabina,Cicer arietinum,Piper longum,Artemisia absinthium,and Citrullus colocynthis interfere with *** graveolens,Nigella sativa,Curcuma longa,Tanacetum parthenium,Piper longum,Laurus nobilis,Apium graveolens,Mentha longifolia,and Cinnamomum iners exhibit emmenagogue *** termis,Delphinium staphisagria,Laurus nobilis,Trigonella foenum-graecum,Zataria multiflora,and Artemisia absinthium contain toxic alkaloids and possess teratogenic ***:The results of this study of tradi

关键词： Miscarriage Medicinal plants Traditional Persian medicine Abortifacient

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