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Adjuvant activity of Pasteurella multocida A strain,Pasteurella multocida B strain and Salmonella typhimurium bacterial DNA on cellular and humoral immunity responses against Pasteurella multocida specific strain infections in Balb/c mice

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Asian Pacific Journal of Tropical Medicine 2018年第5期11卷 336-341页

作者： Maryam Homayoon Yahya Tahamtan mohammad Kargar seyed mohammad hossein hosseini Abbas Akhavan Sepahy Department of Biology Science and Research BranchIslamic Azad University Department of Microbiology Shiraz BranchRazi Vaccine and Serum Research InstituteAgriculture ResearchEducation and Extension Organization Department of Microbiology Jahrom Branch Islamic Azad University Department of Microbiology Tehran North BranchIslamic Azad University

Objective: To evaluate the effects of Pasteurella multocida(P. multocida) vaccines on the expression and release of antibodies, interleukin(IL)-6 and IL-12 by serum. Methods: Balb/c mice were immunized with two formalin and iron inactivated vaccine doses within 2 weeks. The vaccines were adjuvant with P. multocida A strain, P. multocida B strain and Salmonella typhimurium bacterial DNA(AbDNA, BbDNA and SbDNA for short, respectively). The animals were challenged 4 weeks after immunization. Blood of mice was collected to detect the change of specific antibody, IL-6, and IL-12 using ELISA. Results: The specific antibody and interleukins in the immunized group increased significantly compared to the control mice after vaccination and challenge(P<0.05). The highest release of these cytokines was obtained by *** inactivated with iron and adjuvant with AbDNA at a concentration of 25 μg/mL. The antibody titer peak was 0.447 in mice vaccinated with iron-killed whole-cell antigen adjunct with AbDNA. The time-courses of release showed that bacterial DNA was able to stimulate IL-6 and IL-12 production more than alum(P<0.05). Conclusions: Our findings introduce that bacterial DNA is capable of releasing an immunological response with several *** indicate that bacterial DNA entrapped with killed P. multocida antigen is a new and effective adjuvant to enhance specific immunity and resistance of animal against the infectious pathogen, which could simplify the development of highly promising strong adjuvant.

关键词： Pasteurella multocida Bacterial DNA Adjuvant activity Vaccine Immunity Balb/c mice

New insights on the role of chondroitin sulfate proteoglycans in neural stem cell–mediated repair in spinal cord injury

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Neural Regeneration Research 2025年第6期20卷 1699-1700页

作者： seyed Mojtaba hosseini Soheila Karimi-Abdolrezaee Department of Physiology and Pathophysiology Spinal Cord Research CentreRady Faculty of Health SciencesUniversity of ManitobaWinnipegMBCanada Manitoba Multiple Sclerosis Research Center WinnipegMBCanada Children Hospital Research Institute of Manitoba WinnipegMBCanada

Extensive neurodegeneration is a hallmark of traumatic spinal cord injury (SCI) that underlies permanent sensorimotor and autonomic impairments (Alizadeh et al.,2019).Following the primary impact,the spinal cord undergoes a cascade of secondary injury mechanisms that are driven by disruption of the blood-spinal cord ba rrier,vascula r inju ry,glial reactivity,neu roinfla mmation,oxidative stress,lipid peroxidation,and glutamate excitotoxicity that culminate in neuronal and oligodendroglial cell death,demyelination,and axonal damage(Alizadeh et al.,2019).To achieve a meaningful functional recovery after SCI,regeneration of new neurons and oligodendrocytes and their successful growth and integration within the neural network are critical steps for reconstructing the damaged spinal cord tissue (Fischer et al.,2020).

关键词： peroxidation Fischer injury

Multidisciplinary design optimization of a dual-spin guided vehicle

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Defence Technology（防务技术） 2024年第7期37卷 133-148页

作者： Jalal Karimi mohammad Reza Rajabi seyed hossein Sadati seyed Mahid hosseini Department of Aerospace Engineering Malek Ashtar University of TechnologyTehranIran

In this research,a Multidisciplinary Design Optimization approach is proposed for the dual-spin guided flying projectile design considering external and internal parts of the body as design *** this way,a parametric formulation is *** related disciplines,including structure,aerodynamics,guidance,and control are *** total mass,maximum aerodynamic control effectiveness,minimum miss distance,maximum yield stress in all subsystems,controllability and gyroscopic stability constraints are some of objectives/constraints taken into *** problem is formulated in All-At-Ones Multidisciplinary Design Optimization approach structure and solved by Simulated Annealing and minimax *** optimal configurations are evaluated in various *** resulted optimal configurations have met all design objectives and constraints.

关键词： Flying projectile optimal design All-at-ones multidisciplinary optimization Structure discipline Guidance and control discipline Aerodynamic discipline

Enhanced microstructural and mechanical properties of Stellite/WC nanocomposite on Inconel 718 deposited through vibration-assisted laser cladding

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International Journal of Minerals,Metallurgy and Materials 2022年第2期29卷 327-334页

作者： hossein hosseini-Tayeb seyed Mahdi Rafiaei Daneshpajoohan Pishro Higher Education Institute IsfahanIran Department of Materials Science and Engineering Golpayegan University of TechnologyGolpayeganIsfahanIran

Stellite-21/WC nanopowders were deposited on Inconel through vibration-assisted laser cladding with different laser *** and scanning electron microscopy,hardness measurements,and wear characterizations were employed to understand the microstructural and mechanical behaviors of the *** showed that varying the cooling rate exerted remarkable effects on the microstructure of the as-cladded ***,increasing the laser power from 150 W to 250 W increased the heat input and the *** was affected by the scanning rate and powder feeding rate at a high laser power of 250 *** WC nanoparticles were added as reinforcement,the dilution magnitude intensified while the hardness value increased from HV 350 to HV *** wear characterizations indicated that the composites containing 3 wt%WC nanoparticles possessed the highest wear resistance.

关键词： Stellite WC nanoparticles mechanical properties laser cladding

Fabrication of phosphor bronze/Al two-phase material by recycling phosphor bronze chips using hot extrusion process and investigation of their microstructural and mechanical properties

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International Journal of Minerals,Metallurgy and Materials 2020年第6期27卷 809-817页

作者： Majid hosseini mohammad hossein Paydar Department of Materials Science and Engineering School of EngineeringShiraz UniversityShiraz 71964-84334Iran

Despite the existence of conventional methods for recycling chips,solid-state techniques have become popular,whereby waste metals are directly recycled into consolidated products with the desired shapes and *** investigated the feasibility of recycling phosphor bronze chips through a hot extrusion process using aluminum powder as a metal binder for the fabrication of a metal-fiber-reinforced aluminum matrix *** do so,mixtures containing 20 vol%–50 vol%of chips were prepared,cold-compacted,and *** quality of the consolidated samples was evaluated by determining the density of the fabricated composites and studying their *** addition,we performed tensile and hardness tests to evaluate the mechanical properties of the fabricated *** also analyzed the fracture surfaces of the samples to study the fracture mechanism as a function of the volume fraction of phosphor bronze chips in the fabricated *** results indicated that the most effective consolidation occurred in the sample containing 20 vol%of chips extruded at 465℃in which the chips serve as ideal fibers for improving the mechanical properties,especially the ultimate tensile strength,in comparison with those of Al matrixes that contain no chips but are produced under the same conditions.

关键词： recycling hot extrusion metal–metal composite phosphor bronze chips aluminum powder

A novel technology for control of variable speed pumped storage power plant

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Journal of Central South University 2016年第8期23卷 2008-2023页

作者： seyed mohammad Hassan hosseini mohammad Reza Semsar Department of Electrical Engineering Islamic Azad University

Variable speed pumped storage machines are used extensively in wind power plant and pumped storage power plant. This paper presents direct torque and flux control(DTFC) of a variable speed pumped storage power plant(VSPSP). By this method both torque and flux have been applied to control the VSPSP. The comparison between VSPSP's control strategies is studied. At the first, a wind turbine with the capacity 2.2 k W and DTFC control strategies simulated then a 250 MW VSPSP is simulated with all of its parts(including electrical, mechanical, hydraulic and its control system) by MATLAB software. In all of simulations, both converters including two-level voltage source converter(2LVSC) and three-level voltage source converter(3LVSC) are applied. The results of applying 2LVSC and 3LVSC are the rapid dynamic responses with better efficiency, reducing the total harmonic distortion(THD) and ripple of rotor torque and flux.

关键词： direct torque and flux control(DTFC) two-level & three-level voltage source converter(2LVSC&3LVSC) variable speed pumped storage power plant(VSPSP)

Assessment of seismic amplification factor of excavation with support system

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Earthquake Engineering and Engineering Vibration 2019年第3期18卷 555-566页

作者： Hamidreza Tavakoli Saman Soleimani Kutanaei seyed hossein hosseini Department of Civil Engineering Babol University of Technology P.O. Box 484 Babol Iran Department of Civil Engineering Rouzbahan Institute of Higher Education Sari Iran Department of Civil Engineering Hamedan Branch Islamic Azad University P.O. Box 65181-15743 Hamedan Iran

Retaining walls have been used in many construction projects such as for road and inclined surfaces protection. The damage caused by an earthquake depends on the fundamental frequency, amplitude and the duration of the seismic motion. These parameters strongly depend on the seismic properties of the layers that are near the surface. In the study of retaining walls, in addition to the infl uence of soil, the infl uence of topography is also important. In the present study, site response analysis is performed by using fi nite element software PLAXIS to obtain the eff ect of various factors such as embedded length of the sheet pile, underground water table, length and angle of the nail, shear wave velocity of soil on site eff ect and dynamic response. Moreover, for better understanding of the eff ect of the above parameters, the stability analysis was performed by using shear reduction method. The results show that an increase in the embedded length of the sheet pile and the length of nailing causes an increase in the amplifi cation factor. Moreover, for shear-wave velocity in the range of 200- 600 m/s, the amplifi cation factor increases with increase of the shear-wave velocity due to the decrease of nonlinear behavior.

关键词： amplifi cation factor safety factor shear wave velocity nailing sheet pile

A generalized set of correlations for plus fraction characterization

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Petroleum Science 2012年第3期9卷 370-378页

作者： JAMIALAHMADI Mohamad ZANGENEH hossein hosseini seyed Sajad Petroleum Engineering Department Petroleum University of Technology Chemical & Petroleum Engineering Department Sharif University of Technology

The importance of accurate determination of the critical properties of plus fractions in prediction of phase behaviour of hydrocarbon mixtures by equations of state is well known in the petroleum industry. It has been stated in various papers （Elsharkawy, 2001） that using the plus fraction as a single group in equation of state calculations reduces the accuracy of the results. However in this work it has been shown that using the proper values of critical temperature and pressure for the plus fraction group can estimate the properties of hydrocarbon mixtures, and they are accurate enough to be used in reservoir engineering and enhanced oil recovery calculations. In this paper, a new method is proposed for calculating the critical properties of plus fractions of petroleum fluids. One can use this method either in predicting critical pressure and temperature of single carbon numbers （SCNs） after the splitting process or in predicting critical pressure and temperature of the plus fraction as a single group. A comparison study is performed against Riazi-Daubert correlation （Riazi and Daubert, 1987） and Sancet correlations （Sancet, 2007） for 25 oil samples taken from 14 fields from southwest Iran. The results indicate the superiority of the proposed method to the Riazi-Daubert and Sancet correlations.

关键词： Plus fraction critical properties correlation single carbon number bubble point calculations

Complete Moment Convergence for the Dependent Linear Processes with Random Coefficients

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Acta Mathematica Sinica,English Series 2019年第8期35卷 1321-1333页

作者： seyed mohammad hosseini Ahmad NEZAKATI Faculty of Mathematical Sciences Shahrood University of Technology

In this paper, we investigate the complete moment convergence for dependent linear processes with random coefficients to form Xt =∑j^∞=∞ Aj∈t-j,where {∈n, n ∈ Z} is a sequence of END stochastically dominated random variables and {An,n ∈ Z} is a sequence of random varibles. As applications, the convergence rate, Marcinkiewicz-Zvgmund strong law and strong law of large numbers for this linear process are established.

关键词： Complete moment convergence ext ended negatively dependen t random variables linear processes random coefficients