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作者：陈芳芳王冠奎 James I.Griffin Barbara Brenneman Nirmal K.Banda V.Michael Holers Donald S.Backos 吴林平 seyed moein monghimi Dmitri Simberg 吉林大学

成果内容研究属于纳米医学转化领域成果,应用医学免疫学及化学、材料学的技术揭示纳米材料与补体、免疫细胞等固有免疫应答系统相互作用的结果及客观规律。纳米材料造影剂和药物载体静脉注射后吸附血液蛋白质形成蛋白冠,蛋白冠的组成取...

成果内容研究属于纳米医学转化领域成果,应用医学免疫学及化学、材料学的技术揭示纳米材料与补体、免疫细胞等固有免疫应答系统相互作用的结果及客观规律。纳米材料造影剂和药物载体静脉注射后吸附血液蛋白质形成蛋白冠,蛋白冠的组成取决于纳米材料固有的物理化学性质,其在纳米材料药代动力学和生物学性能中发挥调节作用,对其靶向、免疫识别和毒性均有影响。本研究尝试通过工程学超顺磁氧化

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Post-discharge follow-up of patients with spine trauma in the National Spinal Cord Injury Registry of Iran during the COVID-19 pandemic:Challenges and lessons learned

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Chinese Journal of Traumatology 2024年第3期27卷 173-179页

作者： Zahra Azadmanjir moein Khormali Mohsen Sadeghi-Naini Vali Baigi Habibollah Pirnejad Mohammad Dashtkoohi Zahra Ghodsi seyed Behnam Jazayeri Aidin Shakeri Mahdi Mohammadzadeh Laleh Bagheri Mohammad-Sajad Lotfi Salman Daliri Amir Azarhomayoun Homayoun Sadeghi-Bazargani Gerard O'reilly Vafa Rahimi-Movaghai Health Information Management Department School of Allied Medical SciencesTehran University of Medical SciencesTehranIran Sina Trauma and Surgery Research Center Tehran University of Medical SciencesTehranIran Department of Neurosurgery Lorestan University of Medical SciencesKhoram-AbadIran Department of Epidemiology and Biostatistics School of Public HealthTehran University of Medical SciencesTehranIran Patient Safety Research Center Clinical Rsearch Institute Urma Universty of Medical SciencesUrmaIran Erasmus School of Health Policy&Management(ESHPM) Erasmus University RotterdamRoterdamthe Netherlands Brain and Spinal Cord Injury Research Center Neuroscience InstituteTehran University of Medical SciencesTehranIran Students Scientifc Research Center(SSRC) Tehran University of Medical SciencesTehranIran Department of Neurosurgery Arak University of Medical SciencesArakIran Trauma Research Center Kashan University of Medical SciencesKashanIran Shahid Rahnemoun Hospital Shahid Sadoughi University of Medical SciencesYazdIran Trauma Nuring Rearch entre Faculty of Nursing and Midwifry Kahan Universty of Medical Sciences Kahan Iran Clinical Research Development Unit Imam Hossein HospitalShahroud University of Medical SciencesShahroudIran Research Center for Evidence Based Medicine Faculty of MedicineTabriz University of Medical SciencesTabrizIran Road Trafic Injury Research Center Tabriz University of Medical SciencesTabrizIran School of Public Health and Preventive Medicine Monash UniversityMelbourneAustralia National Trauma Research Institute The AlfredMelbourneAustralia Department of Neurosurgery Shariati HospitalTehran University of Medical SciencesTehranIran Universal Scientific Education and Research Network(USERN) TehranIran Institute of Biochemistry and Biophysics University of TehranTehranIran

Purpose:The purpose of the National Spinal Cord Injury Registry of Iran(NSCIR-IR)is to create an infrastructure to assess the quality of care for spine trauma and in this study,we aim to investigate whether the NSCIR-IR successfully provides necessary post-discharge follow-up data for these ***:An observational prospective study was conducted from April 11,2021 to April 22,2022 in 8 centers enrolled in NSCIR-IR,respectively Arak,Rasht,Urmia,Shahroud,Yazd,Kashan,Tabriz,and *** were classified into 3 groups based on their need for care resources,respectively:(1)non-spinal cord injury(SCI)patients without surgery(group 1),(2)non-SCI patients with surgery(group 2),and(3)SCI patients(group 3).The assessment tool was a self-designed questionnaire to evaluate the care quality in 3 phases:pre-hospital,in-hospital,and *** data from the first 2 phases were collected through the *** post-hospital data were collected by conducting follow-up *** follow-ups were conducted for groups 1 and 2(non-SCI patients),while group 3(SCI patients)had a face-to-face *** study took place during the COVID-19 *** on age and time interval from injury to follow-up were expressed as mean±standard deviation(SD)and response rate and follow-up loss as a ***:Altogether 1538 telephone follow-up records related to 1292 patients were registered in the *** the total calls,918(71.05%)were related to successful follow-ups,but 38 cases died and thus were excluded from data *** the end,post-hospital data from 880 patients alive were *** success rate of follow-ups by telephone for groups 1 and 2 was 73.38%and 67.05%respectively,compared to 66.67%by face-to-face visits for group 3,which was very hard during the COVID-19 *** data completion rate after discharge ranged from 48%-100%,22%-100%and 29%-100%for groups ***:To improve patient accessibility,NSCIR-IR should take me

关键词： Follow-up studies Spinal injuries Spinal cord injuries COVID-19 NSCIR-IR

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National Spinal Cord Injury Registry of Iran(NSCIR-IR)-a critical appraisal of its strengths and weaknesses

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Chinese Journal of Traumatology 2019年第5期22卷 300-303页

作者： Mahdi Sharif-Alhoseini Zahra Azadmanjir Mohsen Sadeghi-Naini Zahra Ghodsi Khatereh Naghdi Mahdi Mohammadzadeh Amir AzarHomayoun Kazem Zendehdel moein Khormali Farideh Sadeghian seyed Behzad Jazayeri Mojtaba Sehat Habibollah Pirnejad Edward C.Benzel Gerard O'Reilly Michael G.Fehlings Alexander R.Vaccaro Vafa Rahimi-Movaghar Sina Trauma and Surgery Research Center Tehran University of Medical SciencesTehranIran Toronto Western Hospital University Health NetworkTorontoOntarioCanada Department of Orthopaedic Surgery The Rothman InstituteThomas Jefferson UniversityPhiladelphiaUSA Brain and Spinal Cord Injury Research Center Neuroscience InstituteTehran University of Medical SciencesTehranIran Department of Health Information Management School of Allied Medical SciencesTehran University of Medical SciencesTehranIran Trauma Research Center Kashan University of Medical SciencesKashanIran Cancer Research Center Cancer InstituteTehran University of Medical SciencesTehranIran Students'Scientific Research Center Tehran University of Medical SciencesTehranIran Center for Health Related Social and Behavioral Sciences Research Shahroud University of Medical SciencesShahroudIran Department of Health Information Technology Urmia University of Medical SciencesUrmiaIran Cleveland Clinic Foundation Department of NeurosurgeryClevelandOHUSA Department of Epidemiology and Preventive Medicine School of Public Health and Preventive MedicineMonash UniversityMelbourneAustralia

The National Spinal Cord Injury Registry of Iran(NSCIR-IR)is a not-for-profit,hospital-based,and prospective observational registry that appraises the quality of care,long-term outcomes and the personal and psychological burden of traumatic spinal cord injury in *** validity in every registry includes rigorous attention to data *** quality assurance is essential for any registry to make sure that correct patients are being enrolled and that the data being collected are *** reviewed strengths and weaknesses of the NSCIR-IR while considering the methodological guidelines and recommendations for efficient and rational governance of patient *** summary,the steering committee,funded and maintained by the Ministry of Health and Medical Education of Iran,the international collaborations,continued staff training,suitable data quality,and the ethical approval are considered to be the strengths of the registry,while limited human and financial resources,poor interoperability with other health systems,and time-consuming processes are among its main weaknesses.

关键词： Spinal cord injuries Injury registries Data accuracy Iran

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Evaluating mechanism and severity of injuries among trauma patients admitted to Sina Hospital,the National Trauma Registry of Iran

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Chinese Journal of Traumatology 2021年第3期24卷 153-158页

作者： Mina Saeednejad Mohammadreza Zafarghandi Narjes Khalili Vali Baigi moein Khormali Zahra Ghodsi Mahdi Sharif-Alhoseini Reilly Gerard M.O’ Khatereh Naghdi Melika Khaleghi-Nekou seyed mohammad Piri Vafa Rahimi-Movaghar Somayeh Bahrami Marjan Laal Mahdi Mohammadzadeh Esmaeil Fakharian Habibollah Pirnejad Hamid Pahlavanhosseini Payman Salamati Homayoun Sadeghi-Bazargani Sina Trauma and Surgery Research Center Tehran University of Medical SciencesTehranIran Preventive Medicine and Public Health Research Center Department of Community and Family MedicineSchool of MedicineIran University of Medical SciencesTehranIran National Health and Medical Research Council(NHMRC) AustraliaNational Trauma Research InstituteThe Alfred Hospital and Monash UniversityMelbourneAustralia Trauma Research Center Kashan University of Medical SciencesKashanIran Patient Safety Research Center Urmia University of Medical SciencesUrmiaIran Trauma Research Center Shahid Sadoughi University of Medical SciencesYazdIRIran Road Traffic Injury Research Center Tabriz University of Medical SciencesTabrizIran

Purpose:Injuries are one of the leading causes of death and lead to a high social and financial *** patterns can vary significantly among different age groups and body *** study aimed to evaluate the relationship between mechanism of injury,patient comorbidities and severity of ***:The study included trauma patients from July 2016 to June 2018,who were admitted to Sina Hospital,Tehran,*** inclusion criteria were all injured patients who had at least one of the following:hospital length of stay more than 24 h,death in hospital,and transfer from the intensive care unit of another *** collection was performed using the National Trauma Registry of Iran minimum ***:The most common injury mechanism was road traffic injuries(49.0%),followed by falls(25.5%).The mean age of those who fell was significantly higher in comparison with other mechanisms(p<0.001).Severe extremity injuries occurred more often in the fall group than in the vehicle collision group(69.0%vs.43.5%,p<0.001).Moreover,cases of severe multiple trauma were higher amongst vehicle collisions than injuries caused by falls(27.8%vs.12.9%,p=0.003).Conclusion:Comparing falls with motor vehicle collisions,patients who fell were older and sustained more extremity *** injured by motor vehicle collision were more likely to have sustained multiple trauma than those presenting with *** of the relationship between mechanisms and consequences of injuries may lead to more effective interventions.

关键词： Wounds and injuries Multiple trauma Abbreviated injury scale Injury severity score Registries

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