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Endoscopic ultrasound-guided biliary drainage with placement of a fully covered metal stent for malignant biliary obstruction

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World Journal of Gastroenterology 2012年第20期18卷 2526-2532页

作者： Tae Hyeon Kim Seong Hun Kim Hyo Jeong Oh Young Woo Sohn seung ok lee Department of Internal Medicine School of MedicineWonkwang UniversityIksanChonbuk 570-749 South Korea Department of Internal Medicine Chonbuk National University Medical School and HospitalJeonjuChonbuk 561-712South Korea Department of Internal Medicine School of MedicineWonkwang UniversitySanbon Gyounggi 570-749South Korea

AIM:To determine the utility of endoscopic ultrasoundguided biliary drainage(EUS-BD)with a fully covered self-expandable metal stent for managing malignant biliary stricture. METHODS:We collected data from 13 patients who presented with malignant biliary obstruction and underwent EUS-BD with a nitinol fully covered selfexpandable metal stent when endoscopic retrograde cholangiopancreatography(ERCP)***-guided choledochoduodenostomy(EUS-CD)and EUS-guided hepaticogastrostomy(EUS-HG)was performed in 9 patients and 4 patients,respectively. RESULTS:The technical and functional success rate was 92.3%(12/13)and 91.7%(11/12),respectively. Using an intrahepatic approach(EUS-HG,n=4),there was mild peritonitis(n=1)and migration of the metal stent to the stomach(n=1).With an extrahepatic approach(EUS-CD,n=10),there was pneumoperitoneum(n=2),migration(n=2),and mild peritonitis (n=1).All patients were managed conservatively with *** follow-up(range,1-12 mo),there was re-intervention(4/13 cases,30.7%)necessitated by stent migration(n=2)and stent occlusion(n=2). CONCLUSION:EUS-BD with a nitinol fully covered self-expandable metal stent may be a feasible and effective treatment option in patients with malignant biliary obstruction when ERCP fails.

关键词： Endoscopic ultrasound-guided Biliary drainage Metal stent Biliary obstruction

Classification of hepatobiliary scintigraphy patterns in segmented gallbladder according to anatomical discordance

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World Journal of Clinical Cases 2023年第11期11卷 2423-2434页

作者： Yun-Chae lee Won-Sik Jung Chang-Hun lee Seong-Hun Kim seung-ok lee Division of Gastroenterology Department of Internal MedicineJeonbuk National University Medical SchoolJeonju 54907JeonbukSouth Korea Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital Jeonju 54907JeonbukSouth Korea

BACKGROUND Hepatobiliary scintigraphy(HBS)is a useful diagnostic imaging technique that uses radiotracers to evaluate the function of the gallbladder(GB)and biliary *** segmented GB,some HBS images reveal a discordant GB boundary as compared to anatomical *** To evaluate the characteristics of HBS in segmented GB and determine the clinical relevance according to HBS *** A total of 268 patients with chronic cholecystitis,gallstones,or biliary colic symptoms who underwent HBS between 2011 and 2020 were *** GB was defined as segmental luminal narrowing of the GB body on computed tomography(CT)or magnetic resonance(MR)images,and HBS was examined 1 mo before or after CT or *** GB was classified into 3 types based on the filling and emptying patterns of the proximal and distal segments according to the characteristics of HBS images,and GB ejection fraction(GBEF)was identified:Type 1 was defined as a normal filling and emptying pattern;Type 2 was defined as an emptying defect on the distal segment;and Type 3 was defined as a filling defect in the distal *** Segmented GB accounted for 63 cases(23.5%),including 36 patients(57.1%)with Type 1,18 patients(28.6%)with Type 2,and 9 patients(14.3%)with Type 3 emptying ***,approximately 43%of HBS images showed a discordant pattern as compared to anatomical imaging of segmented *** there were no significant differences in clinical symptoms,rate of cholecystectomy,or pathological findings based on the type,most gallstones occurred in the distal *** GBEF was 62.50%±24.79%for Type 1,75.89%±17.21%for Type 2,and 88.56%±7.20%for Type *** 1 showed no difference in reported GBEF compared to the non-segmented GB group(62.50%±24.79%vs 67.40%±21.78%).In contrast,the reported GBEF was higher in Types 2 and 3 with defective emptying and filling when compared to Type 1(80.11%±15.70%vs 62.57%±24.79%;P=0.001).CONCLUSION In segmented GB,discordance i

关键词： Gallbladder Segmented Gallbladder emptying Radionuclide imaging Misdiagnosis Cholecystitis

3-Dimensional liver volume assessment in patients with hepatitis B virus-related liver cirrhosis during long-term oral nucleos(t)ide analogues therapy

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World Journal of Gastroenterology 2017年第2期23卷 297-305页

作者： Chang Hun lee In Hee Kim Jin Chang Moon seung Young Seo Seong Hun Kim Sang Wook Kim seung ok lee Soo Teik lee Dae Ghon Kim Jae Do Yang Hee Chul Yu Division of Gastroenterology Department of Internal MedicineChonbuk National University Medical School and Hospital Department of Surgery Chonbuk National University Medical School and Hospital

AIMTo assess the effect of long-term oral nucleos(t)ide analogues (NUCs) therapy on liver volume change in patients with suppress hepatitis B virus (HBV)-related liver *** reviewed the data of naïve patients with HBV-related liver cirrhosis, who had taken oral NUCs therapy, between 2003 and 2007 at Chonbuk University Hospital. We analyzed two consecutive sets of abdominal computerized tomography scans-one at the time of treatment initiation and another at the second-year follow-up. Liver volume was calculated by 3-dimensional liver extraction volumetry *** total of 55 patients (34 males) were included. There was 114.3 mL ± 167.8 mL (12.9% ± 17.9%) of increase in liver volume during the two years of NUCs therapy (993.8 mL ± 242.8 mL at baseline vs 1108.1 mL ± 263.3 mL at two-year follow-up, P < 0.001). The ratio of the measured baseline liver volume to the estimated standard liver volume was improved from 70.8% to 78.0%. An increase in liver volume was shown not only in patients with compensated cirrhosis (P = 0.046) but also in those with decompensated cirrhosis (P < 0.001). Significant factors for volume increases were Child-Turcotte-Pugh grade and model for end-stage liver disease score improvement without virological breakthrough. In multiple linear regression analysis, delta albumin and delta alanine aminotransferase levels showed a significant association with the increase in liver volume (P = 0.002 and 0.005, respectively).CONCLUSIONLong-term oral NUCs therapy in patients with HBV-related liver cirrhosis lead to significant increase in liver volume assessed with 3-dimensional liver extraction volumetry program.

关键词： Antiviral agents Liver cirrhosis Liver regeneration Image processing Computer-assisted

Prevalence of clonorchiasis in patients with gastrointestinal disease: A Korean nationwide multicenter survey

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World Journal of Gastroenterology 2009年第1期15卷 86-94页

作者： Ho Gak Kim Jimin Han Myung-Hwan Kim Kyu Hyun Cho Im Hee Shin Gwang Ha Kim Jae Seon Kim Jin Bong Kim Tae Nyeun Kim Tae Hyeon Kim Tae Hyo Kim Jae Woo Kim Ji Kon Ryu Young-Soo Moon Jong Ho Moon Sung Jae Park Chan Guk Park Sung-Jo Bang Chang Heon Yang Kyo-Sang Yoo Byung Moo Yoo Kyu Taek lee Dong Ki lee Byung Seok lee Sang Soo lee seung ok lee Woo Jin lee Chang Min Cho Young-Eun Joo Gab Jin Cheon Young Woo Choi Jae Bok Chung Yong Bum Yoon Department of Internal Medicine Catholic University of Daegu School of Medicine Daegu 705-718 South Korea Department of Internal Medicine Asan Medical Center University of Ulsan College of Medicine Seoul 138-736 South Korea Department of Medical Statistics Catholic University of Daegu School of Medicine Daegu 705-718 South Korea Department of Internal Medicine Pusan National University School of Medicine Busan 602-739 South Korea Department of Internal Medicine Korea University College of Medicine Seoul 136-705 South Korea Department of Internal Medicine Hallym University College of Medicine Chuncheon 200-704 South Korea Department of Internal Medicine Yeungnam University College of Medicine Daegu 705-717 South Korea Department of Internal Medicine Wonkwang University College of Medicine Iksan Jeonbuk 570-711 South Korea Department of Internal Medicine Gyeongsang National University School of Medicine Jinju Gyeongnam 660-702 South Korea Department of Internal Medicine Yonsei University Wonju College of Medicine Wonju Gangwon 220-701 South Korea Department of Internal Medicine Seoul National University College of Medicine Seoul 110-799 South Korea Department of Internal Medicine lnje University College of Medicine Seoul 139-713 South Korea Department of Internal Medicine Soonchunhyang University College of Medicine Bucheon Gyunggi 420-767 South Korea Department of Internal Medicine Inje University College of Medicine Busan 614-735 South Korea Department of Internal Medicine Chosun University College of Medicine Gwangju Jeonbuk 501-717 South Korea Department of Internal Medicine Ulsan University Hospital University of Ulsan College of Medicine Ulsan 681-714 South Korea Department of Internal Medicine Dongguk University College of Medicine Gyeongju Gyeongbuk 791-707 South Korea Department of Internal Medicine Hallym University College of Medicine Anyang Gyeonggi 431-070 South Korea Department of Internal Medicine Ajou University School of Medicine Suwon

AIM： To investigate prevalence of C/onorchis sinensis in patients with gastrointestinal symptoms, and the relation of the infection to hepatobiliary diseases in 26 hospitals in Korea. METHODS： Consecutive patients who had been admitted to the Division of Gastroenterology with gastrointestinal symptoms were enrolled from March to April 2005. Of those who had been diagnosed with clonorchiasis, epidemiology and correlation between infection and hepatobiliary diseases were surveyed by questionnaire. RESULTS： Of 3080 patients with gastrointestinal diseases, 396 （12.9%） had clonorchiasis and 1140 patients （37.2%） had a history of eating raw freshwater fish. Of those with a history of raw freshwater fish ingestion, 238 （20.9%） patients had clonorchiasis. Cholangiocarcinoma was more prevalent in C. sinensis-infected patients than nonnfected patients [34/396 （8.6%） vs 145/2684 （5.4%）, P = 0.015]. Cholangiocarcinoma and clonorchiasis showed statistically significant positive cross-relation （P = 0.008）. Choledocholithiasis, cholecystolithiasis, cholangitis, hepatocellular carcinoma, and biliary pancreatitis did not correlate with clonorchiasis. CONCLUSION： Infection rate of clonorchiasis was still high in patients with gastrointestinal diseases in Korea, and has not decreased very much during the last two decades. Cholangiocarcinoma was related to clonorchiasis, which suggested an etiological role for the parasite.

关键词： Clonorchis sinensis Epidemiology Cholangiocarcinoma Korea Multicenter study Clonorchiasis

Application of ferrate(VI) in the treatment of industrial wastes containing metal-complexed cyanides : A green treatment

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Journal of Environmental Sciences 2009年第10期21卷 1347-1352页

作者： seung-Mok lee DIWAKAR Tiwari Department of Environmental Engineering Kwandong University Department of Chemistry School of Physical Sciences Mizoram University

Ferrate（VI） was employed for the oxidation of cyanide （CN） and simultaneous removal of copper or nickel in the mixed/complexed systems of CN-Cu, CN-Ni, or CN-Cu-Ni. The degradation of CN （1.00 mmol/L） and removal of Cu （0.095 mmol/L） were investigated as a function of Fe（Ⅵ） doses from 0.3-2.00 mmol/L at pH 10.0. It was found that Fe（Ⅵ） could readily oxidize CN and the reduction of Fe（Ⅵ） into Fe（Ⅲ） might serve efficiently for the removal of free copper ions. The increase in Fe（Ⅵ） dose apparently favoured the CN oxidation as well as Cu removal. Moreover, the pH dependence study （pH 10.0-13.0） revealed that the oxidation of CN was almost unaffected in the studied pH range （10.0-13.0）, however, the maximum removal efficiency of Cu was obtained at pH 13.0. Similarly, treatment was carded out for CN-Ni system having the initial Ni concentration of 0.170 mmol/L and CN concentration of 1.00 mmol with Fe（Ⅵ） dose 2.00 mmol at various pH values （10.0-12.0）. Results showed a partial oxidation of CN and partial removal of Ni. It can be observed that Fe（Ⅵ） can partially degrade the CN-Ni complex in this pH range. Further, Fe（Ⅵ） was applied for the treatment of simulated industrial waste/effluent waters treatment containing CN, Cu, and Ni.

关键词： cyanide metal-complexed cyanide oxidation copper nickel ferrate(Ⅵ)

Synergistically coupling of Ni–Fe LDH arrays with hollow Co–Mo sulfide nanotriangles for highly efficient overall water splitting

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Rare Metals 2024年第2期43卷 522-532页

作者： Yun Jae lee seung-Keun Park Department of Advanced Materials Engineering Chung-Ang UniversityAnseongGyeonggi-do17546Republic of Korea Department of Intelligent Energy and Industry Chung-Ang University84 Heukseok-ro Dongjak-guSeoul06974Republic of Korea Western Seoul Center Korea Basic Science Institute150 Bugahyeon-roSeodaemun-guSeoul03759Republic of Korea

Developing bifunctional catalysts that can catalyze both oxygen evolution reaction(OER)and hydrogen evolution reaction(HER)is pivotal to commercializing large-scale water ***,a novel hollow nanotriangle composed of NiFe LDH-CoMoS_(x) heterojunction(H-CMSx@NiFe LDH)is proposed as a highly efficient bifunctional electrocatalyst for both OER and *** fabricate a heterojunction system,ultra-thin nickel–iron layered double hydroxide(NiFe LDH)nanosheets are uniformly electrodeposited onto a metal–organic framework-derived hollow CoMoS_(x) *** strong coupling of CoMoS_(x) and NiFe LDH catalysts forms the intimate heterojunction interfaces to facilitate interfacial charge transfer,which is favorable to enhance the bifunctional catalytic ***,the large void of CoMoS_(x) nanotriangles and interconnected ultra-thin NiFe LDH nanosheets result in good electrolyte penetration and gas ***,the as-prepared H-CMSx@NiFe LDH on nickel foam(NF)exhibits an impressive catalytic activity and durability for OER and HER activities,delivering a current density of 100 mA·cm^(−2) at the small overpotentials of 214 and 299 mV in OER and HER,***,H-CMSx@NiFe LDH/NF proves to be an effective electrode for an alkaline electrolyzer,as a voltage of only 1.99 V is enough to achieve a current density voltage of only 1.99 V is enough to achieve a current density of 400 mA·cm^(−2) with no degradation in performance over 50 h.

关键词： Overall water splitting Metal-organic framework Molybdenum sulfide Layered double hydroxide Heterojunction

Improvement in Background Error Covariances Using Ensemble Forecasts for Assimilation of High-Resolution Satellite Data

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Advances in Atmospheric Sciences 2011年第4期28卷 758-774页

作者： seung-Woo lee Dong-Kyou lee School of Earth and Environmental Sciences Seoul National University

Satellite data obtained over synoptic data-sparse regions such as an ocean contribute toward improving the quality of the initial state of limited-area models. Background error covariances are crucial to the proper distribution of satellite-observed information in variational data assimilation. In the NMC （National Meteorological Center） method, background error covariances are underestimated over data-sparse regions such as an ocean because of small differences between different forecast times. Thus, it is necessary to reconstruct and tune the background error covariances so as to maximize the usefulness of the satellite data for the initial state of limited-area models, especially over an ocean where there is a lack of conventional data. In this study, we attempted to estimate background error covariances so as to provide adequate error statistics for data-sparse regions by using ensemble forecasts of optimal perturbations using bred vectors. The background error covariances estimated by the ensemble method reduced the overestimation of error amplitude obtained by the NMC method. By employing an appropriate horizontal length scale to exclude spurious correlations, the ensemble method produced better results than the NMC method in the assimilation of retrieved satellite data. Because the ensemble method distributes observed information over a limited local area, it would be more useful in the analysis of high-resolution satellite data. Accordingly, the performance of forecast models can be improved over the area where the satellite data are assimilated.

关键词： 3DVAR background error covariances retrieved satellite data assimilation ensemble forecasts.

Joint member angle limits of composite beams and CFT square columns

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Journal of Central South University 2013年第1期20卷 199-206页

作者： lee seung-Jo lee Kang-Guk Department of Architecture Chosun College of Science & Technology Research Center for Urban Affair Kyungil University

This work aims to understand the relationship between the member angle limit and the energy ratio for 24 test samples of composite beams and CFT square steel tube columns. This work also compares the formula applicability for member angle limit with the previous test result to provide the basic data for the design of composite beam-CFT column. The evaluation of the member angle limit was performed with concrete compressive strength (fC =22.16 MPa, 30.49 MPa), breadth-to-thickness ratio (B/t=25.0, 33.3, 43.5), and axial capacity ratio (N/N0=0, 0.3, 0.4, 0.5) as the main variables of the test samples. For the relationship between the member angle limit (Ru) and the energy ratio (ES/EC ), the test result shows that the energy ratio becomes lower as the axial capacity ratio and the breadth-to-thickness ratio increase. The energy ratio is lower for the Type B test sample compared with that of Types A and C. For the formula suggested by SATO, the test samples are distributed evenly for comparison between test values and the member angle limit; however, other formulas indicate a deviation. Specifically, for the comparison between R u,cal and R u (Test), Maeda's formula shows severe deviation.

关键词： square steel tube axial capacity ratio member angle limit breadth-to-thickness ratio

High-throughput computational-experimental screening protocol for the discovery of bimetallic catalysts

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npj Computational Materials 2021年第1期7卷 1232-1241页

作者： Byung Chul Yeo Hyunji Nam Hyobin Nam Min-Cheol Kim Hong Woo lee Sung-Chul Kim Sung ok Won Donghun Kim Kwan-Young lee seung Yong lee Sang Soo Han Computational Science Research Center Korea Institute of Science and TechnologySeoulRepublic of Korea Department of Energy Resources Engineering Pukyong National UniversityBusanRepublic of Korea Materials Architecturing Research Center Korea Institute of Science and TechnologySeoulRepublic of Korea Department of Chemical and Biological Engineering Korea UniversitySeoulRepublic of Korea Department of Nanomaterials Science and Engineering Korea University of Science and TechnologyDaejeonRepublic of Korea Advanced Analysis Center Korea Institute of Science and TechnologySeoulRepublic of Korea

To accelerate the discovery of materials through computations and experiments,a well-established protocol closely bridging these methods is *** introduce a high-throughput screening protocol for the discovery of bimetallic catalysts that replace palladium(Pd),where the similarities in the electronic density of states patterns were employed as a screening *** first-principles calculations,we screened 4350 bimetallic alloy structures and proposed eight candidates expected to have catalytic performance comparable to that of *** experiments demonstrate that four bimetallic catalysts indeed exhibit catalytic properties comparable to those of ***,we discover a bimetallic(Ni-Pt)catalyst that has not yet been reported for H_(2)O_(2) direct *** particular,Ni_(61)Pt_(39) outperforms the prototypical Pd catalyst for the chemical reaction and exhibits a 9.5-fold enhancement in cost-normalized *** protocol provides an opportunity for the catalyst discovery for the replacement or reduction in the use of the platinum-group metals.

关键词： synthesis catalyst bimetallic