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ASSOCIATION BETWEEN ACUPUNCTURE NEEDLING SENSATION(DE-QI) AND LOCAL SKIN BLOOD FLOW IN HEALTHY SUBJECTS:A SINGLE-BLIND, RANDOMIZED CONTROLLED TRIAL

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Journal of Integrative Medicine 2014年第3期 256-256页

作者： Kun Hyung kim seung Hee Noh Yu Ri kim Gi Young Yang Jae Kyu kim Division of Clinical Medicine School of Korean MedicinePusan National University Korean Medicine Hospital Pusan National University

Objective: De-qi refers to sensations generated by needle insertion into an acupuncture ***-qi sensation is believed to be associated with treatment effects of acupuncture with the increase of local blood flow, although some patients may feel these sensations *** study aimed to assess the association between the strength of de-qi sensation and local skin blood flow in healthy ***: Forty-five healthy subjects were randomized into real acupuncture(RA) group(n=15), Park-sham acupuncture(SA) group(n=15) and non-needling control(CO) group(n=15).A single acupuncture session was conducted on the right LI4 point with manual stimulation and 10-minute needle ***-qi sensation was assessed immediately after the removal of needling by the Southampton needle sensation *** skin blood flow recording within 2 cm in diameter of ipsilateral LI4 area was performed intermittently from just before the intervention to the end of the trial by the laser Doppler blood perfusion *** between the change of skin blood flow and strength of De-qi was ***: Median change of local skin blood flow from baseline to post-treatment was 48.85, 48.20 and 0.59 arbitrary unit(AU) in RA, SA and CO groups, *** total sensation score was 10, 3 and 0 of 51 points, *** significant correl ation between total sensation score and change of skin blood flow in the RA and SA groups was observed(0.105 9 of Spearman’s rho, P=0.57).Conclusion: The data suggest that there is no association between De-qi sensation and local skin blood flow after acupuncture in healthy *** role of De-qi sensation for physiological changes and clinical outcomes should be further investigated in future acupuncture trials.

关键词： SA AND LOCAL SKIN BLOOD FLOW IN HEALTHY SUBJECTS ASSOCIATION BETWEEN ACUPUNCTURE NEEDLING SENSATION DE-QI RANDOMIZED CONTROLLED TRIAL

Repair of heat-induced skin aging by herbal extracts and thermal protection factor(TPF)

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Repair of heat-induced skin aging by herbal extracts and the...

LATERAL STABILITY VERIFICATION OF A CANARD AIRPLANE WITH AND WITHOUT A VERTICAL PANEL

第九届中国化妆品学术研讨会

作者： Hyeon Chung kim Kuan Chi Hsu Sung Il Park Eui Dong Son Myeong Hoon Yeom Dae Jin Min Sang Hoon Han Hak Hee Kang Quen Quen He Jeong cheol Ha Su Sun An Jae Ho Yeon Amorepacific Corporation R&D Center

Long term exposure of skin to high temperature induces activation of transient receptor potential cation channel subfamily V member 1(TRPV-1), as well as increase of matrix metalloprotease 9(MMP-9), which breaks down extracellular matrix in skin. Thus, along with photo-aging, heat also accelerates skin-aging as a long term effect. Here, heat-absorbing substances with heat energy-blocking effects were screened, and the blockage rate was calculated as "Thermal Protection Factor(TPF)". Herbal plant extracts such as Prunus Mume fruit extract and Chamaecyparis Obtusa polysaccharide were able to reduce skin damage by reducing TRPV-1 activation, heat-induced MMP-9 expression and other heat-induced inflammatory responses such as monocyte chemoattractant protein-1(MCP-1) expression. Also, a cream containing heat-absorbing and modulating actives showed statistically significant skin elasticity and redness-controlling effects in a clinical study.

关键词： Heat,skin aging TPF Prunus Mume Chamaecyparis Obtusa TRPV-1

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Transactions of Nanjing University of Aeronautics and Astronautics 2003年第2期20卷 125-133页

作者：殷熙凤黄明信朴郁济金泳澈崔垣宗韩国航空大学校航空科学与飞行系韩国航空大学校宇航机械工程学院韩国航空大学校材料工程系

The lateral stability of Velocity-173, canard-pusher type airplane, has been investigated with and without an extended vertical panel. It is well known that Velocity-173 has an excellent longitudinal stability but a relatively poor lateral stability. To improve the lateral stability, two types of composite sandwich panel have been designed and attached to the vertical tail of Velocity-173. A series of flight test has been performed to measure the effects of the extended vertical tail. Analytical methods, such as maximum likelihood estimation method and real-time parameter estimation method, have been used to extract lateral controllability/stability derivatives from flight test data. This work validates the effects of an extended panel to the lateral stability.

关键词： flight test parameter estimation stability

Phytogenic feed additives alleviate pathogenic Escherichia coli-induced intestinal damage through improving barrier integrity and inhibiting inflammation in weaned pigs

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中国古文献中所看到的古代建筑结构力学认识研究

畜牧与生物技术杂志(英文版) 2023年第1期

作者： Se Yeon Chang Min Ho Song Ji Hwan Lee Han Jin Oh Yong Ju kim Jae Woo An Young Bin Go Dong cheol Song Hyun Ah.Cho seung Yeol Cho Dong Jun kim Mi Suk kim Hyeun Bum kim Jin Ho Cho

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中国文物科学研究 2014年第3期 59-61页

作者：金德文玄胜旭韩国国立文化财研究所建筑文化财研究室

考察古代人的结构力学认识,是对古建筑结构的分析及解释必不可少的研究之一。因为与现代建筑结构不同,古代建筑结构主要取决于当时工匠们的经验与直观判断。古代人对结构力学的认识概念,我们从中国古文献中可以看到。通过本研究发现,古... 详细信息

考察古代人的结构力学认识,是对古建筑结构的分析及解释必不可少的研究之一。因为与现代建筑结构不同,古代建筑结构主要取决于当时工匠们的经验与直观判断。古代人对结构力学的认识概念,我们从中国古文献中可以看到。通过本研究发现,古代人已经有对力与荷重的力学认识以及古建筑的对称结构就是从古代力学的平衡概念出发而发展的。

关键词：建筑结构力量荷重力的平衡力学认识

Diagnostic value of AFP-L3 and PIVKA-Ⅱin hepatocellular carcinoma according to total-AFP

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World Journal of Gastroenterology 2013年第3期19卷 339-346页

作者： Jong Young Choi seung Won Jung Hee Yeon kim Myungshin kim Yonggoo kim Dong Goo kim Eun-Jee Oh Department of Internal Medicine School of MedicineThe Catholic University of KoreaSeoul 137-701South Korea Department of Laboratory Medicine and Laboratory Development Evaluation Center School of MedicineThe Catholic University of KoreaSeoul 137-701South Korea Department of Surgery School of MedicineThe Catholic University of KoreaSeoul 137-701South Korea

AIM:To evaluate diagnostic value ofα-fetoprotein (AFP)-L3 and prothrombin induced by vitamin K absence-Ⅱ(PIVKA-Ⅱ)in hepatocellular carcinoma(HCC). METHODS:One hundred and sixty-eight patients during routine HCC surveillance were included in this *** the 168 patients,90(53.6%)had HCC including newly developed HCC(n=82)or recurrent HCC after treatment(n=8).Sera were obtained during their first evaluation for HCC development and at the time of HCC diagnosis before commencing HCC *** was diagnosed by histological examination,appropriate imaging characteristics-computed tomography or magnetic resonance *** sera were collected from 78 patients with benign liver disease(BLD),which were obtained during routine surveillance with a suspicion of ***,AFP-L3 and PIVKA-Ⅱwere measured in the same serum by microchip capillary electrophoresis and liquid-phase binding assay on a micro-total analysis system Wako i30 auto *** performance characteristics of three tests and combined tests for the diagnosis of HCC were obtained using receiver operating characteristic curves in all populations and subgroups with AFP200 ng/*** the 78 BLD patients,74(94.9%)patients had AFP5%) and PIVKA-Ⅱ(cut-off>40 AU/L),the sensitivity were 94.4%and specificity were 75.6%in all *** 112 patients

关键词： α-fetoprotein Prothrombin induced by vitamin K absence-Ⅱ Hepatocellular carcinoma Diagnosis Tumor marker

葱属蔬菜植物风味前体物质的合成途径及调节机制

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细胞生物学杂志 2007年第4期29卷 508-512页

作者：许真严永哲卢钢金千焕郭得平浙江大学农业与生物技术学院园艺系杭州310029 韩国农村振兴厅暖地农业研究所园艺部

葱属蔬菜植物风味前体物质S-烃基半胱氨酸亚砜是一类非蛋白含硫氨基酸(蒜氨酸类物质),在蒜氨酸酶的作用下形成独特的刺激性风味成分。现对风味前体物质的种类、功能、组织和亚细胞定位以及合成途径及合成过程的调控等方面的研究进展给... 详细信息

葱属蔬菜植物风味前体物质S-烃基半胱氨酸亚砜是一类非蛋白含硫氨基酸(蒜氨酸类物质),在蒜氨酸酶的作用下形成独特的刺激性风味成分。现对风味前体物质的种类、功能、组织和亚细胞定位以及合成途径及合成过程的调控等方面的研究进展给予概述。

关键词：风味前体物质葱属植物 S-烃基半胱氨酸亚砜

减量FOLFIRINOX方案挽救性治疗吉西他滨抵抗的晚期胰腺癌:一项Ⅱ期研究

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癌症 2018年第8期37卷 327-335页

作者： Jung Hoon kim Sang-cheol Lee Sung Yong Oh Seo-Young Song Namsu Lee Eun Mi Nam Soonil Lee In Gyu Hwang Hyo Rak Lee Kyu Taek Lee Sang-Byung Bae Han Jo kim Joung Soon Jang Do Hyoung Lim Hyun Woo Lee Seok Yun Kang Jung Hun Kang Department of Internal Medicine Institute of Health SciencesGyeongsang National University Divsion of Hematology and Oncology Department of Internal MedicineSoonchunhyang University HospitalCheonan Department of Internal Medicine Dong-A University Hospital Department of Internal Medicine Kangwon National University School of Medicine Divsion of Hematology and Oncology Department of Internal MedicineSoonchunhyang University HospitalSeoul Department of Internal Medicine Ewha Womans UniversityCollege of Medicine Department of Internal Medicine Dankook University Hospital Department of Internal Medicine Chung-Ang UniversityCollege of Medicine Division of Hematology and Medical Oncology Department of Internal MedicineKorea Cancer Hospital Department of Hematology-Oncology Ajou University Hospital

背景与目的奥沙利铂、伊立替康、氟尿嘧啶和亚叶酸的联合化疗方案(FOLFIRINOX)极大提高了晚期胰腺癌患者的生存期。然而,FOLFIRINOX方案作为吉西他滨失败后二线治疗的疗效尚未进行前瞻性的检测。我们研究了减量FOLFIRINOX方案治疗吉西... 详细信息

背景与目的奥沙利铂、伊立替康、氟尿嘧啶和亚叶酸的联合化疗方案(FOLFIRINOX)极大提高了晚期胰腺癌患者的生存期。然而,FOLFIRINOX方案作为吉西他滨失败后二线治疗的疗效尚未进行前瞻性的检测。我们研究了减量FOLFIRINOX方案治疗吉西他滨抵抗的晚期胰腺癌患者的可行性和安全性。方法在14家医院进行了这一多中心II期前瞻、开放标签的单臂研究。经组织学确诊为胰腺浸润性导管腺癌、有可测量或可评价的病灶、东部肿瘤协作组体能状况评分0或1分、器官功能良好、年龄19岁或以上的患者符合入组条件。减量FOLFIRINOX方案的组成:奥沙利铂65 mg/m2、伊立替康135 mg/m2和亚叶酸400 mg/m2,第1天静脉注射;5?氟尿嘧啶2000 mg/m2,第1–2天持续静脉输注46 h;每2周重复。主要终点为FOLIFLIOX治疗起始后的无进展生存期。次要终点为客观缓解率、疾病控制率、总生存期、安全性和耐受性。采用Kaplan?Meier法评估了总生存期和无进展生存期。结果我们招募了来自14个中心的39例患者。客观缓解率为10.3%,疾病控制率为64.1%。6个月和1年总生存率分别为59.0%和15.4%。中位无进展生存期和总生存期分别为3.8个月[95%置信区间(confidence interval,CI)=1.5–6.0个月]和8.5个月(95%CI=5.6–11.4个月)。3或4级不良事件为中性粒细胞减少(41%)、恶心(10.3%)、食欲减退(10.3%)、贫血(7.7%)、黏膜炎(7.7%)、肺炎/胸膜融合(5.1%)和乏力(5.1%)。发生1例由感染性休克引起的治疗相关死亡。结论减量FOLFIRINOX方案有望作为二线方案治疗吉西他滨抵抗的胰腺癌。

关键词：减量FOLFIRINOX方案二线治疗胰腺癌吉西他滨

Zn_2SiO_4∶Mn的VUV和UV光谱特性

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发光学报 2000年第4期21卷 349-352页

作者：尤洪鹏洪广言曾小青 kimChang-hong PyunChong-hong Parkcheol-hee 中国科学院长春应用化学研究所稀土化学与物理开放研究实验室吉林长130022 DivisionofAppliedScience

采用高温固相反应法以硅酸为原料合成了等离子显示用荧光体Zn2 SiO4 ∶Mn ,研究了Zn2 SiO4 ∶Mn的VUV和UV光谱特性 ,表明波长小于 2 0 0nm的部分的基质吸收带主要是氧的 2 p轨道到锌的 3d轨道跃迁产生的 ,波长大于 2 0 0nm的部分的基质... 详细信息

采用高温固相反应法以硅酸为原料合成了等离子显示用荧光体Zn2 SiO4 ∶Mn ,研究了Zn2 SiO4 ∶Mn的VUV和UV光谱特性 ,表明波长小于 2 0 0nm的部分的基质吸收带主要是氧的 2 p轨道到锌的 3d轨道跃迁产生的 ,波长大于 2 0 0nm的部分的基质吸收带是氧的 2 p轨道到硅的 3p轨道跃迁吸收。在VUV和UV激发下 ,Mn2 +的浓度与发射强度的相关性研究表明 ,在不同区域激发时荧光体的发射强度随着Mn2

关键词：硅酸锌掺杂锰离子高温固相反应法跃迁吸收等离子体平板显示技术紫外-可见激发光谱发射光谱显示材料等离子体荧光体