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A dose-dependent bimodal switch by homologous Aux/IAA transcriptional repressors

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Molecular Plant 2024年第9期17卷 1407-1422页

作者： Hyung-Taeg Cho Minsu Lee Hee-seung choi Kwang-Ho Maeng Kyeonghoon Lee Ha-Yeon Lee Anindya Ganguly Hoonyoung Park Chang-Hoi Ho Department of Biological Sciences Seoul National UniversitySeoulKorea School of Earth and Environmental Sciences Seoul National UniversitySeoulKorea Department of Climate and Energy Systems Engineering Ewha Womans UniversitySeoulKorea

Combinatorial interactions between different regulators diversify and enrich the chance of transcriptional regulation in eukaryotic ***,a dose-dependent functional switch of homologous transcriptional repressors has rarely been ***,we show that SHY2,an auxin/indole-3-acetic acid(Aux/IAA)repressor,exhibits a dose-dependent bimodal role in auxin-sensitive root-hair growth and gene transcrip-tion in Arabidopsis,whereas other Aux/lAA homologs consistently repress the auxin *** co-repressor(TOPLESS[TPL])-binding affinity of a bimodal Aux/IAA was lower than that of a consistently re-pressing Aux/*** switch of a single amino acid residue in the TPL-binding motif between the bimodal form and the consistently repressing form switched their TPL-binding affinity and transcriptional and bio-logical roles in auxin *** on these data,we propose a model whereby competition between homologous repressors with different co-repressor-binding affinities could generate a bimodal output at thetranscriptional anddevelopmental levels.

关键词： auxin Aux/IAA dose-dependent regulation root hair transcription TOPLESS(TPL)

Ex situ aging effect on sulfonated poly(ether ether ketone) membrane:Hydration-dehydration cycling and hydrothermal treatment

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Journal of Energy Chemistry 2022年第7期31卷 583-592,I0014页

作者： seung-Young choi Kyeong Sik Jin Polymer&Materials Chemistry Department of ChemistryLund UniversitySE-22100Sweden Center for Hydrogen·Fuel Cell Research Korea Institute of Science and Technology(KIST)Seoul 02792Republic of Korea Pohang Accelerator Laboratory Pohang University of Science and Technology(POSTECH)PohangKyungbuk 37673Republic of Korea

Prolonged hydrothermal treatment for sulfonated poly(ether ether ketone) membranes induces mechanical degradation and developing hydrophilic-hydrophobic phase separation, simultaneously. The enhanced phase separation provides incremental proton conductivity to the membranes, whereas mechanical degradation drastically reduces device stability. On this basis, we describe here the effects of two different ex situ aging processes on sulfonated poly(ether ether ketone) membranes: hydrationdehydration cycling and prolonged hydrothermal treatment. Both aged membranes exhibited enhanced phase separation under the hydrated conditions, as characterized by small angle X-ray ***, when the aged membranes were dried again, the nanostructure of the membranes aged via the hydration-dehydration cycling was recoverable, whereas that of the membranes aged via prolonged hydrothermal treatment was irreversible. Furthermore, the two differently aged membranes showed clear differences in thermal, mechanical, and electrochemical properties. Finally, we implemented both aged membranes in fuel cell application. The sample aged via hydration-dehydration cycling maintained its improved cell performance, whereas the sample aged via hydrothermal treatment showed drastically reduced cell performance after durability test for 50 h.

关键词： Sulfonated poly(ether ether ketone) Humidity cycle test Ex situ aging Proton exchange membrane Fuel cell

A digital application for implementing the ICD-11 traditional medicine chapter

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Journal of Integrative Medicine 2020年第6期18卷 455-458页

作者： seung-hoon choi Department of Life Convergence Graduate SchoolDankook UniversityYonginGyeonggi-do 16890Republic of Korea

On May 25,2019,the World Health Assembly approved the eleventh revision of the International Statistical Classification of Diseases and Related Health Problems(ICD-11),containing a chapter on traditional *** means that the traditional East Asian medicine(TEAM)is now officially recognized as a part of mainstream medical ***,the patterns presented in the ICD-11 traditional medicine chapter are only the tip of the iceberg of TEAM clinical practice,and it will be necessary to supplement and upgrade the *** order to implement this,objectification and standardization of TEAM must be premised,and grafting with proper modern science and technology is *** Identification and Prescription Expert-11(PIPE-11),which is a TEAM clinical decision support system,adopts vastly from clinical literature on pattern identification and the *** adopting the rule-based reasoning method,the way of diagnosis and prescription by a TEAM practitioner in actual clinical practice is implemented as it ***-11 could support to improve both the accuracy of medical diagnosis and the reliability of the medical treatment of TEAM in clinical *** the field of research,it might facilitate the usage for reliable reference for symptoms and signs retrieval and patient *** the field of education,it can provide a high level of training for learning pattern identification and prescription,and further be used to reinforce skills of diagnosis and prescription by providing self-simulation ***,PIPE-11 as a digital application is expected to support the traditional medicine chapter of ICD-11 to successfully contribute to the improvement of human health.

关键词： ICD-11 PIPE-11 Traditional medicine Clinical decision support system Formula Pattern

Aerosol-assisted rapid synthesis of SnS-C composite microspheres as anode material for Na-ion batteries

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Nano Research 2015年第5期8卷 1595-1603页

作者： seung Ho choi Yun Chan Kang Department of Materials Science and Engineering Korea University Anam-Dong Seongbuk-Gu Seou1136-713 Republic of Korea

SnS-C composite powders were prepared through one-pot spray pyrolysis for use as anode materials for Na-ion batteries. C microspheres with uniformly attached cubic-like SnS nanocrystals, which have an amorphous C coating layer, were formed at a preparation temperature of 900 ℃. The initial discharge capacities of the bare SnS and SnS-C composite powders at a current density of 500 mA·g^-1 were 695 and 740 mA·h·g^-1, respectively. The discharge capacities after 50 cycles and the capacity retentions measured from the second cycle of the bare SnS and SnS-C composite powders were 25 and 433 mA.h.g-1 and 5 and 89%, respectively. The prepared SnS-C composite powders with high reversible capacities and good cycle performance can be used as Na-ion battery anode materials.

关键词： tin sulfide anode material carbon composite sodium battery energy storage

Randomized clinical trial of a bladder neck plication stitch during robot-assisted radical prostatectomy

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Asian Journal of Andrology 2015年第2期17卷 304-308,I0011页

作者： seung-Kwon choi Sejun Park Hanjong Ahn Department of Urology University of Ulsan College of Medicine Asan Medical Center Seoul Korea Department of Urology University of Ulsan College of Medicine Ulsan University Hospital Utsan Korea

Urinary incontinence after robot-assisted radical prostatectomy （RARP） is one of the most bothersome complications affecting patients＇ daily lives. The efficacy of the bladder neck plication stitch technique in promoting an earlier return of continence was prospectively evaluated in 158 patients who underwent RARP for clinically localized prostate cancer by a single surgeon at our institute from March 2012 to January 2013. Patients were randomized 1：1 to undergo surgery with （n = 79） or without （n = 79） the bladder neck plication stitch, and their time to recovery from incontinence, defined as being pad free, was compared. Recovery from incontinence at 1, 3, and 6 months were observed in 22 （27.8%）, 42 （53.2%）, and 57 （72.2%） patients, respectively, treated with, and 23 （29.1%）, 47 （59.5%）, and 59 （74.7%） patients, respectively, treated without the bladder neck plication stitch, with no significant difference in time to recovery from incontinence between the two groups. Multivariate analysis showed that age, membranous urethral length and shape of the prostatic apex on magnetic resonance imaging were independent predictors of early recovery from urinary incontinence after RARP. The bladder neck plication stitch had no effect on time to recovery from postoperative urinary incontinence following RARR

关键词： prostatectomy prostatic neoplasms urinary incontinence urologic surgical procedures

Dyna-QUF:Dyna-Q based univector field navigation for autonomous mobile robots in unknown environments

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Journal of Central South University 2013年第5期20卷 1178-1188页

作者： VIET Hoang-huu choi seung-yoon CHUNG Tae-choong Department of Computer Engineering Kyung Hee University

A novel approach was presented to solve the navigation problem of autonomous mobile robots in unknown environments with dense obstacles based on a univector field method. In an obstacle-free environment, a robot is ensured to reach the goal position with the desired posture by following the univector field. Contrariwise, the univector field cannot guarantee that the robot will avoid obstacles in environments. In order to create an intelligent mobile robot being able to perform the obstacle avoidance task while following the univector field, Dyna-Q algorithm is developed to train the robot in learning moving directions to attain a collision-free path for its navigation. Simulations on the computer as well as experiments on the real world prove that the proposed algorithm is efficient for training the robot in reaching the goal position with the desired final orientation.

关键词： Dyna-Q mobile robot reinforcement learning univector field

Three-dimensional porous graphene-metal oxide composite microspheres： Preparation and application in Li-ion batteries

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Nano Research 2015年第5期8卷 1584-1594页

作者： seung Ho choi Jung-Kul Lee Yun Chan Kang Department of Materials Science and Engineering Korea University Anam-Dong Seongbuk-Gu Seou1136-713 Republic of Korea Department of Chemical Engineering Konkuk University 1 Hwayang-Dong Gwangjin-Gu Seou1143-701 Republic of Korea

The use of new three-dimensional （3D） porous graphene-metal oxide composite microspheres as an anode material for Li-ion batteries （LIBs） is first introduced here. 3D graphene microspheres are aggregates of individual hollow graphene nanospheres composed of graphene sheets. Metal oxide nanocrystals are uniformly distributed over the graphene surface of the microspheres. The 3D porous graphene-SnO2 microspheres are selected as the first target material for investigation because of their superior electrochemical properties. The 3D porous graphene-SnO2 and graphene microspheres and bare SnO2 powders deliver discharge capacities of 1,009, 196, and 52 mAh·g^-1, respectively, after 500 cycles at a current density of 2 A·g^-1 .The 3D porous graphene-SnO2 microspheres exhibit uniquely low charge transfer resistances and high Li-ion diffusivities before and after cycling.

关键词： graphene metal oxide nanostructures electrode material batteries

Forecasting promising technology using analysis of patent information:Focused on next generation mobile communications

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Journal of Central South University 2014年第11期21卷 4303-4310页

作者： choi seung-Wook YOU Yen-Yoo NA Kwan-Sik Department of Knowledge Service & Consulting Hansung UniversitySeoul Korea Department of Management Information Systems Seowon UniversityCheongju Korea

In order to forecast promising technologies in the field of next generation mobile communication, various patent indicators were analyzed such as citation per patent, patent family information, patent share, increase rate, and patent activity. These indicators were quantified into several indexes and then integrated into an evaluation score to provide promising technologies. As a result of the suggested patent analysis, four technologies out of twenty two in details classification were selected, which showed outstanding technology competitiveness, high patent share and increasing rates as well as high recent-patent-ratios and triad-patent-family-ratios. Each of the selected technologies scored more than 10 points in total, and the following four technologies were suggested as promising ones in the field of next generation mobile communication: 1) 3GPP based mobile communication, 2) beyond 4G mobile communication, 3) IEEE 802.16 based mobile communication, which are in medium classification of broadband mobile communication system, and 4) testing/certification system of mobile communication, which is in medium classification of mobile communication testing/certification system.

关键词： next generation mobile communication promising technology forecasting patent information patent analysis patent indicators

Depth perception on fundus images using a single-channel stereomicroscopy

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Journal of Innovative Optical Health Sciences 2021年第3期4卷 68-76页

作者： Edalat Radfar Hyunseon Yu Tien Son Ho seung Ho choi Byungjo Jung Department of Biomedical Engineering Yonsei University Wonju-siGangwon-do 26493 Republic of Korea Research Center for Science and Technology in Medicine Tehran University of Medical Sciences Tehran 14185-615Iran Institute of Metabolism and Systems Research University of Birmingham Edgbaston Birmingham B152TTUK

Typical fundus photography produces a two-dimensional *** makes it difficult to observe the microvascular and neural abnormalities,because the depth of the image is *** provide depth appreciation,we develop a single-channel stereoscopic fundus video imaging sys-tem based on a rotating *** respect to the pupil center,the rotating refractor laterally displaces the optical path and the *** allows standard monocular fundus cameras to generate stereo-parallax and image disparity through sequential image *** opti-mize our imaging system,characterize the stereo-base,and image an eyeball model and a rabbit *** virtual realities are considered,our imaging system can be a simple yet efficient technique to provide depth perception in a virtual space that allows users to perceive abnor-malities in the eye fundus.

关键词： Imaging systems ophthalmic optics and devices refraction vision-binocular and stereopsis