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Fast infrared light source with a constructor of silicon micro-bridge

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Fast infrared light source with a constructor of silicon mic...

Photonics Asia 2004;Sensors and Imaging

作者： setsuo Kodato Anlitsu Company Tokyo Japan

This paper introduces a new type of infrared light source constructed by silicon micro-bridge manufactured on silicon substrate using MEMS technique. Electric current flowing through the micro-bridge makes its temperature goes up and radiates infrared light as traditional lamp. A simulation of characteristics of the infrared standard source calculated by finite element method is consistent with the test value. The radiation power, depending on micro-bridge size, is obtained from 1mW to 500 mW. The infrared light source can use electric chopping instead of mechanical chopping as traditional lamp for it's fast response time with typical 4 ms.

关键词： MEMS, infrared light source, chopping, silicon micro-bridge

Mechanical Properties of Ultra Fine Grained Iron and Steel

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Mechanical Properties of Ultra Fine Grained Iron and Steel

第五届国际低合金高强度钢会议暨第三届国际超细晶粒钢会议

作者： setsuo Takaki Faculty of Engineering Kyushu University Japan

The grain size dependence of yield stress is well known as so-called Hall-Petch relation and it has been confirmed that alinear relationship is realized up to 0.2μm for bulky iron. The grain size of 0

关键词： Ultra fine grain Iron Steel Hall-Petch relation Ductile-Brittle transition

Central Conservative Forces and Orbits beyond Conic Sections

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Journal of Mathematics and System Science 2014年第8期4卷 579-585页

作者： Haiduke Sarafian Masataka Kaneko setsuo Takato Pennsylvania State University Commonwealth College York PA USA Toho University Department of Pharmacology Funabashi Japan

The well-known characteristics of orbitals of classic central conservative force stems from the forces in proportion to the inverse square distance. In this article the authors extend the scope of the interest to central forces that are in proportion to algebraic integer powers of distance. Specifically, we investigate cases where the power of the distance varies between -2 to 4. Within this range the classic conic sections are associates with n = -2. The equation of motion leading to the orbitals only for n = I and -2 are analytically solvable. The remaining cases are analytically unsolvable nonlinear differential equations. Utilizing Computer Algebra System （CAS） we solve these equations numerically. For certain values of n numeric solutions are conducive to unseen trajectories.

关键词：曲线轨道保守力圆锥中央非线性微分方程计算机代数系统代数整数功率变化

Response evaluation of a compact and highly efficient neutron diffractometer for compact accelerator neutron sources

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辐射防护 2020年第6期40卷 540-544页

作者： Sho Imai Kenichi Watanabe Astushi Yamazaki Sachiko Yoshihashi Akira Uritani Seiji Tasaki setsuo Satoh Nagoya University Furo-choChikusa-kuNagoya464-8603Japan Kyoto University YoshidahonmachiSakyo-kuKyoto606-8501Japan High Energy Accelerator Research Organization Oh-hoTsukuba305-0801Japan

We fabricated the spheroid neutron diffractometer with 79 neutron detector rings using the transparent rubber sheet type Eu:LiCaAlF6 scintillators and wavelength-shifting *** confirmed that the fabricated detector shows a clear neutron peak and can discriminate neutron and gamma-ray events in a signal pulse *** additionally checked that the fabricated diffractometer can detect a neutron diffraction peak of ferrite powder at Kyoto University Accelerator-driven Neutron ***,it can be expected that crystal structural analysis will be possible even by small accelerator neutron sources.

关键词： TRUST Eu:LiCAF scintillator neutron diffractometer neutron detector time-of-flight KUANS LiTA12

Synchronous rectal and esophageal cancer treated with chemotherapy followed by two-stage resection

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World Journal of Clinical Cases 2013年第2期1卷 87-91页

作者： setsuo Utsunomiya Keisuke Uehara Takuya Kurimoto Ken Hirose Masahide Fukaya Yu Takahashi Yoshiro Taguchi Keita Itatsu Masato Nagino Department of Gastrointestinal Oncology Nagoya Kyoritsu Hospital Division of Surgical Oncology Department of Surgery Nagoya University Graduate School of Medicine Department of Gastroenterology Nagoya Kyoritsu Hospital

We report a case of 61-year-old male who had synchronous advanced rectal cancer involving the urinary bladder massively associated with multiple liver metastases, and esophageal cancer successfully treated by neoadjuvant chemotherapy followed by two-stage resection. Although complete resection of each of the lesions was considered possible by performing anterior pelvic exenteration, liver resection, and esophagectomy, it might be impossible for the patient to endure the stress of all of these operative procedures at once. Therefore, we planned to perform staged treatment with prioritizing consideration. First, we instituted chemotherapy with the FOLFOX(oxaliplatin + fluorouracil + leucovorin) plus cetuximab regimen, which could adequately control both rectal and esophageal cancer. After 6 cycles of chemotherapy, high anterior resection combined with cystoprostatectomy and lateral segmentectomy plus partial hepatectomy was performed followed by staged esophagectomy with three-field lymph node dissection. It was possible to use oxaliplatin and cetuximab safely as neoadjuvant therapy not only for advanced rectal cancer but for esophageal cancer, and it was effective.

关键词： Rectal cancer Esophageal cancer Neoadjuvant chemotherapy Cetuximab Oxaliplatin

Limit of Dislocation Density and Ultra-Grain-Refining on Severe Deformation in Iron

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Limit of Dislocation Density and Ultra-Grain-Refining on Sev...

第二届先进钢铁结构材料国际会议

作者： setsuo Takaki Toshihiro Tsuchiyama Dept.of Materials Science and Engineering Kyushu University6-10-1 Hakozaki Higashi-ku Fukuoka 812-8581 Japan Dept.of Materials Science and Engineering Kyushu University6-10-1 Hakozaki Higashi-ku Fukuoka 812-8581 Japan

＜正＞It is well-known that severe deformation to metals causes a direct grain refinement of the matrix without special heat-treatments due to the mechanism of dynamic continuous recrystallization （DCR）. However, the microstructural revolution during severe deformation is seemed to be different depending on the deformation mode, namely the direction of deformation. In general, multi-directional deformation is thought to be effective for the grain refinement caused through DCR. For instance, ultra-grain-refinement to 10nm has already achieved by mechanical milling treatment in a steel powder and hardness of the mechanically milled steel powder is increased to around HV12GPa by such a marked grain refinement. On the other hand, hardness of iron never exceeds HV4GPa by the mode of uni-directional deformation such a conventional cold rolling. In this paper, a limit of dislocation density is discussed for iron which is severely strained by the mode of uni-directional deformation, and also the importance of multi-directional deformation on DCR will be mentioned in association with a significant work hardening behavior in mechanicallv milled iron powder.

关键词： grain refinement multi-directional deformation dislocation density grain size dynamic continuous recrystallization

High Grade Bloom Continuous Casting Technology by NIPPON STEEL ENGINEERING

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High Grade Bloom Continuous Casting Technology by NIPPON STE...

第八届（2011）中国钢铁年会

作者： Kittaka setsuo Miura Yasuaki Continuous Caster ＆ Rolling Mill Engineering Gr. NIPPON STEEL ENGINEERING CO.LTD.

Special alloy steel is widely used for the bearings and structural parts for the automobile, the office automation equipment and home electronics. NIPPON STEEL ENGINEERING CO.,LTD（NSEC）. started up first continuous caster for the special alloy steel in 1977. Since then, NSEC have been highly appreciated by special steel industry and have supplied the bloom continuous casters which applied a number of innovative technology to the special steel manufacturer and the integrated iron and steel manufacturer all over the world including Nippon Steel Corporation. In Japan before 1980, the special alloy steel was mainly produced by the vertical type bloom continuous caster in order to reduce the inclusions and the pinholes of bloom. However, the vertical type bloom continuous caster has many problems such as low productivity, expensive construction cost and difficult maintenance. In 1982, NSEC developed and supplied the large radius type large section bloom caster which can produce the special alloy steel for the automobile parts and the bearing, etc and can improve the productivity, the bloom internal and surface quality and the production yield. NSEC’s large radius type large section bloom caster has a number of advantages. Some of the advantages on bloom quality improvements are:（1）Reduction of the surface and internal cracks and internal inclusion thanks to Optimum Roll Profile Engineering.（2）Reduction of the surface cracks thanks to High Accuracy Mold Oscillation, Uniform Secondary Cooling and Bloom Surface Uniform Quenching.（3）Improvement of the center segregation thanks to Tundish Plasma Heater and Optimum Soft Reduction.（4）Decrease of the surface inclusions and pinholes thanks to Optimum M-EMS.（5）Decrease of the center porosity thanks to Innovative Equipment. All the above technology can be applied to new or existing bloom casters supplied not only by NSEC but also by other caster suppliers.

关键词： Special alloy steel,Large radius type large section bloom caster,Tundish plasma heater,M-EMS Soft reduction

Low-Loss Co<sub>2</sub>-Y Ferrites with Added CuO Sintered in Air for High Frequency Application

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Materials Sciences and Applications 2014年第13期5卷 984-989页

作者： Shigeo Fujii Koji Wakamatsu Hiroshi Satoh setsuo Yamamoto Department of Material Science and Engineering University of Yamaguchi Ube Japan

The sintering characteristics of hexagonal Co2-Y-type ferrite, Ba2Co2Fe12O22, with the addition of 0.6 wt% CuO, were studied in order to allow for preparation in air, as opposed to the conventionally recommended O2, for industrial production. The dependence of the resistivity, ρ magnetic loss, tanδ, and the permeability, μ, at 1 GHz on the sintering temperature was investigated. A low tanδ of 0.05 with a m of 2.7 at a frequency of 1 GHz, along with a high ρ (up to 7 × 104 μm), were attained under sintering at 1170°C in air, which were the same features as those of samples sintered at 1200°C in O2. The dependence of tanδ on grain diameter was also examined, and it was determined that a small grain size (less than 2 μm) is preferable for low tanδ.

关键词： Ferrite Hexagonal Y-Type Sintering Low Loss

Safety, Tolerability, and Pharmacokinetics of E3030, a Novel Peroxisome Proliferator-Activated Receptor <i>α/γ</i>Dual Agonist, in Healthy Japanese Male Subjects

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Pharmacology & Pharmacy 2014年第2期5卷 139-148页

作者： Yutaka Takeuchi Yuki Nishioka Yasumi Kitahara setsuo Hasegawa Akihiro Ohnishi Clinical Development Japan/Asia Clinical Research PCU Eisai Co. Ltd. Tokyo Japan Department of Laboratory Medicine Daisan Hospital Jikei University School of Medicine Tokyo Japan Japan Regulatory Affairs Global Regulatory CFU Eisai Co. Ltd. Tokyo Japan Sekino Clinical Pharmacology Clinic Tokyo Japan Present address: Pharmaspur Inc. Tokyo Japan

Objective: The objectives of the present study were to evaluate the safety of single oral dose E3030 in healthy Japanese male subjects, and to evaluate pharmacokinetics after single oral dose E3030 and food effect on pharmacokinetic profiles. Methods: This study was conducted in a randomized, double-blind, placebo-controlled, ascending single-dose study in 56 healthy Japanese male subjects. Subjects were orally administered E3030 (0.5-40 mg) or placebo. Results: Six of 42 (14%) subjects’ administered E3030 experienced adverse events;however, all adverse events were mild and transient, and there was no dose-dependent increase in any adverse event. Plasma samples were collected over 96 hours after dosing. After administration in the fasted state, Cmax of E3030 was achieved between 1.00 and 1.75 hours, indicating rapid absorption. Both Cmax and AUC were dose-proportional in the range of 0.5 to 40 mg. The average range of elimination half-life was 18.4-23.8 hr. CL/F and Vz/F also remained nearly constant regardless of dose levels. In addition, food effect was exploratorily evaluated in five subjects of administered E3030 (10 mg) in both fasted and fed states. The fed/fasted ratios for the geometric mean of the Cmax and AUC were 0.803 and 0.913, respectively. Conclusion: E3030 was safe and well tolerated at single doses up to 40 mg. The pharmacokinetic profile showed good linearity, and food effect on pharmacokinetics of E3030 was not significant.

关键词： PPAR Agonist Phase 1 Pharmacokinetics Healthy Subjects