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A Comprehensive Review of Animal Models for Coronaviruses: SARSCoV-2, SARS-CoV, and MERS-CoV

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Virologica Sinica 2020年第3期35卷 290-304页

作者： Ashutosh Singh Rahul Soloman Singh Phulen sarma Gitika Batra Rupa Joshi Hardeep Kaur Amit Raj Sharma Ajay Prakash Bikash Medhi Department of Pharmacology Postgraduate Institute of Medical Education and ResearchChandigarh 160012India

The recent outbreak of coronavirus disease(COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) has already affected a large population of the world. SARS-CoV-2 belongs to the same family of severe acute respiratory syndrome coronavirus(SARS-CoV) and Middle East respiratory syndrome coronavirus(MERSCoV). COVID-19 has a complex pathology involving severe acute respiratory infection, hyper-immune response, and coagulopathy. At present, there is no therapeutic drug or vaccine approved for the disease. There is an urgent need for an ideal animal model that can reflect clinical symptoms and underlying etiopathogenesis similar to COVID-19 patients which can be further used for evaluation of underlying mechanisms, potential vaccines, and therapeutic strategies. The current review provides a paramount insight into the available animal models of SARS-CoV-2, SARS-CoV, and MERS-CoV for the management of the diseases.

关键词： Coronaviruses SARS MERS COVID-19 Animal model

Diversity of endophytic fungi associated with Hedychium spicatum Ham ex *** their antifungal activity against the phytopathogen Alternaria solani

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Studies in Fungi 2020年第1期5卷 84-93页

作者： sarma P Dkhar MS Kayang H Kumar M Dubey NK Raghuwanshi R Microbial Ecology Laboratory Department of BotanyNorth Eastern Hill UniversityShillong793022 Department of Botany Banaras Hindu UniversityVaranasi221005 Department of Botany Mahila MahavidyalayaBanaras Hindu UniversityVaranasi221005

Twenty eight strains of endophytic fungi including sterile mycelia were isolated from the leaf,rhizome and roots of Hedychium spicatum Ham *** of the endophytic fungi isolated belonged to the phylum Ascomycota which accounted of about 84%.The endophytic assemblage was dominated by the class *** fungal genera such as Fusarium and Penicillium were found to be common to all the plant *** of endophytic fungi was found to be highest in the roots(H’=2.43).Mucor hiemalis,Penicillium sp.,Penicillium expansum,***,Phoma medicaginis,Trichoderma *** *** showed above 60%inhibition against the phytopathogen Alternaria solani.

关键词： Colonization frequency diversity index percentage inhibition

Performance Comparison of a QoS Aware Routing Protocol for Wireless Sensor Networks

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Communications and Network 2016年第1期8卷 45-55页

作者： Bhaskar Bhuyan Nityananda sarma Department of IT Sikkim Manipal Institute of Technology Rangpo India Department of Computer Science and Engineering Tezpur University Napaam India

Quality of Service (QoS) in Wireless Sensor Networks (WSNs) is a challenging area of research because of the limited availability of resources in WSNs. The resources in WSNs are processing power, memory, bandwidth, energy, communication capacity, etc. Delay is an important QoS parameter for delivery of delay sensitive data in a time constraint sensor network environment. In this paper, an extended version of a delay aware routing protocol for WSNs is presented along with its performance comparison with different deployment scenarios of sensor nodes, taking IEEE802.15.4 as the underlying MAC protocol. The performance evaluation of the protocol is done by simulation using ns-2 simulator.

关键词： Wireless Sensor Networks Quality of Service Delay Time Constraint

Statistically Convergent Difference Double Sequence Spaces

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Acta Mathematica Sinica,English Series 2008年第5期24卷 737-742页

作者： Binod Chandra TRIPATHY Bipul sarma Mathematical Sciences Division,Institute of Advanced Study in Science and Technology,Paschim Boragaon Garchuk Guwahati- 781 035 India Mathematical Sciences Division Institute of Advanced Study in Science and Technology Paschim Boragaon Garchuk Guwahati India

In this article we define the notion of statistically convergent difference double sequence spaces. We examine the spaces 2l∞（△, q）, 2c（△, q）, 2cB（△, q）, 2cR（△, q）, 2cBR（△,q） etc. being symmetric, soli... 详细信息

关键词： difference sequence statistical convergence completeness solid space symmetric

Application of RP-HPLC method in dissolution testing and statistical evaluation by NASSAM for simultaneous estimation of tertiary combined dosages forms

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Journal of Pharmaceutical Analysis 2015年第5期5卷 307-315页

作者： Yogesh Upadhyay Nitin Sharma G.S.sarma Ravindra K.Rawal Department of Pharmaceutical Analysis Indo-Soviet Friendship College of Pharmacy

A dissolution method with robust high performance liquid chromatographic （HPLC） analysis for im- mediate release tablet formulation was developed and validated to meet the requirement as per Inter- national Conference on Harmonization （ICH） and United States Food and Drug Administration （USFDA） guidelines. The method involved the use of Agilent ZORBAX Eclipse XDB C18 column, and temperature was maintained at 30 ℃. After optimization, the mobile phase was selected as phosphate buffer （KH2PO4, 30 mM）： ACN （60：40, v/v） with pH 3.0, and retention time Rt was found as 3.24, 4.16, and 2.55 min for paracetamol （PCM）, chlorpheniramine maleate （CPM） and phenylephrine hydrochloride （PH） respec- tively at 265 nm and at a flow rate of 1 mL/min. The relative standard deviation （%RSD） for 6 replicate measurements was found to be less than 2%. Furthermore net analyte signal standard addition method （NASSAM） with spectrophotometer was performed for standard and liquid oral suspension. On the basis of selectivity, sensitivity and accuracy analysis, it was confirmed that this novel method could be useful for simultaneous estimation of the given drug combinations. Two-way analysis of variance （ANOVA） was applied for evaluating the statistical difference between the assay results obtained via both NASSAM and RP-HPLC methods and ultimately no significant difference was found between both the methods. All the methods and results were acceptable and confirmed that the method was suitable for intended use.

关键词： DissolutionRP-HPLCNet analyte signal standard addition meth-odTwo-way ANOVA

Growth and Inhibition of Equatorial Anomaly Prior to an Earthquake (EQ): Case Studies with Total Electron Content (TEC) Data for Major EQs of Japan 2011 and Indonesia 2012

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Positioning 2013年第3期4卷 240-252页

作者： Minakshi Devi Alaka Medhi Arup Jyoti Dev sarma sarma Ananda Kumar Barbara Department of Physics Gauhati University Guwahati India.

The processes leading to the growth and inhibition of equatorial anomaly before major earthquake (EQ) were viewed in this paper by examining global Total Electron Content (TEC) that contoured over longitude sectors covering Africa to Pacific, in association with EQ events of Japan (M = 9) that occurred at 135°E to 145°E and 35°N to 40°N, on March 9 and 11, 2011 and of Indonesia (M = 8.6) that took place at 2.311°N, 93°E, in April 11, 2012. The paper focuses on the development of abnormal increase in density in the night sector around—10° latitude zone prior to the two major EQ events, though their epicenters are separated widely from the anomaly region. The F-layer density variations from relevant locations and TEC features obtained from GPS at Appleton anomaly crest station are utilized as supporting inputs. The possible sources leading to the anomalous development in density are discussed in the frame of EQ time consequences of lithospheric-atmospheric processes between the equator and beyond. The role of electric field generated by pre EQ preparatory activities and dynamical coupling modes through seismic fault line are brought in to the ambit of discussion.

关键词： TEC Global Earthquake Equatorial Anomaly F-Layer Density

Quality of Service (QoS) Provisions in Wireless Sensor Networks and Related Challenges

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Wireless Sensor Network 2010年第11期2卷 861-868页

作者： Bhaskar Bhuyan Hiren Kumar Deva sarma Nityananda sarma Avijit Kar Rajib Mall 不详

Wireless sensor networks (WSNs) are required to provide different levels of Quality of Services (QoS) based on the type of applications. Providing QoS support in wireless sensor networks is an emerging area of research. Due to resource constraints like processing power, memory, bandwidth and power sources in sensor networks, QoS support in WSNs is a challenging task. In this paper, we discuss the QoS requirements in WSNs and present a survey of some of the QoS aware routing techniques in WSNs. We also explore the middleware approaches for QoS support in WSNs and finally, highlight some open issues and future direction of research for providing QoS in WSNs.

关键词： Wireless Sensor Network Quality of Service Middleware Routing

Proton Coupled Redox Switching in an Annulated π-Extended Octaphyrin

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Proton Coupled Redox Switching in an Annulated π-Extended O...

Small x phenomenology on gluon evolution through the BFKL equation in light of a constraint in multi-Regge kinematics

中国化学会第五届卟啉与酞菁学术研讨会

作者： Tridib sarma Center for Supramolecular Chemistry ＆ Catalysis Shanghai University

＜正＞Proton coupled electron transfer（PCET） is an important chemical and biological phenomenon wherein,transfer of an electron is facilitated by transfer of a ***,we described that upon protonation,naphthorosarin,an annulated expanded porphyrin with 4 n π-electron antiaromatic character,undergoes reduction in the presence of halide anion sources to produce a [4 n+2] π-electron aromatic species via an intermediate [4 n+1] radical state.

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来源： cnki会议评论

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Communications in Theoretical Physics 2020年第2期72卷 50-59页

作者： Pragyan Phukan Madhurjya Lalung Jayanta Kumar sarma HEP laboratory Department of PhysicsTezpur UniversityIndia

We investigate the impact of so-called kinematic constraint on gluon evolution at small *** the constraint on the real emission term of the gluon ladder diagram,we obtain an integro-differential form of the Balitsky-Fadin-Kuraev-Lipatov(BFKL)*** we solve the equation analytically using the method of *** sketch the Bjorken x and transverse momentum kt2 dependence of our solution of unintegrated gluon distributions f(x,kt2)in the kinematic constraint supplemented BFKL equation and contrasted the same with the original BFKL *** we extract the integrated gluon density xg(x,Q2)from unintegrated gluon distributions f(x,kt2)and compared our theoretical prediction with that of global data fits,namely NNPDF3.1 sx and *** we illustrate the phenomenological implication of our solution for unintegrated gluon distribution f(x,kT2)towards exploring high precision HERA DIS data by the theoretical prediction of proton structure functions(F2 and FL).

关键词： parton evolution equation gluon distribution function perturbative QCD