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Financial Innovation 2021年第1期7卷 942-961页

作者： Öer depren Mustafa Tevfik kartal serpil kılıçdepren Yapıkredi Bank IstanbulTurkey Borsaİstanbul Financial Reporting and Subsidiaries Directorate Reşitpaşa Mahallesi Borsaİstanbul CaddesiNo:434467 IstanbulTurkey Department of Statistics Yildiz Technical UniversityIstanbulTurkey

Some countries have announced national benchmark rates,while others have been working on the recent trend in which the london Interbank Offered Rate will be retired at the end of *** that Turkey announced the Turkish lira Overnight Reference Interest Rate(TlREF),this study examines the determinants of *** this context,three global determinants,five country-level macroeconomic determinants,and the COVID-19 pandemic are considered by using daily data between December 28,2018,and December 31,2020,by performing machine learning algorithms and Ordinary least *** empirical results show that(1)the most significant determinant is the amount of securities bought by Central Banks;(2)country-level macroeconomic factors have a higher impact whereas global factors are less important,and the pandemic does not have a significant effect;(3)Random Forest is the most accurate prediction *** action by considering the study’s findings can help support economic growth by achieving low-level benchmark rates.

关键词： Benchmark rate Determinants Machine learning algorithms Turkey

Probabilistic Normed Riesz Spaces

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Acta Mathematica Sinica,English Series 2012年第7期28卷 1401-1410页

作者： Celaleddin SENCMEN serpil PEHlVAN Department of Mathematics Faculty of Arts and SciencesMehmet Akif Ersoy University Department of Mathematics Faculty of Arts and SciencesSüleyman Demirel University

In this paper, the concepts of probabilistic normed Riesz space and probabilistic Banach lattice are introduced, and their basic properties are studied. In this context, some continuity and convergence theorems are pr... 详细信息

关键词： Probabilistic normed Riesz space probabilistic Banach lattice order convergence strong convergence probabilistic norm Cauchy system

Impact of COVID-19 on the food supply chain

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Food Quality and Safety 2020年第4期4卷 167-180页

作者： serpil Aday Mehmet Seckin Aday Food Processing Department Vocational School of BigaCanakkale Onsekiz Mart UniversityBigaCanakkaleTurkey Food Engineering Department Engineering FacultyCanakkale Onsekiz Mart UniversityCanakkaleTurkey

A pandemic is not a new event encountered in the history of humanity because mankind has faced various pandemics in history. The common point of pandemics is their serious negative effects on the global economy. Considering the food supply chain, one of the most important sectors of the economy, it has been seen that COVID-19 has an impact on the whole process from the field to the consumer. In the light of recent challenges in food supply chain, there is now considerable concern about food production, processing, distribution, and demand. COVID-19 resulted in the movement restrictions of workers, changes in demand of consumers, closure of food production facilities, restricted food trade policies, and financial pressures in food supply chain. Therefore, governments should facilitate the movement of workers and agri-food products. In addition, small farmers or vulnerable people should be supported financially. Facilities should change the working conditions and maintain the health and safety of employees by altering safety measures. Food protectionist policies should be avoided to prevent an increase in food prices. In conclusion, each country must realize the severity of the situation and sometimes should tighten or loosen the measures according to the spread of the pandemic. The supply chain also should be flexible enough to respond to the challenges in the food supply chain. The purpose of this review is to evaluate the impact of COVID-19 on the agriculture and food sector and to summarize the recommendations required to reduce and control the effect of the pandemic.

关键词： pandemic COVID-19 agriculture food supply chain

Characterization of a newly identified Iipase from a lipase-producing bacterium

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Frontiers in Biology 2016年第4期11卷 323-330页

作者： serpil Ugras Sebnem Uzmez Department of Field Crops Faculty of Agriculture and Natural Science Duzce University 81620 Duzce Turkey Department of Biology Faculty of Arts and Sience Giresun University 28049 Giresun Turkey Department of Chemistry Sience Institute Duzce University 81620 Duzce Turkey

BACkGROUND： lipases differ from one another with respect to certain properties, and such differences can be very important for various industrial applications. Considering the rapidly developing nature of the relevant industries, there is a need for new lipases with characteristics differing from those of existing enzymes. METHODS： In this study, a bacterium was isolated from both the surface mucus layer and gills of rainbow trout （Oncorhynchus mykiss） from Giresun, Turkey. The bacterial species was identified based on its morphological and physiochemieal properties, and on its 16S rDNA sequence. The qualitative activity of the bacterial lipase was determined on Rhodamine B and Tween-20 agar plates. The lipase was partially purified from the supernatant of bacterial cultures, and then characterized. RESUlTS： The bacterial strain was identified as Acinetobacter sp. strain SU15. The enzyme from Asp-SU15 exhibits maximum activity toward p-nitrophenyl dodecanoate （C12） at 40℃ and pH 8.0. The specific activity of the lipase was calculated to be 10.059 U·l^-1. The molecular mass of the enzyme was determined to be -62 kDa via SDS-PAGE. However, native-PAGE indicated that the enzyme forms very large active aggregates, with molecular masses exceeding 250 kDa. The catalytic activity of the enzyme is enhanced in the presence of Co^2＋, Ca^2＋, and methanol, but is partially inhibited by Ni2＋, ethyl acetate, and ***： Further research could examine possible industrial applications for the lipase from Asp-SU15.

关键词： Acinetobacter sp. lipase Oncorhynchus mykiss SDS-PAGE

Ground state energy of He isoelectronic sequence treated variationally via Hylleraas-like wavefunction

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Chinese Physics B 2009年第6期18卷 2238-2243页

作者： serpil Sakiroglu kadir Akgngr Ismail Skmen Physics Department Dokuz Eyll University

In this study, the energy for the ground state of helium and a few helium-like ions （Z=1-6） is computed variationally by using a Hylleraas-like wavefunction. A four-parameters wavefunction, satisfying boundary conditions for coalescence points, is combined with a Hylleraas-like basis set which explicitly incorporates r12 interelectronic distance. The main contribution of this work is the introduction of modified correlation terms leading to the definition of integral transforms which provide the calculation of expectation value of energy to be done analytically over single-particle coordinates instead of Hylleraas coordinates.

关键词： He isoelectronic sequence Hylleraas basis set electronic correlation variational method

Idiopathic hirsutism:Is it really idiopathic or is it misnomer?

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World Journal of Clinical Cases 2023年第2期11卷 292-298页

作者： kursad Unluhizarci Aysa Hacioglu serpil Taheri Zuleyha karaca Fahrettin kelestimur Department of Endocrinology Erciyes University Medical SchoolKayseri 38039Turkey Department of Medical Biology Erciyes University Medical SchoolKayseri 38039Turkey Department of Endocrinology Yeditepe University Medical SchoolIstanbul 34755Turkey

Hirsutism,which is characterized by excessive growth of terminal hair in a male pattern,may result from various causes including polycystic ovary syndrome(PCOS),non-classic congenital adrenal hyperplasia,adrenal or ovarian tumors or it may be *** hirsutism is currently defined as hirsutism associated with normal ovulatory function,normal serum androgen levels and normal ovarian morphology,however,the pathogenesis of idiopathic hirsutism is not *** androgens are the main hormones to stimulate growth of body hair,therefore,there should be any form of increased androgen effect irrespective of normal serum androgen levels in any patient with *** accordance to this scientific truth,we have previously shown that,although within normal limits,patients with idiopathic hirsutism have relatively higher serum androgen levels(relative hyperandrogenemia)in comparison to healthy subjects which let as to think that is idiopathic hirsutism really idiopathic?In addition to relative hyperandrogenemia,we have previously shown that,in comparison to healthy subjects,women with idiopathic hirsutism demonstrated higher expression of steroid sulphatase and 17-beta hydroxysteroid dehydrogenase mRNA both in the subumbilical region and arm skin,which contributes to local androgen *** results support the idea that,in some patients,although the adrenals or ovaries do not secrete increased amount of androgens leading to hyperandrogenemia,pilocebaceous unit locally produce increased amount of androgens leading to hirsutism without ovulatory *** the demonstration of relative hyperandrogenemia and possible increase in local androgen synthesis in patients with idiopathic hirsutism,we think that idiopathic hirsutism is not idiopathic and it may be named as“normoandrogenic hirsutism”.Furthermore,it may not be a different entity but may be an early stage of hyperandrogenic disorders such as ***,this can be find out by following-up p

关键词： Idiopathic hirsutism Normoandrogenic hirsutism Hyperandrogenemia Androgen excess disorders

Determination of the Relationship between Empathy and Compassion Fatigue in Pediatric Clinic Nurses

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International Journal of Mental Health Promotion 2024年第11期26卷 935-942页

作者： Dilek Akıncı HacerÇetin serpil Yılmaz Pediatric Intensive Care Clinic Mersin University HospitalMersin UniversityMersin33110Türkiye Faculty of Nursing Mersin UniversityMersin33110Türkiye Faculty of Health Sciences Hitit UniversityÇorum19200Türkiye

Background:This study aimed to determine the relationship between compassion fatigue and empathic disposition and skill levels of pediatric clinic ***:This research was carried out as a descriptive and cross-sectional *** research was carried out with 233 nurses determined by using a stratified sampling method from 648 nurses working in two University Hospital and two City Hospital children’s *** were collected using the“Personal Information Form”,“Compassion Scale(CS)”,“Empathic Tendency Scale(ETS)”and“Empathic Skill Scale(ESS)”.Pearson Correlation test,Student’s t-test,ANOVA test,and Scheffe test were used in the analysis of the ***:The mean age of the nurses participating in the study was 30.93±6.23 years,81.1%were women and 54.9%were *** clinic nurses’mean compassion score was 96.29±11.64,empathic tendency mean score was 69.30±8.39,and empathic skill mean score was 140.82±*** to the findings obtained,the mean compassion score of the male,married,and nurses who were not satisfied with working in the pediatric clinics and working in the pediatric emergency clinics was found to be the lowest(pking in the pediatric inpatient clinics,who were satisfied with working in the pediatric clinic,and who did not have the thought of moving to another clinic,were found to be significantly higher(pkills of nurses working only during the daytime were found to be significantly higher(plusion:This study confirms that pediatric clinic nurses are experiencing compassion fatigue at the end of COVID-19 and how this situation negatively affects their empathic tendencies and *** study highlights the need for both clinical and management-based planning to prevent compassion fatigue and increase empathic tendencies and skills in Pediatric clinic nurses.

关键词： Pediatric clinic compassion fatigue empathy nursing care

linear Mixed Model Analysis of Worldwide longitudinal Infant Mortality Rate Data and Association with Human Development Index

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Journal of Mathematics and System Science 2013年第4期3卷 173-179页

作者： serpil Aktas Department of Statistics Hacettepe University Ankara Beytep 06800 Turkey

A linear mixed model is used to determine the explaining infant mortality rate data of United Nations countries. The HDI （human development index） has a significant negative linear relationship with infant mortality rate. United Nations data shows that the infant mortality rate has a descending trend over the period 1990-2010. This study aims to assess the value of the HDI as a predictor of infant mortality rate. Findings in the paper suggest that significant percentage reductions in infant mortality might be possible for countries for controlling the HDI.

关键词： Infant mortality rate human development index linear mixed models

Conventional and microwave irradiated synthesis,biological activity evaluation and molecular docking studies of highly substituted piperazine-azole hybrids

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Chinese Chemical letters 2017年第5期28卷 995-1005页

作者： Arif Mermer serpil Demirci Serap Basoglu Ozdemir Ahmet Demirbas Serdar Ulker Faik Ahmet Ayaz Fatma Aksakal Neslihan Demirbas karadeniz Technical University Department of ChemistryTrabzon 61080Turkey Giresun University School of Applied ScienceDepartment of Crop Production and TechnologyGiresun 28000Turkey Recep Tayyip Erdogan University Department of BiologyRize 53100Turkey karadeniz Technical University Department of BiologyTrabzon 61080Turkey Department of Chemistry Faculty of ScienceGebze Technical UniversityKocaeli 41400Turkey

Azole derivatives（3,6） obtained starting from 1-（2-methoxyphenyl） piperazine were converted to the corresponding Mannich bases containing β-lactame or flouroquinolone core via a one pot three component *** synthesis of conazole analogues was carried out starting from triazoles by three *** were carried out under conventional and microwave mediated *** the newly synthesized compounds were screened for their antimicrobial,enzyme inhibition and antioxidant activity,and most of them displayed good-moderate *** affinities and non-covalent interactions between enzyme-ligand complexes were predicted with molecular docking method at molecular *** results complemented well the experimental results on α-glucosidase and urease inhibitory effects of the *** binding affinities and much more interaction networks were observed for active compounds in contrary to inactive *** was predicted with the docking studies that triazole and anisole moieties in the structure of the synthesized compounds contributed to the stabilization of corresponding enzymes through noncovalent interactions.

关键词： Fluoroquinolone 1 2 4-Triazole Microwave Mannich reaction Biological activity Molecular docking

The Interaction and life Experiences between the Patient and the Nurse Caring for the Patient with COVID-19 in Turkey: A Qualitative Dyadic Approach

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International Journal of Mental Health Promotion 2022年第4期24卷 511-525页

作者： Nuran Dudaklı Hilal Altundal Duru Mualla Yılmaz serpil Türkleş Department of Psychiatric Service Mersin City Training and Research HospitalMersin33240Turkey Department of Mental Health Nursing Faculty of NursingMersin UniversityMersin33343Turkey

Previous research and observations have shown that COVID-19 affected both patients’and nurses’mental *** in the best times,one of the best ways to improve patients’experiences is to improve the health workers’***,it is important to be aware of the patterns of interaction between patients diagnosed with COVID-19 and the nurses caring for them and to help them recognize the strengths of their *** this study,we aimed that purposed to discover the interaction and life experiences between the COVID-19 patients and the nurses who provided care for them in *** the dyadic approach,a qualitatively descriptive design has been *** research examples consisted of 12 patients diagnosed with COVID-19 selected by purposeful exempliﬁcation and 12 nurses who provided care to ***-structured individual in-depth interviews were conducted with *** study adheres to the COREQ *** a result of the content analysis,four main themes came forward:life change,pandemic journey,getting strong together,new *** should focus on appropriate psychological interventions in order to fortify the relations and mental health of dyad *** should focus on appropriate psychological interventions in order to fortify the relations and mental health of dyad *** our research,it is expected to guide related public institutions and non-governmental organizations on formulating policies related to protecting and maintaining the mental health of nurses and patients,extending the scope of existing information,providing patient-health worker security,to assess the problems on theﬁeld through the eyes of patients-health workers and to take necessary *** study,which deals with the interaction and life experiences of patients with COVID-19 and nurses who care for them,will shed light on patients,families,communities,organizations,health policies and systems.

关键词： COVID-19 patient nursing qualitative methodology dyadic approach