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Frontiers of Structural and Civil Engineering 2024年第5期18卷 743-759页

作者： serkan ETLI Department of Civil Engineering Kahramanmaras Sutcu Imam UniversityKahramanmaraş46040Turkey

It is known that clay-based building materials such as bricks and tiles accumulate in landfills at the end of their useful *** an alternative,recycling clay-based building material can reduce the negative environmental *** brick powder(RBP)is obtained by grinding waste brick and tile collected from end-of-life *** the scope of the study,the use of self-compacting fiber reinforced mortars(SCFRMs)produced with RBP using CEM-I 42.5R and 52.5R class cements for two different cement classes was *** accordance with EFNARC,a water binding ratio of 0.42 was used to control the workability and strength of the *** the produced SCFRM,1%,2%,and 3%by weight binder Polypropylene(PP)fiber was added to the blends with 10%,20%,and 30%RBP substitutes.A total of 32 SCFRM mixes were produced and *** flexural and compressive strengths at 7,28,56,and 90 d were evaluated on the produced *** addition,porosity and water absorbency values were examined since these are significant for durability *** was observed that the use of RBP increases durability,and the use of fiber can have positive effects in terms of both durability and strength.

关键词： cement strength tile/brick dust self-compacting fiberized mortar

Developmental regulation of neuronal gene expression by Elongator complex protein 1 dosage

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Journal of Genetics and Genomics 2022年第7期49卷 654-665页

作者： Elisabetta Morini Dadi Gao Emily M.Logan Monica Salani Aram J.Krauson Anil Chekuri Yei-Tsung Chen Ashok Ragavendran Probir Chakravarty serkan erdin Alexei Stortchevoi Jesper Q.Svejstrup Michael E.Talkowski Susan A.Slaugenhaupt Center for Genomic Medicine Massachusetts General Hospital Research InstituteBostonMAUSA Department of Neurology Massachusetts General Hospital Research Institute and Harvard Medical SchoolBostonMAUSA Program in Medical and Population Genetics and Stanley Center for Psychiatric Research Broad Institute of Harvard and MITCambridgeMAUSA Department of Life Sciences and Institute of Genome Sciences National Yang Ming Chiao Tung UniversityTaiwanChina Bioinformatics and Biostatistics The Francis Crick InstituteLondonUK Mechanisms of Transcription Laboratory The Francis Crick InstituteLondonUK Department of Cellular and Molecular Medicine Panum InstituteUniversity of CopenhagenCopenhagenDenmark

Familial dysautonomia(FD), a hereditary sensory and autonomic neuropathy, is caused by a mutation in the Elongator complex protein 1(ELP1) gene that leads to a tissue-specific reduction of ELP1 protein. Our work to generate a phenotypic mouse model for FD headed to the discovery that homozygous deletion of the mouse Elp1 gene leads to embryonic lethality prior to mid-gestation. Given that FD is caused by a reduction, not loss, of ELP1, we generated two new mouse models by introducing different copy numbers of the human FD ELP1 transgene into the Elp1 knockout mouse(Elp1) and observed that human ELP1 expression rescues embryonic development in a dose-dependent manner. We then conducted a comprehensive transcriptome analysis in mouse embryos to identify genes and pathways whose expression correlates with the amount of ELP1. We found that ELP1 is essential for the expression of genes responsible for nervous system development. Further, gene length analysis of the differentially expressed genes showed that the loss of Elp1 mainly impacts the expression of long genes and that by gradually restoring Elongator, their expression is progressively rescued. Finally, through evaluation of co-expression modules, we identified gene sets with unique expression patterns that depended on ELP1 expression.

关键词： ELP1 Elongator Transcriptional elongation Familial dysautonomia Neurodevelopmental disease

Analysis of a New Toothbrushing Technique through Plaque Removal Success

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Open Journal of Stomatology 2024年第3期14卷 133-152页

作者： Elhadi A. A. Shkorfu serkan Kurt Fatih Atalar Ali Olamat Aysel Ersoy Department of Electrical and Electronic Engineering Istanbul University-Cerrahpa&scedila Avc&imathlar Istanbul Türkiye Department of Electronics and Communication Engineering Y&imathld&imathz Technical University Istanbul Türkiye Department of Bioengineering Y&imathld&imathz Technical University Istanbul Türkiye

Background/Aims: Determining the levels of oral health and the quality of dental care are fundamental to building concepts of oral health. This study aims to assess toothbrushing techniques using a technical and physical model, clarifying how children and pre-adults learn to brush their teeth. Materials and Methods: Data were recorded from 23 participants, both male and female of various ages, using a proposed electronic toothbrush equipped with X-Y-Z axes pathways. The data, collected before and after training experiments, were processed with MATLAB to generate plots for the three axes. Results: The study revealed that most parameter values, such as Mean Difference Between Amplitudes (MAV, 6.00), Wilson Amplitude (WAMP, 179.419), and Average Amplitude Coupling (AAC, 1.270), decreased from before to after the experiments. Furthermore, the average overall epoch lengths (AVG) showed a 75% reduction in movement amplitude between the two experiments. Conclusion: Dentist observations indicated which brushing methods were acceptable or not. Analytical values suggest that individuals learn the toothbrushing technique effectively, and medical observations clearly demonstrate the success of the proposed method.

关键词： Techno-Physical Toothbrushing Oral Hygiene Education Dental Technology Plaque Analysis

Erratum to “Plant Defense against Necrotrophic Pathogens” [American Journal of Plant Sciences 11(12) (2020) 2122-2138]

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American Journal of Plant Sciences 2024年第2期15卷 122-138页

作者： Mahmoud H. Ghozlan Nikita Gambhir Eman EL-Argawy serkan Tokgöz Dilip K. Lakshman Amitava Mitra University of Nebraska Lincoln NE USA USDA-ARS Beltsville MD USA

The original online version of this article (Ghozlan, M.H., EL-Argawy, E., Tokgöz, S., Lakshman, D.K. and Mitra, A. (2020) Plant Defense against Necrotrophic Pathogens. American Journal of Plant Sciences, 11, 2122-2138. https://***/10.4236/ajps.2020.1112149) was published mistakenly without another co-author, Nikita Gambhir. In this regard, we revise authors and “how to cite” sections by adding her name.

关键词： Effectors Host Immunity Signaling P/MAMP ETI Disease Resistance

A Model for Cross-Domain Opinion Target Extraction in Sentiment Analysis

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Computer Systems Science & Engineering 2022年第9期42卷 1215-1239页

作者： Muhammet Yasin PAK serkan GUNAL Department of Computer Engineering Eskisehir Technical UniversityEskisehirTurkiye

Opinion target extraction is one of the core tasks in sentiment analysison text data. In recent years, dependency parser–based approaches have beencommonly studied for opinion target extraction. However, dependency parsersare limited by language and grammatical constraints. Therefore, in this work, asequential pattern-based rule mining model, which does not have such constraints,is proposed for cross-domain opinion target extraction from product reviews inunknown domains. Thus, knowing the domain of reviews while extracting opinion targets becomes no longer a requirement. The proposed model also revealsthe difference between the concepts of opinion target and aspect, which are commonly confused in the literature. The model consists of two stages. In the firststage, the aspects of reviews are extracted from the target domain using the rulesautomatically generated from source domains. The aspects are also transferredfrom the source domains to a target domain. Moreover, aspect pruning is appliedto further improve the performance of aspect extraction. In the second stage, theopinion target is extracted among the aspects extracted at the former stage usingthe rules automatically generated for opinion target extraction. The proposedmodel was evaluated on several benchmark datasets in different domains andcompared against the literature. The experimental results revealed that the opiniontargets of the reviews in unknown domains can be extracted with higher accuracythan those of the previous works.

关键词： Opinion target extraction aspect extraction sentiment analysis

Lacunary Generating Functions of Hybrid Type Polynomials in Viewpoint of Symbolic Approach

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Computer Modeling in Engineering & Sciences 2022年第2期130卷 903-921页

作者： Nusrat Raza Umme Zainab serkan Araci Mathematics Section Women’s CollegeAligarh Muslim UniversityAligarh202002India Department of Mathematics AligarhMuslim UniversityAligarh202002India Department of Economics Faculty of EconomicsAdministrative of Social SciencesHasan Kalyoncu UniversityGaziantepTR-27410Turkey

In this paper,we introduce mon-symbolic method to obtain the generating functions of the hybrid class of Hermite-associated Laguerre and its associated *** obtain the series definitions of these hybrid special ***,we derive the double lacunary generating functions of the Hermite-Laguerre polynomials and the Hermite-Laguerre-Wright ***,we find multiplicative and derivative operators for the Hermite-Laguerre-Wright polynomials which helps to find the symbolic differential equation of the Hermite-Laguerre-Wright *** concluding remarks are also given.

关键词： Hermite-laguerre polynomials laguerre-wright polynomials hermite-laguerre-wright polynomials hermite-mittag-leffler functions

Assessing fire severity in Turkey's forest ecosystems using spectral indices from satellite images

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林业研究:英文版 2023年第6期34卷 1747-1761页

作者： Coşkun Okan Güney Ahmet Mert serkan Gülsoy Department of Forest Fires Aegean Forestry Research Institute35430 IzmirTurkey Department of Wildlife Ecology and Management Faculty of ForestryIsparta University of Applied Science32260 IspartaTurkey Department of Soil Science and Ecology Faculty of ForestryIsparta University of Applied Science32260 IspartaTurkey

Fire severity classifications determine fire damage and regeneration potential in post-fire areas for effective implementation of restoration *** fire damage varies according to vegetation and fire characteristics,regional assessment of fire severity is *** objectives of this study were:(1)to test the performance of different satellite imagery and spectral indices,and two field—measured severity indices,CBI(Composite Burn Index)and GeoCBI(Geometrically structured Composite Burn Index)to assess fire severity;(2)to calculate classification thresholds for spectral indices that performed best in the study areas;and(3)to generate fire severity maps that could be used to determine the ecological impact of forest *** large fires in Pinus brutia(Turkish pine)and Pinus nigra *** ***(Anatolian black pine)—dominated forests during 2020 and 2021 were selected as study *** results show that GeoCBI provided more reliable estimates of field—measured fire severity than *** Sentinel-2 and Landsat-8/OLI images performed similarly well,MODIS performed *** severity classification thresholds were determined for Sentinel-2 based RdNBR,dNBR,dSAVI,dNDVI,and dNDMI and Landsat-8/OLI based dNBR,dNDVI,and *** several spectral indices,the highest accuracy for fire severity classification was found for Sentinel-2 based RdNBR(72.1%)and Landsat-8/OLI based dNBR(69.2%).The results can be used to assess and map fire severity in forest ecosystems similar to those in this study.

关键词： Remote sensing Forest fire Fire severity Spectral indices Composite burn index

Melatonin alleviates oxidative stress,inflammation,apoptosis,and DNA damage in acrylamide-induced nephrotoxicity in rats

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Asian Pacific Journal of Tropical Biomedicine 2023年第3期13卷 121-130页

作者： Fatmaİbaokurgil Hakan Aydin serkan Yildirim Emin Sengul Department of Physiology Faculty of Veterinary MedicineAtatürk UniversityErzurumTurkey Department of Virology Faculty of Veterinary MedicineAtatürk UniversityErzurumTurkey Department of Pathology Faculty of Veterinary MedicineAtatürk UniversityErzurumTurkey

Objective:To investigate the effects of melatonin on renal inflammation,oxidative stress,apoptosis,as well as DNA and tissue damage in acrylamide-induced nephrotoxicity in ***:Fifty male rats were randomly divided into five *** control group received distilled water by gastric lavage for 11days and the acrylamide group was administered acrylamide(50 mg/kg,i.g.)for 11 *** MEL10+ACR and MEL20+ACR groups received intraperitoneal melatonin 10 and 20 mg/kg,respectively,for 11 days,and acrylamide(50 mg/kg,i.g.)was administered 1h after melatonin *** MEL20 group was injected with melatonin(20 mg/kg)for 11 *** function tests were performed and biochemical and inflammatory parameters were *** addition,histopathological,immunohistochemical,and immunofluorescence examinations were carried ***:Melatonin significantly abated acrylamide-induced rise in serum urea and creatinine *** caused oxidative stress,inflammation,apoptosis,as well as DNA and tissue damage in the *** treatment alleviated acrylamide-induced renal damage by exhibiting antioxidant,anti-inflammatory,and antiapoptotic ***,melatonin significantly ameliorated acrylamide-caused histopathological changes in kidney ***:Melatonin attenuates acrylamide-induced renal oxidative stress,inflammation,apoptosis,and DNA damage in rats.

关键词： Acrylamide Apoptosis Inflammation Melatonin Nephrotoxicity Oxidative stress Rat

Manufacturing of high-performance light-weight mortar through addition of biochars of millet and maize

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Waste Disposal and Sustainable Energy 2023年第1期5卷 97-111页

作者： Seemab Tayyab Anwar Khitab Abdullah Iftikhar Raja Bilal Nasar Khan Mehmet serkan Kirgiz Department of Civil Engineering Mirpur University of Science and Technology(MUST)Mirpur10250AJ&KPakistan Department of Architecture Faculty of Engineering and Natural Sciencesİstanbul Sabahattin Zaim UniversityIstanbul34303Turkey

Agricultural wastes are environmental hazards,as these wastes can catch fire,resulting in the loss of human and animal lives and ***,the wastes are dumped in large spaces,which are already *** composites are quasi-brittle and develop cracks at the micro and nano level,which affect their strength,durability,and *** agricultural wastes to biochar and using it as fibers in cementitious materials for crack arresting and enhancing fracture toughness is an environment-friendly *** this research,nano to microscale carbonaceous inert fibers(biochar)of millet and maize were prepared through pyrolysis followed by ball *** X-ray spectroscopy(EDX)revealed that 82.08%and 86.89%of the carbon content was retained in millet and maize,*** scanning electron microscope(SEM)confirmed the presence of angular,flaky,and needle-like particles in the carbonaceous inerts,which may enhance the strength and the fracture response of the cementitious *** inerts were added individually to mortar specimens at dosage levels of 0,0.025%,0.05%,0.08%,0.2%and 1%by mass of *** dispersion of the synthesized nano inerts was ensured by UV–VIS *** compressive strength,flexural strength,porosity,and fracture toughness of cement mortar were *** carbonized nano intrusions reduced the porosity and density of the mortar *** minimum porosity was noted with 1%and 0.08%dosages of millet and maize,respectively,whereas the minimum density was observed at 1%dosage for *** increase in compressive and flexural strengths was also *** compressive strength increased by 32%and 28%with 0.2%and 0.5%millet and maize,*** increase of 168%and 114%in fracture toughness was noticed at optimized dosages of 0.5%and 1%of maize and millet,*** is concluded that the addition of carbonaceous inert fibers of millet and maize resulted in light-weight porous mortars with

关键词： Mortar Biochar Carbon sequestration Lightweight Strength Fracture toughness

Evaluation of rainwater harvesting and shrub establishment methods for sustainable watershed management in northern Afghanistan

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Journal of Mountain Science 2022年第8期19卷 2346-2359页

作者： LOUHAICHI Mounir HASSAN Sawsan GAMOUN Mouldi SAFI Navin ABDALLAH Mohamed A.B. ATES serkan International Center for Agricultural Research in the Dry Areas(ICARDA) Tunis 1004Tunisia Department of Animal and Rangeland Sciences Oregon State UniversityCorvallisOR 97331USA International Center for Agricultural Research in the Dry Areas(ICARDA) Amman 11185Jordan Consultant-Field Assistant Mazar Sharif 1703Afghanistan

Watershed rangelands in Northern Afghanistan provide various ecosystem services that support the local people's livelihoods,but they are now highly degraded essentially due to the continuous high grazing pressure and recurrent *** of shrub establishment method enhanced by water harvesting techniques to rehabilitate degraded rangelands have not been well *** main goal of this study was to evaluate the impact of direct seeding and transplanting of seedlings in combination with semi-circular bunds on growth,yield,and survival rate of four shrub species(Atriplex halimus,Atriplex nummularia,Atriplex lentiformis,andMaireana brevifolia)under semi-arid conditions of Sayyad village,Khulm *** rate(%),plant height,width,and plant length(cm)and plant cover(%)were measured for each plant over five occasions.A non-destructive reference unit was used to estimate biomass *** results showed that growth attributes and biomass production of shrubs were consistently greater in the transplanting compared to direct *** average,the plant length,width,height,volume,cover,and biomass production of transplanted shrubs were greater than direct-seeded shrubs by 24.3%,8.6%,8.7%,121.5%,13.8% and 34.1%,*** production of transplanted seedlings was the highest for ***(1313.5 g DM/plant)and ***(800 g DM/plant).There was a strong correlation between plant biomass production and plant volume(R^(2)_(Plant volume)=0.88)for the shrub ***,indicating that plant volume is a key variable for assessing biomass production for this ***,the survival rate of *** was 100% in both planting methods,suggesting that based on better survival this halophytic plant has great potential when restoring degraded ***,on the basis of better growth rates,yield,and survival,transplanting *** *** may enhance shrub establishment and contribute to the rehabilitation of slop

关键词： Biomass production Land degradation Rangeland rehabilitation Seed germination Shrub survival Vegetation cover Water harvesting