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Neural functions of small heat shock proteins

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Neural Regeneration Research 2022年第3期17卷 512-515页

作者： Teresa de los Reyes sergio Casas-Tintó Instituto Cajal CSICMadridSpain

Stress response is a cellular widespread mechanism encoded by a common protein program composed by multiple cellular factors that converge in a defense reaction to protect the cell against *** many mechanisms described,heat shock proteins were proposed as universally conserved protective factors in the stress core proteome,coping with different stress stimuli through its canonical role in protein ***,emerging evidences reveal non-canonical roles of heat shock proteins relevant for physiological and pathological ***,we review the implications of inducible heat shock proteins in the central nervous system *** particular,we discuss the relevance of heat shock proteins in the maintenance of synapses,as a balanced protective mechanism in central nervous system development,pathological conditions and aging.

关键词： aging central nervous system chaperones environment neuroprotection pathology stress synapses

Sliding Mode Control in Power Converters and Drives: A Review

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IEEE/CAA Journal of Automatica Sinica 2022年第3期9卷 392-406页

作者： Ligang Wu Jianxing Liu sergio Vazquez Sudip K.Mazumder IEEE Department of Control Science and Engineering Harbin Institute of TechnologyHarbin 150001China Electronic Engineering Department Universidad de Sevilla41092 SevillaSpain Electrical and Computer Engineering Department University of Illinois ChicagoChicagoIL 60607 USA

Sliding mode control(SMC)has been studied since the 1950s and widely used in practical applications due to its insensitivity to matched *** aim of this paper is to present a review of SMC describing the key developments and examining the new trends and challenges for its application to power electronic *** fundamental theory of SMC is briefly reviewed and the key technical problems associated with the implementation of SMC to power converters and drives,such chattering phenomenon and variable switching frequency,are discussed and *** recent developments in SMC systems,future challenges and perspectives of SMC for power converters are discussed.

关键词： Motor drive power electronics systems sliding mode control

Thermo-electro-mechanical microstructural interdependences in conductive thermoplastics

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npj Computational Materials 2023年第1期9卷 955-965页

作者： Javier Crespo-Miguel sergio Lucarini Angel Arias Daniel Garcia-gonzalez Department of Continuum Mechanics and Structural Analysis Universidad Carlos III de MadridAvda.de la Universidad 3028911 LeganésMadridSpain Department of Civil and Environmental Engineering Imperial College of LondonSouth Kensington CampusLondon SW72AZUK

Additive manufacturing has enabled the design of thermoplastic components that provide structural support,electrical conductivity and heat generation modulated by mechanical *** mechanisms and interplays that govern the material response at the microstructural level remain,however,***,we develop an experimental method to characterise conductive filaments from a combined mechanical,electrical and thermal *** approach is used to unravel exciting material interplays of conductive polylactic *** overcome experimental limitations that prevent a complete microstructural analysis of the problem,we develop a full-field homogenisation framework and implement it for finite *** framework accounts for viscoplasticity,electrical and thermal conduction,convection and heat generation via Joule effect,as well as for the interdependences between *** experimental validation,the framework is applied to virtually optimise fabrication requirements to obtain desired properties in final products,i.e.,stiffer products,filaments with higher conductivities or with better sensing capabilities.

关键词： conductive electrical overcome

Decoupled Photovoltaic Power Ramp-rate Calculation Method for Perturb and Observe Algorithms

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Journal of Modern Power Systems and Clean Energy 2022年第4期10卷 932-940页

作者： Jose Miguel Riquelme-Dominguez Francisco M.gonzalez-Longatt sergio Martinez Electrical Engineering Department Escuela Tecnica Superior de Ingenieros IndustrialesUniversidad Politecnica de Madrid28006 MadridSpain Department of Electrical Engineering Information Technology and CyberneticsUniversity of South-Eastern Norway3918 PorsgrunnNorway

As photovoltaic energy increasingly penetrates in power systems,transmission system operators have started to request its participation in providing ancillary *** of the demanded services is the power ramp-rate control(PRRC),which attempts to limit the power ramps produced by intermittent irradiance *** order to achieve the desired objective,solutions based on storage systems or modifying the maximum power point tracking(MPPT)in perturb and observe(P&O)algorithms are commonly *** starting point in PRRC is the determination of the instantaneous power ramprate,and different methods have been proposed in the literature for its ***,the accuracy and computational speed of existing procedures can be improved,which may be critical in situations with rapid irradiance *** this paper,a decoupled photovoltaic power ramp-rate calculation method is presented,in which the effect of variable irradiance and the P&O algorithm are computed *** proposed method has been theoretically demonstrated and tested through simulation and experimental *** results show that it can improve the previous methods in terms of accuracy and computation *** validation with hardware-inthe-loop demonstrates the suitability of the proposed method for real-time applications,even in presence of noisy measurements.

关键词： Hardware-in-the-loop maximum power point tracking perturb and observe photovoltaic power ramp-rate control ramp-rate calculation method

Electrochemical Corrosion Study in H₂SO₄ of NiAl with Cu Additions, Microstructure and Micro-Hardness at Room Temperature

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Journal of Minerals and Materials Characterization and Engineering 2022年第3期10卷 225-241页

作者： Jesús M. Colín de la Cruz sergio A. Serna Barquera Alvaro Torres-Islas Arturo Molina-Ocampo Edgar Valenzuela José G. gonzález Rodríguez Universidad Autónoma del Estado de Morelos Facultad de Ciencias Químicas e Ingeniería UAEM-FCQeI. Av. Universidad 1001Colonia Chamilpa Cuernavaca Morelos México Universidad Autónoma del Estado de Morelos Centro de Investigación en Ingeniería y Ciencias Aplicadas UAEM-CIICAp Cuernavaca Morelos México UABC Baja California Sur México

For many years, intermetallic materials promise applications in a wide variety of technology areas. NiAl intermetallic compound is material that exhibits important characteristics such as high corrosion resistance and low density besides its ability to retain strength and stiffness at elevated temperatures. However NiAl intermetallic is too hard, brittle and exhibits very low ductility at room temperature being the reason because this material is not yet available for structural applications. In order to increase the ductility of the NiAl intermetallic compound, the addition of a third alloying element has been proved, nevertheless it is important to determine if such additions decrease or increase the hardness and the corrosion resistance of the alloy. So, the present investigation reports the corrosion performance of the NiAl intermetallic compound modified with Cu, emphasizing the EIS analysis and the relation between physical parameters and the modelling equations used in the Equivalent Electric Circuit. It was found that the addition of Cu promotes the formation of the γ’-Ni3Al phase in Cu contents greater than 15 at. %, in addition to a decrease in micro hardness and an increment in the Icorr values. In this way, the electrochemical characterization evidenced a high corrosion resistance of these intermetallic alloys.

关键词： NiAl-Cu Corrosion Behavior Electrochemical Impedance Spectrum Vickers Micro Hardness Microstructure

Architecture as device:Estrangement theory from literature to architecture

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Frontiers of Architectural Research 2022年第1期11卷 1-12页

作者： Qirui Wan sergio Martín Blas Department of Architectural Design ETSAMUniversidad Politécnica de MadridMadrid28040Spain

What is the estrangement of architecture?The concept has been incessantly mentioned by academics while there seems to be a lack of discussion systematically sorting out the significance,influence,and origins of estrangement asanarchitectural *** aims to discern the meaning of estrangement from the beginning and its process of entering the field of *** first part is expected to answer the following questions:what is estrangement’s original meaning in the field of literature and its variantions?The second part determines what estrangement is in architecture and in what form estrangement is represented according to these *** third part points out the difference during this translation fromliterature to architecture and demonstrates the reasonable inference thatmay actually compose the possibleway of applying the estranging technique in architecture.

关键词： Estrangement Architectural strategy Literature concept Decontextualization Anthropopathic architecture

Performance evaluation of lateral canopy shakers with catch frame for continuous harvesting of oranges for juice industry

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International Journal of Agricultural and Biological Engineering 2020年第3期13卷 88-93,F0002页

作者： Rafael R.Sola-Guirado sergio Castro-Garcia Gregorio L.Blanco-Roldán Jesús A.Gil-Ribes Emilio J.gonzález-Sánchez Universidad de Córdoba Departamento de Ingeniería RuralE.T.S.I.Agronómica y de MontesCampus de RabanalesCtra.Nacional IV Km 396CordobaSpain

Citrus is mainly oriented to fresh consumption,and harvesting is usually performed ***,the high cost of harvesting and the low availability of labour can compromise the profitability of the crop when it is destined to juice *** development of citrus mechanical harvesting for industrial processing is conditioned to reach a high fruit removal efficiency,with a reduced damage to both fruit and *** current machines available are very large,requiring extensive plantations with long rows of trees to be *** this study,two lateral canopy shakers equipped with a catch frame were evaluated to harvest independently both sides of the hedge on intensive citrus plantations with the main objective of determining their performance and *** lateral canopy shakers tested were three tractor-drawn machines,one commercial machine and two *** tested machines reached a mean value of 78%of fruit ***,the prototypes,equipped with a catch frame,were able to recover a mean value of 70%of *** the results were promising,for achieving an efficient result,the application of this harvesting technology still requires a process of improvement,and the adaptation of both the machine and the *** machines should reduce the amount of post-harvest ground fruit(5.9%-10.4%).Tree damages generated by the contact of the catch frame with the trunk and the metal rods with main branches were the most ***,it is still necessary to increase the ground speed of the machinery and improving the design of the rods,regulating the rod penetrating deep in the canopy to improve the fruit recovery and limit the damage caused to the trees.

关键词： harvester mechanical harvesting fruit removal tree damage Citrus sinensis L.Osbeck

Experimental model standardizing polyvinyl alcohol hydrogel to simulate endoscopic ultrasound and endoscopic ultrasoundelastography

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World Journal of Gastroenterology 2020年第34期26卷 5169-5180页

作者： Elymir S Galvis-García sergio Sobrino-Cossío Arturo Reding-Bernal Yesica Contreras-Marín Karina Solórzano-Acevedo Patricia gonzález-Zavala Rosa M Quispe-Siccha Unidad de Endoscopía Gastrointestinal Hospital General de México"Dr.Eduardo Liceaga"Mexico 06720Mexico Unidad de Endoscopia y Fisiología Digestiva HospitalÁngeles del PedregalMexico 10700Mexico Dirección de Investigación Hospital General de México“Dr.Eduardo Liceaga”Mexico 06720Mexico Unidad Profesional Interdisciplinaria de Biotecnología and Unidad de Investigación y Desarrollo Tecnológico Instituto Politécnico Nacional and Hospital General de México"Dr.Eduardo Liceaga"Mexico 06720Mexico Instituto de Investigaciones en Materiales and Unidad de Investigación y Desarrollo Tecnológico Universidad Nacional Autónoma de México and Hospital General de México"Dr.Eduardo Liceaga"Mexico 06720Mexico Unidad de Investigación y Desarrollo Tecnológico Hospital General de México"Dr.Eduardo Liceaga"Mexico 06720Mexico

BACKGROUND Endoscopic ultrasound(EUS)and endoscopic ultrasound elastography(EUS-E)simulation lessens the learning curve;however,models lack realism,diminishing *** To standardize the mechanical properties of polyvinyl alcohol(PVA)hydrogel for simulating organs and digestive *** PVA hydrogel(Sigma Aldrich,degree of hydrolysis 99%)for simulating EUS/EUS-E lesions was investigated in Unidad de Investigación y Desarrollo Tecnológico at Hospital General de México“*** Liceaga”,Mexico *** evaluated physical,contrast,elasticity and deformation coefficient characteristics in lesions,applying Kappa’s concordance and satisfaction questionnaire(Likert 4-points).RESULTS PVA hydrogel showed stable mechanical *** depended on molecular weight(MW)and concentration(C).PVA bblocks with the greatest density showed lowest tensile strength(r=-0.8,P=0.01).Lesions were EUSgraphically *** and heterogeneous examples were created from PVA blocks or PVA phantoms,exceeding(MW2=146000-186000,C9=15%and C10=20%)with a density under(MW1=85000-124000,C1=7%and C2=9%).We calculated elasticity and deformation parameters of solid(blue)areas,contrasting with the norm(Kappa=0.8;high degree of satisfaction).CONCLUSION PVA hydrogels were appropriate for simulating organs and digestive lesions using EUS/EUS-E,facilitating practice and reducing *** amplified skills,while reducing the learning curve.

关键词： Endoscopic ultrasound simulators in endoscopy Polyvinyl alcohol Endoscopic ultrasound Endoscopic ultrasound elastography Strain Elasticity

Origin and evolution of the genera Lonsdaleia and Actinocyathus:Insights for the Mississippian palaeogeography from the western Palaeotethys

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Journal of Palaeogeography 2023年第2期12卷 296-310页

作者： Isabel Rodríguez-Castro Ian D.Somerville sergio Rodríguez Departamento de Geodinamica Estratigrafía y PaleontologíaUniversidad Complutense de Madrid28040MadridSpain UCD School of Earth Sciences University College DublinBelfieldDublin 4Ireland Instituto de Geociencias(CSIC UCM)Ciudad Universitaria28040MadridSpain

Representatives of the subfamily Lonsdaleiinae Chapman,1893 are common in the Mississippian of the western Palaeotethys.A general analysis of the origin,distribution and evolution of that subfamily has been *** most probable hypothesis for the origin of the genus Lonsdaleia McCoy,1849 is to acquire colonialism via the genus Axophyllum Milne Edwards and Haime,*** d'Orbigny,1849 would be a descendant of Lonsdaleia by increasing integration in the *** first occurrences of Lonsdaleia have been recorded in the lower Visean from northern Britain and northern Tianshan Mountains of northwestern China,but the diversification and migration to the whole Palaeotethys only happened in the late *** hypotheses are proposed on that *** Serpukhovian was also a period of migrations and diversification for these *** Lonsdaleia and Actinocyathus have been recorded in Bashkirian refuges,the Sverdrup Basin in northern Laurasia and the Tindouf Basin in northern Africa,*** division of the western Palaeotethys into six subprovinces based on the distribution of corals is proposed.

关键词： Carboniferous Palaeotethys Biogeography Evolution Rugosa