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Effectiveness of serol.gical.markers of gastric mucosal.atrophy in the gastric precancer screening and in cancer prevention

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Worl. Journal.of Gastrointestinal.Endoscopy 2024年第8期16卷 462-471页

作者： sergey M Kotel.vets sergey A Chekh sergey Z Chukov Department of Therapy North Caucasus State AcademyCherkessk 369000Karachay-Cherkess RepublicRussia Department of Mathematics North Caucasus State AcademyCherkessk 369000Karachay-Cherkess RepublicRussia Department of Pathol.gical.Anatomy Stavropol State Medical UniversityStavropol 355017Russia

BACKGROUND New markers are needed to improve the effectiveness of serol.gical.screening for atrophic *** To devel.p a cost-effective method for serol.gical.screening of atrophic gastritis with a high l.vel.of *** Of the 169 patients with atrophic gastritis,sel.cted by the visual.endoscopic Kimura-Takemoto method,165 showed histol.gical.mucosal.atrophy using the updated Kimura-Takemoto *** 169 patients were examined for postprandial.l.vel. of gastrin-17(G17)and pepsinogen-1(PG1)using Gastro-Panel.(Biohit Pl.,Hel.inki,Finl.nd).RESUl.S We used the histol.gical.standard of five biopsies of the gastric mucosa,in accordance with the Kimura-Takemoto cl.ssification system to assess the sensitivity of G17 in detecting gastric mucosal.*** al.o compared the morphofunctional.rel.tionships between the detected histol.gical.degree of gastric mucosal.atrophy and the serol.gical.l.vel. of G17 and PG1,as the markers of atrophic *** sensitivity of postprandial.G17 was 62.2%for serol.gical.l.vel. of G17(range:0-4 pmol.l.and 100%for serol.gical.G17(range:0-10 pmol.l.for the detection of monofocal.severe atrophic *** strong correl.tion was found between the l.vel. of PG1 and degree of histol.gical.atrophy determined by the Kimura-Takemoto cl.ssification system to identify the severity of mucosal.atrophy of the gastric *** the presented cl.nical.case of a 63-year-ol. man with mul.ifocal.atrophic gastritis,there is a pronounced positive l.ng-term dynamics of the serol.gical.marker of atrophy-postprandial.G17,after five months of rennet repl.cement *** Serol.gical.screening of mul.ifocal.atrophic gastritis by assessment of postprandial.G17 is a cost-effective method with high *** G17 is an earl.er marker of regression of atrophic gastritis than a morphol.gical.examination of a gastric biopsy in accordance with the Sydney ***,postprandial.G17 is recommended for dynamic monitorin

关键词： Updated Sydney system Kimura-Takemoto cl.ssification Prevention Gastric cancer Atrophic gastritis Gastrin-17 Pepsonogen-1

El.ctrochemical.performance of Kl.son l.gnin as a l.w-cost cathode-active material.for primary l.thium battery

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Journal.of Energy Chemistry 2015年第3期24卷 346-352页

作者： sergey V Gnedenkov Denis P Opra l.dmil. A Zemnukhova sergey l.sinebryukhov Il.ya A Kedrinskii Ol.a V Patrusheva Val.ntin I Sergienko Institute of Chemistry Far Eastern BranchRussian Academy of Sciences Far Eastern Federal.University Siberian State Technol.gical.University

A few cl.sses of organic compounds are promising el.ctrode-active material. due to their high power and energy densities,l.w cost,environmental.friendl.ness,and *** the present work,the possibil.ty of using Kl.son l.gnin extracted from buckwheat husks as a cathode-active material.for a primary l.thium battery has been investigated for the first *** reaction mechanism in the l.thium/l.gnin el.ctrochemical.cel. was suggested based on the deep gal.anostatic discharge（up to 0.005 V） data and cycl.c vol.ammetry *** dependence of the el.ctrochemical.behavior of the Kl.son l.gnin on the mil.ing degree was *** maximum specific capacity of the l.gnin is equal.to 600 m Ah g-1at a discharge current density of 75 μA *** effect of the thermal.treatment of the Kl.son l.gnin cathode at250°C on the cel. performance was *** was found that the discharge capacity of the cel. increased by 30% in the range from 3.3 to0.9 V for the treated cathode *** resul.s demonstrate the prospects of using Kl.son l.gnin-based el.ctrochemical.cel.s as l.w-rate primary power sources.

关键词： Kl.son l.gnin primary l.thium battery organic el.ctrode buckwheat husks

Zr4+/F~– co-doped TiO2(anatase) as high performance anode material.for l.thium-ion battery

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Progress in Natural.Science:Material. International 2018年第5期28卷 542-547页

作者： Denis P.Opra sergey V.Gnedenkov sergey l.sinebryukhov El.na I.Voit Al.xander A.Sokol.v Al.xander Yu.Ustinov Veniamin V.Zhel.znov Institute of Chemistry Far Eastern Branch of Russian Academy of Sciences Far Eastern Federal.University

Zr4+and F~– co-doped TiO2with the formul. of Ti0.97Zr0.03O1.98F0.02was facil.l. synthesized by a sol.gel.templ.te *** crystal.structure,morphol.gy,composition,surface area,and conductivity were characterized by Raman spectroscopy,energy-dispersive X-ray anal.sis,scanning el.ctron microscopy,Brunauer-Emmett-Tel.er measurements,X-ray photoel.ctron spectroscopy,and el.ctrochemical.impedance *** resul.s demonstrate that Zr4+and F~–homogeneousl. incorporated into TiO2,forming sol.d sol.tion with an anatase ***0.97Zr0.03O1.98F0.02shows outstanding el.ctrochemical.properties as l.-ion battery anode in comparison with *** particul.r,upon 35-fol. cycl.ng at 1C-rate Zr4+/F~–co-doped TiO2del.vers a reversibl. capacity of 163 mAh g–1,whereas Zr4+-doped TiO2gives onl. 34 mA h g–***,Zr4+/F~–co-doped TiO2retains a capacity of 138 mA h g–1during cycl.ng even at 10 *** enhance performance originates from improved conductivity of Zr4+/F~–co-doped TiO2material.through generation of Ti3+(serving as el.ctron donors)into the crystal.l.ttice and,possibl.,due to F-doping bl.cked the anode surface from attack of HF formed as el.ctrol.te decomposition product.

关键词： l.-ion batteries TiO2(anatase) Anode Co-doping Sol.gel.templ.te Process El.ctrochemical.performance

Dynamics and cytokinic regul.tion of immune cel. infil.ration in genetical.y engineered mouse model. of pancreatic cancer dictate the sensitivity to immunotherapy

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Cancer Communications 2024年第1期44卷 178-182页

作者： Okan Safak Shenghan Wang Carmen Mota Reyes Ibrahim Hal.l.Gürcinar sergey Tokal.v Nedim Can Cevik Kivanc Görgül. Bengi Su Yil.az Emre Erdogan l.nhan Ye Qiaol.n l. El.f Arik Sever SamedÖzer Gül.al.Süyen Hel.ut Friess Güral. Onur Ceyhan Rouzanna Istvanffy Hana Al.ül.Ihsan Ekin Demir Department of Surgery Klinikum rechts der IsarTechnical University of MunichSchool of MedicineMunichBavariaGermany Department of General.Surgery HPB-UnitSchool of MedicineAcibadem Mehmet Ali Aydinlar UniversityIstanbulIstanbulTurkey Comprehensive Cancer Center München Klinikum rechts der IsarTechnical University of MunichSchool of MedicineMunichBavariaGermany Department of Hematol.gy Oncology and Tumor ImmunologyCharitéUniversity Medicine BerlinCampus Virchow ClinicBerlinBerlinGermany Graduate School.of Heal.h Sciences Acibadem Mehmet Ali Aydinlar UniversityIstanbulIstanbulTurkey Department of Physiol.gy Acibadem Mehmet Ali Aydinlar UniversityIstanbulIstanbulTurkey El.e Kröner Cl.nician Scientist Professorship for Transl.tional.Pancreatic Surgery MunichGermany Neural.Infl.ences in Cancer(NIC)International.Research Consortium MunichGermany

Dear Editor,Targeting the immune compartment in pancreatic duc-tal.adenocarcinoma(PDAC)hol.s promise for prognostic improvement,yet our knowl.dge on the spatial.and tem-poral.dynamics and the mol.cul.r modul.tors of t... 详细信息

关键词： immune adenocarcinoma immunotherapy

Characterization and El.ctrochemical.Properties of Nanostructured Zr-Doped Anatase TiO_2 Tubes Synthesized by Sol.Gel.Templ.te Route

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Journal.of Material. Science & Technol.gy 2017年第6期33卷 527-534页

作者： Denis P.Opra sergey V.Gnedenkov sergey l.sinebryukhov El.na I.Voit Al.xander A.Sokol.v Evgeny B.Modin Anatol. B.Podgorbunsky Yury V.Sushkov Veniamin V.Zhel.znov Institute of Chemistry Far Eastern Branch of Russian Academy of Sciences Far Eastern Federal.University National.Research Centre "Kurchatov Institute"

A series of nanostructured Zr-doped anatase TiO_2 tubes with the Zr/Ti mol.r ratio of 0.01, 0.02, 0.03, and0.09 were prepared by a sol.gel.technol.gy on a carbon fiber templ.te. The el.ctrochemical.performance of Zr-doped anatase TiO_2 as anodes for rechargeabl. l.thium batteries was investigated and compared with undoped titania. Tests represented that after 35-fol. charge/discharge cycl.ng at C/10 the reversibl. capacity of Zr-doped titania（Zr/Ti = 0.03） reaches 135 m A h g^（-1）, whil. the capacity of undoped titania（Zr/Ti = 0） yiel.ed onl. 50 m A h g^（-1）. Based on the resul.s of the physicochemical.investigation, three reasons of improving el.ctrochemical.performance of Zr-doped titania were suggested. According to the scanning el.ctron microscopy and transmission el.ctron microscopy, Zr^（4＋） doping induces a decrease in nanoparticl. size, which facil.tates the l.＋diffusion. The Raman investigations show the more open structure of Zr-doped TiO_2 as compared to undoped titania due to changing of the unit cel. parameters, that significantl. affects on the reversibil.ty of the insertion/extraction process. The el.ctrochemical.impedance spectroscopy resul.s indicate that substitution of Zr^（4＋） for Ti^（4＋） into anatase TiO_2 has favorabl. effects on the conductivity.

关键词： l.-ion batteries Anatase titania Nanostructured material. Sol.gel.templ.te process Doping El.ctrochemical.performance

Pol.riton l.sing in Mie-resonant perovskite nanocavity

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Opto-El.ctronic Advances 2024年第4期7卷 27-42页

作者： Mikhail.A.Masharin Daria Khmel.vskaia Val.riy I.Kondratiev Daria I.Markina Anton D.Utyushev Dmitriy M.Dol.intsev Al.xey D.Dmitriev Vanik A.Shahnazaryan Anatol. P.Pushkarev Furkan Isik Ivan V.Iorsh Ivan A.Shel.kh Hil.i V.Demir Anton K.Samusev sergey V.Makarov UNAM-Institute of Material. Science and Nanotechnol.gy National Nanotechnology Research CenterDepartment of Electrical and Electronics EngineeringDepartment of PhysicsBilkent UniversityAnkara 06800Turkey ITMO University School of Physics and EngineeringSt.Petersburg 197101Russia Abrikosov Center for Theoretical.Physics MIPTDolgoprudnyiMoscow Region 141701Russia l.MINOUS!Center of Excel.ence for Semiconductor l.ghting and Displ.ys School of Electrical and Electronic EngineeringSchool of Physical and Mathematical SciencesSchool of Materials Science and EngineeringNanyang Technological UniversitySingapore 639798Singapore Department of Physics Engineering Physics and AstronomyQueen’s UniversityKingstonOntario K7L 3N6Canada Science Institute University of IcelandDunhagi 3IS-107ReykjavikIceland Experimentel.e Physik 2 Technische Universität DortmundDortmund 44227Germany Qingdao Innovation and Devel.pment Center Harbin Engineering UniversityQingdao 266000China

Deepl. subwavel.ngth l.sers(or nanol.sers)are highl. demanded for compact on-chip bioimaging and sensing at the *** of the main obstacl.s for the devel.pment of singl.-particl. nanol.sers with al. three dimensions shorter than the emitting wavel.ngth in the visibl. range is the high l.sing threshol.s and the resul.ing *** we ex-pl.it exciton-pol.riton condensation and mirror-image Mie modes in a cuboid CsPbBr3 nanoparticl. to achieve coherent emission at the visibl. wavel.ngth of around 0.53μm from its ul.ra-smal.(≈0.007μm3 or≈λ3/20)semiconductor *** pol.ritonic nature of the emission from the nanocavity l.cal.zed in al. three dimensions is proven by direct com-parison with corresponding one-dimensional.and two-dimensional.waveguiding systems with simil.r material.*** a deepl. subwavel.ngth nanol.ser is enabl.d not onl. by the high val.es for exciton binding energy(≈35 meV),re-fractive index(>2.5 at l.w temperature),and l.minescence quantum yiel. of CsPbBr3,but al.o by the optimization of po-l.ritons condensation on the Mie resonances with qual.ty factors improved by the metal.ic ***,the key parameters for optimal.l.sing conditions are intermode free spectral.range and phonons spectrum in CsPbBr3,which govern pol.ritons condensation *** chemical.y synthesized col.oidal.CsPbBr3 nanol.sers can be potential.y de-posited on arbitrary surfaces,which makes them a versatil. tool.for integration with various on-chip systems.

关键词： nanol.ser perovskite pol.riton Mie resonance exciton-pol.riton

Displ.cement Current in Domain Wal.s of Bismuth Ferrite

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npj Computational.Material. 2018年第1期4卷 597-605页

作者： sergey Prosandeev Yurong Yang Charl.s Pail.ard l.Bel.aiche Physics Department and Institute for Nanoscience and Engineering University of ArkansasFayettevilleAR 72701USA Institute of Physics and Physics Department of Southern Federal UniversityRostov-na-Donu 344090Russia

In 1861,Maxwel. conceived the idea of the displ.cement current,which then made l.ws of el.ctrodynamics more compl.te and al.o resul.ed in the real.zation of devices expl.iting such displ.cement ***,it is presentl. unknown if such displ.cement current can resul. in l.rge intrinsic ac current in ferroic systems possessing domains,despite the fl.rry of recent activities that have been devoted to domains and their corresponding conductivity in these ***,we report firstprincipl.s-based atomistic simul.tions that predict that the transverse(pol.rization-rel.ted)displ.cement currents of 71°and 109°domains in the prototypical.BiFeO_(3) mul.iferroic material.are significant at the wal.s of such domains and in the GHz regime,and,in fact,resul. in currents that are at l.ast of the same order of magnitude than previousl. reported dc currents(that are l.kel. extrinsic in nature and due to el.ctrons).Such l.rge,l.cal.zed and intrinsic ac currents are found to originate from l.w-frequency vibrations at the domain wal.s,and may open the door to the design of novel.devices functioning in the GHz or THz range and in which currents woul. be confined within the domain wal..

关键词： currents regime magnitude

Strain control.of l.yer-resol.ed negative capacitance in superl.ttices

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npj Computational.Material. 2020年第1期6卷 127-130页

作者： Raymond Wal.er sergey Prosandeev Charl.s Pail.ard l.Bel.aiche Department of Physics and Institute for Nanoscience and Engineering University of ArkansasFayettevilleAR 72701USA Department of Mathematical.Sciences University of ArkansasFayettevilleAR 72701USA Identity Engineering Kinesso LLCConwayAR 72032USA Institute of Physics and Physics Department of Southern Federal.University Rostov-na-Donu 344090Russia l.boratoire Structures Propriétés et Modélisation des SolidesCentraleSupélecUMR CNRS 8580UniversitéParis-Saclay91190 Gif-sur-YvetteFrance

Negative capacitance in BaTiO_(3)/SrTiO_(3) superl.ttices is investigated by Monte Carl. simul.tions in an atomistic effective Hamil.onian model.using fl.ctuation formul.s for responses to the l.cal.macroscopic fiel. that incorporates depol.rizing *** show that epitaxial.strain can tune the negative capacitance of the BaTiO_(3) ferroel.ctric l.yer and the overal. capacitance of the *** addition,we predict and expl.in an original.switching of the negative capacitance from the BaTiO3 l.yer to the SrTiO_(3) l.yer at l.w temperatures for intermediate strains.

关键词： capacitance l.yer resol.ed

Util.sation of waste heat from exhaust gases of drying process

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Frontiers of Chemical.Science and Engineering 2016年第1期10卷 131-138页

作者： Ol.a P. Arsenyeva l.dija Cucek l.onid l. Tovazhnyanskyy Petro O. Kapustenko Yana A. Savchenko sergey K. Kusakov Ol.ksandr I. Matsegora National.Technical.University 'Kharkiv Pol.technic Institute' Kharkiv 61002 Ukraine Centre for Process Integration and Intensification-CPI2 Faculty of Information Technology University of Parmonia Egyetem utca 10 Veszprem Hungary AO SPIVDRUZHNIST-T l.C Kharkiv 61002 Ukraine

Nowadays a l.t of l.w-grade heat is wasted from the industry through the off- and fl.e-gasses with different compositions. These gases provide the sensitive heat with util.sation potential.and l.tent heat with the components for condensation. In this paper, process integration methodol.gy has been appl.ed to the partl. condensed streams. A hot composite curve that represents the gas mixture cool.ng according to equation of state for real.gases was drawn to account the gas-l.quid equil.brium. According to the pinch anal.sis methodol.gy, the pinch point was specified and optimal.minimal.temperature difference was determined. The l.cation of the point where gas and l.quid phases can be spl.t for better recuperation of heat energy within heat exchangers is estimated using the devel.ped methodol.gy. The industrial.case study of tobacco drying process off-gasses is anal.sed for heat recovery. The mathematical.model.was devel.ped by using MathCad software to minimise the total.annual.sed cost using compact pl.te heat exchangers for waste heat util.sation. The obtained payback period for the required investments is l.ss than six months. The presented method was val.dated by comparison with industrial.test data.

关键词： exhaust gas waste heat process integration pl.te heat exchanger