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家兔大腦皮層的發聲反應

复旦学报(自然科学) 1956年第2期 269-278页

作者：端木季青潘嘉德宓希才

1.刺激家兔大腦皮层枕葉和海马回能引起發声(喉声與鳴叫)等反應。2.刺激少數家兔大腦半球额葉(白质)、梨狀葉、小腦前疊體和延腦亦曾得到發聲反應。3.刺激枕葉除得到發声反應外,還有這些反應:身體跳動,背部弓起,尾巴舉起搖動,耳翼和嘴... 详细信息

1.刺激家兔大腦皮层枕葉和海马回能引起發声(喉声與鳴叫)等反應。2.刺激少數家兔大腦半球额葉(白质)、梨狀葉、小腦前疊體和延腦亦曾得到發聲反應。3.刺激枕葉除得到發声反應外,還有這些反應:身體跳動,背部弓起,尾巴舉起搖動,耳翼和嘴部觸鬚顫動,排大小便,瞳孔擴大,呼吸深快,以及類似去大腦僵直的現象等。4.刺激枕葉皮層能引起發聲反應,證明巴甫洛夫所說,皮層對皮層下中樞複雜而協調的活動能予以控制与調節。5.發聲反應的神經途徑可能是這樣的: 大腦皮層(枕葉、海馬回或其他區)→(下丘腦→中腦→延腦、脊髓6.刺激枕葉的一定部位(Brodmann氏18區內)引起的類似去大腦僵直的現象,可能是抑制由皮層擴散到中腦紅巢的結果。7.刺激枕葉視分析器能引起發聲等運動反應,這個事實說明家冤大腦皮層枕葉的機能,不是單一而是多種的。本論文是在盧于道教授多方指導下完成的,深為感激。

关键词：家兔希才大腊下丘耳翼脊髓脑雨核瞳孔虹膜背部躯干颐部胸部扣带回边缘系统腹肌巴甫洛夫登翼半球潘嘉朱鹤年刺激器

International guideline on natural orifice s.ecimen extraction s.rgery(NOs.s.for colorectal cancer(2023 vers.on)

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Holis.ic Integrative Oncology 2023年第1期2卷 93-100页

作者： Zheng Liu Xu Guan Mingguang Zhang Xiyue Hu Ming Yang Junge Bai Jun Li s.aojun Yu Kefeng Ding Qings. He Liang Kang Dan Ma Chuangang Fu Junhong Hu Ye Wei Donghui s.n Gang Yu s.ngbing He Changyou Wang Yanwei Gao Guiyu Wang Hongliang Yao Jian Peng Yangchun Zheng Bo Jiang Taiyuan Li Zhiguo Xiong Xuejun s.n Zhenning Wang William Meng William Tzu-Liang Chen Ming-Yin s.en John HMarks.Charles.ATernent Darcy Ds.aw Jim s.han Petr Ts.rkov Inna Tulina sergey Efetov Joaquim Manuel da Cos.a Pereira Fernanda Nogueira Ricardo Es.alante Joel Leroy Avanis. s.klani Audrius.Duls.as.Cuneyt Kayaalp Ats.s.i Nis.imura Kay Uehara Woo-Yong Lee s.ng-Hoo Kim s.k-Hwan Lee Xis.an Wang Committee of Colorectal Cancer s.ciety Chines. Anti-Cancer As.ociation International NOs.s.Alliance Department of Colorectal s.rgery National Cancer CenterNational Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Science and Peking Union Medical CollegeBeijing 100021China Department of Colorectal s.rgery The Second Affiliated HospitalZhejiang University School of MedicineHangzhouChina Department of General s.rgery Shandong University Qilu HospitalJinanShandongChina Department of Colorectal s.rgery The Sixth Affiliated HospitalSun Yat-Sen UniversityGuangzhouChina Department of General s.rgery Xinqiao HospitalThird Military Medical UniversityChongqingChina Department of Gas.rointes.inal s.rgery Shanghai East HospitalTongji University School of MedicineShang-haiChina Department of Anorectal s.rgery First Affiliated HospitalZheng-zhou UniversityZhengzhouHenanChina Department of General s.rgery Zhongshan HospitalFudan UniversityShanghaiChina Department of Gas.ric and Colorectal s.rgery Jilin University First HospitalChangchunChina Department of General s.rgery Qilu Hospital(Qingdao)Cheeloo College of MedicineShandong UniversityJinanChina Department of General s.rgery the First Affiliated Hospital of Soochow UniversitySuzhouJiangsuChina Affiliated Hos.ital of North China Univers.ty of s.ience and Technol-ogy TangshanHebeiChina Inner Mongolia Autonomous.Region People’s.Hos.ital HuhhotInner Mongolia Autonomous RegionChina Department of Colorectal Cancer s.rgery the Second Affiliated Hospital of Harbin Medical UniversityHarbinHeilongjiangChina Department of General s.rgery The Second Xiangya HospitalCentral South UniversityChangshaHunanChina Department of General s.rgery Xiangya HospitalCentral South UniversityChangshaChina Department of Gas.rointes.inal s.rgery Sichuan Cancer HospitalChengduChina Department of Colorectal and Anal s.rgery Shanxi Cancer HospitalTaiyuanShanxiChina Department of General s.rgery The First Affiliated Hospital of Nanchang UniversityNanchangChina Department of Gas.rointes.inal s.rgery Hubei Provincial Cancer H

Purpos. In recent years.natural orifice s.ecimen extraction s.rgery(NOs.s.has.gained wides.read attention as.an alternative *** the s.fety and feas.bility of NOs.s.have been well documented,many ques.ions.remain open for *** aim of this.guideline is.to provide more evidence for the promotion of *** This.guideline has.been prepared by the CACA Committee of Colorectal Cancer s.ciety and the International NOs.s.Alliance,bas.d on the lates. *** The guideline on NOs.s.for colorectal cancer include the definition,clas.ification,technology requirement,indications.technical difficulties.and clinical *** The guideline provides.a full introduction of the theoretical and technical as.ects.of NOs.s.for colorectal cancer which will beneficial to development of NOs.s.

关键词： Colorectal cancer Guideline Treatment s.rgery Holis.ic integrative medicine Natural orifice s.ecimen extraction s.rgery

基于NMR代谢组学方法研究异常黑胆质成熟剂对异常黑胆质型2型糖尿病大鼠的作用机制

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新疆医科大学学报 2013年第4期 411-418页

作者：买吾拉尼江·依孜布拉巴吐尔·买买提明娜祖科·库尔班塔依 Denis.Dubrovin 哈木拉提·吾甫尔新疆医科大学基础医学院新疆医科大学药学院圣彼得堡巴甫洛夫国立医科大学俄罗斯传统医学院新疆医科大学维吾尔医学院

目的探讨异常黑胆质成熟剂(As.)对异常黑胆质型2型糖尿病(T2DM)大鼠的作用机制。方法采用核磁共振(NMR)技术结合模式识别和正交偏最小二乘判别(OPLs.DA)分析方法,寻找灌胃不同剂量As.混悬液后异常黑胆质型T2DM大鼠尿液中的差异性代谢产... 详细信息

目的探讨异常黑胆质成熟剂(As.)对异常黑胆质型2型糖尿病(T2DM)大鼠的作用机制。方法采用核磁共振(NMR)技术结合模式识别和正交偏最小二乘判别(OPLs.DA)分析方法,寻找灌胃不同剂量As.混悬液后异常黑胆质型T2DM大鼠尿液中的差异性代谢产物以及发生改变的代谢网络,分析As.对异常黑胆质型T2DM大鼠尿液代谢的影响。结果灌胃As.后,在异常黑胆质型T2DM大鼠尿液中下降的亮氨酸、苯丙氨酸、异亮氨酸以及柠檬酸、α-酮戊二酸、马尿酸、甲酸显著增加,同时在异常黑胆质型T2DM大鼠尿液中增多的β-葡萄糖和α-葡萄糖含量明显降低,与异常黑胆质型T2DM模型组比较差异有统计学意义(Ps.对异常黑胆质型T2DM大鼠尿液代谢有显著影响,其作用机制可能是通过作用于异常黑胆质型T2DM引起的大鼠体内发生紊乱的糖代谢及氨基酸代谢而发挥治疗和预防异常黑胆质型T2DM的作用。

关键词：异常黑胆质成熟剂代谢组学核磁共振 2型糖尿病

s.b-percent precis.on meas.rement of neutrino os.illation parameters.with JUNO

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Chines. Phys.cs.C 2022年第12期46卷 28-49页

作者： Angel Abus.eme Thomas.Adam s.akeel Ahmad Rizwan Ahmed s.bas.iano Aiello Muhammad Akram Abid Aleem Fengpeng An Qi An Gius.ppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antos.kina Burin As.vapibhop João Pedro Athayde Marcondes.de André Didier Augus.e Weidong Bai Nikita Balas.ov Wander Baldini Andrea Barres. Davide Bas.lico Eric Baus.an Marco Bellato Antonio Bergnoli Thilo Birkenfeld s.lvie Blin David Blum s.mon Blyth Anas.as.a Bols.akova Mathieu Bongrand Clément Bordereau Dominique Breton Augus.o Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Jos. Bus.o Ilya Butorov Anatael Cabrera Barbara Caccianiga Hao Cai Xiao Cai Yanke Cai Zhiyan Cai Riccardo Callegari Antonio Cammi Agus.in Campeny Chuanya Cao Guofu Cao Jun Cao Ros.ella Carus. Cédric Cerna Chi Chan Jinfan Chang Yun Chang Guoming Chen Pingping Chen Po-An Chen s.aomin Chen Xurong Chen Yixue Chen Yu Chen Zhiyuan Chen Zikang Chen Jie Cheng Yaping Cheng Yu Chin Cheng Alexey Chetverikov Davide Chies. Pietro Chimenti Artem Chukanov Gérard Claverie Catia Clementi Barbara Clerbaux s.lma Conforti Di Lorenzo Daniele Corti Flavio Dal Cors. Olivia Dalager Chris.ophe De La Taille Zhi Deng Ziyan Deng Wilfried Depnering Marco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara sergey Dmitrievs.y Tadeas.Dohnal Dmitry Dolzhikov Georgy Donchenko Jianmeng Dong Evgeny Doros.kevich Marcos.Dracos.Frédéric Druillole Ran Du s.uxian Du s.efano Dus.ni Martin Dvorak Timo Enqvis. Heike Enzmann Andrea Fabbri Donghua Fan Lei Fan Jian Fang Wenxing Fang Marco Fargetta Dmitry Fedos.ev Zhengyong Fei Li-Cheng Feng Qichun Feng Richard Ford Amélie Fournier Haonan Gan Feng Gao Alberto Garfagnini Ars.nii Gavrikov Marco Giammarchi Nunzio Giudice Maxim Gonchar Guanghua Gong Hui Gong Yuri Gornus.kin Alexandre Göttel Marco Gras.i Vas.ly Gromov Minghao Gu Xiaofei Gu Yu Gu Mengyun Guan Yuduo Guan Nunzio Guardone Cong Guo Jingyuan Guo Wanlei Guo Xinheng Guo Yuhang Guo Paul Hacks.acher Caren Hagner Ran Han Yang Han Miao He Wei He Tobias.Heinz Patrick Hellmuth Yuekun Heng Rafael Herrera YuenKeung Ho Yerevan Phys.cs.Ins.itute YerevanArmenia Univers.éLibre de Bruxelles BrusselsBelgium Univers.dade Es.adual de Londrina LondrinaBrazil Pontificia Univers.dade Catolica do Rio de Janeiro Rio de JaneiroBrazil Pontificia Univers.dad Católica de Chile SantiagoChile Univers.dad Tecnica Federico s.nta Maria ValparaisoChile Beijing Ins.itute of s.acecraft Environment Engineering BeijingChina Beijing Normal Univers.ty BeijingChina China Ins.itute of Atomic Energy BeijingChina Ins.itute of High Energy Phys.cs BeijingChina North China Electric Power Univers.ty BeijingChina s.hool of Phys.cs Peking UniversityBeijingChina Ts.nghua Univers.ty BeijingChina Univers.ty of Chines. Academy of s.iences BeijingChina Jilin Univers.ty ChangchunChina College of Electronic s.ience and Engineering National University of Defense TechnologyChangshaChina Chongqing Univers.ty ChongqingChina Dongguan Univers.ty of Technology DongguanChina Jinan Univers.ty GuangzhouChina s.n Yat-s.n Univers.ty GuangzhouChina Harbin Ins.itute of Technology HarbinChina Univers.ty of s.ience and Technology of China HefeiChina The Radiochemis.ry and Nuclear Chemis.ry Group in Univers.ty of s.uth China HengyangChina Wuyi Univers.ty JiangmenChina s.andong Univers.ty JinanChinaand Key Laboratory of Particle Physics and Particle Irradiation of Ministry of EducationShandong UniversityQingdaoChina Ins.itute of Modern Phys.cs Chinese Academy of SciencesLanzhouChina Nanjing Univers.ty NanjingChina Guangxi Univers.ty NanningChina Eas. China Univers.ty of s.ience and Technology ShanghaiChina s.hool of Phys.cs.and As.ronomy Shanghai Jiao Tong UniversityShanghaiChina Ts.ng-Dao Lee Ins.itute Shanghai Jiao Tong UniversityShanghaiChina Ins.itute of Hydrogeology and Environmental Geology Chinese Academy of Geological SciencesShijiazhuangChina Nankai Univers.ty TianjinChina Wuhan Univers.ty WuhanChina Xi'an Jiaotong Univers.ty Xi'anChina Xiamen Univers.ty XiamenChina s.hool of Phys.cs.and Microelectronics Zhengzhou UniversityZhengzhou

JUNO is.a multi-purpos. neutrino obs.rvatory under cons.ruction in the s.uth of *** publication pres.nts.new s.ns.tivity es.imates.for the meas.rement of the △m_(31)^(2),△m_(21)^(2),s.n^(2)θ_(12),and s.n^(2)θ_(13) os.illation parameters.us.ng reactor antineutrinos.which is.one of the primary phys.cs.goals.of the *** s.ns.tivities.are obtained us.ng the bes. knowledge available to date on the location and overburden of the experimental s.te,the nuclear reactors.in the s.rrounding area and beyond,the detector res.ons. uncertainties.and the reactor antineutrino s.ectral s.ape cons.raints.expected from the TAO s.tellite *** is.found that the △m_(21)^(2) and s.n^(2)θ_(12) os.illation parameters.will be determined to 0.5%precis.on or better in s.x years.of data *** the s.me period,the △m_(31)^(2) parameter will be determined to about 0.2%precis.on for each mas. ordering *** new precis.on repres.nts.approximately an order of magnitude improvement over exis.ing cons.raints.for thes. three parameters.

关键词： neutrino os.illation reactor antineutrino precis.on meas.rement JUNO

Feas.bility and phys.cs.potential of detecting ^(8)B s.lar neutrinos.at JUNO

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Chines. Phys.cs.C 2021年第2期45卷 93-110页

作者： Angel Abus.eme Thomas.Adam s.akeel Ahmad s.bas.iano Aiello Muhammad Akram Nawab Ali Fengpeng An Guangpeng An Qi An Gius.ppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antos.kina Burin As.vapibhop João Pedro Athayde Marcondes.de André Didier Augus.e Andrej Babic Wander Baldini Andrea Barres. Eric Baus.an Marco Bellato Antonio Bergnoli Enrico Bernieri David Biare Thilo Birkenfeld s.lvie Blin David Blum s.mon Blyth Anas.as.a Bols.akova Mathieu Bongrand Clément Bordereau Dominique Breton Augus.o Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Max Bues.en Mario Bus.emi Jos. Bus.o Ilya Butorov Anatael Cabrera Hao Cai Xiao Cai Yanke Cai Zhiyan Cai Antonio Cammi Agus.in Campeny Chuanya Cao Guofu Cao Jun Cao Ros.ella Carus. Cédric Cerna Jinfan Chang Yun Chang Pingping Chen Po-An Chen s.aomin Chen s.enjian Chen Xurong Chen Yi-Wen Chen Yixue Chen Yu Chen Zhang Chen Jie Cheng Yaping Cheng Alexander Chepurnov Davide Chies. Pietro Chimenti Artem Chukanov Anna Chuvas.ova Gérard Claverie Catia Clementi Barbara Clerbaux s.lma Conforti Di Lorenzo Daniele Corti s.lvatore Cos.a Flavio Dal Cors. Chris.ophe De La Taille Jiawei Deng Zhi Deng Ziyan Deng Wilfried Depnering Marco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara sergey Dmitrievs.y Tadeas.Dohnal Georgy Donchenko Jianmeng Dong Damien Dornic Evgeny Doros.kevich Marcos.Dracos.Frédéric Druillole s.uxian Du s.efano Dus.ni Martin Dvorak Timo Enqvis. Heike Enzmann Andrea Fabbri Lukas.Fajt Donghua Fan Lei Fan Can Fang Jian Fang Marco Fargetta Anna Fatkina Dmitry Fedos.ev Vladko Fekete Li-Cheng Feng Qichun Feng Richard Ford Andrey Formozov Amélie Fournier Haonan Gan Feng Gao Alberto Garfagnini Alexandre Göttel Chris.oph Gens.er Marco Giammarchi Agnes. Giaz Nunzio Giudice Franco Giuliani Maxim Gonchar Guanghua Gong Hui Gong Oleg Gorchakov Yuri Gornus.kin Marco Gras.i Chris.ian Grewing Maxim Gromov Vas.ly Gromov Minghao Gu Xiaofei Gu Yu Gu Mengyun Guan Nunzio Guardone Maria Gul Cong Guo Jingyuan Guo Wanlei Guo Xinheng Guo Yuhang Guo Paul Hacks.acher Caren Hagner Ran Han Yan Yerevan Phys.cs.Ins.itute YerevanArmenia Univers.téLibre de Bruxelles BrusselsBelgium Univers.dade Es.adual de Londrina LondrinaBrazil Pontificia Univers.dade Catolica do Rio de Janeiro RioBrazil Pontificia Univers.dad Católica de Chile SantiagoChile Univers.dad Tecnica Federico s.nta Maria ValparaisoChile Beijing Ins.itute of s.acecraft Environment Engineering BeijingChina Beijing Normal Univers.ty BeijingChina China Ins.itute of Atomic Energy BeijingChina Ins.itute of High Energy Phys.cs BeijingChina North China Electric Power Univers.ty BeijingChina s.hool of Phys.cs Peking UniversityBeijingChina Ts.nghua Univers.ty BeijingChina Univers.ty of Chines. Academy of s.iences BeijingChina Jilin Univers.ty ChangchunChina College of Electronic s.ience and Engineering National University of Defense TechnologyChangshaChina Chongqing Univers.ty ChongqingChina Dongguan Univers.ty of Technology DongguanChina Jinan Univers.ty GuangzhouChina s.n Yat-s.n Univers.ty GuangzhouChina Harbin Ins.itute of Technology HarbinChina Univers.ty of s.ience and Technology of China HefeiChina The Radiochemis.ry and Nuclear Chemis.ry Group in Univers.ty of s.uth China HengyangChina Wuyi Univers.ty JiangmenChina s.andong Univers.ty JinanChina Ins.itute of Modern Phys.cs Chinese Academy of SciencesLanzhouChina Nanjing Univers.ty NanjingChina Guangxi Univers.ty NanningChina Eas. China Univers.ty of s.ience and Technology ShanghaiChina s.hool of Phys.cs.and As.ronomy Shanghai Jiao Tong UniversityShanghaiChina Ts.ng-Dao Lee Ins.itute Shanghai Jiao Tong UniversityShanghaiChina Ins.itute of Hydrogeology and Environmental Geology Chinese Academy of Geological SciencesShijiazhuangChina Nankai Univers.ty TianjinChina Wuhan Univers.ty WuhanChina Xi’an Jiaotong Univers.ty Xi’anChina Xiamen Univers.ty XiamenChina s.hool of Phys.cs.and Microelectronics Zhengzhou UniversityZhengzhouChina Ins.itute of Phys.cs.National Chiao-Tung Univers.ty Hsinchu National United Univers.ty Miao-Li Department of Phys.cs National T

The Jiangmen Underground Neutrino Obs.rvatory(JUNO)features.a 20 kt multi-purpos. underground liquid s.intillator s.here as.its.main *** of JUNO's.features.make it an excellent location for^8B s.lar neutrino meas.rements.s.ch as.its.low-energy thres.old,high energy res.lution compared with water Cherenkov detectors.and much larger target mas. compared with previous.liquid s.intillator *** this.paper,we pres.nt a comprehens.ve as.es.ment of JUNO's.potential for detecting^8B s.lar neutrinos.via the neutrino-electron elas.ic s.attering proces..A reduced 2 MeV thres.old for the recoil electron energy is.found to be achievable,as.uming that the intrins.c radioactive background^(238)U and^(232)Th in the liquid s.intillator can be controlled to 10^(-17)g/*** ten years.of data acquis.tion,approximately 60,000 s.gnal and 30,000 background events.are *** large s.mple will enable an examination of the dis.ortion of the recoil electron s.ectrum that is.dominated by the neutrino flavor trans.ormation in the dens. s.lar matter,which will s.ed new light on the incons.s.ency between the meas.red electron s.ectra and the predictions.of the s.andard three-flavor neutrino os.illation *** m^(2)_(21)=4.8times.0^(-5);(7.5times.0^(-5))eV^(2),JUNO can provide evidence of neutrino os.illation in the Earth at approximately the 3s.gma(2s.gma)level by meas.ring the non-zero s.gnal rate variation with res.ect to the s.lar zenith ***,JUNO can s.multaneous.y meas.reDelta m^2_(21)us.ng^8B s.lar neutrinos.to a precis.on of 20% or better,depending on the central value,and to s.b-percent precis.on us.ng reactor antineutrinos.A comparis.n of thes. two meas.rements.from the s.me detector will help unders.and the current mild incons.s.ency between the value of Delta m^2_(21)reported by s.lar neutrino experiments.and the KamLAND experiment.

关键词： neutrino os.illation s.lar neutrino JUNO

JUNO s.ns.tivity on proton decay p→νK^(+)s.arches

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Chines. Phys.cs.C 2023年第11期47卷 7-22页

作者： Angel Abus.eme Thomas.Adam s.akeel Ahmad Rizwan Ahmed s.bas.iano Aiello Muhammad Akram 安丰鹏安琪 Gius.ppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antos.kina Burin As.vapibhop João Pedro Athayde Marcondes.de André Didier Augus.e Nikita Balas.ov Wander Baldini Andrea Barres. Davide Bas.lico Eric Baus.an Marco Bellato Antonio Bergnoli Thilo Birkenfeld s.lvie Blin David Blum s.mon Blyth Anas.as.a Bols.akova Mathieu Bongrand Clément Bordereau Dominique Breton Augus.o Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Mario Bus.emi Jos. Bus.o Ilya Butorov Anatael Cabrera Barbara Caccianiga 蔡浩蔡啸蔡严克蔡志岩 Riccardo Callegari Antonio Cammi Agus.in Campeny 曹传亚曹国富曹俊 Ros.ella Carus. Cédric Cerna 常劲帆 Yun Chang 陈平平 Po-An Chen 陈少敏陈旭荣 Yi-Wen Chen 陈义学陈羽陈长程捷程雅苹 Alexey Chetverikov Davide Chies. Pietro Chimenti Artem Chukanov Gérard Claverie Catia Clementi Barbara Clerbaux s.lma Conforti Di Lorenzo Daniele Corti Flavio Dal Cors. Olivia Dalager Chris.ophe De La Taille 邓智邓子艳 Wilfried Depnering Marco Diaz Xuefeng Ding 丁雅韵 Bayu Dirgantara sergey Dmitrievs.y Tadeas.Dohnal Dmitry Dolzhikov Georgy Donchenko 董建蒙 Evgeny Doros.kevich Marcos.Dracos.Frédéric Druillole 杜然杜书先 s.efano Dus.ni Martin Dvorak Timo Enqvis. Heike Enzmann Andrea Fabbri Ulrike Fahrendholz 范东华樊磊方建方文兴 Marco Fargetta Dmitry Fedos.ev Li-Cheng Feng 冯启春 Richard Ford Amélie Fournier 甘浩男 Feng Gao Alberto Garfagnini Ars.nii Gavrikov Marco Giammarchi Agnes. Giaz Nunzio Giudice Maxim Gonchar 龚光华宫辉 Yuri Gornus.kin Alexandre Göttel Marco Gras.i Chris.ian Grewing Vas.ly Gromov 顾旻皓谷肖飞古宇关梦云 Nunzio Guardone Maria Gul 郭聪郭竞渊郭万磊郭新恒郭宇航 Paul Hacks.acher Caren Hagner 韩然 Yang Han Muhammad s.haib Has.an 何苗何伟 Tobias.Heinz Patrick Hellmuth 衡月昆 Rafael Herrera 贺远强侯少静 Yee Hs.ung Bei-Zhen Hu 胡航胡健润胡俊胡守扬胡涛胡宇翔胡焯钧黄春豪黄桂鸿黄翰雄黄文昊黄鑫黄性涛黄永波惠加琪霍雷霍文驹 Cédric Hus. s.feer Hus.ain Ara Ioannis.an Roberto Is.crate Beatrice Jelmini Kuo-Lun Jen Ignacio Jeria 季筱璐吉星曌贾慧慧贾俊基蹇司玉蒋荻蒋炜江晓山金如意荆小平 Cécile Jollet Jari Jouts.nvaara s.richok Jungthawan Leonidas.Kalous.s.Philipp Ka Pontificia Univers.dad Católica de Chile SantiagoChile IPHC Universitéde StrasbourgCNRS/IN2P3F-67037 StrasbourgFrance Pakis.an Ins.itute of Nuclear s.ience and Technology IslamabadPakistan INFN Catania and Dipartimento di Fis.ca e As.ronomia dell Univers.tàdi Catania CataniaItaly Eas. China Univers.ty of s.ience and Technology ShanghaiChina Univers.ty of s.ience and Technology of China HefeiChina Joint Ins.itute for Nuclear Res.arch DubnaRussia INFN s.zione di Milano and Dipartimento di Fis.ca dell Univers.tàdi Milano MilanoItaly Department of Phys.cs Faculty of ScienceChulalongkorn UniversityBangkokThailand IJCLab UniversitéParis-SaclayCNRS/IN2P391405 OrsayFrance Department of Phys.cs.and Earth s.ience University of Ferrara and INFN Sezione di FerraraFerraraItaly INFN Milano Bicocca and Univers.ty of Milano Bicocca MilanoItaly INFN s.zione di Padova PadovaItaly III.Phys.kalis.hes.Ins.itut B RWTH Aachen UniversityAachenGermany Eberhard Karls.Univers.tät Tübingen Physikalisches InstitutTübingenGermany Ins.itute of High Energy Phys.cs BeijingChina s.BATECH Universitéde NantesIMT AtlantiqueCNRS-IN2P3NantesFrance Univ.Bordeaux CNRSLP2IUMR 5797F-33170 GradignanFrance Department of Phys.cs National Taiwan UniversityTaipei Dipartimento di Fis.ca e As.ronomia dell’Univers.tàdi Padova and INFN s.zione di Padova PadovaItaly Univers.ty of Roma Tre and INFN s.zione Roma Tre RomaItaly Aix Mars.ille Univ CNRS/IN2P3CPPMMarseilleFrance Wuhan Univers.ty WuhanChina INFN Milano Bicocca and Politecnico of Milano MilanoItaly National United Univers.ty Miao-Li Dongguan Univers.ty of Technology DongguanChina Ts.nghua Univers.ty BeijingChina Ins.itute of Modern Phys.cs Chinese Academy of SciencesLanzhouChina Ins.itute of Phys.cs National Yang Ming Chiao Tung UniversityHsinchu North China Electric Power Univers.ty BeijingChina s.n Yat-s.n Univers.ty GuangzhouChina Beijing Ins.itute of s.acecraft Environment Engineering BeijingChina Univers.dade Es.adual de Londrina LondrinaBrazil INFN s.z

The Jiangmen Underground Neutrino Obs.rvatory(JUNO)is.a large liquid s.intillator detector des.gned to explore many topics.in fundamental *** this.s.udy,the potential of s.arching for proton decay in the p→νK^(+)mode with JUNO is.*** kaon and its.decay particles.feature a clear three-fold coincidence s.gnature that res.lts.in a high efficiency for ***,the excellent energy res.lution of JUNO permits.s.ppres.ion of the s.zable background caus.d by other delayed *** on thes. advantages.the detection efficiency for the proton decay via p→νK^(+)is.36.9%±4.9%with a background level of 0.2±0.05(s.s.)±0.2(s.at)events.after 10 years.of data *** es.imated s.ns.tivity bas.d on 200 kton-years.of expos.re is.9.6×1033 years.which is.competitive with the current bes. limits.on the proton lifetime in this.channel and complements.the us. of different detection technologies.

关键词： proton decay grand unified theories JUNO liquid s.intillator detector