检索结果-南通市图书馆

Open Journal of Immunology 2017年第3期7卷 51-58页

作者： Dovonou Albert Comlan Alassani adébayo Cossi Attinsounon Cossi Angelo Saké Kadidjatou adè serge Ahoui Séraphin Degla Jivather Tchégnonsi Tognon Francis Zannou Djimon Marcel adè Gabriel Houngbé Fabien Departemental Teaching Hospital of Borgou Parakou Benin National Teaching Hospital Cotonou Benin

Goal: To describe the clinical and immunological characteristics in the HIV-infected patients at the antiretroviral treatment initiation. Methods: This was a descriptive and retrospective study on the cohort of the patients living with HIV followed at Parakou teaching hospital from the 1st January 2004 to the 31st December 2012. Persons under the age of 15 and the pregnant women have been excluded from the study. Results: The active file was composed of 988 patients under antiretroviral treatment. They were 339 men and 649 women. The sex ratio was 0.52. The average age of the patients was 35.49 ± 9.72 years. The immunodeficiency was profound with 57.65% of patients at the stage 3 of WHO and 42.35% at the stage 4. Opportunistic infections at the antiretroviral treatment initiation were dominated by oral candidiasis (30.16%), the diarrhea (20.45%) and zona (11.03%). Conclusion: HIV infection touched young adults who consult at an advanced stage of immunodeficiency.

关键词： Clinical Immunological HIV Parakou Benin

Helicobacter Pylori Infection: Epidemiological, Clinical and Pathological Aspects in a Digestive Endoscopy Unit and the Pathological Anatomy Service of Parakou in Benin Republic

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Gastroenterology 2023年第7期13卷 225-236页

作者： Khadidjatou Saké Marie Claire Ballè Luc Valère Codjo Brun Nonvignon Murielle Somitondji Cossi Angelo Attinsounon serge adè Cossi adébayo Alassani Lionel David Togbenon Comlan Albert Dovonou Marie Thérèse Akélé Akpo Department of Medicine Departmental University Hospital Center of Borgou Parakou Benin Pathological Anatomy and Cytology Service Departmental University Hospital Center of Borgou Parakou Benin Pathological Anatomy and Cytology Service Faculty of Health Sciences National Hospital and University Center Cotonou Benin

Introduction: Helicobacter pylori (Hp) infection is the most common bacterial infection in the world. World Health Organization has classified this bacterium as a Class I carcinogen. The objective of this work is to study the epidemiological, clinical and pathological aspects of Helicobacter pylori infection among adults in a digestive endoscopy unit and the pathological anatomy service of Parakou. Patients and Methods: This was a descriptive and analytical cross-sectional study conducted from January 2020 to September 2020 in the digestive endoscopy unit and pathological anatomy service at the Departmental University Hospital Center of Borgou. Patients aged 18 years and older, who had undergone a gastroscopy with biopsies and who gave their oral consent were included. Three antral biopsies and two fundic biopsies were performed. The search for Hp was done under an optical microscope after staining with hematoxylin eosin. Results: A total of 151 patients were included and 51.66% were infected with Hp. Their average age was 40.63 ± 15.32 years and the sex ratio was 0.9. Epigastric pain was the most reported symptom (71.01%). Endoscopically, the prevalence of erythematous gastropathy was 98.72%. The study of chronic Hp gastritis according to Sydney system had shown signs of activity in 100% of patients with Hp and glandular atrophy in 83.33% of them. Intestinal metaplasia and dysplasia accounted for 24.35% and 29.48% of cases, respectively. Factors associated with Hp infection were: absence of proton pump inhibitor intake prior to examination, absence of handwashing with soap and water before eating, erythematous aspect of gastritis on gastroscopy, absence of intestinal metaplasia of the fundus, active and chronic aspects of gastritis on histology. Conclusion: The frequency of Hp infection in hospitals among adults admitted to the Digestive Endoscopy Unit of Parakou is high. To reduce this prevalence, it will be necessary to act on the factors identified.

关键词： Helicobacter pylori Gastroscopy Pathological Anatomy Parakou Benin Republic

Discrimination of Chinese traditional soy sauces based on their physico-chemical properties

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Chemistry 2010年第6期53卷 1406-1413页

作者： KOKOT serge School of Physical and Chemical Sciences Queensland University of Technology

This work aimed to classify the categories (produced by different processes) and brands (obtained from different geographical origins) of Chinese soy *** variables of physico-chemical properties (density,pH,dry matter,ashes,electric conductivity,amino nitrogen,salt,viscosity and total acidity) of 53 soy sauce samples were *** measured data was submitted to such pattern recognition as cluster analysis (CA),principal component analysis (PCA),discrimination partial least squares (DPLS),linear discrimination analysis (LDA) and K-nearest neighbor (KNN) to evaluate the data patterns and the possibility of differentiating Chinese soy sauces between different categories and *** clusters corresponding to the two categories were obtained,and each cluster was divided into three subsets corresponding to three brands by the CA *** variables for LDA and KNN were selected by the Fisher F-ratio *** prediction ability of all classifiers was evaluated by *** the three supervised discrimination analyses,LDA and KNN gave 100% predications according to the sample category and brand.

关键词： physico-chemical property chemometrics pattern recognition soy sauce

Investigation of the pharmacokinetics and determination of certain cephalosporins in rabbit plasma by a kinetic spectrophotometric method with the aid of chemometrics

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2011年第5期54卷 827-834页

作者： KOKOT serge Chemistry Faculty of Science and Technology Queensland University of Technology

This paper describes a kinetic spectrophotometric method for simultaneous determination of three cephalosporin antibiotics,cephradine,cefaclor and cefixime,with the aid of chemometrics. The method relies on their oxidation with KMnO4 to produce green manganate with different kinetic rates in alkaline medium. The proposed method was successfully applied to a pharmacokinetic study of three cephalosporin antibiotics in rabbit plasma via intravenous injections. The results indicated that the amount of cephradine,cefaclor and cefixime were reduced rapidly in rabbit blood,showing clear dose-dependency and the half-life of cefixime (160 min) was longer than those of cephradine (60 min) and cefaclor (60 min).

关键词： pharmacokinetics cephalosporin cefaclor cefixime cephradine kinetic spectrophotometry chemometrics

Authentication of Cassia seeds on the basis of two-wavelength HPLC fingerprinting with the use of chemometrics

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2010年第2期21卷 213-216页

作者： serge Kokot School of Physical and Chemical Sciences Queensland University of TechnologyBrisbaneQld 4001Australia

High performance liquid chromatographic(HPLC) fingerprints of Cassia seed,a traditional Chinese medicine(TCM),were developed by means of the chromatograms at two wavelengths of 238 and 282 ***,the two data sets were combined into one *** application of principal component analysis(PCA) for this data matrix showed that the samples were clustered into four groups in accordance with the plant sources and preparation ***,partial least squares(PLS),back propagation artificial neural...

关键词： Two-wavelength HPLC fingerprinting Cassia seeds Chemometrics Authentication

Peat Accumulation and Early Carboniferous Environments of the Kizel Coal Basin,the Urals,Russia

在线全文

学校读者我要写书评

暂无评论

Acta Geologica Sinica(English Edition) 2022年第3期96卷 1098-1112页

作者： serge V.NAUGOLNYKH Geological Institute of Russian Academy of Sciences Pyzhevsky per.7119017 MoscowRussia

The lithological and geochemical composition and conditions of formation of the coal-bearing deposits of the Kizel Coal Basin in the Perm region of the Urals(central Russia)are described using the two most representative sections,Gubakha-Stary Most and Krestovaya Mountain,based on a detailed“layer-by-layer”*** characteristics of the Lower Carboniferous paleosols from fossil paleosol(FPS-)profiles of the studied region are *** attention is paid to the parent vegetation of the coal-forming processes,based on an analysis of both plant macrofossils and *** peat accumulation in conditions of permanent incoming of clastic material from the Paleo-Urals to the Kizel Basin was probably effective only in more or less stable environments,when the accumulated organic matter produced by plant mortmass was not dissolved by clastic ***,the conditions of coal-forming are reconstructed as a forest swamp,where the main dominants are represented by lycopodiopsids of the order Lepidodendrales,predominantly Lepidodendron *** plants in particular were the source of the initial organic matter for the peat(and later coal)of the Kizel Coal Basin.

关键词： paleobotany palynology coal lithology paleogeography Viséan Urals

Kuedinskie Kluchiki, a Unique Middle Permian Biota Locality as a Key-point for Reconstruction of Late Paleozoic Terrestrial Ecosystems of the Urals, Russia

在线全文

学校读者我要写书评

暂无评论

Acta Geologica Sinica(English Edition) 2024年第4期98卷 850-866页

作者： serge V.NAUGOLNYKH Geological Institute of Russian Academy of Sciences Pyzhevsky per.7119017 MoscowRussia

Field work focused on the Kuedinskie Kluchiki locality, Perm region, Urals, Russia, which contains a rich assemblage of diverse fossil organisms including higher plants(equisetophytes, pteridosperms, ginkgophytes, conifers, vojnovskyans) represented by stems, leaves and reproductive organs;invertebrates(mollusks, arthropods), and tetrapods(temnospondyl amphibians, seymouriamorphs, cotylosaurs, synapsids, diapsids), as well as bony fishes. General characteristics of the taxonomical composition of the Kuedinskie Kluchiki locality are given. A new peltaspermalean pteridosperm taxon, Compsopteris longipinnata sp. nov., and a voltzialean conifer Archaeovoltzia kuedensis sp. nov. are described. General considerations on the paleoecologic and paleogeographic conditions of the Kuedinskie Kluchiki locality origin are given.

关键词： paleobotany paleoecology taxonomy Lagerst?tten new taxa peltasperms conifers Wordian Cis-Urals

Pathogenic aspects of pulmonary complications in acute pancreatitis patients

在线全文

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2009年第2期8卷 186-192页

作者： serge Chooklin Department of Surgery Medical University

BACKGROUND:Experimental and clinical observations show that proinflammatory cytokines and oxidative stress are involved in the development of local and particularly systemic complications in acute pancreatitis (AP) patients. There are often pulmonary complications in such patients. The mechanisms through which lung injury is induced in AP are not fully clear. METHODS:In order to assess the role of activated neutrophils, pro- and anti-inflammatory cytokines and adhesion molecules at the onset and development of respiratory complications and respiratory failure, we measured the serum levels of pro-inflammatory (IL-1β, IL-6, IL-8, IL-18, TNF-α) and anti-inflammatory (IL-1ra, IL-10) cytokines in 51 AP patients who had been diagnosed with pancreatitis-associated lung injury with and without the development of organ dysfunction. RESULTS:When admitted to the hospital, severe AP patients had increased concentrations of IL-1β, IL-6, IL-8, IL-18, and TNF-α. The concentration of IL-18 alone was considerably increased in the patients who later developed respiratory failure. The onset of acute respiratory distress syndrome in the AP patients was accompanied by an increase in the level of anti-inflammatory cytokines, especially IL-10. It was noted that in severe lung injury, myeloperoxidase activity in the blood increased significantly, but still reflected the processes taking place in the lung parenchyma. Increase in the concentrations of adhesion molecules preceded the development of pulmonary infiltration with respiratory failure symptoms, which provoked endothelial dysfunction and determined the capillary surface permeability for neutrophils and ***:In the pathogenesis of respiratory complications in AP cytokines, chemokines and adhesion molecules, in particular IL-1β, IL-6, IL-8, IL-18, TNF-α, ICAM-1, and E-selectin play major roles. At IL-18 concentrations >650 pg/ml, AP patients are likely to develop pulmonary dysfunction (sensitivity 58%, specificity 100

关键词： acute pancreatitis pulmonary complications cytokines adhesion molecules

AN hp-FEM FOR SINGULARLY PERTURBED TRANSMISSION PROBLEMS

在线全文

学校读者我要写书评

暂无评论

Journal of Computational Mathematics 2017年第2期35卷 152-168页

作者： serge Nicaise Christos Xenophontos Université de Valenciennes et du Hainaut Cambrésis LAMAV FR CNRS 2956 Institut des Sciences et Techniques de Valenciennes F-59313 - Valenciennes Cedex 9 France Department of Mathematics and Statistics University of Cyprus P.O. Box 20537 Nicosia 1678 Cyprus

We perform the analysis of the hp finite element approximation for the solution to singularly perturbed transmission problems, using Spectral Boundary Layer Meshes. In [12] it was shown that this method yields robust exponential convergence, as the degree p of the approximating polynomials is increased, when the error is measured in the energy norm associated with the boundary value problem. In the present article we sharpen the result by showing that the hp-Finite Element Method （FEM） on Spectral Boundary Layer Meshes leads to robust exponential convergence in a stronger, more balanced norm. Several numerical results illustrating and extending the theory are also nresented.

关键词： Singularly perturbed transmission problem Boundary layers Interface layers,hp-FEM Balanced norm Exponential convergence.

Understanding the psychological aspects of the radicalisation process:a sociocognitive approach

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Forensic Sciences Research 2021年第2期6卷 115-123页

作者： serge Garcet Interpersonal Criminology and Victimology Department of CriminologyFaculty of LawUniversity of LiegeLiegeBelgium

Understanding the psychological dimensions underlying the radicalisation process is a con-siderable challenge in the context of the legal judicial treatment of perpetrators of acts of radical *** clinical and qualitative study is based on an analysis of legal expert interviews of people at different stages of the radicalisation *** highlights common psychological characteristics in personality,mechanisms of moral neutralisation and socio-cognitive and interpretive treatment during *** observations suggest the applicability of a model of cognitive-emotional transformation of self and meaning-building in radical violent engagement.

关键词： Forensic sciences forensic psychology radicalisation sociocognitive paradigm personality social cognition moral disengagement relative deprivati