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Epidemiology, Clinical and Paraclinical Presentations of Pulmonary Embolism: A Cross-Sectional Study in a Sub-Saharan Africa Setting

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Open Journal of Respiratory Diseases 2019年第3期9卷 89-99页

作者： Bertrand Hugo Mbatchou Ngahane Félicité Kamdem Silvain Raoul Simeni Njonnou Nina Chebou Anastase Dzudie serge arnold ebongue Bruno Tengang Fernando Kemta Lekpa Yacouba Mapoure Njankouo Sidick Mouliom Henri Roger Ngote Henry Luma Namme Douala General Hospital Douala Cameroon Faculty of Medicine and Pharmaceutical Sciences University of Douala Douala Cameroon Faculty of Medicine and Biomedical Sciences University of Yaounde 1 Yaounde Cameroon Military Hospital Douala Cameroon Centre des Maladies Respiratoires Douala Cameroon

Background: Venous thromboembolic (VTE) disease burden is increasing worldwide, representing a major cause of cardiovascular death and public health problem. Pulmonary embolism (PE) is the most serious clinical presentation of VTE. Epidemiological and clinical data on PE are still lacking in Africa, particularly in Cameroon. This study aimed at determining the clinical features as well as imaging presentation and outcome of pulmonary embolism. Methods: A cross-sectional study was carried out in three hospitals in Douala. We retrospectively reviewed patient records admitted for PE from January 2009 to May 2017. We collected data on epidemiology, clinical presentation, venous Doppler/pulmonary computed tomographic angiography (CTA), and outcome. Results: We included 103 patients (56 males) with PE. Their median age was 52 years. The main risk factors were obesity (49.5%), hypertension (35.0%), long trip (24.3%) and cancer (18.4%). The most frequent clinical presentations were dyspnoea (83.4%), chest pain (78.6%), and cough (40.8%). Additionally, pleural effusion (32.8%), atelectasis (25.7%) and pulmonary hyperlucency (20.0%) were the most frequent findings on chest X-ray. The main abnormalities found in electrocardiogram were sinus tachycardia (63.4%), S1Q3T3 aspect (37.6%) and right axial deviation (28.7%). Moreover, right cavities dilatation (26.0%), pulmonary artery hypertension (35.0%) and pulmonary artery dilatation (21.0%) were the main echocardiographic findings. Low-molecular-weight heparin (LMWH) was the initial anticoagulant in all cases. There were 19 (18.4%) in-hospital deaths, and the mean hospital stay was 8.5 ± 5 days. Conclusion: PE is not rare in our setting. Obesity, long trip and cancer are the main risk factors, while dyspnoea, chest pain and respiratory distress are the main clinical presentation for PE. LMWH remains the therapeutic agent of choice. Lastly, in-hospital mortality is very high.

关键词： Epidemiology Africa Venous Thromboembolism Symptoms

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Exploratory and Descriptive Study of the Kimberlite Massif of Boya-02 at Eastern Kasai in the Democratic Republic of Congo

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Journal of Geoscience and Environment Protection 2024年第1期12卷 130-144页

作者： arnold Onya Ngila Ivon Ndala Tshiwisa Ruben Koy Kasongo serge Diemo Alain Cibumba Cibumba Chamira Fwani Pambu Dona Kampata Mbwelele Centre National de Télédétection (CNT) Kinshasa The Democratic Republic of Congo Department of Exploration Faculty of Oil and Gas University of Kinshasa Kinshasa The Democratic Republic of Congo Geo-Hydro-Energy Research Group Department of Geosciences Faculty of Sciences and Technologies University of Kinshasa Kinshasa The Democratic Republic of Congo

The Boya-02 kimberlite was identified at depth by geophysical survey work (a single-probe AM survey in 1997 and a gravity survey in 2006) that De Beers DRC Exploration carried out around anomaly 193/172/0019. This anomaly located approximately 50 km southwest of the town of Mbuji-Mayi in the Kasaï-Oriental Province in the DRC should therefore be the subject of detailed exploration with the aim of better identifying and describing this kimberlite. Thus, through exploratory work and cross-checking of geophysical and geological data, the discovery of this Massif was made by drilling on the aeromagnetic anomaly 193/172/X298. Based on drilling, sampling and laboratory petrographic analysis reports, the Boya-02 kimberlite was classified among highly diluted re-sedimented volcaniclastic kimberlites (KVR), rich in olivine and incidentally in quartz and poor in juvenile substances. This kimberlite represents a deposit of very low economic interest following extremely high dilution. The Boya-02 kimberlite was modeled using ground magnetism data. It is a complex anomaly comprising 2 components with variable amplitude appearing on a subtly magnetized linear detail. The modeled dimensions of two components of this anomaly are 0.32 Ha and 0.2 Ha at depths of 32 m & 14 m for the deposits to the West and the East respectively. Garnet data for the Boya-02 occurrence reports a maximum Pmin value of 49.7 kbar (207 garnets). These data demonstrate the high diamond potential which assumes a conductive cratonic geotherm of 40 mWm2.

关键词： Exploratoire Massif Kimberlitique Kasaï Oriental

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Adsorption of Tartrazine onto Activated Carbon Based Cola Nuts Shells: Equilibrium, Kinetics, and Thermodynamics Studies

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Open Journal of Inorganic Chemistry 2021年第1期11卷 1-19页

作者： Dantio Nguela Christian Brice Ngomo Horace Manga Bénédoué serge arnold Kouotou Daouda Abega Aimé Victoire Ndongo Ndongo Alain Giresse Che Randy Nangah Ndi Julius Nsami Laboratory of Applied Physical and Analytical Chemistry Department of Inorganic Chemistry Faculty of Science University of Yaoundé I Yaoundé Cameroon

The uptake of tartrazine from its aqueous solution by powdered activated carbon prepared from cola nut shells chemically activated with potassium hydroxide (ACK) and phosphoric acid (ACP) has been investigated using kinetics models. Batch isotherm data were analysed with the pseudo-first order, pseudo-second order model as well as the intraparticle diffusion model. For structural elucidation, the materials were characterized using FTIR, XRD and SEM. These analyses revealed that the activated carbons (ACK and ACP) were predominantly mesoporous with several oxygen-containing functional groups dispersed on their surface. The reaction was systematically investigated under various experimental conditions such as contact time, adsorbent dose and pH. For the two adsorbents, the quantity adsorbed of 19.256 mg/g and 18.196 mg/g respectively for ACP and ACK at respective contact times of 5 and 10 min were obtained. The adsorption data were tested with the Langmuir, Freundlich models. Langmuir model was found to best describe the adsorption of tartrate ions with maximum monolayer adsorption capacities of 24.57 and 21.59 mg/g for ACP and ACK, respectively. Results analysis indicated clearly that the pseudo-second order kinetic rate model best fitted the experimental data and therefore was the adsorption controlling mechanism for both adsorbents. Thermodynamic studies revealed that the adsorption process was spontaneous and exothermic for ACP with increased randomness at the solid solution interface, then exothermic but non-spontaneous for ACK. The results show that these activated carbons could be an alternative for more costly adsorbents for the purpose of tartrate ions elimination.

关键词： Cola Nuts Shells Activated Carbon Adsorption Tartrazine

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