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Chinese Journal of Natural Medicines 2021年第1期19卷 56-62页

作者： Lim seong-Min Park Hae-Bin Jin jun-O Department of Medical Biotechnology Yeungnam UniversityGyeongsan 38541South Korea Shanghai Public Health Clinical Center Shanghai Medical CollegeFudan UniversityShanghai201508China

Astragalus membranaceus(***)is a widely used traditional herb in China and *** polysaccharides(AMP),which make up a major part of the root extract,have been shown to modulate immune modulations,especially activation of bone marrow-derived dendritic cells(BMDCs)and T ***,the immune stimulatory effect of AMP in the mouse in vivo and human peripheral blood DCs(PBDCs)has not been well *** this study,we found that intravenous(i.v.)injection of AMP in C57 BL/6 mice induced remarkable elevations in co-stimulatory and MHC class I and II molecule levels in the splenic DCs and its *** stimulatory effect of DCs by AMP was elevated 6 h after treatment,which rapidly decreased 18 h after ***,AMP promoted intracellular production of pro-inflammatory cytokines in spleen DC subsets,which contributed elevation of serum cytokine ***,the AMP promoted PBDC ***,these results demonstrate that AMP can be used as an immune stimulatory molecules in human and mouse.

关键词： Astragalus membranaceus polysaccharide Spleen dendritic cell Human peripheral blood dendritic cell

Visual outcomes after three different surgical procedures for correction of refractive error in patients with thin corneas

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International Journal of Ophthalmology(English edition) 2020年第6期13卷 970-977页

作者： Hye seong Hwang Hyun Jeong Lee seong jun Lee Jae-Hyung Kim Department of Ophthalmology Chungbuk National UniversityCheongjuChunbguk 28644Republic of Korea Korean Minjok Leadership Academy HoengseongGangwon 25268Republic of Korea Nuri Eye Clinic Daejeon 35234Republic of Korea Seoul Daabom Eye Center CheoungjuChungbuk 28644Republic of Korea

AIM:To investigate and compare the visual and refractive outcomes of small incision lenticule extraction(SMILE),laser assisted sub-epithelial keratomileusis(LASEK),and LASEK combined with corneal collagen cross-linking(LASEKCXL)surgery in patients with less than 500μm of central corneal thickness(CCT).METHODS:The retrospective medical records review was conducted on the patients with CCT less than 500μm treated with SMILE,LASEK,and *** was a total of 172 eyes,76 eyes were in the SMILE group,53 eyes in the LASEK group,and 43 eyes in the LASEK-CXL *** distance visual acuity(UDVA),spherical equivalent refraction(SE),and corneal haze were followed up in the three groups for 12 ***:At 12 mo postoperatively,there were no statistically significant differences in UDVA and in the absolute value of SE between the three *** predictability within±0.50 D in the SMILE group(85.5%)was significantly higher than in both the LASEK group(64.2%,P<0.01)and the LASEK-CXL group(69.8%,P=0.04).The efficacy index and safety index were not significantly different among the three *** haze at 12 mo postoperatively was higher in the LASEK-CXL group(27.9%)than in the SMILE group(2.6%,P<0.01)and in the LASEK group(7.5%,P<0.01).CONCLUSION:In patients with CCT less than 500μm,SMILE,LASEK,and LASEK-CXL appear to be effective for myopic *** them,SMILE surgery shows the highest predictability.

关键词： small incision lenticule extraction thin cornea laser assisted sub-epithelial keratomileusis collagen-cross linking visual acuity myopia

Gastric cancer patients at high-risk of having synchronous cancer

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World Journal of Gastroenterology 2006年第16期12卷 2588-2592页

作者： jun Ho Lee Ja seong bae Keun Won Ryu Jong Seok Lee Sook Ryun Park Chan Gyoo Kim Myoung Cheorl Kook Il Ju Choi Young Woo Kim Jae-Gahb Park Jae-Moon bae Research Institute & Hospital National Cancer Center809 Madul-dongIlsandong-guGoyang-siGyeonggi-do411-769Korea

AIM： To identify patients with a high-risk of having a synchronous cancer among gastric cancer patients. METHODS： We retrospectively analyzed the prospective gastric cancer database at the National Cancer Center, Korea from December 2000 to December 2004. The clinicopathological characteristics of patients with synchronous cancers and those of patients without synchronous cancers were compared. Multivariate analysis was performed to identify the risk factors for the presence of a synchronous cancer in gastric cancer patients. RESULTS： 111 of 3291 gastric cancer patients （3.4%） registered in the database had a synchronous cancer. Among these 111 patients, 109 had a single synchronous cancer and 2 patients had two synchronous cancers. The most common form of synchronous cancer was colorectal cancer （42 patients, 37.2%） followed by lung cancer （21 patients, 18.6%）. Multivariate analyses revealed that elderly patients with differentiated early gastric cancer have a higher probability of a synchronous cancer. CONCLUSION： Synchronous cancers in gastric cancer patients are not infrequent. The physicians should try to find synchronous cancers in gastric cancer patients, especially in the elderly with a differentiated early gastric

关键词： Synchronous cancer Gastric cancer Colorectal cancer

Rapid Preparation of Monolithic Columns for Capillary Electrochromatography Separation

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Chinese Chemical Letters 2006年第6期17卷 813-816页

作者： Wen jun GONG Yi jun ZHANG Yu Ping ZHANG seong Ho CHOI Henan Institute of Science and Technology Xinxiang 453003 Department of Chemistry Hannam University Daejon South Korea

Fritless packed silica gel columns were prepared using sol-gel technology, The part of a 75 μm i.d. capillary was filled with a mixture of methacryloxypropyltrimethoxysilane, toluene and hydrochloric acid. Four different photoinitiators such as benzoin methyl ether, Irgacure 819, Irgacure 1700 and Irgacure 1800 were added in the presence or absence of sodium dodecyl sulfate during the polymerization process. The above eight solutions were irradiated at 365 nm about 5-10 min to prepare the porous monolithic sol-gel columns by a one-step process.

关键词： Monolithic columns electrochromatography photopolymerized sol-gel.

Surface plasmon enhancement of photoluminescence in photo-chemically synthesized graphene quantum dot and Au nanosphere

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Nano Research 2016年第6期9卷 1866-1875页

作者： Byeongho Park Sun jun Kim Ji Soo Sohn Min Sik Nam Shinill Kang seong Chan jun School of Mechanical Engineering Yonsei University 50 Yonsei-ro Seodaemun-gu Seou1120-749 Republic of Korea

Graphene quantum dots （GQDs） are promising candidates for potential applications such as novel optoelectronic devices and bio-imaging. However, insufficient light absorption to exhibit their intriguing characteristics. The strong confinement of light caused by the Au nanoparticles as an antenna can considerably boost the light absorption. With the assistance of ultraviolet irradiation, we prepared bluish-green luminescent nanospheres by the hybridiza- tion of GQD and Au nanoparticles （GQD/Au）. These nanospheres showed a photoluminescence quantum yield of up to 26.9%. The GQD/Au nanospheres were synthesized using a solution of GQDs and HAuC14 by a photochemical method with the reduction of GQDs and the formation of metallic Au. The GQDs and Au nanopartides self-assembled and aggregated into nanospheres via aurophilicity and hydrogen bonding interactions. The average size of the GQD/Au nanospheres was found to be in the range of 150-170 nm, which is much larger than that of the pristine GQDs （4-7 nm）. The GQD/Au nanospheres exhibited an absorption band at 541 nm, which indicates the presence of Au in the nanospheres. The typical absorbance features of GQDs were observed near 236 and 303 nrn. The photoluminescence characteristics were investigated using the excitation and emission spectra. The GQD/Au nanospheres exhibited two emission peaks at 468 and 529 nm in the visible range. The green fluorescent peak located at 529 nm was newly generated by the hybridization. The GQD/Au nanospheres showed an emission efficiency which was two times more than that of the intrinsic GQDs. The reason for this increase was the surface plasmon resonance from the Au particles, which improved the fluorescence property of the resulting nanospheres. These nanospheres can be perceived as outstanding candidates for applications such as displays, optoelectronic devices, and imaging of the biological samples with high emission intensity.

关键词： graphene quantum dot gold nanosphere photoluminescence UV irradiation

High-concentration dispersions of exfoliated MoS2 sheets stabilized by freeze-dried silk fibroin powder

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Nano Research 2016年第6期9卷 1709-1722页

作者： HeungBo Sim JiYong Lee Byeongho Park Sun jun Kirn Shinill Kang ,WonHyoung Ryu seong Chan jun School of Mechanical Engineering Yonsei University Seoul 120-749 Republic of Korea

Liquid-phase exfoliation （LPE） is an attractive method for the scaling-up of exfoliated MoS2 sheets compared to chemical vapor deposition and mechanical cleavage. However, the MoS2 nanosheet yield from LPE is too small for practical applications. We report a facile method for the scaling-up of exfoliated MoS2 nanosheets using freeze-dried silk fibroin powders. Compared to MoS2 dispersion in the absence of silk fibroin powder, sonicated MoS2 dispersions with silk fibroin powder （MoSJSilk dispersion） show noticeably higher exfoliated MoS2 nanosheet yields, with suspended MoS2 concentrations in MoS2/Silk dispersions sonicated for 2 and 5 h of 1.03 and 1.39 ***-1, respectively. The MoS2 concentration in the MoS2/Silk dispersion after centrifugation above 10,000 rpm is more than four times that without the silk fibroin. The size of the dispersed silk fibroin is controlled by the change of centrifugation rate, showing the removal of silk fibroin above tens of micrometers in size after centrifugation at 2,000 rpm. Size-controlled silk fibroin biomolecules combined with MoS2 nanosheets are expected to increase the practical use of such materials in fields related to tissue engineering, biosensors and electrochemical electrodes. Atomic force microscopy and Raman spectroscopy provide the height of the MoS2 nanosheets spin-cast from MoS2/Silk dispersions, showing thicknesses of 3--6 nm. X-ray photoelectron spectroscopy and X-ray diffraction indicate that the outermost surface layer of the hydrophobic MoS2 crystals interact with oxygen-containing functional groups that exist in the hydrophobic part of silk fibroins. The amphiphilic properties of silk fibroin combined with the MoS2 nanosheets stabilize dispersions by enhancing solvent-material interactions. The large quantities of exfoliated MoS2 nanosheets suspended in the as-synthesized dispersions can be utilized for the fabrication of vapor and electrochemical devices requiring high MoS2 nanosheets contents.

关键词： MoS2 nanosheet liquid-phase exfoliation freeze-dried silk fibroin powder amount of suspended MoB2 sheet stabilized dispersion

Electrochemical characteristics of Al-Mg and Al-Mg-Si alloy in sea water

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中国有色金属学会会刊：英文版 2012年第S3期22卷 881-886页

作者： seong-jong KIM Seung-jun LEE Jae-yong JEONG Kyu-hwan KIM Division of Marine Engineering Mokpo Maritime University

Among Al alloys,particularly 5000 series Al Mg and 6000 series Al Mg Si often used as marine materials have excellent corrosion resistance,low melting point,and thereby showing recycling availability when compared to other *** experiments were conducted to select the most suitable material for marine *** electrochemical experiments were conducted in natural *** corrosion test was performed in many methods such as anodic/cathodic polarization and Tafel analysis using multi-channel potentio/galvanostat WMPG *** results,anodic and cathodic polarization behaviors indicate the characteristics of passive state and concentration polarization by reduction reaction in dissolved oxygen,which shows excellent electrochemical *** analysis results show no significant difference but 5052-O alloy of various alloy materials indicates the lowest corrosion current ***,5052-O Al alloy presents most anti-corrosion material in marine environment.

关键词： Al alloy ship electrochemical characteristics corrosion

Diagnosis of Middle Ear Diseases Based on Convolutional Neural Network

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Computer Systems Science & Engineering 2023年第8期46卷 1521-1532页

作者： Yunyoung Nam seong jun Choi Jihwan Shin Jinseok Lee Department of Computer Science and Engineering Soonchunhyang UniversityAsan31538Korea Department of Otolaryngology-Head and Nech Surgery Soonchunhyang University College of MedicineCheonan HospitalCheonan31151Korea Department of Biomedical Engineering Kyung Hee UniversityYonginKorea

An otoscope is traditionally used to examine the eardrum and ear canal.A diagnosis of otitis media(OM)relies on the experience of *** an examiner lacks experience,the examination may be difficult and *** paper presents an ear disease classification method using middle ear images based on a convolutional neural network(CNN).Especially the segmentation and classification networks are used to classify an otoscopic image into six classes:normal,acute otitis media(AOM),otitis media with effusion(OME),chronic otitis media(COM),congenital cholesteatoma(CC)and traumatic perforations(TMPs).The Mask R-CNN is utilized for the segmentation network to extract the region of interest(ROI)from otoscopic *** extracted ROIs are used as guiding features for the *** classification is based on transfer learning with an ensemble of two CNN classifiers:EfficientNetB0 and *** proposed model was trained with a 5-fold cross-validation *** proposed method was evaluated and achieved a classification accuracy of 97.29%.

关键词： Otitis media convolutional neural network acute otitis media otitis media with effusion chronic otitis media congenital cholesteatoma traumatic perforation Mask R-CNN

Adenoma arising from xanthoma in the transverse colon:a case report

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Gastroenterology Report 2023年第1期11卷 542-544页

作者： Yu Jin jung jun Lee seong jung Kim Ran Hong Department of Internal Medicine College of MedicineChosun UniversityGwangjuRepublic of Korea Department of Pathology College of MedicineChosun UniversityGwangjuRepublic of Korea

Introduction A xanthoma is a benign lesion consisting of foamy cells characterized by a highly vacuolated *** lesions can develop anywhere in the gastrointestinal tract but most often occur in the stomach,duodenum,or esophagus and very rarely in the colon[1].Gastric xanthoma shows a high incidence in gastric cancer patients and is reportedly an independent predictor of gastric cancer[2].Although adenomas associated with colorectal xanthoma were first reported in 1997,clear evidence supporting an association between xanthoma and colorectal adenoma or cancer is lacking[3].Furthermore,the association between adenoma and lipid deposits is unproven,and although adenoma has been found adjacent to or around xanthoma,this is more likely coincidental.

关键词： colon stomach adenoma

Improving electromechanical output of IPMC by high surface area Pd-Pt electrodes and tailored ionomer membrane thickness

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International Journal of Smart and Nano Materials 2014年第2期5卷 99-113页

作者： Viljar Palmre seong jun Kim David Pugal Kwang Kim Department of Mechanical Engineering University of Nevada-RenoRenoNVUSA Department of Mechanical Engineering University of Nevada-Las VegasLas VegasNVUSA

In this study,we attempt to improve the electromechanical performance of ionic polymer–metal composites(IPMCs)by developing high surface area Pd-Pt electrodes and tailoring the ionomer membrane *** proper electroless plating techniques,a high dispersion of palladium particles is achieved deep in the ionomer membrane,thereby increasing notably the interfacial surface area of *** membrane thickness is increased using 0.5 and 1 mm thick ionomer *** comparison,IPMCs with the same ionomer membranes,but conventional Pt electrodes,are also prepared and *** electromechanical,mechanoelectrical,electrochemical and mechanical properties of different IPMCs are characterized and *** electron microscopy-energy dispersive X-ray(SEM-EDS)is used to investigate the distribution of deposited electrode metals in the cross section of Pd-Pt *** experiments demonstrate that IPMCs assembled with millimeter thick ionomer membranes and newly developed Pd-Pt electrodes are superior in mechanoelectrical transduction,and show significantly higher blocking force compared to conventional type of *** blocking forces of more than 0.3 N were measured at 4V DC input,exceeding the force output of typical Nafion®117-based Pt IPMCs more than two orders of *** newly designed Pd-Pt IPMCs can be useful in more demanding applications,e.g.,in biomimetic underwater robotics,where high stress and drag forces are encountered.

关键词： ionic polymer-metal composite IPMC electroactive polymer palladium electrode