检索结果-南通市图书馆

Obesity Indices Related to Obstructive Sleep Apnea in Obese Adults

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Biosciences and Medicines 2017年第10期5卷 34-43页

作者： Jongwoo Kim seon yeong lee Department of Family Medicine Inje University Sanggye-Paik Hospital Seoul South Korea

Background: Obstructive Sleep Apnea (OSA) is prevalent in obese patients. OSA should be evaluated because it might increase mortality. We aimed to evaluate the risk for OSA in obese Korean adults, and to examine the obesity indices most strongly associated with OSA. Method: Anthropometric measurements, fat computed tomography (CT) and dual energy X-ray absorptiometry (DEXA) were performed in 30 obese patients. All patients were divided into low or high risk group of OSA using Berlin Questionnaire. We compared differences between the groups in obesity-related indices. Result: Eleven of the 30 patients (36.7%) were in the low OSA risk group and 19 (63.3%) were in the high OSA risk group. The correlation coefficients for BMI, neck circumference, and neck-to-height ratio × 100(%) in the high-risk group versus the low-risk group were 1.03, 1.96, and 4.04, respectively (P = 0.03). Conclusion: The obesity index most strongly associated with OSA was neck circumference to height ratio.

关键词： Obesity Sleep Apnea Obstructive Obesity Index Neck Circumference to Height Ratio

A novel cytokine consisting of the p40 and EBI3 subunits suppresses experimental autoimmune arthritis via reciprocal regulation of Th17 and Treg cells

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2022年第1期19卷 79-91页

作者： seon-yeong lee Su-Jin Moon Young-Mee Moon Hyeon-Beom Seo Jun-Geol Ryu A Ram lee Chae Rim lee Da-Som Kim Yang-Mi Her Jeong Won Choi Seung-Ki Kwok Sung-Hwan Park Mi-La Cho The Rheumatism Research Center The Catholic University of KoreaSeoulSouth Korea Division of Rheumatology Department of Internal MedicineSeoul St.Mary’s HospitalCollege of MedicineThe Catholic University of KoreaSeoulSouth Korea Department of Biomedicine&Health Sciences College of MedicineThe Catholic University of KoreaSeoulSouth Korea Department of Medical Lifescience College of MedicineThe Catholic University of KoreaSeoulSouth Korea These author contributed equally:seon-yeong lee Su-Jin MoonYoung-Mee Moon

OBJECTIVE:The interleukin(IL)-12 cytokine family is closely related to the development of T helper cells,which are responsible for autoimmune disease enhancement or ***-12 family members are generally heterodimers and share threeα-subunits(p35,p19,and p28)and twoβ-subunits(p40 and EBI3).However,aβ-sheet p40 homodimer has been shown to exist and antagonize IL-12 and IL-23 signaling ***,we assumed the existence of a p40-EBI3 heterodimer in nature and sought to investigate its role in immune ***:The presence of the p40-EBI3 heterodimer was confirmed by ELISA,immunoprecipitation,and western blotting.A p40-EBI3 vector and p40-EBI3-Fc protein were synthesized to confirm the immunological role of this protein in mice with collageninduced arthritis(CIA).The anti-inflammatory effects of p40-EBI3 were analyzed with regard to clinical,histological,and immune cell-regulating features in mice with ***:Clinical arthritis scores and the expression levels of proinflammatory cytokines(e.g.,IL-17,IL-1β,IL-6,and TNF-α)were significantly attenuated in p40-EBI3-overexpressing and p40-EBI3-Fc-treated mice with CIA compared to vehicle-treated mice with *** joint damage and vessel formation-related gene expression were also reduced by p40-EBI3 heterodimer *** vitro,the p40-EBI3-Fc protein significantly suppressed the differentiation of Th17 cells and reciprocally induced CD4+CD25+Foxp3+(regulatory T)cells.p40-EBI3 also inhibited osteoclast formation in a concentrationdependent ***:In this study,p40-EBI3 ameliorated proinflammatory conditions both in vivo and in *** propose that p40-EBI3 is a novel anti-inflammatory cytokine involved in suppressing the immune response through the expansion of Treg cells and suppression of Th17 cells and osteoclastogenesis.

关键词： cytokine p40-EBI3 Rheumatoid arthritis Autoimmune disease regulatory T cell

Plasma Wall Potentials with Secondary Electron Emissions up to the Stable Space-Charge-Limited Condition

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Plasma Science and Technology 2013年第11期15卷 1093-1099页

作者： Jongho seon Ensang lee School of Space Research Kyung Hee University Seocheon-dong Giheung-gu Yongin-si

Numerical solutions to floating plasma potentials for walls emitting secondary elec- trons are obtained for various surface materials. The calculations are made with plasma moment equations and the secondary electron emission coefficients, which were determined from recent laboratory experiments. The results estimate the wall potentials up to the physical conditions that allow stable plasma sheaths under the space-charge-limited condition. The materials often used in the laboratory, such as aluminum, silicon, boron, molybdenum, silicon dioxide, and alumina, are considered. The minimum wall potential before the onset of space-charge-limited emission is determined by the electron temperatures at which the effective secondary electron emission coefficient integrated over the velocity distributions is about 0.62. The corresponding potential is given by -eφ0 ,- 1.87kBT. The condition for space-charge-limited emission is newly found by numerically searching for all the stable sheaths. The new condition is -eφ0 - 0.95kBT, and this predicts a wall potential that is less negative than the previously found one. Calculation of the power dissipated to the wall for hydrogen plasmas shows that there is a large difference in terms of power dissipation among the considered materials in the temperature range 20-50 eV.

关键词： secondary electrons plasma sheath wall potential space-charge-limited emission

Reactive wetting phenomena of MgO-C refractories in contact with CaO-SiO_2 slag

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

中国有色金属学会会刊：英文版 2012年第S3期22卷 870-875页

作者： seon-Hwa HEO Kyuyong lee Yongsug CHUNG Department of Advanced Materials Engineering Korea Polytechnic University Department of Consilience Korea Polytechnic UniversitySiheung-City

Wetting phenomena between MgO C and CaO SiO2 slags were investigated by varying carbon content.A sessile drop technique was adopted to study the wetting phenomena in conjunction with a high speed camera for the observation of intrinsic wetting *** results show that the high content of SiO2 and the presence of Al2O3 in slags enhance the diffusion of Mg2+,leading to the promotion of reactive *** carbon in MgO C refractory impedes the penetration of slags by repelling the slag and slowing the diffusion of Mg2+.This accounts for the non-wetting behavior of the slag on MgO C refractory with 17% (mass fraction) carbon similar to that of graphite.

关键词： MgO-C refractory molten slags wetting penetration

Enhancing the Prediction of User Satisfaction with Metaverse Service Through Machine Learning

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2022年第9期72卷 4983-4997页

作者： seon Hong lee Haein lee Jang Hyun Kim Department of Applied Artificial Intelligence/Department of Human-Artificial Intelligence Interaction Sungkyunkwan UniversitySeoul03063Korea Department of Interaction Science/Department of Human-Artificial Intelligence Interaction Sungkyunkwan UniversitySeoul03063Korea

Metaverse is one of the main technologies in the daily lives of several people,such as education,tour systems,and mobile application ***,the number of users of mobile metaverse applications is increasing owing to the merit of accessibility *** provide an improved service,it is important to analyze online reviews that contain user *** previous studies have utilized traditional methods,such as the structural equation model(SEM)and technology acceptance method(TAM)for exploring user satisfaction,using limited survey *** methods may not be appropriate for analyzing the users of mobile *** overcome this limitation,several researchers perform user experience analysis through online reviews and star ***,some online reviews occasionally have inconsistencies between the star rating and the sentiment of the *** variation disturbs the performance of machine *** alleviate the inconsistencies,Valence Aware Dictionary and sEntiment Reasoner(VADER),which is a sentiment classifier based on lexicon,is *** current study aims to build a more accurate sentiment classifier based on machine learning with *** this study,five sentiment classifiers are used,such as Naïve Bayes,K-Nearest Neighbors(KNN),Logistic Regression,Light Gradient Boosting Machine(LightGBM),and Categorical boosting algorithm(Catboost)with three embedding methods(Bag-of-Words(BoW),Term Frequency-Inverse Document Frequency(TF-IDF),Word2Vec).The results show that classifiers that apply VADER outperform those that do not apply VADER,excluding one classifier(Logistic Regression with Word2Vec).Moreover,LightGBM with TF-IDF has the highest accuracy 88.68%among other models.

关键词： Metaverse ubiquitous computing user satisfaction online review big data VADER machine learning natural language processing

A Lightweight Certificate-Based Aggregate Signature Scheme Providing Key Insulation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2021年第11期69卷 1747-1764页

作者： Yong-Woon Hwang Im-yeong lee Department of Software Convergence in Soonchunhyang University Asan-si31538Korea

Recently,with the advancement of Information and Communications Technology(ICT),Internet of Things(IoT)has been connected to the cloud and used in industrial sectors,medical environments,and smart ***,if data is transmitted in plain text when collecting data in an IoTcloud environment,it can be exposed to various security threats such as replay attacks and data ***,digital signatures are *** integrity is ensured when a user(or a device)transmits data using a *** addition,the concept of data aggregation is important to efficiently collect data transmitted from multiple users(or a devices)in an industrial IoT ***,signatures based on pairing during aggregation compromise efficiency as the number of signatories *** signature methods(e.g.,identity-based and certificateless cryptography)have been *** methods pose key escrow and key distribution *** order to solve these problems,the use of aggregate signatures in certificate-based cryptography is being studied,and studies to satisfy the prevention of forgery of signatures and other security problems are being *** this paper,we propose a new lightweight signature scheme that uses a certificate-based aggregate signature and can generate and verify signed messages from IoT devices in an IoT-cloud *** this proposed method,by providing key insulation,security threats that occur when keys are exposed due to physical attacks such as side channels can be *** can be applied to create an environment in which data is collected safely and efficiently in IoT-cloud is environments.

关键词： Internet of things certificate-based aggregate signature key insulation cloud lightweight physical attack

ESG Discourse Analysis Through BERTopic: Comparing News Articles and Academic Papers

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2023年第6期75卷 6023-6037页

作者： Haein lee seon Hong lee Kyeo Re lee Jang Hyun Kim Department of Applied Artificial Intelligence/Department of Human-Artificial Intelligence Interaction Sungkyunkwan UniversitySeoul03063Korea Center for SW Education Hanyang UniversityAnsan15588Korea Department of Interaction Science/Department of Human-Artificial Intelligence Interaction Sungkyunkwan UniversitySeoul03063Korea

Environmental,social,and governance(ESG)factors are critical in achieving sustainability in business management and are used as values aiming to enhance corporate ***,non-financial indicators have been considered as important for the actual valuation of corporations,thus analyzing natural language data related to ESG is *** previous studies limited their focus to specific countries or have not used big *** methodologies are insufficient for obtaining potential insights into the best practices to leverage *** address this problem,in this study,the authors used data from two platforms:LexisNexis,a platform that provides media monitoring,and Web of Science,a platform that provides scientific *** big data were analyzed by topic *** modeling can derive hidden semantic structures within the *** this process,it is possible to collect information on public and academic *** authors explored data from a text-mining perspective using bidirectional encoder representations from transformers topic(BERTopic)—a state-of-the-art topic-modeling *** addition,changes in subject patterns over time were considered using dynamic topic *** a result,concepts proposed in an international organization such as the United Nations(UN)have been discussed in academia,and the media have formed a variety of agendas.

关键词： ESG BERTopic natural language processing topic modeling

Inhibition of poly(ADP-Ribose)polymerase:A promising strategy targeting pancreatic cancer with BRCAness phenotype

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2021年第11期13卷 1544-1550页

作者： Keun-yeong Jeong Haejun lee R&D Center Metimedi PharmaceuticalsIncheon 22006South Korea Department of Nuclear Medicine Gil Medical CenterIncheon 21565South Korea

The use of chemotherapeutic regimens for the treatment of pancreatic cancer is still limited because pancreatic cancer is usually diagnosed at an advanced stage as a refractory disease in which symptoms are difficult to recognize in the early ***,at advanced stages,there are important challenges to achieve clinical benefit and symptom resolution,even with the use of an expanded spectrum of anticancer ***,a point of reduced susceptibility to conventional chemotherapies by breast cancer susceptibility gene(BRCA)mutations led to a new perspective for overcoming the resistance of pancreatic cancer within the framework of increased genome ***(ADP-Ribose)polymerase(PARP)-1 is an enzyme that can regulate intrinsic functions,such as response to DNA ***,in an environment where germline mutations in BRCAs(BRCAness)inhibit homologous recombination in DNA damage,resulting in a lack of DNA damage response,a key role of PARP-1 for the adaptation of the genome instability could be further ***,we summarized the key functional role of PARP-1 in genomic instability of pancreatic cancer with the BRCAness phenotype and listed clinical applications and outcomes of PARP-1 inhibitors to highlight the importance of targeting PARP-1 activity.

关键词： Pancreatic cancer BRCAness Poly(ADP-Ribose)polymerase-1 PARylation Poly(ADP-Ribose)polymerase-1 inhibitor

CREEP BEHAVIOR OF Zr-1.5Nb-0.4Sn-0.1Fe-0.1Cu ALLOY

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Mechanica Solida Sinica 2008年第4期21卷 308-311页

作者： Ji Young Kim Kwang Su Na Yong Duck Kim Ji Hui Kim Kwon yeong lee Ki Nam Kim seon Jin Kim Division of Advanced Materials Science and Engineering Hanyang University133-791Korea Technical Research Center Sheet Products Design TeamHyundai Steel CompanyKodae-RiSongak-MyeonDangjin-GunChungnam167-32Korea

Creep behavior of the Zr-1.5Nb-0.4Sn-0.1Fe-0.1Cu alloy sheet is investigated from 300℃ to 400℃ in the stress range from 50 MPa to 180 MPa along the rolling direction. The measured strain rates range from 8.8 × 10^-10 s^-1 to 4.7 × 10^-7 s^-1. The activation energies are estimated to assess the creep deformation mechanisms in this alloy. The strain rate is slightly different at low stress, while it shows a distinct difference at high stresses. Stress exponents of this alloy increase with increasing applied stress at all testing temperatures. It is concluded that the creep deformation of the Zr-1.5Nb-0.4Sn-0.1Fe-0. 1 Cu alloy is controlled by the diffusion creep at low stress region and by the climbing of dislocations at high stress region.

关键词： creep zirconium alloy nuclear cladding