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World Journal of Clinical Cases 2022年第10期10卷 3078-3087页

作者： Jung Wan Choe Hyo Jung kim Jae seon kim Department of Internal Medicine Korea University Ansan HospitalKorea University College of MedicineAnsan 15355South Korea Department ofInternal Medicine Korea University Guro HospitalKorea University College of MedicineSeoul 08308South Korea Department ofInternal Medicine Korea University Guro Hospital2

BACKGROUND Radical resection is the only indicator associated with survival in extrahepatic cholangiocarcinoma(EHCC).however,limited data are available regarding the implications of dysplasia at the resection margin following *** To evaluate the prognostic significance of dysplasia-positive margins in patients diagnosed with *** We reviewed the records of patients who had undergone surgery for EHCC with curative intent between January 2013 and July *** retrospectively analyzed the clinicopathological data of 116 patients followed for longer than 3 *** status of resection margin was used to classify patients into negative low-grade dysplasia(LGD)and high-grade dysplasia(HGD)/carcinoma in situ(CIS)*** Based on postoperative status,72 patients underwent resection with negative margins,19 had LGD-positive margins,and 25 showed HGD/CIS-positive *** mean survival rates of the patients with negative margins,LGD margins,and HGD/CIS margins were 49.1±4.5,47.3±6.0,and 20.8±4.4 mo,respectively(P70 years and HGD/CIS-positive margins were significant independent factors for survival(hazard ratio=1.90 and 2.47,respectively).CONCLUSION HGD/CIS margin in resected EHCC is associated with a poor ***,the LGDpositive resection margin is not a significant indicator of survival in patients with EHCC.

关键词： Dysplasia Cholangiocarcinoma Survival Extrahepatic cholangiocarcinoma Low-grade dysplasia High-grade dysplasia

Tungsten-based nanocatalysts with different structures for visible light responsive photocatalytic degradation of bisphenol A

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Journal of Environmental Sciences 2024年第5期139卷 569-588页

作者： Hai Bang Truong Thi Thu Loan Doan Nguyen Tien hoang Nguyen Van Tam Minh kim Nguyen Le Gia Trung Jin Seog Gwag Nguyen Tien Tran Optical Materials Research Group Science and Technology Advanced InstituteVan Lang UniversityHo Chi Minh CityViet Nam Faculty of Applied Technology School of TechnologyVan Lang UniversityHo Chi Minh CityViet Nam The University of Da Nang University of Science and Technology54 Nguyen Luong BangDa NangViet Nam The University of Da Nang University of Science and Education459 Ton Duc Thang St.Lien ChieuDa Nang 550000Viet Nam Institute of Veterinary Science and Technology 31ha zoneTrau QuyGia LamHa Noi 12400Viet Nam Department of Physics Yeungnam UniversityGyeongsanGyeongbuk 38541Republic of Korea Center for Advanced Chemistry Institute of Research and DevelopmentDuy Tan University03 Quang TrungDa Nang 550000Viet Nam Faculty of Natural Sciences Duy Tan University03 Quang TrungDa Nang 550000Viet Nam

Environmental pollution,such as water contamination,is a critical issue that must be absolutely ***,three different morphologies of tungsten-based photocatalysts(WO_(3)nanorods,WO_(3)/WS_(2)nanobricks,WO_(3)/WS_(2)nanorods)are made using a simple hydrothermal method by changing the solvents(H_(2)O,DMF,aqueous HCl solution).The as-prepared nanocatalysts have excellent thermal stability,large porosity,and high *** results show all materials have good photocatalytic activity in aqueous media,with WO_(3)/WS_(2)nanorods(NRs)having the best activity in the photodegradation of bisphenol A(BPA)under visible-light *** may originate from increased migration of charge carriers and effective prevention of electron–hole recombination in WO_(3)/WS_(2)NRs,whereby this photocatalyst is able to generate more reactive·OH and·O_(2)^(–)species,leading to greater photocatalytic *** 99.6% of BPA is photodegraded within 60 min when using 1.5 g/L WO_(3)/WS_(2)NRs and 5.0 mg/L BPA at pH ***,the optimal conditions(pH,catalyst dosage,initial BPA concentration)for WO_(3)/WS_(2)NRs are also elaborately *** rod-like heterostructures are expressed as potential catalysts with excellent photostability,efficient reusability,and highly active effectivity in different types of *** particular,the removal efficiency of BPA by WO_(3)/WS_(2)NRs reduces by only 1.5% after five recycling runs and even reaches 89.1%in contaminated lake *** study provides promising insights for the nearly complete removal of BPA from wastewater or different water resources,which is advantageous to various applications in environmental remediation.

关键词： Photodegradation Bisphenol A Tungsten-based nanocatalyst Structure Nanorod

Maintenance of gut microbiome stability for optimum intestinal health in pigs——a review

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Journal of Animal Science and Biotechnology 2023年第3期14卷 853-863页

作者： Santi Devi Upadhaya In ho kim Department of Animal Resource and Science Dankook UniversityNo.29 AnseodongCheonan31116ChoongnamSouth Korea

Pigs are exposed to various challenges such as weaning,environmental stressors,unhealthy diet,diseases and infections during their lifetime which adversely affects the gut *** inability of the pig microbiome to return to the pre-challenge baseline may lead to dysbiosis resulting in the outbreak of ***,the maintenance of gut microbiome diversity,robustness and stability has been influential for optimum intestinal health after *** human and animal researches have focused on more holistic approaches to obtain a robust gut microbiota that provides protection against pathogens and improves the digestive physiology and the immune *** this review,we present an overview of the swine gut microbiota,factors affecting the gut microbiome and the importance of microbial stability in promoting optimal intestinal ***,we discussed the current understanding of nutritional interventions using fibers and pre/probiotics supplementation as non-antibiotic alternatives to maintain microbiota resilience to replace diminished species.

关键词： Microbial diversity Nutritional intervention Perturbation Resilience Swine gut microbiome stability

Clinical outcomes of endoscopic papillectomy of ampullary adenoma: A multi-center study

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World Journal of Gastroenterology 2022年第17期28卷 1845-1859页

作者： seong Ji Choi hong Sik Lee Jiyeong kim Jung Wan Choe Jae Min Lee Jong Jin Hyun Jai hoon Yoon Hyo Jung kim Jae seon kim ho Soon Choi Department of Internal Medicine Hanyang University College of MedicineSeoul 04763South Korea Division of Gastroenterology and Hepatology Department of Internal MedicineKorea University College of MedicineSeoul 02841South Korea Lab of Biostatistical Consulting and Research Medical Research Collaborating CenterIndustry-University Cooperation FoundationHanyang UniversitySeoul 04763South Korea

BACKGROUND Ampullary adenoma is a rare premalignant lesion,but its incidence is *** papillectomy has become the first treatment of choice for ampullary adenomas due to its safety and effectiveness,thereby replacing surgical ***,recurrence rates and adverse events after endoscopic papillectomy were reported in up to 30%of *** To review the long-term outcomes of endoscopic papillectomy and investigate the factors that affect these *** We retrospectively analyzed the data of patients who underwent endoscopic papillectomy for ampullary adenoma at five tertiary hospitals between 2013 and *** evaluated clinical outcomes and their risk *** definitions of outcomes were as follow:(1)curative resection:complete endoscopic resection without recurrence;(2)endoscopic success:treatment of ampullary adenoma with endoscopy without surgical intervention;(3)early recurrence:reconfirmed adenoma at the first endoscopic surveillance;and(4)late recurrence:reconfirmed adenoma after the first endoscopic *** A total of 106 patients were included for *** the included patients,81(76.4%)underwent curative resection,99(93.4%)had endoscopic success,showing that most patients with noncurative resection were successfully managed with *** patients(15.1%)had piecemeal resection,22 patients(20.8%)had shown positive/uncertain resection margin,11 patients(16.1%)had an early recurrence,13 patients(10.4%)had a late recurrence,and 6 patients(5.7%)had a *** multivariate analysis,a positive/uncertain margin[Odds ratio(OR)=4.023,P=0.048]and piecemeal resection(OR=6.610,P=0.005)were significant risk factors for early and late recurrence,*** resection was also a significant risk factor for non-curative resection(OR=5.424,P=0.007).Twenty-six patients experienced adverse events(24.5%).CONCLUSION Endoscopic papillectomy is a safe and effective treatment for ampullary ***

关键词： Endoscopic papillectomy Ampullary adenoma Clinical outcome Recurrence Adverse event

A novel electrospinning method for self-assembled tree-like fibrous scaffolds:Microenvironment-associated regulation of MSC behavior and bone regeneration

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Journal of Materials Science & Technology 2022年第20期115卷 52-70页

作者： Jeong In kim Ju Yeon kim Sung-ho Kook Jeong-Chae Lee Cluster for Craniofacial Development and Regeneration Research Institute of Oral Biosciences and School of DentistryJeonbuk National UniversityJeonju 54896Republic of Korea Department of Bionanosystem Engineering Jeonbuk National UniversityJeonju 54896Republic of Korea Department of Bioactive Material Sciences Research Center of Bioactive MaterialsJeonbuk National UniversityJeonju 54896Republic of Korea

Numerous studies highlight advantages of electrospun scaffolds in bone tissue engineering,in which cellular behavior is tightly affected by fiber topographical cues of ***,the classic electrospinning setup limits a desired presentation of biomimetic fibrous microenvironments that sense mechanosignaling and regulate stem cell *** aims of this study were to fabricate advanced asspun scaffolds presenting tree-like microfiber/nanonet networks and to evaluate their regulatory potentials on behavior of human mesenchymal stem cells(h MSCs)and bone *** we developed a novel electrospinning setup that allowed the presentation of patterned Trunk microfibers(TMF)and/or branched nanonet fibers(BNn Fs)in biomimetic fibrous *** the cellular mechanisms,anisotropichierarchical topography of TMF controlled behavior of h MSCs through focal adhesion formation and Yesassociated protein(YAP)induction,whereas BNn F disturbed such mechanosensing responses in the *** fiber microenvironment-related expression and nuclear localization of YAP *** correlated with the potentials of as-spun scaffolds to enhance osteogenic differentiation of the h MSCs and alveolar bone defect healing in an animal ***,this study provides an advanced approach of the modified electrospinning setup for presentation of biomimetic fibrillar microenvironments in as-spun scaffolds along with their application in stem cell behavior regulation and regenerative tissue engineering.

关键词： Electrospinning Advanced biomimetic scaffolds Stem cell behavior Mechanosensing Bone tissue engineering

ESG Discourse Analysis Through BERTopic: Comparing News Articles and Academic Papers

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Computers, Materials & Continua 2023年第6期75卷 6023-6037页

作者： Haein Lee seon hong Lee Kyeo Re Lee Jang Hyun kim Department of Applied Artificial Intelligence/Department of Human-Artificial Intelligence Interaction Sungkyunkwan UniversitySeoul03063Korea Center for SW Education Hanyang UniversityAnsan15588Korea Department of Interaction Science/Department of Human-Artificial Intelligence Interaction Sungkyunkwan UniversitySeoul03063Korea

Environmental,social,and governance(ESG)factors are critical in achieving sustainability in business management and are used as values aiming to enhance corporate ***,non-financial indicators have been considered as important for the actual valuation of corporations,thus analyzing natural language data related to ESG is *** previous studies limited their focus to specific countries or have not used big *** methodologies are insufficient for obtaining potential insights into the best practices to leverage *** address this problem,in this study,the authors used data from two platforms:LexisNexis,a platform that provides media monitoring,and Web of Science,a platform that provides scientific *** big data were analyzed by topic *** modeling can derive hidden semantic structures within the *** this process,it is possible to collect information on public and academic *** authors explored data from a text-mining perspective using bidirectional encoder representations from transformers topic(BERTopic)—a state-of-the-art topic-modeling *** addition,changes in subject patterns over time were considered using dynamic topic *** a result,concepts proposed in an international organization such as the United Nations(UN)have been discussed in academia,and the media have formed a variety of agendas.

关键词： ESG BERTopic natural language processing topic modeling

Malignant melanotic nerve sheath tumors in the spinal canal of psammomatous and non-psammomatous type: Two case reports

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World Journal of Clinical Cases 2022年第24期10卷 8735-8741页

作者： Jeong A Yeom You seon Song In Sook Lee In ho Han Kyung Un Choi Department of Radiology Pusan National University Yangsan HospitalYangsan 50612South Korea Department of Radiology Pusan National University HospitalBusan 49241South Korea Department of Neurosurgery Pusan National University HospitalBusan 49241South Korea Department of Pathology Pusan National University HospitalBusan 49241South Korea

BACKGROUND A malignant melanotic nerve sheath tumor(MMNST),previously known as a melanotic schwannoma,is a rare variant of a peripheral nerve sheath tumor composed of Schwann cells with melanotic *** a few reports of spinal MMNST have been *** SUMMARY In the first case,a 58-year-old woman presented with a history of low back pain and *** resonance imaging(MRI)and computed tomography(CT)of the lumbar spine revealed an intradural extramedullary mass lesion with amorphous linear *** tumor resection was performed and histological examination revealed a psammomatous melanotic *** the second case,a 72-year-old man presented with low back pain and *** of the thoracolumbar spine revealed an intramedullary mass lesion at the T11 vertebral body *** mass lesion was hypointense on T2WI and hyperintense on *** resection was performed and the histologic result was melanotic *** MMNST should be considered in the differential diagnosis when calcification or melanin is seen in an intradural spinal tumor.

关键词： Nerve sheath neoplasm Extramedullary Malignant Melanotic Magnetic resonance imaging Case reports

Possibility of Solid Hydrometeor Growth Zone Identification Using Radar Spectrum Width

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Advances in Atmospheric Sciences 2023年第2期40卷 317-332页

作者： Sung-ho SUH Eun-ho ChoI hong-Il kim Woonseon JUNG Flight Safety Technology Division NARO Space CenterKorea Aerospace Research Institute(KARI)508 Haban-roBongrae-myeonGoheung-gunJeollanam-do 59571Republic of Korea Research Applications Department National Institute of Meteorological Sciences33Seohobuk-roSeoqwipo-siJeju-do 63568Republic of Korea

In this study,the correlation between simulated and measured radar velocity spectrum width(σ_(v))is *** results show that the dendrites growth zones(DGZs)and needles growth zones(NGZs)mostly contain dendrites(DN)and needles(NE),***σ_(v) zones(1.11.2 m s^(-1),a differential reflectivity(ZDR)higher than 0 dB,and a cross-correlation coefficient(ρhv)less than *** contrast,prolate particles with relatively uniform shapes were observed in the NGZ withσ_(v)how that the DN exhibited a largerσ_(v) compared to the NE,and this observedσ_(v) was strongly dependent on the wind fluctuations(v’)due to turbulence or wind *** contrast,the NE exhibited a significantly smallσ_(v)~0.55 m s^(-1),which converges irrespective of v’.In addition,a strong correlation between the measuredσ_(v) values at five radar elevation angles(θ=6.2°,9.1°,13.1°,19°,and 80°)and those simulated in this study confirmed the significance of the analysis results.

关键词： spectrum width weather radar aerodynamic properties dendritic growth zone hydrometeor classifications

Surface-roughened current collectors for anode-free all-solid-state batteries

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Journal of Energy Chemistry 2022年第7期31卷 248-257,I0007页

作者： Donghee Gu Hyoungchul kim Jong-ho Lee Sangbaek Park Energy Materials Research Center Korea Institute of Science and Technology(KIST)Seoul 02792.Republic of Korea School of Civil Environmental and Architectural EngineeringKorea University.Seoul 02841.Republic of Korea Division of Nanoscience and Technology University of Science and Technology(UST)Seoul02792.Republicof Korea Department of Materials Science and Engineering Chungnam National UniversityDaejeon 34134.Republic of Korea

Anode-free all-solid-state batteries(AFASSBs), composed of a fully lithiated cathode and a bare current collector(CC) that eliminates excess lithium, can maximize the energy density(because of a compact cell configuration) and improve the safety of solid-state systems. Although significant progress has been made by modifying CCs in liquid-based anode-free batteries, the role of CCs and the mechanism of Li formation on CCs in AFASSBs are still unexplored. Here, we systematically investigate the effect of the surface roughness of the CCs on the Li plating/stripping behavior in AFASSBs. The results show that the moderately roughened CC substantially improves the Coulombic efficiency and cycle stability of AFASSBs owing to the increased contact points between the solid electrolyte and the roughened CC. In contrast, the excessively roughened CC deteriorates the performance owing to the contact ***, an ex situ interface analysis reveals that the roughened surface of the CC could suppress the interfacial degradation during the Li ion extraction from a sulfide solid electrolyte to a CC. This provides an indication to the origin that hinders the electrochemical performance of AFASSBs. These findings show the potential for the application of surface-engineered CCs in AFASSBs and provide guidelines for designing advanced CCs.

关键词： Anode-free Solid-state batteries Current collectors Surface roughness Li formation

A dynamic infiltration technique to synthesize nanolayered cathodes for high performance and robust solid oxide fuel cells

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Journal of Energy Chemistry 2022年第7期31卷 201-210,I0006页

作者： Saeed Ur Rehman ho-seon Song Hye-Sung kim Muhammad Haseeb Hassan Dong-Woo Joh Rak-Hyun Song Tak-Hyoung Lim Jong-Eun hong Seok-Joo Park Seung-Bok Lee High Temperature Energy Conversion Laboratory Korea Institute of Energy Research152Gajeong-roYuseong-gu.Daejeon34129.Republic of Korea Department of Advanced Energy and System Engineering University of Science and Technology.217 Gajeong-ro.Yuseong-gu.Daejeon 34113.Republicof Korea

Solution infiltration is a popular technique for the surface modification of solid oxide fuel cell(SOFC)***,the synthesis of nanostructured SOFC cathodes by infiltration is a tedious process that often requires several infiltration and high temperature(≥500℃)calcination ***,fabricating large-area nanostructured cathodes via infiltration still requires serious ***,we propose a facile and scalable urea assisted ultrasonic spray infiltration technique for nanofabrication of SOFC *** is demonstrated that by using urea as a precipitating agent,the calcination after each infiltration cycle can be omitted and the next infiltration can be performed just after a drying step(≤100℃).Finally,the precipitates can be converted into a desired catalyst phase in single calcination thus,a nanostructured cathode can be fabricated in a much faster *** is also shown that the low calcination temperature of the cathode(≤900℃)can produce highly durable SOFC performance even without employing a Ce_(0.9)Gd_(0.1)O_(2)(GDC)diffusion barrier layer which provides the ease of SOFC *** coupling with an ultrasonic spray technique,the urea assisted infiltration can be scaled up for any desired cathode ***_(0.6)Sr_(0.4)Co_(0.2)Fe_(0.8)O_(3) nanolayered cathode was fabricated and it was characterized by scanning electron microscope(SEM),X-ray diffraction(XRD),and transmission electron microscopy(TEM)*** showed the formation of a nanolayer cathode just after 5 cycles of the urea assisted infiltration while the XRD and TEM confirmed the phase and stoichiometric uniformity of the 100 nm cathode *** effectiveness of the newly developed technique was further verified by the stable operation of a GDC buffer layer free SOFC having an active cathode area of 25 cm^(2) during a 1200 h durability *** research outcomes propose urea assisted ultrasonic spray infiltration as a facile,scalable,and commercially viable method

关键词： Solid oxide fuel cell(SOFC) Cathode Infiltration Nanolayer Nanofabrication GDC barrier layer free SOFC