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Chicken soup for teaching and learning ESD

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World Journal of Gastroenterology 2011年第21期17卷 2618-2622页

作者： Eun Young Kim Seong Woo jeon Gwang Ha Kim Division of Gastroenterology Department of Internal MedicineCatholic University of Daegu School of Medicine Division of Gastroenterology Department of Internal MedicineKyungpook National University School of Medicine Department of Internal Medicine Pusan National University School of Medicine and Medical Research InstitutePusan National University Hospital

Endoscopic submucosal dissection(ESD) is becoming a popular procedure for the diagnosis and treatment of superficial mucosal lesions,and has the advantage of en bloc resection which yields a higher complete resection and remission rate compared to endoscopic mucosal resection(EMR).However,the learning process of this advanced endoscopic procedure requires a lengthy training period and considerable experience to be proficient.A well framed training protocol which is safe,effective,easily reproducible and cost-effective is desirable to teach *** addition,the training course may need to be tailored around settings such as ethnicity,culture,workload,and disease *** Asian countries with a large volume of early gastric lesions which need endoscopic treatment,endoscopists would be able to learn ESD expanding their skills from EMR to ESD under the supervision of ***,in Western countries due to the low incidence of superficial gastric tumors,trials have utilized simulator models to improve *** Korea,the Korean Society of Gastrointestinal Endoscopy(KSGE) is playing an important role in training many gastroenterologists who have shown an interest in performing ESD by providing an annual live demonstration and a nationwide tutoring *** purpose of this article is to introduce our ESD tutoring experience,review the published papers related to this topic,and propose several suggestions for future directions in teaching and learning ESD.

关键词： Endoscopic submucosal dissection Learning Teaching

Korean red ginseng promotes hippocampal neurogenesis in mice

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Neural Regeneration Research 2020年第5期15卷 887-893页

作者： Sun Ryu Hyongjun jeon Hee-Young Kim Sungtae Koo Seungtae Kim Korean Medicine Research Center for Healthy Aging Pusan National University49 Busandaehak-roMulgeum-eupYangsan-siGyeongsangnam-do 50612Republic of Korea Department of Korean Medical Science School of Korean MedicinePusan National University49 Busandaehak-roMulgeum-eupYangsan-siGyeongsangnam-do 50612Republic of Korea

Neurogenesis in the adult hippocampus plays a major role in cognitive ability of animals including learning and *** red ginseng (KRG) has long been known as a medicinal herb with the potential to improve learning and memory;however,the mechanisms are still ***,we evaluated whether KRG can promote cognitive function and enhance neurogenesis in the ***-week-old male C57BL/6 mice received 50 mg/kg of 5-bromo-2′-deoxyuridine (BrdU) intraperitoneally and 100 mg/kg of KRG or vehicle orally once a day for 14 ***,Rotarod and Morris water maze tests were performed and the brains were collected after the last behavioral *** in the numbers of BrdU- and BrdU/ doublecortin (DCX;a marker for neuronal precursor cells and immature neurons)-positive cells in the dentate gyrus and the gene expression of proliferating cell nuclear antigen (a marker for cell differentiation),cerebral dopamine neurotrophic factor and ciliary neurotrophic factor in the hippocampus were then ***-treated mice came down the pole significantly faster and stood on the rotarod longer than vehicle-treated *** Morris water maze test showed that KRG administration enhanced the learning and memory abilities *** also significantly increased BrdU- and BrdU/DCX-positive cells in the dentate gyrus as well as the proliferating cell nuclear antigen,cerebral dopamine neurotrophic factor and ciliary neurotrophic factor mRNA expression levels in the hippocampus compared to *** of KRG promotes learning and memory abilities,possibly by enhancing hippocampal *** study was approved by the Pusan National University Institutional Animal Care and Use Committee (approval ***-2016-1071) on January 19,2016.

关键词： bromodeoxyuridine cerebral dopamine neurotrophic factor ciliary neurotrophic factor doublecortin ginseng hippocampus Korean red ginseng learning memory neurogenesis proliferating cell nuclear antigen red ginseng

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System reliability analysis of downstream spillways based on collapse of upstream spillways

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International Journal of Agricultural and Biological Engineering 2015年第4期8卷 140-150,I0003页

作者： Won Choi jeongbae jeon Jinseon Park jeongJae Lee Seongsoo Yoon Department of Rural Systems Engineering College of Agriculture and Life SciencesSeoul National UniversitySeoul 151-921South Korea Department of Agricultural and Rural Engineering College of AgricultureLife and Environments SciencesChungbuk National UniversityChungbuk 362-763South Korea Department of Rural Systems Engineering Research Institute of Agriculture and Life SciencesCollege of Agriculture and Life SciencesSeoul National UniversitySeoul 151-921South Korea

Some agricultural reservoirs in South Korea are vulnerable to situations in which they are unable to function as reservoirs because of essential safety *** is because 70%of existing agricultural reservoirs were originally constructed more than 50 years ago;most of these reservoirs have not been maintained or managed since their initial *** the worst cases,reservoirs are connected to one another by short distances and/or the sizes of upstream reservoirs are larger than the sizes of downstream *** components of the reservoirs,such as their embankments,spillways,and water intake facilities,have been considered in order to understand the main factors associated with potential reservoir ***,this study aims to estimate the probability of failure in downstream spillways upon the collapse of upstream spillways(for reservoirs connected in series).A simple equation to calculate the rise in the water level in downstream spillways,which is caused by the collapse of upstream spillways,was *** equation was based on the discharge equation of an overflowing rectangular weir and the scaling law for continuous *** verify the proposed simple equation,the water level increments were compared with the simulated results of the commercial software FLOW-3D,which is an accurate computational fluid dynamics(CFD)program that is used for tracking free-surface *** values predicted through the simple formula were close to the simulated data(within a maximum prediction error of 5%).The values were updated to reflect the effects of hydraulic pressures on the walls of downstream spillways,thereby allowing the failure probabilities(due to overturning,sliding,and settlement)of the downstream spillways to be *** study found that the failure probabilities of independent components in reservoirs are significantly different from the systematic failure values observed in sequential modes.

关键词： failure probability collapse spillway discharge scaling law FLOW-3D

Abnormal medial rectus insertion presenting exotropia:a case report and review of the literature

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International Journal of Ophthalmology(English edition) 2016年第12期9卷 1852-1854页

作者： Heeyoung Choi Hyunkyu Kim Hyeshin jeon Department of Ophthalmology Pusan National University Hospital Medical Research Institute Pusan National University Hospital

I am Dr. Heeyoung Choi, from the Department of Ophthalmology of Pusan National University Hospital,Busan, Korea. I write to present a case report of abnormal medial rectus insertion presenting exotropia.

关键词： case Abnormal medial rectus insertion presenting exotropia length Figure

Machine Learning-Based Efficient Discovery of Software Vulnerability for Internet of Things

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Intelligent Automation & Soft Computing 2023年第8期37卷 2407-2419页

作者： So-Eun jeon Sun-Jin Lee Il-Gu Lee Department of Future Convergence Technology Engineering Sungshin Women’s UniversitySeoul02844Korea

With the development of the 5th generation of mobile communi-cation(5G)networks and artificial intelligence(AI)technologies,the use of the Internet of Things(IoT)has expanded throughout *** IoT networks have improved industrial productivity and convenience,they are highly dependent on nonstandard protocol stacks and open-source-based,poorly validated software,resulting in several security ***-ever,conventional AI-based software vulnerability discovery technologies cannot be applied to IoT because they require excessive memory and com-puting *** study developed a technique for optimizing training data size to detect software vulnerabilities rapidly while maintaining learning *** results using a software vulnerability classification dataset showed that different optimal data sizes did not affect the learning performance of the learning ***,the minimal data size required to train a model without performance degradation could be determined in *** example,the random forest model saved 85.18%of memory and improved latency by 97.82%while maintaining a learning accuracy similar to that achieved when using 100%of data,despite using only 1%.

关键词： Lightweight devices machine learning deep learning software vulnerability detection common weakness enumeration

Characteristics of odorous carbonyl compounds in the ambient air around a fishery industrial complex of Yeosu,Korea

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Journal of Environmental Sciences 2012年第10期24卷 1785-1789页

作者： Zhongkun Ma Junmin jeon Sangchai Kim Sangchul Jung Woobum Lee Seonggyu Seo Department of Environmental System Engineering Chonnam National University50 Daehak-roYeosu 550-749Republic of Korea Department of Civil&Environmental Engineering Suncheon First CollegeSan 9-3 Dokwol-DongSuncheon 540-744Republic of Korea Department of Environmental Education Molcpo National University61 Dorim RiCheonggye MyeonMuan 534-729Republic of Korea Department of Environmental Engineering Sunchon National University315 Maegok-DongSuncheon 540-742Republic of Korea

In this study, the amounts of odorous carbonyl compounds （OCCs） including acetaldehyde （Acet-A）, propionaldehyde （Pron-A）, butylaldehyde （Buty-A）, iso-valeric aldehyde （Iso-Vale-A） and n-valeric aldehyde （N-Vale-A） emitted from a fishery industrial complex near the exhibition facilities of ＂Expo 2012 Yeosu Korea＂ were measured. Acet-A was found to be the most abundant OCC, and the total concentrations of the OCCs were the highest in the summer. However, due to vehicular exhaust and photochemical reactions, the concentrations of some of the OCCs presented their highest levels in the fall. A significant correlation between Acet-A and Buty-A was found at the major fishery facilities （r = 0.816, p = 1.87E-15, n = 60） and at the border areas （r = 0.809, p = 3.40E-12, n = 48） of this fishery industrial complex. The concentrations of OCCs at the border areas were not worse than those at the urban areas in other places, indicating that the concentrations of ambient OCCs at the border areas were not greatly influenced by manmade activities.

关键词： fishery industrial complex odorant carbonyl compounds acetaldehyde seasonal variation

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Effect of the Bottom Topography on Tsunami Propagation in the East (Japan) Sea

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China Ocean Engineering 2008年第2期22卷 277-290页

作者： CHOI Byung-Ho PELINOVSKY Efim jeon Chul-Kyoo KIM Kyeong-Ok Department of Civil and Environmental Engineering Sungkyunkwan University Department of Nonlinear Geophysical Processes Institute of Applied PhysicsNizhny Novgorod 603950 Russia

A study of tsunami events in the East （Japan） Sea using continuous Galerkin finite element model, aiming at reproducing tsunami waves generated by underwater earthquakes in 1983 and 1993 respectively has been performed focusing on the geographic extent of a topographic feature in the East （Japan） Sea. Numerical models can be the proper tools to study the combined effects of realistic topography. Subsequently, using the FEM based two-dimensional model we have simulated the smoothed and flattened topographic effects by removal of Yamato Rise and seamounts for the cases of tthe 1983 Central region earthquake tsunami and the 1993 southwestern Hokkaido earthquake tsunami. The results have shown that there will be higher tsunamis along the eastern coasts of Korea in general except some areas, like Sokcho with removal of topographic highs, thus providing complicated bottom topography of the East （Japan） Sea as effective tsunami energy scattering.

关键词： Yamato Rise 1983 central East (Japan) Sea tsunami 1993 southwestern Hokkaido tsunami

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Work up for the clopidogrel hypersensitivity that led to recognising the undi- agnosed myelodysplastic syndrome

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Journal of Geriatric Cardiology 2016年第3期13卷 274-276页

作者： Yoo Sang Baek Jung Woo Lee Jiehyun jeon Department of Dermatology College of Medicine Korea University Seoul South Korea

Antiplatelet therapy with clopidogrel is widely used as a preventive strategy in patients with acute coronary syn- drome, particularly after stent *** mani- festations of clopidogrel hypersensitivity reaction have been reported including cutaneous,and hematologic symp- toms[31 as well as fatal reactions including thrombotic throm- bocytopenic purpura （TTP）.

关键词： Clopidogrel Hypersensitivity Myelodysplastic syndrome

Refining the American Urological Association and American Society for Radiation Oncology guideline for adjuvant radiotherapy after radical prostatectomy using the pathologic Gleason score

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Asian Journal of Andrology 2017年第1期19卷 20-25页

作者： Wan Song Young Suk Kwon Seong Soo jeon Isaac Yi Kim Section of Urologic Oncology Rutgers Cancer Institute of New Jersey Rutgers The State University of New Jersey New Brunswick NJ 08903 USA Department of Urology Samsung Medical Center Sungkyunkwan University School of Medicine Seoul South Korea.

Recently, it has been suggested that the guideline for adjuvant radiotherapy （ART） following radical prostatectomy （RP） sponsored by the American Urological Association and American Society for Radiation Oncology （AUA/ASTRO） may result in a significant overtreatment. Thus, the objective of the present study was to refine the AUA/ASTRO guideline for ART in patients at risk for biochemical recurrence （BCR） after RP. To this end, we reviewed our prospectively maintained database and selected 193 patients who met the AUA/ASTRO ART criteria. With a median follow-up of 24.0 months, BCR rate was 17.6% （34/193）. When stratified by the Gleason score, BCR rate in men with Gleason score 6 was 6.8%. There was no significant association between BCR-free survival and surgical margin （P= 0.690） and pathologic stage （P= 0.353） in patients with the Gleason score 6. However, in patients with positive surgical margins （PSMs）/pathologic stage ≥T3, there was a significant difference in BCR-free survival according to Gleason score （≤7 vs8-10, P= 0.047）. Multivariate Cox regression analysis demonstrated that pathologic stage ≥T3 （HR = 2.106; P = 0.018）, PSMs （HR = 2.411; P = 0.003）, and pathologic Gleason score 8-10 （HR = 4.715; P 〈 0.001） were independent predictors of BCR after RP. Therefore, in addition to pathologic stage 〉T3 and PSMs, Gleason score 8-10 predicts 8CR after RP. In patients with Gleason score 6, observation rather than ART may be more appropriate regardless of stage and surgical margin status.

关键词： adjuvant radiotherapy biochemical recurrence radical prostatectomy