检索结果-南通市图书馆

Periportal thickening on magnetic resonance imaging for hepatic fibrosis in infantile cholestasis

World Journal of Gastroenterology 2020年第21期26卷 2821-2830页

作者： Myung Hwan Lee Hyun joo Shin Haesung Yoon seok joo han Hong Koh Mi-Jung Lee Department of Radiology Severance HospitalSeverance Pediatric Liver Disease Research GroupResearch Institute of Radiological ScienceYonsei University College of MedicineSeoul 03722South Korea Department of Surgery Severance HospitalSeverance Pediatric Liver Disease Research GroupYonsei University College of MedicineSeoul 03722South Korea Division of Gastroenterology Hepatology and NutritionDepartment of PediatricsSeverance Children’s HospitalSeverance Pediatric Liver Disease Research GroupYonsei University College of MedicineSeoul 03722South Korea

BACKGROUND Untreated neonatal cholestasis can progress to liver cirrhosis and end stage liver disease in infancy due to prolonged hepatocyte and biliary tree injury and may require liver ***,non-invasive evaluation of hepatic fibrosis is important in infants with *** To investigate the usefulness of periportal thickening(PT)measured on liver magnetic resonance imaging(MRI)for the assessment of hepatic fibrosis in infants with cholestasis including biliary atresia(BA).METHODS This retrospective study included infants less than 6 mo who underwent liver MRI and biopsy for the evaluation of infantile *** and spleen size were measured on *** assessment was based on aspartate transaminase to platelet ratio index(APRI).The grade of histopathologic fibrosis was assessed by the METAVIR grading *** and diagnostic performance of PT,normalized spleen size ratio(SR,using the upper normal size limit),and APRI for diagnosing hepatic fibrosis were obtained by receiveroperating characteristic(ROC)curve *** A total of 155 patients were included,110 of which were diagnosed with *** age at the time of MRI was 57.6±34.4 *** were positive correlations between fibrosis grade and PT and SR,even after adjusting age(all,Phan 0.741(95%CI:0.664–0.808)for SR and 0.712(95%CI:0.634–0.782)for APRI(both,P<0.001).For the diagnosis of cirrhosis(F4),the area under the ROC curve was the highest with SR as 0.790(95%CI:0.718–0.852).CONCLUSION Liver MRI findings of PT and SR are useful to assess clinically significant hepatic fibrosis(F2 and higher)in infants with cholestasis including BA.

关键词： Infants Cholestasis Biliary atresia Liver Fibrosis Magnetic resonance imaging

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Liver intravoxel incoherent motion diffusion-weighted imaging for the assessment of hepatic steatosis and fibrosis in children

引用

World Journal of Gastroenterology 2018年第27期24卷 3013-3020页

作者： Hyun joo Shin Haesung Yoon Myung-joon Kim seok joo han Hong Koh Seung Kim Mi-Jung Lee Department of Radiology Severance Hospital Severance Pediatric Liver Disease Research Group Research Institute of Radiological Science Yonsei University College of Medicine Department of Surgery Severance Hospital Severance Pediatric Liver Disease Research Group Yonsei University College of Medicine Division of Gastroenterology Hepatology and Nutrition Department of Pediatrics Severance Children's Hospital Severance Pediatric Liver Disease Research Group Yonsei University College of Medicine

AIM To evaluate the correlation between intravoxel incoherent motion(IVIM) diffusion-weighted imaging(DWI) parameters and the degree of hepatic steatosis and fibrosis in *** This retrospective study was approved by the institutional review board. The children(≤ 18 years) who underwent liver IVIM DWI with 8 b-values under the suspicion of hepatic steatosis or fibrosis from February 2013 to November 2016 were included. Subjects were divided into normal, fatty liver(FAT), and fibrotic liver(FIB) groups. The slow diffusion coefficient(D), fast diffusion coefficient(D*), perfusion fraction(f), and apparent diffusion coefficient(ADC) were measured. MR proton density fat fraction(PDFF), MR elastography(MRE), and IVIM values were *** A total of 123 children(median age of 12 years old, range: 6-18 years) were included, with 8 in the normal group, 93 in the FAT group, and 22 in the FIB group. The D* values were lower in the FIB group compared with those of the normal(P = 0.015) and FAT(P = 0.003) groups. The f values were lower in the FIB group compared with the FAT group(P = 0.001). In multivariate analyses, PDFF value was positively correlated with f value(β = 3.194, P < 0.001), and MRE value was negatively correlated with D* value(β =-7.031, P = 0.032). The D and ADC values were not influenced by PDFF or MRE *** In liver IVIM DWI with multiple b-values in children, there was a positive correlation between hepatic fat and blood volume, and a negative correlation between hepatic stiffness and endovascular blood flow velocity, while diffusion-related parameters were not affected.

关键词： Intravoxel incoherent motion Diffusionweighted imaging Fibrosis Fatty liver Pediatrics

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Predicting gastroesophageal varices through spleen magnetic resonance elastography in pediatric liver fibrosis

引用

World Journal of Gastroenterology 2019年第3期25卷 367-377页

作者： Haesung Yoon Hyun joo Shin Myung-joon Kim seok joo han Hong Koh Seung Kim Mi-Jung Lee Department of Radiology Severance Hospital Severance Pediatric Liver Disease Research Group Research Institute of Radiological Science Yonsei University College of Medicine Department of Surgery Severance Hospital Severance Pediatric Liver Disease Research Group Yonsei University College of Medicine Division of Gastroenterology Hepatology and Nutrition Department of Pediatrics Severance Children's Hospital Severance Pediatric Liver Disease Research Group Yonsei University College of Medicine

BACKGROUND A recent retrospective study confirmed that hepatic stiffness and splenic stiffness measured with magnetic resonance elastography(MRE) are strongly associated with the presence of esophageal varices. In addition, strong correlations have been reported between splenic stiffness values measured with MRE and hepatic venous pressure gradients in animal models. However, most studies have been conducted on adult populations, and previous pediatric MRE studies have only demonstrated the feasibility of MRE in pediatric populations, while the actual clinical application of spleen MRE has been *** To assess the utility of splenic stiffness measurements by MRE to predict gastroesophageal varices in *** We retrospectively reviewed abdominal MRE images taken on a 3 T system in pediatric patients. Patients who had undergone Kasai operations for biliary atresia were selected for the Kasai group, and patients with normal livers and spleens were selected for the control group. Two-dimensional spin-echo echoplanar MRE acquisition centered on the liver, with a pneumatic driver at 60 Hz and a low amplitude, was performed to obtain hepatic and splenic stiffness values. Laboratory results for aspartate aminotransferase to platelet ratio index(APRI) were evaluated within six months of MRE, and the normalized spleen size ratio was determined with the upper normal size limit. All Kasai group patients underwent gastroesophageal endoscopy during routine follow-up. The MannWhitney U test, Kendall's tau b correlation and diagnostic performance analysis using the area under the curve(AUC) were performed for statistical *** The median spleen MRE value was 5.5 kPa in the control group(n = 9, age 9-18 years, range 4.7-6.4 kPa) and 8.6 kPa in the Kasai group(n = 22, age 4-18 years,range 5.0-17.8 kPa). In the Kasai group, the APRI, spleen size ratio and spleen MRE values were higher in patients with portal hypertension(n = 11) than in patients without(n =

关键词： Biliary atresia Magnetic resonance elastography Kasai operation Splenic stiffness Portal hypertension

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Primary intestinal lymphangiectasia diagnosed by capsule endoscopy and double balloon enteroscopy

引用

World Journal of Gastrointestinal Endoscopy 2011年第11期3卷 235-240页

作者： Tak Geun Oh joo Won Chung Hee Man Kim seok-joo han Jin Sung Lee Jung Yeob Park Si Young Song Division of Gastroenterology Department of Internal MedicineYonsei Institute of GastroenterologyYonsei University College of MedicineSeoul 120-752South Korea epartment of Pediatric Surgery Yonsei University College of MedicineSeoul 120-752South Korea Department of Pediatrics Yonsei University College of MedicineSeoul 120-752South Korea Division of Gastroenterology Department of Internal MedicineBrain Korea 21 Project for Medical Science and Severance Biomedical Science InstituteYonsei University College of MedicineSeoul 120-752South Korea

Primary intestinal lymphangiectasia(PIL)is a rare disorder characterized by dilated intestinal lymphatics and the development of protein-losing *** with PIL develop hypoalbuminemia,hypocalcemia,lymphopenia and hypogammaglobulinemia,and present with bilateral lower limb edema,fatigue,abdominal pain and *** reveals diffusely elongated,circumferential and polypoid mucosae covered with whitish enlarged villi,all of which indicate intestinal *** is conf irmed by characteristic tissue pathology,which includes dilated intestinal lymphatics with diffusely swollen mucosa and enlarged *** prevalence of PIL has increased since the introduction of capsule *** etiology and prevalence of PIL remain *** studies have reported that several genes and regulatory molecules for lymphangiogenesis are related to *** report the case of a patient with PIL involving the entire small bowel that was confirmed by capsule endoscopy and double-balloon enteroscopy-guided tissue pathology who carried a deletion on chromosome *** relationship between this deletion on chromosome 4 and PIL remains to be investigated.

关键词： Capsule endoscopy Double balloon enteroscopy Chromosome deletion Chromosome 4q25 Primary intestinal lymphangiectasia

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Synthesis of high-performance nickel hydroxide nanosheets/gadolinium doped-α-MnO_(2) composite nanorods as cathode and Fe_(3)O_(4)/GO nanospheres as anode for an all-solid-state asymmetric supercapacitor

引用

Journal of Energy Chemistry 2022年第1期31卷 475-484,I0013页

作者： Milan Babu Poudel han joo Kim Department of Convergence Engineering Technology Jeonbuk National UniversityJeonju Jeollabuk-do 54896Republic of Korea

The wide use of manganese dioxide(MnO_(2))as an electrode in all-solid-state asymmetric supercapacitors(ASCs)remains challenging because of its low electrical *** complication can be circumvented by introducing trivalent gadolinium(Gd)ions into the MnO_(2).Herein,we describe the successful hydrothermal synthesis of crystalline Gd-doped MnO_(2) nanorods with Ni(OH)_(2) nanosheets as cathode,which we combined with Fe_(3)O_(4)/GO nanospheres as anode for all-solid-state *** tests dem on strate that Gd dopi ng sign ifica ntly affected the electrochemical activities of the MnO_(2),which was further enhanced by introducing Ni(OH)_(2).The GdMnO_(2)/Ni(OH)_(2) electrode offers sufficient surface electrochemical activity and exhibits excellent specific capacity of 121.8 mA h g^(-1),at 1A g^(-1),appealing rate performance,and ultralong lifetime stability(99.3%retention after 10,000 discharge tests).Furthermore,the GdMnO_(2)/Ni(OH)_(2)//PVA/KOH//Fe_(3)O_(4)/GO solid-state ASC device offers an impressive specific energy density(60.25 W h kg^(-1))at a high power density(2332 W kg^(-1)).This investigation thus shows its large potential in developing novel approaches to energy storage devices.

关键词： Solid-state supercapacitor Manganese dioxide Gadolinium doping Nickel hydroxide nanosheets

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Facile synthesis of graphitic carbon-nitride supported antimony-doped tin oxide nanocomposite and its application for the adsorption of volatile organic compounds

引用

Journal of Environmental Sciences 2019年第5期31卷 35-42页

作者： Devi Prashad Ojha Jun Hee Song han joo Kim Department of Convergence Technology Engineering Chonbuk National University Eco-friendly Machine Parts Design Center Chonbuk National University

Antimony-doped tin oxide(ATO) nanoparticles with an average size of ～ 6 nm were prepared by co-precipitation and subsequent heat treatment. Graphitic carbon nitride(g-CN)/ATO hybrid nanocomposite was designed by the combination of thermally synthesized g-CN and ATO nanoparticles by ultrasonication. The materials were characterized using N2 adsorption/desorption(BET), X-ray diffraction(XRD), scanning electron microscopy(SEM), energy dispersive spectroscopy(EDS), transmission electron microscopy(TEM) and Fourier transform infrared spectroscopy(FTIR). A mixture of five volatile organic compounds(VOCs, chloroform, benzene, toluene, xylene and styrene) was used to compare the adsorption capacity of the samples. The adsorption capacity of ATO nanoparticles was improved by the addition of g-CN. Experimental data showed that, among the five VOCs,chloroform was the least adsorbed, regardless of the samples. The g-CN/ATO showed nearly three times greater adsorption capacity for the VOC mixture than pure ATO. The unchanged efficiency of VOC adsorption during cyclic use demonstrated the completely reversible adsorption and desorption behavior of the nanocomposite at room conditions. This economically and environmentally friendly material can be a practical solution for outdoor and indoor VOC removal.

关键词： Antimony-doped tin oxide(ATO) Graphitic carbon nitride(g-CN) Volatile organic compounds(VOC) Adsorption

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Selecting suitable sites for mountain ginseng(Panax ginseng)cultivation by using geographically weighted logistic regression

引用

Journal of Mountain Science 2017年第3期14卷 492-500页

作者： han Hee JANG Kwang-min CHUNG joo-sang Department of Forest Engineering Resources and ManagementCollege of ForestryOregon State UniversityCorvallisOR 97331USA Department of Forest Sciences College of Agriculture and Life SciencesSeoul National UniversitySeoul 08826Republic of Korea Research Institute for Agriculture and Life Sciences Seoul National UniversitySeoul 08826Republic of Korea

With the well-being trends to pursue a healthy life, mountain ginseng(Panax ginseng) is rising as one of the most profitable forest products in South Korea. This study was aimed at evaluating a new methodology for identifying suitable sites for mountain ginseng cultivation in the country. Forest vegetation data were collected from 46 sites and the spatial distribution of all sites was analyzed using GIS data for topographic position, landform, solar radiation, and topographic wetness. The physical and chemical properties of the soil samples, including moisture content, p H, organic matter, total nitrogen, exchangeable cations, available phosphorous, and soil texture, were analyzed. The cultivation suitability at each site was assessed based on the environmental conditions using logistic regression(LR) and geographically weighted logistic regression(GWLR) and the results of both methods were compared. The results show that the areas with northern aspect and higher levels of solar radiation, moisture content, total nitrogen, and sand ratio are more likely to be identified as suitable sites for ginseng cultivation. In contrast to the LR, the spatial modeling with the GWLR results in an increase in the model fitness and indicates that a significant portion of spatialautocorrelation in the data decreases. A higher value of the area under the receiver operating characteristic(ROC) curve presents a better prediction accuracy of site suitability by the GWLR. The geographically weighted coefficient estimates of the model are nonstationary, and reveal that different site suitability is associated with the geographical location of the forest stands. The GWLR increases the accuracy of selecting suitable sites by considering the geographical variations in the characteristics of the cultivation sites.

关键词： Panax ginseng Site suitability Logistic regression Geographically weighted logistic regression Geographic Information System South Korea

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Efficacy and safety of 0.4 percent sodium hyaluronate for endoscopic submucosal dissection of gastric neoplasms

引用

World Journal of Gastroenterology 2013年第20期19卷 3069-3076页

作者： Young Dae Kim Jun Lee Ju Yeon Cho seok Won Kim Seong Hwan Kim Young Kwan Cho Jin seok Jang Ji Sun han joo Young Cho Division of Gastroenterology and Hepatology Department of Internal MedicineMedical SchoolChosun UniversityGwangju 501-717South Korea Department of Internal Medicine Eulji HospitalEulji UniversitySeoul 139-872South Korea Department of Internal Medicine Dong A University College of MedicineBusan 602-715South Korea Department of Internal Medicine Institute for Digestive ResearchDigestive Disease CenterSoonchunhyang University College of MedicineSeoul 140-743South Korea

AIM:To evaluate the efficacy and safety of sodium hyaluronate solution(SH) in endoscopic submucosal dissection(ESD) of gastric ***:A prospective multicenter randomized,double blind,controlled trial was designed and utilized in this study.A total of 76 patients with 5-20 mm sized gastric neoplasms were enrolled at three academic hospitals in South Korea from June 2011 to October *** were randomly assigned to the 0.4% sodium hyaluronate or control *** lesions underwent endoscopic *** was performed with 0.4%SH and normal saline(NS) solution for submucosal *** was assessed using en bloc resection and the number of additional *** evaluation variables were the volume of injection material,steepness of mucosal elevation,bleeding rate,procedural time and operator ***,the safety was assessed by analyzing adverse events during the ***:The usefulness rate in the 0.4%SH group and the controlled group had statistically significant difference under intention to treat(ITT) analysis(90.91% vs 61.11% P = 0.0041).Under per protocol(PP),the usefulness rate is statistically significant different(93.10% vs 61.76%,P = 0.0036).The difference in volume of the solution injected between 0.4%SH group and the controlled group and NS group was also statistically significant under intention to treat and per protocol analysis(ITT:0.03 ± 0.02 mL vs 0.06 ± 0.03 mL,P = 0.0003,PP:0.03 ± 0.02 mL vs 0.06 ± 0.03 mL,P = 0.0004).Satisfaction above the grade good was significantly higher in the SH group under intention to treat and per protocol analysis(ITT:90.91% vs 61.11%,P = 0.0041,PP = 93.11% vs 61.77%,P = 0.0022).Adverse events above grade 3 were not noticed in either *** adverse events were treated and were judged as not associated with the submucosal injection ***:0.4%SH solution is a safe and effective agent that doesn't cause any significant adverse events and is useful for submucos

关键词： Sodium hyaluronate Endoscopic submucosal dissection Gastric neoplasm Endoscopic mucosal resection

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Human-Computer Interaction Lab(HCIL)in Seoul National University

引用

Visual Informatics 2020年第4期4卷 35-39页

作者： GuHyun han Jaemin Jo han joo Chae Jinwook Seo Department of Computer Science and Engineering Seoul National UniversityRepublic of Korea College of Computing Sungkyunkwan UniversityRepublic of Korea ROKIT Healthcare Republic of Korea

This article introduces Human–Computer Interaction Laboratory(HCIL)established at Seoul National University,Korea,in *** first summarized the history of foundation,achievement,and collaboration for the last 10 ***,we delineated our current research directions related to information ***,we presented our facilities and equipment to adequately support the research.

关键词： Lab introduction Information visualization Visual analytics Progressive visualization Machine learning for visualization MR and AR

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Direct dynamic-simulation approach to trajectory optimization

引用

Chinese Journal of Aeronautics 2021年第10期34卷 6-19页

作者： Sung Wook HUR Seong han LEE Yong Hyeon NAM Chang-joo KIM Department of Aerospace Information Engineering Konkuk UniversitySeoul 05029Republic of Korea

This paper proposes a new direct method for an efficient trajectory optimization using the point that the dynamics of a deterministic system are uniquely determined by initial states and controls imposed over the time horizon of *** effectively implement this concept,the Hermite spline is adopted to interpolate the continuous controls and the system dynamics are integrated with corresponding control parameters in *** a result,the optimal control problem can be transcribed into a nonlinear programming problem which has no dynamic equality constraints and no intermediate states in its design *** addition,the paper proposes an efficient recursive Jacobian estimation technique and introduces a Jacobian transformation matrix to straightforwardly handle the general state *** properties of the present method are thoroughly investigated through its applications to the trajectory optimization for a soft lunar landing from a parking orbit,including the detailed analyses for the de-orbiting *** computed results are compared with those using the pseudo-spectral method to demonstrate an extreme outperformance of the proposed method in the aerospace applications over the traditional direct method.

关键词： Trajectory optimization Direct method Hermite spline interpolation Pseudo-spectral integrator Soft lunar landing

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：