检索结果-南通市图书馆

Clinicopathological significance of altered Notch signaling in extrahepatic cholangiocarcinoma and gallbladder carcinoma

引用

World Journal of Gastroenterology 2011年第35期17卷 4023-4030页

作者： Hyun Ah Yoon Myung Hwan Noh Byung Geun Kim Ji Sun Han Jin seok Jang seok ryeol choi Jin Sook Jeong Jin Ho Chun Department of Gastroenterology Dong-A University Hospital3-1Dong dae shindongSeo-guBusan 602-715South Korea Department of Pathology Dong-A University Hospital3-1Dong dae shin-dongSeo-guBusan 602-715 South Korea Department of Preventive Medicine Inje University HospitalGae gum 2-dongBusanjinguBusan 614-735 South Korea

AIM:To investigate the role and clinicopathological significance of aberrant expression of Notch receptors and Delta-like ligand-4 (DLL4) in extrahepatic cholangiocarcinoma and gallbladder ***:One hundred and ten patients had surgically resected extrahepatic cholangiocarcinoma (CC) and gallbladder carcinoma specimens examined by immunohistochemistry of available paraffin *** was performed using anti-Notch receptors 1-4 and anti-DLL4 *** scored the immunopositivity of Notch receptors and DLL4 expression by percentage of positive tumor cells with cytoplasmic expression and intensity of *** nuclear localization was ***-logical parameters and survival data were compared with the expression of Notch receptors 1-4 and ***:Notch receptor proteins showed in the cytoplasm with or without nuclear expression in cancer cells,as well as showing weak cytoplasmic expression in non-neoplastic *** semiquantitative evaluation,positive immunostaining of Notch receptor 1 was detected in 96 cases (87.3%),Notch receptor 2 in 97 (88.2%),Notch receptor 3 in 97 (88.2%),Notch receptor 4 in 103 (93.6),and DLL4 in 84 (76.4%).In addition,coex- istent nuclear localization was noted [Notch receptor 1;18 cases (18.8%),Notch receptor 2;40 (41.2%),Notch receptor 3;32 (33.0%),Notch receptor 4;99 (96.1%),DLL4;48 (57.1%)].Notch receptor 1 expression was correlated with advanced tumor,node,metastasis (TNM) stage (P=0.043),Notch receptor 3 with advanced T stage (P=0.017),tendency to express in cases with nodal metastasis (P=0.065) and advanced TNM stage (P=0.052).DLL4 expression tended to be related to less histological differentiation (P=0.095).Coexistent nuclear localization of Notch receptor 3 was related to no nodal metastasis (P=0.027) and Notch receptor 4 with less histological differentiation (P=0.036),while DLL4 tended to be related inversely with T stage (P=0.053).Coexistent nuclear localizatio

关键词： Notch receptors Delta-like ligand-4 Cholangio-carcinoma Gallbladder carcinoma Immunohistochemistry

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Invariant operator theory for the single-photon energy in time-varying media

引用

Chinese Physics B 2010年第1期19卷 56-60页

作者： choi Jeong-ryeol School of Electrical Engineering and Computer Science Kyungpook National University

After the birth of quantum mechanics, the notion in physics that the frequency of light is the only factor that determines the energy of a single photon has played a fundamental role. However, under the assumption that the theory of Lewis-Riesenfeld invariants is applicable in quantum optics, it is shown in the present work that this widely accepted notion is valid only for light described by a time-independent Hamiltonian, i.e., for light in media satisfying the conditions, ε（t） = ε（0）, u（t） = u（0）, and σ（t） = 0 simultaneously. The use of the Lewis Riesenfeld invariant operator method in quantum optics leads to a marvelous result： the energy of a single photon propagating through time-varying linear media exhibits nontrivial time dependence without a change of frequency.

关键词： single-photon energy invariant operator theory time-varying media

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

An approach to dark energy problem through linear invariants

引用

Chinese Physics C 2011年第3期35卷 233-242页

作者： Jeong ryeol choi Department of Radiologic Technology Daegu Health College Division of Semiconductor and Display Engineering College of IT EngineeringKyungpook National University

The time evolution of vacuum energy density is investigated in the coherent states of inflationary universe using a linear invariant approach. The linear invariants we derived are represented in terms of annihilation operators. On account of the fact that the coherent state is an eigenstate of an annihilation operator, the wave function in the coherent state is easily evaluated by solving the eigenvalue equation of the linear invariants. The expectation value of the vacuum energy density is derived using this wave function. Fluctuations of the scalar field and its conjugate momentum are also investigated. Our theory based on the linear invariant shows that the vacuum energy density of the universe in a coherent state is decreased continuously with time due to nonconservative force acting on the coherent oscillations of the scalar field, which is provided by the expansion of the universe. In effect, our analysis reveals that the vacuum energy density decreases in proportion to t-β where β is 3/2 for radiation-dominated era and 2 for matter-dominated era. In the case where the duration term of radiation-dominated era is short enough to be negligible, the estimation of the relic vacuum energy density agrees well with the current observational data.

关键词： cosmological constant problem vacuum energy density coherent state linear invariant

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Quantum-classical correspondence for the inverted oscillator

引用

Chinese Physics C 2017年第11期41卷 56-62页

作者： Mustapha Maamache Jeong ryeol choi Laboratoire de Physique Quantique et Systèmes Dynamiques Faculté des SciencesUniversité Ferhat Abbas Sétif 1 Sétif 19000 Department of Radiologic Technology Daegu Health College

While quantum-classical correspondence for a system is a very fundamental problem in modern physics,the understanding of its mechanism is often elusive,so the methods used and the results of detailed theoretical analysis have been accompanied by active *** this study,the differences and similarities between quantum and classical behavior for an inverted oscillator have been analyzed based on the description of a complete generalized Airy function-type quantum wave *** inverted oscillator model plays an important role in several branches of cosmology and particle *** quantum wave packet of the system is composed of many sub-packets that are localized at different positions with regular intervals between *** is shown from illustrations of the probability density that,although the quantum trajectory of the wave propagation is somewhat different from the corresponding classical one,the difference becomes relatively small when the classical excitation is sufficiently *** have confirmed that a quantum wave packet moving along a positive or negative direction accelerates over time like a classical *** these main interpretations and others in the text,we conclude that our theory exquisitely illustrates quantum and classical correspondence for the system,which is a crucial concept in quantum mechanics.

关键词： quantum-classical correspondence inverted oscillator quantum wave packet

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Improved block matching approach to fast disparity estimation

引用

Journal of Systems Engineering and Electronics 2009年第6期20卷 1278-1285页

作者： Tao Tangfei Ja Choon Koo Hyouk ryeol choi School of Mechanical Engineering Xi'an Jiaotong Univ. Xi'an 710049 P. R. China State Key Lab. for Manufacturing Systems Engineering Xi'an 710049 P. R. China School of Mechanical Engineering Sungkyunkwan Univ. Suwon Republic of Korea

An improved block matching approach to fast disparity estimation in machine vision applications is proposed, where the matching criterion is the sum of the absolute difference（SAD）.By evaluating the lower bounds, which become increasingly tighter for the matching criteria, the method tries to successively terminate unnecessary computations of the matching criteria between the reference block in one image and the ineligible candidate blocks in another *** also eliminates the ineligible blocks as early as possible, while ensuring the optimal disparity of each ***, the proposed method can further speed up the elimination of ineligible candidate blocks by efficiently using the continuous constraint of disparity to predict the initial disparity of each *** performance of the new algorithm is evaluated by carrying out a theoretical analysis, and by comparing its performance with the disparity estimation method based on the standard block *** results demonstrate that the proposed algorithm achieves a computational cost reduction of over 50.5% in comparision with the standard block matching method.

关键词： machine vision block matching disparity estimation sum of the absolute difference.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Nonlinear description of Yang-Mills cosmology： cosmic inflation and the accompanying Hannay's angle

引用

Chinese Physics C 2017年第6期41卷 115-121页

作者： Yacine Bouguerra Mustapha Maamache Jeong ryeol choi Laboratoire de Physique Quantique et Systèmes Dynamiques Faculté des SciencesUniversite Ferhat Abbas Setif 1 Setif 19000 Algeria Département de Physique Facultédes Sciences Université de Jijel BP 98Ouled Aissa Jijel 18000 Algeria Department of Radiologic Technology Daegu Health College Yeongsong-ro 15 Buk-gu Daegu 41453 Republic of Korea

Hannay＇s angle is a classical analogue of the ＂geometrical phase factor＂ found by Berry in his research on the quantum adiabatic theorem. This classical analogue is defined if closed curves of constant action variables return to the same curves in phase space after an adaibatic evolution. Adiabatic evolution of Yang-Mills cosmology, which is described by a time-dependent quartic oscillator, is investigated. Phase properties of the Yang-Mills fields are analyzed and the corresponding Hannay＇s angle is derived from a rigorous evaluation. The obtained Hannay＇s angle shift is represented in terms of several observable parameters associated with such an angle shift. The time evolution of Hannay＇s angle in Yang-Mills cosmology is examined from an illustration plotted on the basis of numerical evaluation,and its physical nature is addressed. Hannay＇s angle, together with its quantum counterpart Berry＇s phase, plays a pivotal role in conceptual understanding of several cosmological problems and indeed can be used as a supplementary probe for cosmic inflation.

关键词： Yang-Mills cosmology Hannay angle time-dependent quartic Hamiltnian inflation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Testing the validity of the Ehrenfest theorem beyond simple static systems: Caldirola–Kanai oscillator driven by a time-dependent force

引用

Chinese Physics B 2016年第8期25卷 15-20页

作者： Salim Medjber Hacene Bekkar Salah Menouar Jeong ryeol choi Department of Material Science Faculty of Science University of M’sila Faculty of Technology University of Ferhat Abbas Setif 1 Laboratory of Optoelectronics and Compounds (LOC) Department of Physics Faculty of Science University of Ferhat Abbas Setif 1 Department of Radiologic Technology Daegu Health College

The relationship between quantum mechanics and classical mechanics is investigated by taking a Gaussian-type wave packet as a solution of the Schr o¨dinger equation for the Caldirola–Kanai oscillator driven by a sinusoidal force. For this time-dependent system, quantum properties are studied by using the invariant theory of Lewis and Riesenfeld. In particular,we analyze time behaviors of quantum expectation values of position and momentum variables and compare them to those of the counterpart classical ones. Based on this, we check whether the Ehrenfest theorem which was originally developed in static quantum systems can be extended to such time-varying systems without problems.

关键词： Ehrenfest theorem time-dependent Hamiltonian system invariant theory

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Quantum Systems Connected by a Time-Dependent Canonical Transformation

引用

Communications in Theoretical Physics 2009年第9期52卷 416-420页

作者： Kyu Hwang Yeon Jeong ryeol choi ZHANG Shou BK21 Physics Program and Department of Physics College of Natural Science Chungbuk National University Cheongju Chungbuk 361-763 Korea School of Electrical Engineering and Computer Science Kyungpook National University 1370 Sankyuk-dong Buk-gu Daegu 702-701 Korea Center for the Condensed-Matter Science and Technology Harbin Institute of Technology Harbin 150001 China Department of Physics College of Science Yanbinn University Yanji 133002 China

We study both classical and quantum relation between two Hamiltonian systems which are mutually connected by time-dependent canonical transformation. One is ordinary conservative system and the other is timedependent Hamiltonian system. The quantum unitary operator relevant to classical canonical transformation between the two systems are obtained through rigorous evaluation. With the aid of the unitary operator, we have derived quantum states of the time-dependent Hamiltonian system through transforming the quantum states of the conservative system. The invariant operators of the two systems are presented and the relation between them are addressed. We showed that there exist numerous Hamiltonians, which gives the same classical equation of motion. Though it is impossible to distinguish the systems described by these Hamiltonians within the realm of classical mechanics, they can be distinguishable quantum mechanically.

关键词： canonical transformation innumerable kind of Hamiltonians canonical quantization invariant operator unitary transformation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Intermittent, low-dose, antiandrogen monotherapy as an alternative therapeutic option for patients with positive surgical margins after radical prostatectomy

引用

Asian Journal of Andrology 2018年第3期20卷 270-275页

作者： Kyung Hwa choi Seung ryeol Lee Young Kwon Hong Dong Soo Park Department Urology CHA Bundang Medical Center CHA University Seongnam Korea.

The aim of the present study was to determine whether oncologic outcomes and adverse events associated with active on/off intermittent antiandrogen monotherapy （daily bicalutamide, 50 mg per day） are comparable with those of standard external beam radiation therapy （EBRT） or combined androgen blockade （CAB） therapy in prostate cancers with positive surgical margins after radical prostatectomy. Two hundred twenty-three patients with positive surgical margins post-radical prostatectomy who underwent active surveillance （AS, n = 32）, EBRT without hormone therapy （n = 55）, intermittent antiandrogen monotherapy without EBRT （IAAM, n= 50）, or CAB without EBRT （n = 86）, between 2007 and 2014, were reviewed retrospectively. Pathologic outcomes, biochemical recurrence rates, radiological disease progression, and adverse events were collected from medical records. Biochemical recurrence rates, biochemical recurrence-free survival rates, and radiological recurrence were not different between the groups （P = 0.225, 0.896, and 0.284, respectively）. Adverse event rates and severities were lower for IAAM compared with EBRT or CAB （both P 〈 0.05）, but were comparable to those for AS （P = 0.591 and 0.990, respectively）. Grade ：〉3 adverse events were not reported in the IAAM or AS groups. Erectile dysfunction and loss of libido rates were lower in the IAAM group compared with the EBRT and CAB groups （P = 0.032）. Gastrointestinal complications were more frequently reported in the EBRT group （P = 0.008）. Active on/off IAAM treatment might be an appropriate treatment option for patients with positive surgical margins after radical prostatectomy. Furthermore, regarding oncologic outcomes, IAAM was comparable to standard EBRT but had a milder adverse event profile.

关键词： androgen receptor antagonists disease progression margins of excision prostatectomy prostatic neoplasms

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Small bowel ulcer bleeding due to suspected clopidogrel use in a patient with clopidogrel resistance:A case report

引用

World Journal of Clinical Cases 2021年第15期9卷 3689-3695页

作者： Sang Hoon Lee Dong ryeol Ryu Sung Joon Lee Sung Chul Park Byung Ryul Cho Seung Koo Lee Sang Ji choi Hyun seok Cho Division of Gastroenterology Department of Internal MedicineKangwon National University HospitalKangwon National University School of MedicineChuncheon-si 24289South Korea Division of Cardiology Department of Internal MedicineKangwon National University HospitalKangwon National University School of MedicineChuncheon-si 24289South Korea Department of Anatomic Pathology Kangwon National University HospitalKangwon National University School of MedicineChuncheon-si 24289South Korea Department of Surgery Kangwon National University HospitalKangwon National University School of MedicineChuncheon-si 24289South Korea Department of Hospital Medicine Kangwon National University HospitalChuncheon-si 24289South Korea

BACKGROUND Clopidogrel is a platelet aggregation inhibitor used for the management of cardiovascular *** antiplatelet therapy decreases cardiovascular events after successful coronary drug-eluting stenting,it increases the risk of gastrointestinal(GI)*** 20%of the patients who take clopidogrel exhibit resistance to the *** SUMMARY We report the first case of a small bowel bleeding ulcer in an 86-year-old man with clopidogrel *** had a history of taking clopidogrel due to unstable *** was no evidence of bleeding in the stomach,duodenum,or colon through upper and lower GI *** abdominal computed tomography showed the extravasation of radiocontrast media at the *** of unstable vital signs,emergency surgery was *** ulcers with inflammation were found in the *** pathologic findings revealed simple *** VerifyNow P2Y12 test showed clopidogrel *** year after changing to aspirin,capsule endoscopy was performed and the small bowel ulcers were *** Small bowel ulcers and bleeding due to clopidogrel are not very common,but the prevalence is expected to increase in older age patients with risk factors despite clopidogrel resistance.

关键词： Clopidogrel Resistance Small bowel Multiple ulcers Hematochezia Surgery Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：