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Screening for colorectal cancer in Tianhe,Guangzhou:results of combining fecal immunochemical tests and risk factors for selecting patients requiring colonoscopy

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Gastroenterology Report 2018年第2期6卷 132-136,I0003页

作者： Yi liao senmao li Chunyu Chen Xuan He Feng lin Jianping Wang Zuli Yang Ping Lan Department of Gastrointestinal Surgery Sixth Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong 510655China Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Disease Sixth Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong 510655China Department of Colorectal Surgery Sixth Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong 510655China

Objective:To explore the performance of a protocol combining fecal immunochemical test(FIT)and a high-risk factor questionnaire(HRFQ)for selecting patients requiring colonoscopy as part of a population-based colorectal cancer(CRC)screening program in ***:From 2015 to 2016,we conducted a CRC screening program for all residents aged 45 years or older in Tianhe District,Guangzhou City,*** underwent an FIT and received an HRFQ as part of primary *** with positive FIT and/or HRFQ results were considered to be at high risk and were recommended to undergo ***:A total of 10074 subjects were recruited and enrolled in the screening *** the enrolled population,17.5%had positive FIT results and 19.4%had positive HRFQ *** those recommended to undergo diagnostic colonoscopy,773 did *** screening method’s overall positive predictive value(PPV)was 4.9%for non-adenomatous polyps,11.4%for low-risk adenomas(LRAs),15.9%for high-risk adenomas(HRAs)and 1.6%for *** PPVs of positive FIT results for nonadenomatous polyps,LRAs,HRAs and CRC were 5.2%,15.9%,22.5%and 2.5%,*** PPVs of positive HRFQ results for non-adenomatous polyps,LRA,HRA and CRC were 4.1%,10.2%,14.3%and 1.4%,*** PPVs associated with combined positive FIT and HRFQ results for non-adenomatous polyps,LRAs,HRAs and CRC were 4.5%,16.4%,23.7%and 2.8%,***:Our results suggest that this two-step CRC screening strategy,involving a combination of FIT and HRFQ followed by colonoscopy,is useful to identify early-stage *** high detection rates and PPVs for CRC and adenomas encourage this strategy’s use in ongoing screening programs.

关键词： colorectal cancer screening fecal immunochemical test high-risk factors colonoscopy positive predictive value

胃大弯侧外生性浆膜层下钙化性纤维性肿瘤1例

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消化肿瘤杂志（电子版） 2024年第3期16卷 385-388页

作者：朱常琰王修远胡玉秋陈广成李森茂金少文罗兴喜中山大学孙逸仙纪念医院胆胰外科广东广州510120 中山大学光华口腔医学院广东广州510080 中山大学附属第八医院(深圳福田)乳腺外科广东深圳518033 中山大学孙逸仙纪念医院消化内科广东广州510120 中山大学孙逸仙纪念医院胃肠外科广东广州510120

钙化性纤维性肿瘤(calcifying fibrous tumor,CFT)是一种以钙化、沙砾小体等为特征性表现的良性间充质病变,其主要成分为胶原化的纤维结缔组织。CFT可以发生于任何年龄,相对好发于女性,其发病部位有胸膜、胃肠道、纵隔、心脏、肺部、颈... 详细信息

钙化性纤维性肿瘤(calcifying fibrous tumor,CFT)是一种以钙化、沙砾小体等为特征性表现的良性间充质病变,其主要成分为胶原化的纤维结缔组织。CFT可以发生于任何年龄,相对好发于女性,其发病部位有胸膜、胃肠道、纵隔、心脏、肺部、颈部、背部、腹股沟、四肢等。其中发生于胃部的病例较少,以病例报道为主。目前对胃CFT的病因、临床表现、影像学特点以及治疗和预后的探索也并不深入。本例胃CFT的特殊性在于肿瘤发生在胃体大弯侧浆膜层下,并呈外生性发展,与胃壁间有蒂相连,早期可能不在胃囊内形成明显隆起,难以被常规胃镜检查检出,与目前报道较多的内生性CFT有明显区别。本病例报道能为具有类似临床表现的胃CFT患者的诊断方向及治疗方案提供一定的提示和指导。

关键词：钙化性纤维性肿瘤外生性浆膜层下胃

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重视结直肠癌的筛查和预防

中华消化外科杂志 2018年第2期17卷 121-126页

作者：兰平李森茂吴现瑞中山大学附属第六医院结直肠外科广州510655

我国结直肠癌发病率呈逐年上升趋势。结直肠癌具有发病隐匿、恶变时间长及早期肿瘤治愈率高的特性，这预示了开展筛查及预防工作对于降低结直肠癌发病率、提高治愈率、减少相关医疗成本有重大意义。国际上开展结直肠癌筛查及预防工作已... 详细信息

我国结直肠癌发病率呈逐年上升趋势。结直肠癌具有发病隐匿、恶变时间长及早期肿瘤治愈率高的特性，这预示了开展筛查及预防工作对于降低结直肠癌发病率、提高治愈率、减少相关医疗成本有重大意义。国际上开展结直肠癌筛查及预防工作已近半个世纪，而我国开展系统性筛查工作始于21世纪初。笔者重点探讨国内外结直肠癌筛查的成果、方法、策略及存在的主要问题。

关键词：结肠肿瘤直肠肿瘤预防筛查策略

Additives strategies to improving cycling stability of li metal batteries by modifying electrode electrolyte interphases

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Progress in Natural Science:Materials International 2024年第2期34卷 338-344页

作者： Yuan li Pengfei Huang Chunyu Cui Xiaoyuan Ma li Chen Zekun li linhai li Yuhong Tian School of Biological and Chemical Engineering Guangxi University of Science and Technology School of College of Chemistry and Chemical Engineering Hunan University Isky Future Energy Institute

li metal batteries（LMBs） have attracted much attention due to the ultra-high theoretical capacity of the li metal anode（LMA）.However,the uncontrollable dendrites growth and low coulombic efficiency hinder their practical ***,we explore 3,5-difluoropyridine（2F-BD） as a novel electrolyte additive to enable highperformance *** 2F-BD additive participates in and modifies the solvation structure of li ions by reducing the coordinated number of PF6-at the electrode surface,leading to the formation of a liF and li3N-rich solid electrolyte interphase（SEI）.The liF component increases the robustness of SEI and suppresses the formation of li dendrites,while the li3N component facilitates the transportation and reaction kinetics of li *** a result,the li‖li symmetric cell presents a stable cycling performance of up to 500 h at a current density of 1 mA *** coupling with liFePO4cathode,the obtained full cell achieves high specific capacities of 106.06 mA h g-1and 84.98 mA h g-1at 2.55 mA cm-2and 5.10 mA cm-2,respectively,and maintains a high capacity retention of84.0% after 1000 cycles at 0.13 mA cm-2,with an average cycling CE of 99.58%.

关键词： li metal batteries li dendrites Electrolyte additive

Leaching kinetics of fluorine during the aluminum removal from spent li-ion battery cathode materials

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Journal of Environmental Sciences 2024年第4期138卷 312-325页

作者： Shengjie li Jianxin Zhu Research Center for Eco-Environmental Sciences Chinese Academy of SciencesBeijing 100085China University of Chinese Academy of Sciences Beijing 100049China

The high content of aluminum(Al)impurity in the recycled cathode powder seriously affects the extraction efficiency of Nickel,Cobalt,Manganese,and lithium resources and the actual commercial value of recycled materials,so Al removal is crucially important to conform to the industrial standard of spent li-ion battery cathode *** this work,we systematically investigated the leaching process and optimum conditions associated with Al removal from the cathode powder materials collected in a wet cathode-powder peeling and recycling production line of spent li-ion batteries(liBs).Moreover,we specifically studied the leaching of fluorine(F)synergistically happened along with the removal process of Al,which was not concerned about in other studies,but one of the key factors affecting pollution prevention in the recovery *** mechanism of the whole process including the leaching of Al and F from the cathode powder was indicated by using NMR,FTIR,and XPS,and a defluoridation process was preliminarily investigated in this *** leaching kinetics of Al could be successfully described by the shrinking core model,controlled by the diffusion process and the activation energy was 11.14 kJ/***,the leaching of F was attributed to the dissolution of liPF6and decomposition of PVDF,and the kinetics associated was described by Avrami *** interaction of Al and F is advantageous to realize the defluoridation to some *** is expected that our investigation will provide theoretical support for the large-scale recycling of spent liBs.

关键词： Al removal F leaching Cathode powder Heating alkali leaching Leaching kinetics

Lateral tarsal strip procedure for involutional ectropion: A retrospective analysis of 85 cases and a comprehensive literature review

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Advances in Ophthalmology Practice and Research 2021年第1期1卷 9-14页

作者： Xiaoyi Hou Yongwei Guo senmao li Ming lin Renbing Jia Alexander Rokohl Ludwig M.Heindl Department of Ophthalmology West China Hospital of Sichuan UniversityChengduChina Department of Ophthalmology Faculty of Medicine and University Hospital CologneUniversity of Cologne:Universitat zu KolnGermany Eye Center Second Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhouChina Department of Ophthalmology Ninth People’s HospitalShanghai Jiao Tong UniversityShanghaiChina Center for Integrated Oncology(CIO)Aachen-Bonn-Cologne-Duesseldorf CologneGermany

Purpose:To evaluate the postoperative effect of the lateral tarsal strip(LTS)procedure in treating lower eyelid involutional ***:A retrospective study was performed on 85 eyelids in 67 patients with involutional ectropion who underwent LTS ***-and postoperative lower eyelid laxity and ocular symptoms as well as perioperative complications were *** back test was performed to evaluate the elasticity of lateral canthal tendon loosening and,a lower lid distraction test was performed to evaluate the degree of severity before *** surface diseases were evaluated by the Ocular Surface Disease Index(OSDI),and symptoms including conjunctivitis,corneal ulcer,dry eye syndrome,and ocular pain were *** patients were evaluated within one week and during the follow-up period of 4.28.3 ***,we reviewed the studies that also investigated the surgical effect of the LTS procedure in the literature from 1979 to ***:The success rate was 95%.Only four eyelids required a second surgical ***-three(86%)eyelids had an excellent position after surgery,9(11%)only little improvement,and three had no *** significant difference was found in the postoperative effects between different degrees of ectropion(p>0.05).No statistical correlation was found between surgical improvements and the ectropion severity(P>0.05).Fiftytwo out of 85 eyes had no discomfort after the *** complications included epiphora in 13 eyes(three cases caused by lacrimal punctum eversion),ocular pain in 12 eyes,wound hemorrhage in 12 eyes,and edema in 9 eyelids immediately after surgery,in which 91.2%(n=21)disappeared within one week and did not need any further ***:The lateral tarsal strip procedure can provide an aesthetically pleasing result for correcting the mild to moderate lower eyelid ectropion while maintaining decent eyelid function.

关键词： Involutional ectropion Aging eyelid Lateral tarsal strip Lower eyelid tension Post-operative surgical effects

SEI/dead li-turning capacity loss for high-performance anode-free solid-state lithium batteries

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Journal of Energy Chemistry 2024年第9期96卷 145-152页

作者： Qianwen Yin Tianyu li Hongzhang Zhang Guiming Zhong Xiaofei Yang Xianfeng li Division of Energy Storage Dalian National Laboratory for Clean EnergyDalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023LiaoningChina University of Chinese Academy of Sciences Beijing 100049China Key Laboratory of Long-Duration and Large-Scale Energy Storage Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023LiaoningChina Laboratory of Advanced Spectro-Electrochemistry and lithium-Ion Batteries Dalian National Laboratory for Clean EnergyDalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023LiaoningChina

Anode-free solid-state lithium metal batteries(AF-SSLBs)have the potential to deliver higher energy density and improved safety beyond lithium-metal ***,the unclear mechanism for the fast capacity decay in AF-SSLBs,either determined by dead li or solid electrolyte interface(SEI),limits the proposal of effective strategies to prolong cycling *** clarify the underlying mechanism,herein,the evolution of SEI and dead li is quantitatively analyzed by a solid-state nuclear magnetic resonance(ss-NMR)technology in a typical liPF6-based polymer *** results show that the initial capacity loss is attributed to the formation of SEI,while the dead li dominates the following capacity loss and the growth rate is 0.141 mA h cm^(−2)cycle−*** reduce the active li loss,the combination of inorganic-rich SEI and self-healing electrostatic shield effect is proposed to improve the reversibility of li deposition/dissolution behavior,which reduces the capacity loss rate for the initial SEI and following dead li generation by 2.3 and 20.1 folds,*** a result,the initial Coulombic efficiency(ICE)and stable CE increase by 15.1%and 15.3%in li-Cu cells,which guides the rational design of high-performance AF-SSLBs.

关键词： Solid-state lithium batteries Solid-state NMR Anode-free SEI Dead li

Theoretical Design of Defects as a Driving Force for Ion Transport in li_(3)OBr Solid Electrolyte

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Energy & Environmental Materials 2024年第3期7卷 143-153页

作者： Xingyun Luo Yanlu li Xian Zhao State Key Lab of Crystal Materials and Institute of Crystal Materials Shandong UniversityJinan 250100China Center for Optics Research and Engineering Shandong UniversityQingdao 266237China

Due to ever-increasing concerns about safety issues in using li ionic batteries,solid electrolytes have extensively *** li-rich antiperovskite li_(3)OBr has been considered as a promising solid electrolyte candidate,but it still suffers challenges to achieve a high ionic conductivity owing to the high intrinsic symmetry of the crystal ***,we presented a design strategy that introduces various point defects and grain boundaries to break the high lattice symmetry of li_(3)OBr crystal,and their effect and microscopic mechanism of promoting the migration of li-ion were explored *** has been found that li_(i)are the dominant defects responsible for the fast li-ion diffusion in bulk li_(3)OBr and its surface,but they are easily trapped by the grain boundaries,leading to the annihilating of the Frenkel defect pair V'_(li)+li_(i),and thus limits the V'_(li)diffusion at the grain *** V_(Br)defect near the grain boundaries can effectively drive V'_(li)across the grain boundary,thereby converting the carrier of li^(+)migration from li,in the bulk and surface to V'_(li)at the grain boundary,and thus improving the ionic conductivity in the whole li_(3)OBr *** work provides a comprehensive insight into the li^(+)transport and conduction mechanism in the li_(3)OBr *** opens a new way of improving the conductivity for all-solid-state li electrolyte material through the defect design.

关键词： defects density functional theory ionic migration solid electrolyte

Highly polar CoP/Co_(2)P heterojunction composite as efficient cathode electrocatalyst for li-air battery

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Chinese Chemical Letters 2024年第9期35卷 486-490页

作者： Miaomiao li Mengwei Yuan Xingzi Zheng Kunyu Han Genban Sun Fujun li Huifeng li Beijing Key Laboratory of Energy Conversion and Storage Materials College of ChemistryBeijing Normal UniversityBeijing 100875China Key Laboratory of Advanced Energy Materials Chemistry(Ministry of Education) College of ChemistryNankai UniversityTianjin 300071China Center for Advanced Materials Research Beijing Normal UniversityZhuhai 519087China

In order to advance the commercialization of rechargeable li-air batteries,it is of importance to explore cathode catalyst with efficient catalytic *** metal oxides have poor electrical conductivity,while cobalt phosphide has excellent electrical conductivity and large specific surface ***,its application in organic li-air batteries has been much less studied,and the electrocatalytic activity desires to be further ***,CoP/Co_(2)P heterojunction composite with higher polarity was *** discharge product of high-polarity CoP/Co_(2)P had a new porous box-like morphology,which was easy to be decomposed and exposed more active *** highly polar CoP/Co_(2)P heterostructure composite had homogeneous pores,the synergistic effect existed between CoP and Co_(2)P,and the discharge product was porous box mixed with li_(2)O_(2)and liOH,which made CoP/Co_(2)P achieve high specific capacity of14632 m Ah/g and cycle stably 161 times when used as air electrode cathode *** work furnished a thought for the construction of cathode catalysts with efficient catalytic activity for li-air batteries.

关键词： li-air battery Cathode catalyst CoP/Co_(2)P Heterojunction structure High polarity