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Novel per-oral cholangioscopy for treatment of occult accessory hepatic duct stones

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Gastroenterology Report 2023年第1期11卷 574-575页

作者： Tingting Yu Yaoting Li Hongfei He senlin hou Lichao Zhang Department of Biliopancreatic Endoscopic Surgery The Second Hospital of Hebei Medical UniversityShijiazhuangHebeiP.R.China

Introduction The accessory hepatic duct is a variation of the biliary tree and is considered to be an important factor contributing to bile duct injury during surgery[1].Accessory hepatic duct stones are a rare form of cholelithiasis.The angle at which the accessory hepatic duct opens into the common bile duct makes it difficult to remove stones using conventional endoscopic retrograde cholangiopancreatography(ERCP).We reported a rare and insidious case of an accessory hepatic duct stone.The patient’s abdominal computed tomography(CT)did not reveal any abnormalities,but endoscopic ultrasound revealed a stone in the bile duct opening into a branch of the common bile duct.The patient underwent ERCP,and cholangiography showed no abnormalities.However,the accessory hepatic duct opening was found in the common bile duct and the accessory hepatic duct stones were successfully removed using the EyeMax Choledochoscope System Digital Controller(Nanjing,China).

关键词： hepatic stones surgery

ERCP combined with colonoscopy in the treatment of biliary-colonic fistula:case report and literature review

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Gastroenterology Report 2023年第1期11卷 533-535页

作者： Hongfei He Tingting Yu Yaoting Li senlin hou Lichao Zhang Biliopancreatic Endoscopic Surgery Department The Second Hospital of Hebei Medical UniversityShijiazhuangHebeiP.R.China

Introduction Internal biliary fistula is a potentially serious complication of laparoscopic cholecystectomy[1].Biliary-colonic fistula is a rare type of internal biliary fistula.Formation of a biliary-colonic fistula can occur as the result of surgical injury,stone obstruction,and biliary hypertension.More infrequent causes include intestinal ulcer and malignant tumor.The formation of a fistula also has the effect of infection and inflammation.While very few cases of biliary-colonic fistulas have been reported,these cases typically present with the aforementioned clinical presentations[2,3].In the present case,a biliary-colonic fistula resulting from bile-duct injury after laparoscopic cholecystectomy was identified by endoscopic retrograde cholangiopancreatography(ERCP).We innovatively adopted ERCP combined with colonoscopy to clamp the sinus tract for the patient.

关键词： fistula biliary colonic

CNT modified by mesoporous carbon anchored by Ni nanoparticles for CO_(2) electrochemical reduction

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Carbon Energy 2022年第6期4卷 1274-1284页

作者： Juan Du Aibing Chen senlin hou Jing Guan College of Chemical and Pharmaceutical Engineering Hebei University of Science and TechnologyShijiazhuangHebeiChina The Second Hospital of Hebei Medical University ShijiazhuangHebeiChina School of Environmental and Municipal Engineering Qingdao University of TechnologyQingdaoShandongChina

The design of novel catalysts for efficient electroreduction of CO_(2) into valueadded chemicals is a promising approach to alleviate the energy crisis.Herein,we successfully modify the carbon nanotube by a layer of mesoporous carbon shell anchored by nickel(Ni)nanoparticles.Ni species effectively enable carbon deposition derived from pyrolysis of surfactant 1-hexadecyl trimethyl ammonium bromide to form a mesoporous carbon shell.At the same time,Ni nanoparticles can be embedded in the mesoporous carbon shell due to the confinement effect.Owing to the dispersive Ni nanoparticles and N-doping active sites of mesoporous carbon,the as-prepared electrocatalyst exhibits exciting catalytic performance for the selective reduction of CO_(2) to carbon monoxide(CO)with a maximum Faradaic efficiency of 98%at a moderate overpotential of−0.81 V(vs.reversible hydrogen electrode)and a high partial current density of 60 mA cm^(−2) in H-cell with an aqueous electrolyte.

关键词： carbon dioxide electrochemical reduction carbon monoxide CNT highly dispersed nickel nanoparticles

Synthesis of nitrogen-doped carbon spheres using the modified Stober method for supercapacitors

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Frontiers of Materials Science 2019年第2期13卷 156-164页

作者： Meng LIU Lei LIU Yifeng YU Haijun LV Aibing CHEN senlin hou College of Chemical and Pharmaceutical Engineering Hebei University of Science and Technology Shijiazhuang 050018 China The Second Hospital of Hebei Medical University Shijiazhuang 050000 China

Nitrogen-doped carbon spheres (NCSs) with uniform and regular morphology were facilely prepared by the modified Stober method. Hexamethylenetetramine (HMT) was selected as the starting material, which decomposed to provide nitrogen and carbon sources for the synthesis of NCSs. The decomposition product formaldehyde polymerized to form carbon skeleton with resorcinol after carbonization, and the in-situ nitrogen doping was achieved with the decomposed nitrogen source. NCSs were obtained with regular spherical morphology, high specific surface area, and suitable nitrogen doping. When used as the electrode material, NCSs exhibited good capacitance and electrochemical stability, indicating that NCSs be the promising candidate for the electrode material of high-performance supercapacitors.

关键词： carbon spheres nitrogen doping supercapacitor

Analysis of the relationship between bile duct and duodenal microbiota reveals that potential dysbacteriosis is the main cause of primary common bile duct stones

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Synthetic and Systems Biotechnology 2021年第4期6卷 414-428页

作者： Zhitang Lyu Tingting Yu Lichao Zhang Xiaona Xu Yijun Zhang Jihong Li Zhirong Li Wei Zhang senlin hou School of Life Sciences Institute of Life Science and Green DevelopmentHebei UniversityBaodingPR China The Second Hospital of Hebei Medical University ShijiazhuangPR China Key Laboratory of Microbial Diversity Research and Application of Hebei Province BaodingPR China Engineering Laboratory of Microbial Breeding and Preservation of Hebei Province BaodingPR China

Bacteria play an important role in the formation of primary Common Bile Duct(CBD)stones.However,the composition and function of the microbiota of bile duct in patients with primary CBD stones remained to be explored.We utilized the 16S rRNA gene high-throughput sequencing technology to analyze the microbial diversity and community composition of biliary and duodenal microbiota in 15 patients with primary CBD stones and 4 patients without biliary tract diseases.Alpha diversity analysis showed that the microbiota richness was similar in bile and intestinal fluid;Beta diversity analysis showed that there were differences in the composition between biliary microbiota and the duodenal microbiota,but the abundance of the main groups showed similarities.The composition of the biliary microbiota from gallstone patients was more complex,as was the duodenal microbiota.Proteobacteria and Firmicutes were the dominant bacteria at phylum level,accounting for at least 75%of the total reads in each subgroup.Pseudomonas and Escherichia􀀀Shigella were the major genus among subgroups,but Escherichia-Shigella had increased abundance in duodenal microbiota with primary choledocholithiasis,which may play an important role in stone formation.It is noteworthy that Clostridiumsensu_stricto,Lachnospiraceae_UCG-008,Butyrivibrio and Roseburia which could produce short chain fatty acids(SCFAs),were significantly decreased in biliary microbiota with primary CBD stones(p<0.05).Our study provided new insights into the compositional of normal biliary microbiota.The micro-ecology of biliary and duodenal in patients with stones is complex and closely related,and there is a potential for dysbacteriosis.The decrease in abundance of certain major acid-producing bacteria affects the health of the biliary tract and thus leads to the formation of stones.

关键词： Primary common bile duct stones ERCP Dysbacteriosis Bile duct microbiota Duodenal microbiota 16S rRNA gene high-throughput sequencing Short chain fatty acids

Safety of high-carbohydrate fluid diet 2 h versus overnight fasting before non-emergency endoscopic retrograde cholangiopancreatography: A single-blind, multicenter, randomized controlled trial

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中华医学杂志(英文版) 2024年第12期137卷 2023 Aug 24页

作者： Meng Wenbo Leung Joseph W. Wang Zhenyu Li Qiyong Zhang Leida Zhang Kai Wang Xuefeng Wang Meng Wang Qi Shao Yingmei Zhang Jijun Yue Ping Zhang Lei Zhu Kexiang Zhu Xiaoliang Zhang Hui hou senlin Cai Kailin Sun Hao Xue Ping Liu Wei Wang Haiping Zhang Li Ding Songming Yang Zhiqing Zhang Ming Weng Hao Wu Qingyuan Chen Bendong Jiang Tiemin Wang Yingkai Zhang Lichao Wu Ke Yang Xue Wen Zilong Liu Chun Miao Long Wang Zhengfeng Li Jiajia Yan Xiaowen Wang Fangzhao Zhang Lingen Bai Mingzhen Mi Ningning Zhang Xianzhuo Zhou Wence Yuan Jinqiu Suzuki Azumi Tanaka Kiyohito Liu Jiankang Nur Ula Weiderpass Elisabete Li Xun Department of Hepatobiliary Surgery The General Hospital of Ningxia Medical University Yinchuan Ningxia China Department of Hepatobiliary & Hydatid Digestive and Vascular Surgery Center Xinjiang Key Laboratory of Echinococcosis and Liver Surgery Research The First Affiliated Hospital of Xinjiang Medical University Urumqi Xinjiang China Department of Hepatobiliary and Pancreatic Surgery The First Hospital of Shanxi Medical University Taiyuan Shanxi China Department of General Surgery The Second Hospital of Lanzhou University Lanzhou Gansu China Department of Biliopancreatic Endoscopic Surgery The Second Hospital of Hebei Medical University Shijiazhuang Hebei China Gastrointestinal Surgery Department Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan Hubei China Department of Hepatobiliary Surgery The First Affiliated Hospital of Xi’an Jiaotong University Xi’an Shaanxi China Department of Hepatobiliary Surgery the Second Affiliated Hospital of Guangzhou Medical University Guangzhou Guangdong China Division of Biliopancreatic Surgery Department of General Surgery Second Xiangya Hospital Central South University Changsha Hunan China Department of General Surgery The First Hospital of Lanzhou University Lanzhou Gansu China The First Clinical Medical College of Lanzhou University Lanzhou Gansu China Clinical Research Centre Scientific Research Centre The Seventh Affiliated Hospital Sun Yat-sen University Shenzhen Guangdong China Department of Gastroenterology Hamamatsu Medical Center Hamamatsu Japan Department of Gastroenterology Kyoto Second Red Cross Hospital Kyoto Japan Cardiovascular Division Brigham and Women’s Hospital Harvard Medical School Boston MA USA Department of Public Health College of Health Sciences Qatar University Doha Qatar International Agency for Research on Cancer (IARC) Lyon France. Key Laboratory of Biological Therapy and Regenerative Medicine Transformation Gansu Province Lanzhou G

Background: Although overnight fasting is recommended prior to endoscopic retrograde cholangiopancreatography (ERCP), the benefits and safety of high-carbohydrate fluid diet (CFD) intake 2 h before ERCP remain unclear. This study aimed to analyze whether high-CFD intake 2 h before ERCP can be safe and accelerate patients’ recovery.Methods: This prospective, multicenter, randomized controlled trial involved 15 tertiary ERCP centers. A total of 1330 patients were randomized into CFD group (n = 665) and fasting group (n = 665). The CFD group received 400 mL of maltodextrin orally 2 h before ERCP, while the control group abstained from food/water overnight (>6 h) before ERCP. All ERCP procedures were performed using deep sedation with intravenous propofol. The investigators were blinded but not the patients. The primary outcomes included postoperative fatigue and abdominal pain score, and the secondary outcomes included complications and changes in metabolic indicators. The outcomes were analyzed according to a modified intention-to-treat principle.Results: The post-ERCP fatigue scores were significantly lower at 4 h (4.1 ± 2.6vs. 4.8 ± 2.8,t = 4.23,P <0.001) and 20 h (2.4 ± 2.1vs. 3.4 ± 2.4,t= 7.94,P <0.001) in the CFD group, with least-squares mean differences of 0.48 (95% confidence interval [CI]: 0.26–0.71,P <0.001) and 0.76 (95% CI: 0.57–0.95,P <0.001), respectively. The 4-h pain scores (2.1 ± 1.7vs. 2.2 ± 1.7,t = 2.60,P = 0.009, with a least-squares mean difference of 0.21 [95% CI: 0.05–0.37]) and positive urine ketone levels (7.7% [39/509]vs. 15.4% [82/533],χ2 = 15.13,P <0.001) were lower in the CFD group. The CFD group had significantly less cholangitis (2.1% [13/634]vs. 4.0% [26/658],χ2 = 3.99,P = 0.046) but not pancreatitis (5.5% [35/634]vs. 6.5% [43/658],χ2 = 0.59,P = 0.444). Subgroup analysis revealed that CFD reduced the incidence of complications in patients with native papilla (odds ratio [OR]: 0.61, 95% CI: 0.39–0.95,P = 0.028) in the multivariable models.Conclusion: Ingesting 400 mL of CFD 2 h before

关键词： Endoscopic retrograde cholangiopancreatography ERCP Carbohydrate Fasting Safety Complications Enhanced recovery after surgery Randomized controlled trial

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白鹭和大白鹭羽毛显微结构观察

南京林业大学学报（自然科学版） 2022年第1期46卷 156-162页

作者：侯森林费宜玲刘大伟张宁南京森林警察学院刑事科学技术学院野生动植物物证技术国家林业和草原局重点实验室江苏南京210023 国家林业和草原局森林公安司法鉴定中心江苏南京210023

【目的】探讨鸟类羽毛微观结构的差异,并据此鉴别鸟类。【方法】选取白鹭(Egretta garzetta)和大白鹭(E.alba)的飞羽、胸羽、尾羽及蓑羽4类羽毛作为研究对象,利用扫描电镜观察4类羽毛的羽小钩、腹齿及纤毛等微观结构的数量,利用SPSS 18.... 详细信息

【目的】探讨鸟类羽毛微观结构的差异,并据此鉴别鸟类。【方法】选取白鹭(Egretta garzetta)和大白鹭(E.alba)的飞羽、胸羽、尾羽及蓑羽4类羽毛作为研究对象,利用扫描电镜观察4类羽毛的羽小钩、腹齿及纤毛等微观结构的数量,利用SPSS 18.0对所观察的数据进行分析比较。【结果】飞羽中除腹齿数外,有钩羽小枝基柄长、羽小钩数、纤毛数以及无钩羽小枝基柄长在白鹭和大白鹭间均存在极显著差异;胸羽和尾羽有钩羽小枝的基柄长、腹齿数、羽小钩数、纤毛数以及无钩羽小枝的基柄长和腹齿数在白鹭和大白鹭间均存在显著或极显著差异;蓑羽纤毛数和基柄长在白鹭和大白鹭间存在极显著差异。【结论】除飞羽的腹齿外,所选的其他指标均可为白鹭和大白鹭的鉴别提供参考。

关键词：白鹭大白鹭羽毛显微结构

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常涉案龟鳖类动物形态特征拍摄浅析

江苏林业科技 2022年第5期49卷 43-48页

作者：侯森林李超野生动植物物证技术国家林业和草原局重点实验室江苏南京210023 南京森林警察学院刑事科学技术学院江苏南京210023 国家林业局森林公安司法鉴定中心江苏南京210023

在野生动物案件中,龟鳖类动物占有一定的比例,由于受办案成本等诸多因素的影响,办案机关将涉案动物拍成照片进行送检,但送检的照片往往不能满足鉴定要求。该研究对龟鳖类动物的主要识别特征进行归纳,分析龟鳖类动物拍摄前的准备工作和... 详细信息

在野生动物案件中,龟鳖类动物占有一定的比例,由于受办案成本等诸多因素的影响,办案机关将涉案动物拍成照片进行送检,但送检的照片往往不能满足鉴定要求。该研究对龟鳖类动物的主要识别特征进行归纳,分析龟鳖类动物拍摄前的准备工作和拍摄时的注意事项,总结不同龟鳖类动物形态鉴定照片的拍摄部位及拍摄要点,希望对公安和海关缉私等执法机关办理此类案件的取证工作有一定的借鉴作用,使涉案龟鳖类动物的鉴定更加准确、高效,更好地打击破坏野生动物资源的违法犯罪行为。

关键词：龟鳖类动物照片形态鉴定涉案拍摄

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10种隼形目鸟类尾羽羽小枝扫描电镜观察

南京林业大学学报（自然科学版） 2014年第4期38卷 163-167页

作者：侯森林南京森林警察学院江苏南京210023

选择10种隼形目鸟类尾羽,利用扫描电镜观察其显微结构,同时测量中央尾羽内、外翈宽度。结果表明:有钩羽小枝的羽小钩数,纤毛的粗细、长短、数量,腹齿数,无钩羽小枝的腹齿数以及羽小枝末端是否呈节状等特征在不同种类间存在差异。单因素... 详细信息

选择10种隼形目鸟类尾羽,利用扫描电镜观察其显微结构,同时测量中央尾羽内、外翈宽度。结果表明:有钩羽小枝的羽小钩数,纤毛的粗细、长短、数量,腹齿数,无钩羽小枝的腹齿数以及羽小枝末端是否呈节状等特征在不同种类间存在差异。单因素方差分析表明中央尾羽内、外翈宽度的比值在某些种类间存在差异,用于显微结构分析的3个指标在2个物种间至少有1个指标差异显著。

关键词：隼形目鸟类尾羽羽小枝显微结构物种鉴定