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Applying tuberculosis management time to measure the tuberculosis infectious pool at a local level in Ethiopia

Infectious Diseases of Poverty 2017年第1期6卷 1392-1400页

作者： senedu bekele gebreegziabher Gunnar Aksel Bjune Solomon Abebe Yimer Amhara Regional State Health Bureau Bahir DarEthiopia Department of Community Medicine Institute of Health and SocietyUniversity of OsloOsloNorway Oslo University Hospital OsloNorway Department of Bacteriology and Immunology Division of Infectious Disease ControlNorwegian Institute of Public HealthOsloNorway

Background:Measuring the size of the infectious pool of tuberculosis(TB)is essential to understand the burden and monitor trends of TB control program *** study applied the concept of TB management time to estimate and compare the size of the TB infectious pool between 2009 and 2014 in West Gojjam Zone of Amhara Region,***:New sputum smear-positive and smear-negative pulmonary TB(PTB)and retreatment cases who attended 30 randomly selected public health facilities in West Gojjam Zone from October 2013 to October 2014 were consecutively enrolled in the *** order to determine the infectious period,the TB management time(number of days from the onset of cough until start of anti-TB treatment)was computed for each patient *** number of undiagnosed TB cases was estimated and hence the TB management time for the undiagnosed category was *** total size of the TB infectious pool during the study period for the study zone was estimated as the annual number of infectious person ***:New smear-positive and smear-negative PTB cases contributed 25,050 and 12,931 infectious person days per year to the TB infectious pool,*** retreatment and presently undiagnosed cases contributed 8840 and 34,310 infectious person days per year,*** total size of the TB infectious pool in West Gojjam Zone during the study period was estimated at 81,131 infectious person days per year or 3405 infectious person days per 100,000 population per *** to a similar study done in 2009 in the study area,the current study showed reduction of the TB infectious pool by 244,279 infectious person ***:TB management time is a simple and practical tool that may help to estimate and compare the changes in the size of the TB infectious pool at local *** may also be used as an indicator to monitor the changes in TB control program performance.

关键词： Tuberculosis TB management time Infectious pool West Gojjam zone Ethiopia

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