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航空液压管路轴向挤压式接头组件连接强度的数值分析

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塑性工程学报 2024年第1期31卷 142-148页

作者：赵天章张铁森白雪山张帅韩颖杰戴群沈阳航空航天大学航空宇航学院辽宁沈阳110135 沈阳飞机工业(集团)有限公司辽宁沈阳110850

针对目前航空液压管接头无法满足高工作压力要求的问题,以Φ12 mm的钛合金轴向挤压式接头为研究对象,利用Abaqus平台建立了轴向挤压连接成形与拉脱试验过程的有限元模型,通过同参数条件下的拉脱试验验证了有限元模型的准确性。结果表明... 详细信息

针对目前航空液压管接头无法满足高工作压力要求的问题,以Φ12 mm的钛合金轴向挤压式接头为研究对象,利用Abaqus平台建立了轴向挤压连接成形与拉脱试验过程的有限元模型,通过同参数条件下的拉脱试验验证了有限元模型的准确性。结果表明,有限元模型计算误差仅为3.4%,接头组件连接强度是由导管与管套凹槽的轴向对抗阻力和导管与管套径向接触力共同决定的。系统研究了管套材料力学性能、凹槽结构、摩擦因数对接头组件连接强度的影响规律,管套材料屈服强度越高,连接强度越强;管套凹槽宽度每增长0.2 mm,连接强度提高约2.4%;摩擦因数每增加0.01,接头连接强度平均提升18%左右。

关键词：轴向挤压钛合金导管连接强度有限元

基于GJO特征量优选的AO-RF的变压器故障诊断模型

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高压电器 2024年第5期60卷 99-107页

作者：叶育林刘森黄松韩晓慧杜振斌李彬吕杰薛杨赵春琳中广核工程有限公司广东深圳518124 河北科技大学电气工程学院石家庄050018 保定天威保变电气股份有限公司河北省输变电装备电磁与结构性能重点实验室河北保定071056 保定天威新域科技发展有限公司河北保定071056 河北卫讯电力自动化设备有限公司河北衡水053000

在变压器故障诊断过程中,进行合理的特征优选,将有助于提高诊断模型的诊断精度,为此,文中提出了一种基于金豺优化算法(golden Jackal optimization,GJO)特征量优选与AO-RF的变压器故障诊断模型。首先,采用GJO对构建的21维变压器油中溶... 详细信息

在变压器故障诊断过程中,进行合理的特征优选,将有助于提高诊断模型的诊断精度,为此,文中提出了一种基于金豺优化算法(golden Jackal optimization,GJO)特征量优选与AO-RF的变压器故障诊断模型。首先,采用GJO对构建的21维变压器油中溶解气体特征量进行优选;然后,根据GJO得到的特征优选结果,采用天鹰算法(aquila optimizer,AO)优化随机森林(random forest,RF)的变压器故障诊断模型对变压器故障进行诊断,并与不同特征量、不同故障诊断模型的诊断结果进行了对比。实验结果表明:GJO优选特征量相比21维原始特征、三比值法、无编码比值法以及AO优选特征量的故障诊断准确率可提高1.12%~25.78%,kappa系数可提高0.02~0.24;AO-RF故障诊断模型较RF、SVM、ELM、SSA-RF、WOA-RF、GJO-RF模型的诊断准确率可提高1.84%~15.86%,kappa系数可提高0.02~0.16,验证了所提方法的有效性和准确性。

关键词：变压器故障诊断金豺算法随机森林天鹰算法

矿山机械用大型球铁齿圈的生产工艺研究及应用

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铸造设备与工艺 2024年第1期 9-11页

作者：王立春田学森常振共享装备股份有限公司宁夏银川750021

通过对大型球墨铸铁齿圈的两种生产工艺进行对比研究和数据分析,确定了先正火再粗加工的工艺流程,重点解决了正火后齿圈铸件的变形、硬度难以保证的问题,满足了客户的技术要求。后期通过批量生产验证,此工艺可实现大型球磨铸铁齿圈铸件... 详细信息

通过对大型球墨铸铁齿圈的两种生产工艺进行对比研究和数据分析,确定了先正火再粗加工的工艺流程,重点解决了正火后齿圈铸件的变形、硬度难以保证的问题,满足了客户的技术要求。后期通过批量生产验证,此工艺可实现大型球磨铸铁齿圈铸件批量稳定生产。

关键词：齿圈正火变形硬度

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玻璃瓶标签附着牢固度分析研究

绿色包装 2024年第2期 20-23页

作者：张威甘文森杜联学刁波叙永郎酒东方玻璃有限公司四川泸州646000 四川国检检测有限责任公司四川泸州646000 酒类包装安全性检测技术及应用重点实验室四川泸州646000

玻璃瓶是白酒包装中常用的容器,其标签附着牢固度对保证产品质量和消费者使用体验至关重要。本文介绍了一种白酒玻璃瓶标签附着牢固度测试方法,并对其原理、设备、操作流程及结果分析进行了详细阐述。实验结果表明,该方法能够有效地测... 详细信息

玻璃瓶是白酒包装中常用的容器,其标签附着牢固度对保证产品质量和消费者使用体验至关重要。本文介绍了一种白酒玻璃瓶标签附着牢固度测试方法,并对其原理、设备、操作流程及结果分析进行了详细阐述。实验结果表明,该方法能够有效地测试出白酒玻璃瓶标签的附着牢固度,为白酒生产企业提供了可靠的质量控制手段。

关键词：白酒业玻璃瓶标签牢固度

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透明细胞乳头状肾细胞肿瘤临床病理研究

临床与病理杂志 2024年第2期44卷 261-267页

作者：彭森孙辉王雪王朝夫吴迪徐州市中心医院病理科江苏徐州221000 上海交通大学医学院附属瑞金医院病理科上海200025

目的:透明细胞乳头状肾细胞肿瘤(clear cell papillary renal cell tumor,CCPRCT)是一种少见但重要的肾肿瘤类型,与其他肾细胞肿瘤具有类似的形态学特征,易导致误诊。本研究旨在探讨CCPRCT的临床病理特征、诊断及鉴别诊断要点,以提高其... 详细信息

目的:透明细胞乳头状肾细胞肿瘤(clear cell papillary renal cell tumor,CCPRCT)是一种少见但重要的肾肿瘤类型,与其他肾细胞肿瘤具有类似的形态学特征,易导致误诊。本研究旨在探讨CCPRCT的临床病理特征、诊断及鉴别诊断要点,以提高其病理诊断的准确性。方法:收集15例CCPRCT患者,观察其临床及影像学特点,分析其镜下形态、免疫表型,并复习相关文献。结果:15例患者中,男10例,女5例,年龄为(54±17)岁,10例患者肿瘤位于左肾,5例患者肿瘤位于右肾。组织学上肿瘤均由增厚的纤维囊包裹,并局限于肾实质内;肿瘤细胞排列成乳头状、管状、囊状、腺泡及实性等结构;乳头由小到中等大小、透明细胞质的单层细胞组成,肿瘤均为世界卫生组织/国际泌尿病理学会(World Health Organization/International Society of Urological Pathology,WHO/ISUP)1级或2级;细胞核反极性分布,即核上移,靠近腔面,远离基底,类似鲨鱼牙齿排列。免疫组织化学染色显示:细胞角蛋白7、碳酸酐酶9(carbonic anhydrase 9,CA9)和高分子量细胞角蛋白(34βE12)均为阳性表达;α甲基酰基辅酶A消旋酶、CD117、转录因子E3均为阴性表达;CCPRCT中典型的CA9表现方式是“U型”着色,即腔缘不表达,基底和侧面表达。患者术后随访均未见复发或转移。结论:CCPRCT是一种惰性肾细胞肿瘤,预后好,临床可能存在过诊断,其形态学为特征性的核朝向腔缘的线性排列,特殊的免疫表型CA9呈“U型”阳性,可以与其他肾细胞肿瘤区分开来,但仍然需要积累更多患者来阐释其预后。

关键词：透明细胞乳头状肾细胞肿瘤病理学特征诊断鉴别诊断

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基于改进MobileNet V3的矿物智能识别模型

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金属矿山 2024年第1期 174-181页

作者：宛鹤张金艳屈娟萍张崇辉薛季玮王森卜显忠西安建筑科技大学资源工程学院陕西西安710055 奥卢大学奥卢矿业学院芬兰奥卢FI-9004

针对当前矿物识别领域存在的精度不佳、适应性差、携带不便等问题,提出了一种基于改进MobileNet V3的矿物智能识别模型(CA-MobileNet V3)。为获得研究所需的有效数据集,通过由mindat. org网站和自行拍摄方式获取的矿物图像创建了一个包... 详细信息

针对当前矿物识别领域存在的精度不佳、适应性差、携带不便等问题,提出了一种基于改进MobileNet V3的矿物智能识别模型(CA-MobileNet V3)。为获得研究所需的有效数据集,通过由mindat. org网站和自行拍摄方式获取的矿物图像创建了一个包含19种矿物的数据集,对其进行数据增强处理,并按照8:1:1的比例划分为训练集、验证集和测试集。为提升模型对图像信息的特征提取能力,引入协调注意力机制,用以替代轻量型MobileNet V3模型的原始SE注意力机制,以提高矿物识别准确率。最后,采用迁移学习方法预训练CA-MobileNet V3模型,以加速模型收敛、提高泛化能力、避免过拟合。在训练过程中,将CA-MobileNet V3与mobilenet v3、MobileNet V3、ShuffleNet V2、Efficient Net V2等模型进行了性能比较。结果表明:各迁移模型均展现出显著的收敛速度优势,而CA-MobileNet V3矿物智能识别模型的Top1-准确率、Top2-准确率、f_1-score值分别达到93.90%、98.58%和93.89%,在所有模型中效果最佳,且模型大小仅为4.61 MB,属于轻量化模型。为验证模型有效性,t-SNE可视化分析被用于不同模型的识别效果比较,进一步印证了CA-MobileNet V3模型的优越性。

关键词：矿物分类迁移学习轻量化模型协调注意力机制 t-SNE

Characterization of acute-on-chronic liver diseases: A multicenter prospective cohort study

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World Journal of Hepatology 2024年第5期16卷 809-821页

作者： Yuan-Yao Zhang sen Luo Hai Li Shu-Ning Sun Xian-Bo Wang Xin Zheng Yan Huang Bei-Ling Li Yan-Hang Gao Zhi-Ping Qian Feng Liu Xiao-Bo Lu Jun-Ping Liu Hao-Tang Ren Yu-Bao Zheng Hua-Dong Yan Guo-Hong Deng Liang Qiao Yan Zhang Wen-Yi Gu Xiao-Mei Xiang Yi Zhou Yi-Xin Hou Qun Zhang Yan Xiong Cong-Cong Zou Jun Chen Ze-Bing Huang Xiu-Hua Jiang Ting-Ting Qi Yuan-Yuan Chen Na Gao Chun-Yan Liu Wei Yuan xue Mei Jing Li Tao Li Rong-Jiong Zheng Xin-Yi Zhou Jun Zhao Zhong-Ji Meng Department of Infectious Disease Institute of Biomedical ResearchRegulatory Mechanism and Targeted Therapy for Liver Cancer Shiyan Key LaboratoryHubei provincial Clinical Research Center for Precise Diagnosis and Treatment of Liver CancerTaihe HospitalHubei University of MedicineShiyan 442000Hubei ProvinceChina Department of Gastroenterology Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200120China Department of Infectious Diseases Southwest HospitalThe Third Military Medical University(Army Medical University)Chongqing 400000China Center of Integrative Medicine Beijing Ditan HospitalCapital Medical UniversityBeijing 100020China Department of Infectious Diseases Institute of Infection and ImmunologyUnion HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430020Hubei ProvinceChina Department of Infectious Diseases Hunan Key Laboratory of Viral HepatitisXiangya HospitalCentral South UniversityChangsha 110051Hunan ProvinceChina Hepatology Unit Department of Infectious DiseasesNanfang HospitalSouthern Medical UniversityGuangzhou 510515Guangdong ProvinceChina Department of Hepatology The First Hospital of Jilin UniversityChangchun 130021Jilin ProvinceChina Department of Liver Intensive Care Unit Shanghai Public Health Clinical CentreFudan UniversityShanghai 200093China Tianjin Institute of Hepatology Nankai University Second People's HospitalTianjin 300192China Infectious Disease Center The First Affiliated Hospital of Xinjiang Medical UniversityUrumqi 830054Xinjiang Uygur Autonomous RegionChina Department of Infectious Diseases and Hepatology The Second Hospital of Shandong UniversityJinan 250000Shandong ProvinceChina State Key Laboratory for Diagnosis and Treatment of Infectious Diseases Collaborative Innovation Center for Diagnosis and Treatment of Infectious DiseaseThe First Affiliated HospitalZhejiang University School of MedicineHangzhou 310000Zhejiang ProvinceChina Department of Infectious Diseases The Thir

BACKGROUND Acute-on-chronic liver disease(AoCLD)accounts for the majority of patients hospitalized in the Department of Hepatology or Infectious Diseases.AIM To explore the characterization of AoCLD to provide theoretical guidance for the accurate diagnosis and prognosis of AoCLD.METHODS Patients with AoCLD from the Chinese Acute-on-Chronic Liver Failure(ACLF)study cohort were included in this study.The clinical characteristics and outcomes,and the 90-d survival rate associated with each clinical type of AoCLD were analyzed,using the Kaplan-Meier method and the log-rank test.RESULTS A total of 3375 patients with AoCLD were enrolled,including 1679(49.7%)patients with liver cirrhosis acute decompensation(LC-AD),850(25.2%)patients with ACLF,577(17.1%)patients with chronic hepatitis acute exacer-bation(CHAE),and 269(8.0%)patients with liver cirrhosis active phase(LC-A).The most common cause of chronic liver disease(CLD)was HBV infection(71.4%).The most common precipitants of AoCLD was bacterial infection(22.8%).The 90-d mortality rates of each clinical subtype of AoCLD were 43.4%(232/535)for type-C ACLF,36.0%(36/100)for type-B ACLF,27.0%(58/215)for type-A ACLF,9.0%(151/1679)for LC-AD,3.0%(8/269)for LC-A,and 1.2%(7/577)for CHAE.CONCLUSION HBV infection is the main cause of CLD,and bacterial infection is the main precipitant of AoCLD.The most common clinical type of AoCLD is LC-AD.Early diagnosis and timely intervention are needed to reduce the mortality of patients with LC-AD or ACLF.

关键词： Acute-on-chronic liver disease Acute-on-chronic liver failure Liver cirrhosis Clinical features Prognosis

Improved formation density measurement using controllable D-D neutron source and its lithological correction for porosity prediction

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Nuclear Science and Techniques 2022年第1期33卷 24-34页

作者： Li Zhang Hua-Wei Yu Yang Li Wen-Bao Jia Xiao Han xue-sen Geng College of Resources Shandong University of Science and TechnologyTai’an 271019China School of Geosciences China University of PetroleumQingdao 266580China College of Mechanical and Electronic Engineering Shandong Agricultural UniversityTai’an 271018China Department of Nuclear Science and Engineering Nanjing University of Aeronautics and AstronauticsNanjing 211106China

Controllable D-D neutron sources have a long service life,low cost,and non-radioactivity.There are favorable prospects for its application in geophysical well logging,since traditional chemical radioactive sources used for well logging pose potential threats to the safety of the human body and environment.This paper presents an improved method to measure formation density that employs a D-D neutron source.In addition,the lithological effect on the measured density was removed to better estimate the formation porosity.First,we investigated the spatial distribution of capture gamma rays through Monte Carlo simulations as well as the relationship between the ratio of capture gamma ray counts and formation density to establish theoretical support for the design of density logging tools and their corresponding data processing methods.Second,we obtained the far to near detector counts of captured gamma rays for an optimized tool structure and then established its correlation with the density and porosity of three typical formations with pure quartz,calcite,and dolomite minerals.Third,we determined the values for correcting the densities of sandstone and dolomite with the same porosity using limestone data as the reference and established the equations for calculating the correction values,which lays a solid foundation for accurately calculating formation porosity.We observed that the capture gamma ray counts first increased then decreased and varied in different formations;this was especially observed in high-porosity formations.Under the same lithologic conditions(rock matrix),as the porosity increases,the peak value of gamma ray counts moves toward the neutron source.At different detector-source distances,the ratio of the capture gamma ray counts was well correlated with the formation density.An equation of the formation density conversion was established based on the ratio of capture gamma ray counts at the detector-source distances of 30 cm and 65 cm,and the calculated values were consistent with the true values.Af

关键词： Density measurement D-D neutron source Lithological correction Porosity prediction

FOXO1 Alleviates Liver Ischemia-reperfusion Injury by Regulating the Th17/Treg Ratio through the AKT/Stat3/FOXO1 Pathway

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Journal of Clinical and Translational Hepatology 2022年第6期10卷 1138-1147页

作者： Hao-Zhen Ren sen-Zhe Xia xue-Qian Qin An-Yin Hu Jing-Lin Wang Department of Hepatobiliary Surgery Affiliated Drum Tower Hospital of Nanjing University Medical SchoolNanjingJi-angsuChina Department of Hepatobiliary Surgery Nanjing Drum Tower Hospital Clinical College of Jiangsu UniversityNanjingJiangsuChina Department of Hepatobiliary Surgery Nanjing Drum Tower Hospital Clinical College of Traditional Chinese and Western MedicineNanjing University of Chinese MedicineNanjingJiangsuChina

Background and Aims:Hepatic ischemic reperfusion in-jury(IRI)occurring during surgery seriously affects patient prognosis.The specific mechanism of IRI has not been fully elucidated.The study aim was to explore the changes of in-flammatory environment,and the relationship of the Th17/Treg cell ratio and FOXO1 expression in hepatic IRI.Methods:Liver samples at different ischemic times were collected from patients and mice.The expression of inflammatory markers and FOXO1 in the liver was detected by western blotting and qPCR.Phenotypic changes of liver lymphocytes were analyzed by flow cytometry.The AKT/Stat3/FOXO1 pathway was veri-fied by targeting AKT with GSK2141795.The role of FOXO1 in liver inflammation and changes in lymphocyte phenotype was confirmed by upregulating FOXO1 with resveratrol.Re-sults:Prolonged ischemic time aggravates liver injury in both humans and mouse models of hepatic IRI.IR-stress caused Th17/Treg imbalance and FOXO1 down-regulation by activat-ing the AKT/Stat3/FOXO1 signaling pathway.Upregulation of FOXO1 reversed the Th17/Treg cytokine imbalance and altered the inflammation environment in the liver.Conclusions:Liver IRI induced Th17/Treg imbalance.Upregulation of FOXO1 re-versed the imbalance and alleviated liver inflammation.

关键词： Liver ischemia-reperfusion injury Inflammatory factors Th17 Treg AKT/Stat3/FOXO1 pathway