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Cost of Treatment of Chronic Spontaneous Urticaria in Turkey

Health 2016年第11期8卷 1098-1103页

作者： Mehtap Tatar Ayşen Şentürk Gülpembe Ergin oğuzhan Esin Tuna Cem Mat Emel Bülbül Başkan Ferda Artüz Mehmet Ali Gürer Nilgün Atakan Serhat İnalöz selin sezen çavuşoğlu Abdülkadir Keskinaslan İsmail Mete Şaylan Department of Health Care Management Faculty of Economics and Administrative Sciences Hacettepe University Ankara Turkey Polar Health Economics and Policy Consultancy Ankara Turkey Istanbul University Cerrahpasa Faculty of Medicine Istanbul Turkey Uludag University Faculty of Medicine Bursa Turkey Ankara Numune Training and Research Hospital Ankara Turkey Gazi University Faculty of Medicine Ankara Turkey Hacettepe University Faculty of Medicine Ankara Turkey Gaziantep University Faculty of Medicine Gaziantep Turkey Novartis Suryapi & Akel is Merkezi istanbul Turkey

Chronic Spontaneous Urticaria (CSU) is a chronic disease with significant negative impact on quality of life of patients. The direct and indirect costs of the disease can be substantial both for the health care system and society. The aim of this research is to estimate the cost of mild, moderate and severe CSU in Turkey and to forecast the cost of the disease from the payer (Social Security Institution—SSI) perspective. Expert opinions with Delphi technique were used in order to determine the cost items and their frequency. A questionnaire was designed to outline resources used in the out-patient, inpatient and emergency care episodes and was answered by dermatologists followed by a consensus meeting. Unit costs were calculated from the price list of the SSI. The annual total cost of treating the disease to the SSI was estimated as 262,111,978TL (94,417,870€) comprising 0.06% of the total healthcare budget in 2013. Since there is limited information about the cost of CSU in Turkey, the methodology and results of this study are unique and very important.

关键词： Chronic Idiopathic Urticaria Chronic Spontaneous Urticaria Turkey Cost

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Relationship between Exposure to Low Dose of x-ray and DNA Hypomethylation in Solid Tumors and Hematological Malignancies

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Biomedical and Environmental Sciences 2020年第7期33卷 528-537页

作者： YUKSEL selin DINNER Yildiz Department of Medical Biochemistry Cerrahpasa Medical FacultyIstanbul University-CerrahpasaIstanbulTurkey

X-rays are used in diagnostic and interventional radiology, and for treatment of certain benign and malignant diseases. Although these procedures utilize only low doses of radiation, the long term effects of exposure ... 详细信息

关键词： doses utilize malignant

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Inflationary effects of oil prices and domestic gasoline prices:Markov-switching-VAR analysis

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Petroleum Science 2015年第2期12卷 355-365页

作者： selin ozdemir Isil Akgul Department of Econometrics Faculty of EconomicsMarmara University

The purpose of this study is to contribute to the literature by studying the effects of sudden changes both on crude oil import price and domestic gasoline price on inflation for Turkey, an emerging country. Since an inflation targeting regime is being carried out by the Central Bank of Turkey, determination of such effects is becoming more important. Therefore empirical evidence in this paper will serve as guidance for those countries, which have an in- flation targeting regime. Analyses have been done in the period of october 2005-December 2012 by Markovswitching vector autoregressive （MS-VAR） models which are successful in capturing the nonlinear properties of variables. Using MS-VAR analysis, it is found that there are 2 regimes in the analysis period. Furthermore, regime changes can be dated and the turning points of economic cycles can be determined. In addition, it is found that the effect of the changes in crude oil and domestic gasoline prices on consumer prices and core inflation is not the same under different regimes. Moreover, the sudden increase in gasoline price is more important for consumer price infla- tion than crude oil price shocks. Another finding is the presence of a pass-through effect from oil price and ga- soline price to core inflation.

关键词： Crude oil price Domestic gasoline price Consumer price index - Core inflation MS-VAR model

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Production of naturally flavoured and carbonated beverages using Williopsis saturnus yeast and cold fermentation process

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Food Bioscience 2022年第4期48卷 207-215页

作者： Hasan Tanguler selin Sener Department of Food Engineering Nigde Omer Halisdemir UniversityNigdeTurkey

This study was carried out to develop a new functional fermented beverage that combines both the functional composition of grape(Tarsus beyazi)juice and metabolic products of the yeast Williopsis *** this reason,two trials were ***,the effect of different inoculation ratios and low fermentation temperatures at different times was *** naturally flavoured beverages,there was generally a decrease in total phenolic substance,antioxidant activity and total flavonoid amount with increasing fermentation time and inoculation *** panellists chose b-15d(1×10^(6)cells/mL *** yeast addition,15 days fermentation)and then c-15d(1×10^(7)cells/mL *** yeast addition,15 days fermentation)the most out of different beverages *** performed with yeasts inoculated at the rate of 1×10^(6)and 1×10^(7)cells/mL for 15 days was selected for the second trials based on both general and sensory *** this reason,these beverages,which were most preferred by the panellists,were re-manufactured and naturally flavoured carbonated beverages were produced by adding Co2 with the post-mix ***,sucrose,glucose and fructose values were determined in lower amounts in natural flavoured carbonated beverages compared to grape juice,which is given importance by *** in naturally flavoured beverages,carbonated beverages also decreased in total phenolic substance,antioxidant activity and total flavonoid amount with increasing fermentation *** addition,the c-15d natural flavoured carbonated beverage(1×10^(7)cells/mL *** yeast addition,15 days fermentation)was more favoured by the panellists than the commercially purchased carbonated *** results reported here are considered to be a good starting point for the development of new naturally flavoured and/or carbonated fermented beverages from the under-consumed grape.

关键词： Williopsis saturnus Tarsus beyazi Naturally flavoured beverage Carbonated beverage Cold fermentation Pseudo-second-order model

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Currency Undervaluation and Economic Rebalancing towards Services:Is China an Exception?

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China & World Economy 2013年第1期21卷 47-63页

作者： selin zyurt European Central Bank Frankfurt am Main

The present study investigates the main determinants of the employment share of the service sector using a panel of 66 countries over the period 1983-2007. Based on alternative measures of currency misalignment, the study extends the literature by investigating the impact of an undervalued currency on services. The empirical findings show that together with productivity and income per capita, currency undervaluation significantly determines the total employment share of services. Another key finding is that conventional cross- country determinants and the exchange rate undervaluation can only partially explain the underdevelopment of services activity in China and in other South-East Asian countries. In these countries, policies that aim at rebalancing the economy towards services should include elements to reform the domestic finaneial market, and the social security and health- care systems.

关键词： China currency misalignment employment share services

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Fertility variation in endemic populations of Ehrami black pine (Pinus nigra Arnold. subsp. pallasiana var. pyramidata)

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Journal of Forestry Research 2017年第4期28卷 683-686页

作者： Nebi Bilir Yilmaz Catal selin Tekocak Mahmut Cercioglu Forestry Faculty Suleyman Demirel University32260 IspartaTurkey Golhisar Vocational School Mehmet Akif University15400 BurdurTurkey

Fertility variation and effective number of parents were estimated in the 100 individuals from each of three plantation populations (P1, P2 and P3) of the endangered Pinus nigra. subsp. pallasiana var. pyramidata established in the Isparta-Golcuk district in southern Turkey in 1990. Potential relations between cone yield and growth characters (height, diameter at breast height, diameter at base and crown diameter) were also investigated. Large differences were found among populations and within populations for cone production and growth characters. Mean cone production was eight (ranging from 6.5 in P2 to 9.1 in P1) for the three populations. The 10 most productive individuals for cones produced 32% of the total cones in P1, 39% in P2 and 34% in P3; 21, 16 and 6 individuals, respectively did not produce any cones in the populations. According to the correlation analyses, the relation between cone yield and growth characters changed for the populations, while height, diameter at breast height and crown diameter were positively significantly correlated (r = 0.182, 0.135 and 0.209; p ≤ 0.05) with cone production for the three populations. Fertility variation was 1.81 in total of three populations, ranging from 1.72 in P3 to 3.45 in P1). Effective number of parents was 142 (55.2 of number of parents censused; 29%, P1; 49.8%, P2; 58.3%, P3).

关键词： Breeding Cone Effective number of parents Growth Pinaceae Reproductive

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Encapsulation of Moringa oleifera leaf extract in chitosan-coated alginate microbeads produced by ionic gelation

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Food Bioscience 2022年第6期50卷 1688-1695页

作者： Ebru Kurtulbaş Raneen Albarri Mehmet Torun selinŞahin Istanbul University – Cerrahpasa Faculty of EngineeringChemical Engineering Department34320AvcilarIstanbulTurkey Akdeniz University Faculty of EngineeringFood Engineering Department07058AntalyaTurkey

Encapsulation of potential bioactive natural substances is a promising preservation method for the natural additives over the synthetic antixodiants. In this study, ionic gelation has been used to encapsulate the Moringa oleifera leaf extract in biopolymers. Automatic solvent extraction was used to extract active material from the plant. Then, the active material was covered by chitosan/alginate via ionic gelation. Ionic gelation system was designed and optimized by Central Composite design of Response Surface Method (RSM). Exposure time to gelling medium (10–30 min), sodium alginate concentration (1%–2%, w/v) and chitosan concentration (0.5%–1%, w/v) were process parameters to be optimized for the maximum encapsulation efficiency concerning total phenolic content (EETPC ), rutin (major individual compound) concentration and inhibition effect of the capsules against DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate) free radical. Particle shape and morphology of the dried microcapsules show that the capsules obtained are quite spherical, uniform and have a regular structure depending on stereo-microscope and scanning electron microscopy (SEM) analyzes.

关键词： Hydrophilic compounds Ionotropic hydrogel Biopolymer Central composite design Particle size Particle morphology

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Gingival unit transfer using in the Miller Ⅲ recession defect treatment

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World Journal of Clinical Cases 2015年第2期3卷 199-203页

作者： selin Y?ld?r?m Bahar Kuru Department of Periodontology Dental FacultyMarmara University

The most significant factor for the success in soft tissue grafts is the synergistic relation between vascular configuration and involved tissues. In the soft tissue graft procedures, site specific donor tissue is assumed to have improved potential for function and aesthetic survive at recipient sites. on a clinical level, using site specific gingival unit graft that placed on traditionally prepared recipient site, results in predictable root coverage. In this case report the clinical effectiveness of gingival unit transfer(GUT) technique performed on Miller Ⅲ recession was presented and a similar recession case treated with free gingival graft(FGG) technique for comparison. Probing depth, recession depth, keratinized tissue width and clinical attachment level clinical parameters were measured at baseline and postoperative 8 mo. Percentage of defect coverage was evaluated at postoperative 8 mo. Creeping attachment was assessed at postoperative 1, 3, 6 and 8 mo. The GUT revealed better defect coverage and creeping attachment results than the FGG in the treatment of Miller Ⅲ defects.

关键词： Autografting Gingiva Gingival recession Tooth root Transplants

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Severe aortic stenosis and acute coronary syndrome in an elderly patient with idiopathic thrombocytopenic purpura:a therapeutic challenge

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Journal of Geriatric Cardiology 2022年第3期19卷 241-244页

作者： Mehmet Rasih Sonsoz selin Berk Hamdi Pusuroglu Ahmet Guler Fatih Uzun Department of Cardiology Basaksehir Cam&Sakura City HospitalIstanbulTurkey Department of Hematology Basaksehir Cam&Sakura City HospitalIstanbulTurkey

Severe valvular aortic stenosis is a commonly encountered disorder in the elderly,and the intervention is indicated when the pa-tient is *** aortic valve im-plantation(TAVI)is a safer therapeutic option in symptomatic patients who cannot undergo surgery or who have high,intermediate,or even low surgic-al risk.[1]Idiopathic thrombocytopenic purpura(ITP)is acquired thrombocytopenia caused by autoan-tibodies against platelet antigens.[2]Herein,we re-port an 81-year-old patient,who was diagnosed with primary ITP two years ago,was admitted to the hospital for heart failure with acute coronary syndrome and severe aortic *** describe our experience in the peri-operative management of the case of coronary and structural intervention in a patient with ITP.

关键词： coronary aortic patient

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Performance of RC buildings after Kahramanmaraş Earthquakes: lessons toward performance based design

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Earthquake Engineering and Engineering Vibration 2023年第4期22卷 883-894页

作者： Baris Binici Ahmet Yakut Koray Kadas ozan Demirel Ugur Akpinar Afsin Canbolat Firat Yurtseven orkun oztaskin selin Aktas Erdem Canbay Department of Civil Engineering Middle East Technical UniversityAnkaraTurkey

Two simultaneous earthquakes occurred in the Kahramanmaraş-Pazarcık and Kahramanmaraş-Elbistan districts of Turkey on February 6,2023,and with magnitudes of 7.7 and 7.6,*** events caused the highest estimated loss recorded in Turkey within the last century from natural *** key reason for the extensive loss was the proximity of eleven cities to the earthquake *** East Technical University teams investigated the building sites in Gaziantep,Kahramanmaras,Hatay,Adiyaman and *** ground motion recordings revealed that in certain locations of Gaziantep,Kahramanmaraşand Hatay,the ground motion levels exceeded the maximum credible earthquake level defined for a return period of 2,475 years in the Turkish Earthquake *** building performance was investigated with respect to the construction year,which is a good indicator of compliance with modern seismic codes and inspection *** 97%of the collapsed buildings were constructed prior to 2000,whereas over 5,000 buildings,which were built after 2000,collapsed or required urgent *** of the buildings with minor or greater structural damage sustained heavy infill wall damage rendering occupancy *** from damage in older construction with significant structural deficiencies,the damage in some of the more recent and better constructed buildings was observed to be surprisingly *** can be attributed to the level of ground motion,significant ductility demands,poor material and workmanship and damage to non-structural *** the estimated total loss of above 100 billion dollars and over 50,000 casualties,the current seismic design criterion based on ductility and acceptance of structural damage should be re-evaluated to ensure a more resilient urban environment in high seismic regions.

关键词： earthquake damage Kahramanmaras earthquake RC Building seismic codes poor performance

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