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Technology and Inequity in Health： The Geographical Distribution of Glucometers for the Control of Diabetes

Journal of Mathematics and System Science 2015年第12期5卷 523-536页

作者： Jane Mary Guimaraes erika Santos de Aragao Gervasio Ferreira Santos Bethania de Araujo Almeida Danielsilva A. de Carvalho sebastinio antonio loureiro de souza e silva Institute of Humanities Arts and Sciences Federal University of Southern Bahia Brazil. Institute of Collective Health Federal University of Bahia Brazil. Faculty of economic Sciences Federal University of Bahia Brazil. Gonzalo Moniz Research Centre Salvador Bahia Brazil.

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Recycling process and proto-kimberlite melt metasomatism in the lithosphere-asthenosphere boundary beneath the Amazonian Craton recorded by garnet xenocrysts and mantle xenoliths from the Carolina kimberlite

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Geoscience Frontiers 2022年第5期13卷 89-105页

作者： Fernanda Gervasoni Tiago Jalowitzki Marcelo Peres Rocha Ricardo Kalikowski Weska eduardo Novais-Rodrigues Rodrigo antonio de Freitas Rodrigues Yannick Bussweiler elisa Soares Rocha Barbosa Jasper Berndt elton Luiz Dantas Valmir da silva souza Stephan Klemme Centro de engenharias Universidade Federal de Pelotas(UFPel)PelotasBrazil Programa de Pós-graduação em Geociências Universidade Federal do Rio Grande do SulPorto AlegreBrazil Programa de Pós-graduação em Geologia Instituto de GeociênciasUniversidade de Brasília(UnB)BrasíliaBrazil Faculdade de Geociências Universidade Federal do Mato Grosso(UFMT)CuiabáBrazil Institut für Geologie und Mineralogie Universität zu KölnGermany Faculdade de Ciências e Tecnologia Universidade Federal de Goiás(UFG)Aparecida de GoiâniaBrazil Institut für Mineralogie Universität MünsterMünsterGermany

Here we present new data on the major and trace element compositions of silicate and oxide minerals from mantle xenoliths brought to the surface by the Carolina kimberlite,Pimenta Bueno Kimberlitic Field,which is located on the southwestern border of the Amazonian *** also present Sr-Nd isotopic data of garnet xenocrysts and whole-rocks from the Carolina *** xenoliths are mainly clinopyroxenites and *** of the clinopyroxenites were classified as GPP–PP–PKP(garnet-phlogopite peridotite,phlogopite-peridotite,phlogopite-K-richterite peridotite)suites,and two clinopyroxenites(eclogites)and two garnetites are relicts of an ancient subducted *** and pressure estimates yield 855–1102℃ and 3.6–7.0 GPa,*** are enriched in light rare earth elements(LRee)(La_(N)/Yb_(N)=5–62;Ce_(N)/Sm_(N)=1–3;where N=primitive mantle normalized values),they have high Ca/Al ratios(10–410),low to medium Ti/eu ratios(742–2840),and low Zr/Hf ratios(13–26),which suggest they were formed by metasomatic reactions with CO_(2)-rich silicate *** with high TiO_(2)(>2.0 wt.%),Al_(2)O_(3)(>12.0 wt.%),and FeOt(5.0–13.0 wt.%)resemble those found in the groundmass of kimberlites,lamproites and ***,phlogopite with low TiO_(2)(er Al_(2)O_(3)(e similar to those present in GPP-PP-PKP,and in MARID(mica-amphibole-rutile-ilmenite-diopside)and PIC(phlogopite-ilmenite-clinopyorxene)*** GPP-PP-PKP suite of xenoliths,together with the clinopyroxene and phlogopite major and trace element signatures suggests that an intense proto-kimberlite melt metasomatism occurred in the deep cratonic lithosphere beneath the Amazonian *** Sr-Nd isotopic ratios of pyrope xenocrysts(G3,G9 and G11)from the Carolina kimberlite are characterized by high ^(143)Nd/^(144)Nd(0.51287–0.51371)and eNd(+4.55 to+20.85)accompanied with enriched ^(87)Sr/^(86)Sr(0.70405–0.71098).These results suggest intera

关键词： Carolina kimberlite K-rich mantle xenoliths Ancient subducted slab Proto-kimberlite melt metasomatism

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Unraveling one billion years of geological evolution of the southeastern Amazonia Craton from detrital zircon analyses

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Geoscience Frontiers 2022年第5期13卷 129-152页

作者： Camille Rossignol Paul Yves Jean antonio Francesco Narduzzi eric Siciliano Rego Lívia Teixeira Romário Almeida de souza Janaína N.Ávila Marco A.L.silva Cristiano Lana Ricardo I.F.Trindade Pascal Philippot departamento de Geofísica Instituto de AstronomiaGeofísica e Ciências Atmosféricas da Universidade de São PauloRua do Matão1226-Cidade UniversitáriaSão Paulo 05508-090Brazil Institut de Physique du Globe de Paris Universitéde ParisCNRSParisFrance Géosciences Montpellier Universitéde MontpellierCNRSUniversitédes AntillesMontpellierFrance Instituto de Geociências Universidade de São PauloRua do Lago562-Cidade UniversitáriaSão Paulo 05508-080Brazil Instituto de Geociências e engenharias Universidade Federal do Sul e Sudeste do Pará–UNIFESSPAFolha 17Quadra 04Lote especialNova MarabáMarabáPará68505-080Brazil Research School of earth Sciences The Australian National University142 Mills RoadCanberraACT 2601Australia Applied Isotope Research Group Departamento de GeologiaEscola de MinasUniversidade Federal de Ouro PretoRua Diogo de Vasconcelos12235400-000 Ouro PretoMGBrazil

despite representing one of the largest cratons on earth,the early geological evolution of the Amazonia Craton remains poorly known due to relatively poor exposure and because younger metamorphic and tectonic events have obscured initial *** this study,we investigated the sedimentary archives of the Carajás Basin to unravel the early geological evolution of the southeastern Amazonia *** Carajás Basin contains sedimentary rocks that were deposited throughout a long period spanning more than one billion years from the Mesoarchean to the *** oldest archives preserved in this basin consist of a few ca.3.6 Ga detrital zircon grains showing that the geological roots of the Amazonia Craton were already formed by the *** the Paleoarchean or the early Mesoarchean(e Carajás Basin was large and rigid enough to sustain the formation and preservation of the Rio Novo Group greenstone ***,during the Neoarchean,at ca.2.7 Ga,the southeastern Amazonia Craton witnessed the emplacement of the Parauapebas Large Igneous Province(LIP)that probably covered a large part of the craton and was associated with the deposition of some of the world largest iron *** emplacement of this LIP immediately preceded a period of continental extension that formed a rift infilled first by iron formations followed by terrigenous *** major change of sedimentary regime might have been controlled by the regional tectonic evolution of the Amazonia Craton and its emergence above *** the Paleoproterozoic,at ca.2.1 Ga,the Rio Fresco Group,consisting of terrigenous sediments from the interior of the Amazonia Craton,was deposited in the Carajás *** that time,the Amazonian lithosphere could have either underwent thermal subsidence forming a large intracratonic basin or could have been deformed by long wavelength flexures that induced the formation of basins and swells throughout the craton under the influence of

关键词： Carajás Basin Chemical Abrasion–LA-ICP-MS analyses Age distribution comparison Parauapebas Large Igneous Province Transamazonian orogeny

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euborellia annulipes Mortality and Predation on Diatraea saccharalis eggs after Application of Chemical and Biological Insecticides

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Agricultural Sciences 2023年第1期14卷 11-22页

作者： Rodrigo Marin Arroyo Joice Mendonça de souza Gilmar Da silva Nunes Dagmara Gomes Ramalho Sergio antonio de Bortoli UNeSP S&#227 o Paulo State University Jaboticabal SP Brazil Manserv Porto Nacional Tocantins Brazil

Chemical and biological insecticides have been frequently used in sugarcane fields to control insects-pests, including the sugarcane borer, Diatraea saccharalis. Among the products used, those based on chlorantraniliprole and Metarhizium anisopliae entomopathogenic fungus, stand out. euborellia annulipes is an insect of the order dermaptera considered a potential predator of sugarcane borer eggs. This study aimed to evaluate the direct and indirect effects of the bioinsecticide based on M. anisopliae (Metarril®) and the chemical insecticide chlorantraniliprole (Altacor®) on the mortality of e. annulipes nymphs and adults, the predation and feeding preference of earwigs in eggs treated with the formulated products. Predator mortality was evaluated for seven days after treatment, while the effect on predation was analyzed by preference tests with and without choice, using prey eggs. The products tested were selective to the predator, causing ≤ 2% mortality and not affecting predation. The application of M. anisopliae on sugarcane borer eggs favored the food preference of fourth-instar nymphs, males, and females of the predator. Our results show that Metarril® and Altacor® can be used to control D. saccharalis when associated with the predator e. annulipes.

关键词： Sugarcane Borer Biological Control Food Preference earwigs

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Serum 1,3-beta-D-glucan as a noninvasive test to predict histologic activity in patients with inflammatory bowel disease

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World Journal of Gastroenterology 2021年第9期27卷 866-885页

作者： Katia Farias e silva Hayandra F Nanini Cynthia Machado Cascabulho Siane L B Rosas Patricia T Santana antonio Joséde V Carneiro elias Anaissie Marcio Nucci Heitor Siffert Pereira de souza department of Clinical Medicine School of MedicineFederal University of Rio de JaneiroRio de Janeiro 21941-913Brazil Laboratory of Innovations in Therapies Education and BioproductsInstituto Oswaldo CruzRio de Janeiro 21040-360Brazil Clinical Trial and Consulting Services CincinnatiOH 45267United States Internal Medicine D'Or Institute for Research and Education(IDOR)Rio de Janeiro 22281-100Brazil

BACKGROUND 1,3-beta-D-glucan(BG)is a ubiquitous cell wall component of gut *** hypothesized that the serum levels of BG could reflect active intestinal inflammation in patients with inflammatory bowel *** To determine whether the serum BG concentrations correlate with intestinal *** A prospective observational study was performed in a tertiary referral center,from 2016 to 2019,in which serum BG was determined in 115 patients with Crohn’s disease(CD),51 with ulcerative colitis(UC),and 82 controls using a photometric detection *** activity was determined by ileocolonoscopy,histopathology,magnetic resonance enterography,and biomarkers,including fecal calprotectin(FC),C-reactive protein,and a panel of *** ability of BG to detect active vs inactive disease was assessed using the area under the receiver operating characteristic *** subgroup analysis,serial BG was used to assess the response to therapeutic *** The serum BG levels were higher in CD patients than in controls(P=0.0001).The BG levels paralleled the endoscopic activity in CD patients and histologic activity and combined endoscopic and histologic activity in both CD and UC *** area under the curve(AUC)in receiver operating characteristic analysis to predict endoscopic activity was 0.694[95%confidence interval(CI):0.60-0.79;P=0.001]in CD,and 0.662(95%CI:0.51-0.81;P=0.066)in UC *** AUC in receiver operating characteristic analysis to predict histologic activity was 0.860(95%CI:0.77-0.95;Pes of BG for both endoscopic and histologic activity were 60μg/mL in CD,and 40μg/mL in UC *** analysis showed that the results based on BG of 40 and 60μg/mL were more specific for predicting endoscopic activity(71.8%and 87.2%for CD;and 87.5%and 87.5%for UC,respectively)than FC(53.3%and 66.7%for CD;and 20%and 80%for UC,respectively);and

关键词： Crohn’s disease Ulcerative colitis Inflammatory bowel disease Beta-glucan Histologic activity Noninvasive test

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evaluation of physicochemical properties as supporting information on quality control of raw materials and veterinary pharmaceutical formulations

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Journal of Pharmaceutical Analysis 2018年第3期8卷 168-175页

作者： Sara da silva Anacleto Marcella Matos Cordeiro Borges Hanna Leijoto de Oliveira Andressa Reis Vicente eduardo Costa de Figueiredo Marcone Augusto Leal de Oliveira Barbara Juliana Pinheiro Borges Marcelo antonio de Oliveira Warley de souza Borges Keyller Bastos Borges departamento de Ciencias Naturals Universidade Federal de Sao Joao del-Rei Campus Dom Bosco Praca Dora Helvecio 74 Fabricas 36301-160 Sao Joao del-Rei Minas Gerais Brazil departamento de Quimica Universidade Federal do Espirito Santo Avenida Fernando Ferrari 514 Goiabeiras 29075-910 Vitdria Espirito Santo Brazil Laboratorio de Analise de Toxicantes e Farmacos Faculdade de Ciencias Farmaceuticas Universidade Federal de Alfenas Rua Gabriel Monteiro da Silva 700 Centro 37130-000 Alfenas Minas Gerais Brazil departamento de Quimica Universidade Federal de Juiz de Fora Rua Jose Lourenco Kelmer s/n 36036-330 Juiz de Fora Minas Gerais Brazil Centro de Ciencias da Saude Universidade Federal do Espirito Santo Avenida Marechal Campos 1468 Maruipe 29.043-900 Vitori Espirito Santo Brazil Centro Universitario Norte do espirito Santo Universidade Federal do Espirito Santo Br 101 Norte Km 67 Sao Mateus Espirito Santo Brazil

This study aimed to show that the physicochemical proprieties obtained by Fourier transform infrared spectroscopy （FTIR）, thermogravimetry （TG）, and scanning electronic microscopy （SeM） can be useful tools for evaluating the quality of active pharmaceutical ingredients （APIs） and pharmaceutical products. In addition, a simple, sensitive, and efficient method employing HPLC-DAD was developed for simulta- neous determination of lidocaine （LID）, ciprofloxacin （CFX） and enrofloxacin （eFX） in raw materials and in veterinary pharmaceutical formulations. Compounds were separated using a Gemini Cm （250 mm×4.6 mm, 5μm） Phenomenex column, at a temperature of 25℃, with a mobile phase containing 10 mM of phosphoric acid （pH 3.29）： acetonitrile （85.7：14.3, v/v） and a flow rate of 1.5 mL/min. Physicochemical characterization by TG, FTIR, and SeM of raw materials of LID, CFX, and eFX provided information useful for the evaluation, differentiation, and qualification of raw materials. Finally, the HPLC method was proved to be useful for evaluation of raw material and finished products, besides satisfying the need for an analytical method that allows simultaneous determination of eFX, CFX, and LID, which can also be extended to other matrices and applications.

关键词： HPLC Physicochemical characterization Quality control Veterinary pharmaceutical formulation Raw material

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Plant growth and nutrient use efficiency of two native Fabaceae species for mineland revegetation in the eastern Amazon

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Journal of Forestry Research 2020年第6期31卷 2287-2293页

作者： Silvio J.Ramos Markus Gastauer Simone K.Mitre Cecı´lio F.Caldeira Joyce R.silva antonio e.Furtini Neto Guilherme Oliveira Pedro W.M.souza Filho Jose´O.Siqueira Instituto Tecnolo´gico Vale Rua Boaventura da Silva955Belem 66055-090Brazil departamento de Ciencia do Solo Universidade Federal de LavrasLavras 37200-000Brazil

The primary challenge of mineland revegetation is the establishment of species able to cope with low availability of nutrients,especially in steep slopes such as of mine *** evaluated plant growth response and nutrient use efficiency(NUe)of two promising native Fabaceae species(Dioclea apurensis—liana from metalliferous savannas;Bauhinia longipedicellata—tree from Amazon rainforest)from the Caraja´s Mineral Province,eastern *** were grown separately in 2-kg pots filled with mining *** were fertilized with nitrogen,phosphorus,potassium(NPK),lime,and *** results showed increments on growth of both species when nutrients were applied to the mining *** showed increases in leaf area,plant height,stem diameter,and shoot dry mass production when NPK or NPK?micronutrients were applied,while *** was responsive to application of NPK?lime or NPK?lime?***,*** showed higher NUe than ***,especially at the lowest doses of N,P and *** findings may indicate a substantial advantage of *** for mineland revegetation,as this species may require lower nutrient inputs,being,therefore,a more sustainable way to revegetate degraded areas.

关键词： Fertilizer application Mining soil Tropical forest Nutrient use efficiency

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evaluating seroprevalence to circumsporozoite protein to estimate exposure to three species of Plasmodium in the Brazilian Amazon

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Infectious Diseases of Poverty 2018年第1期7卷 448-459页

作者： Virginia Araujo Pereira Juan Camilo Sanchez-Arcila Mariana Pinheiro Alves Vasconcelos Amanda Ribeiro Ferreira Lorene de souza Videira antonio Teva Daiana Perce-da-silva Maria Teresa Queiroz Marques Luzia Helena de Carvalho Dalma Maria Banic Luiz Cristovao Sobrino Porto Joseli Oliveira-Ferreira Laboratory of Immunoparasitology Oswaldo Cruz Institute/FiocruzAv.Brasil 4365ManguinhosRio de JaneiroBrazil Institute of Infectology emilio Ribas São PauloSao PauloBrazil Laboratory of Immunodiagnosis Departament of Biological SciencesNational School of Public Health/FiocruzRio de JaneiroBrazil Laboratory of Clinical Immunology Oswaldo Cruz Institute/FiocruzRio de JaneiroBrazil Laboratory of Histocompatibility and Cryopreservation–HLA of DHe/IBRAG/UeRJ Rio de JaneiroBrazil Molecular Biology and Malaria Immunology Research Group Centro de Pesquisas Rene Rachou/FiocruzBelo HorizonteMinas GeraisBrazil

Background:Brazil has seen a great decline in malaria and the country is moving towards ***,for eventual elimination,the control program needs efficient tools in order to monitor malaria exposure and *** this study,we aimed to evaluate whether seroprevalence to the circumsporozoite protein(CSP)is a good tool for monitoring the exposure to and/or evaluating the burden and distribution of Plasmodium species in the Brazilian ***:Cross-sectional surveys were conducted in a rural area of Porto Velho,Rondônia *** infection was detected by microscopy and polymerase chain *** to the sporozoite CSP repeats of Plasmodium vivax,***,and ***(PvCS,PfCS,and PmCS)were detected using the enzyme-linked immunosorbent assay *** leukocyte antigen(HLA)-DRB1 and DQB1 genes were typed using Luminex®xMAP®***:The prevalence of immunoglobulin G against *** CSP peptide(62%)was higher than ***(49%)and ***(46%)CSP *** of the studied individuals had antibodies to at least one of the three peptides(72%),34%had antibodies to all three peptides and 28%were *** the majority of the population was not infected at the time of the survey,74.3%of parasite-negative individuals had antibodies to at least one of the ***,among individuals carrying the haplotypes DRB1*04~DQB1*03,there was a significantly higher frequency of PfCS responders,and DRB1*16~DQB1*03 haplotype for PvCS and PfCS *** contrast,HLA-DRB1*01 and HLA-DQB1*05 allelic groups were associated with a lack of antibodies to *** and *** CSP repeats,and the haplotype DRB1*01~DQB1*05 was also associated with non-responders,including non-responders to ***:Our results show that in low transmission settings,naturally acquired antibody responses against the CSP repeats of ***,***,and *** in a single cross-sectional study may n

关键词： Malaria Circumsporozoite protein Serological marker Human leucocyte antigen IgG antibody Porto Velho Rondônia Brazil

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Thermal Hydraulic Analysis Improvement for the IeA-R1 Research Reactor and Fuel Assembly design Modification

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World Journal of Nuclear Science and Technology 2018年第2期8卷 54-69页

作者： Pedro ernesto Umbehaun Walmir Maximo Torres José antonio Batista souza Mitsuo Yamaguchi antonio Teixeira e silva Roberto Navarro de Mesquita Nikolas Lymberis Scuro delvonei Alves de Andrade Nuclear and energy Research Institute (Instituto de Pesquisas energéticas e Nucleares) S&auml o Paulo Brazil

This paper presents the sequence of activities to improve the thermal hydraulic analysis of the IeA-R1 research reactor to operate in safe conditions after power upgrade from 2 to 5 MW and core size reduction from 30 to 24 fuel assemblies. A realistic analysis needs the knowledge of the actual operation conditions (heat flow, flow rates) beyond the geometric data and the uncertainties associated with manufacturing and measures. A dummy fuel assembly was designed and constructed to measure the actual flow rate through the core fuel assemblies and its pressure drop. First results showed that the flow distribution over the core is nearly uniform. Nevertheless, the values are below than the calculated ones and the core bypass flow rate is greater than those estimated previously. Based on this, several activities were performed to identify and reduce the bypass flow, such as reduction of the flow rate through the sample irradiators, closing some unnecessary secondary holes on the matrix plate, improvement in the primary flow rate system and better fit of the core components on the matrix plate. A sub-aquatic visual system was used as an important tool to detect some bypass flow path. After these modifications, the fuel assemblies flow rate increased about 13%. Additional tests using the dummy fuel assembly were carried out to measure the internal flow distribution among the rectangular channels. The results showed that the flow rate through the outer channels is 10% - 15% lower than the internal ones. The flow rate in the channel formed between two adjacent fuel assemblies is an estimated parameter and it is difficult to measure because this is an open channel. A new thermal hydraulic analysis of the outermost plates of the fuel assemblies takes into account all this information. Then, a fuel design modification was proposed with the reduction of 50% in the uranium quantity in the outermost fuel plates. In order to avoid the oxidation of the outermost plates by high temp

关键词： Nuclear Research Reactor Uranium Reduction Thermal Hydraulic Analysis Flow Measurement Dummy Fuel Assembly

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Genetic and Phenotypic Parameters in the Selection of Upland Rice Genotypes

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American Journal of Plant Sciences 2017年第13期8卷 3450-3459页

作者： Camila Soares Cardoso da silva Flávia Barbosa silva Botelho Cinthia souza Rodrigues Marcela Pedroso Mendes Amanda Mendes de Moura antonio Rosário Neto Federal University of Lavras(UFLA) LavrasBrazil Federal University of Goiás(UFG) GoianiaBrazil

To assist in upland rice breeding programs, estimated genetic and phenotypic parameters are extremely important in the selection of superior lines. Thus, the objective of this study was estimate the genetic and phenotypic parameters of upland rice lines of the breeding program of UFLA in partnership with embrapa Arroz e Feijao and epamig. The experiment was installed in an experimental area of the department of Agriculture at UFLA. It was evaluated 36 upland rice lines of the preliminary trial of the 2014/15 season, in randomized blocks, with three replications and plots consisted of five rows and each row has four meters. For this, it was evaluated the characters: plant height (cm), yield (kg·ha-1), 100-grain weight, days until flowering, percentage of filled grains and rice blast severity. The variance analysis and genetic parameters were estimated using the software SAS. To evaluate the experimental precision was estimated the accuracy, which varied between 63% and 98%, showing experimental precision, moderate to high. The lines differed significantly for all characters, meaning there is genetic variability among genotypes evaluated. With intensity of selection of 10% of lines, it was obtained a genetic gain of 325.29 kg·ha-1 in the character productivity, a plant height (cm) reduction in 5.50 cm, and days until flowering, with a reduction of 9.23 days, with selection of earlier plants. The estimated values for heritability ranged from 38% - 96%. estimates confirm the possible success with the selection of the upland rice lines for these characters.

关键词： Lines Plants Breeding Preliminary Trial Oryza sativa

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