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China Today 2009年第7期58卷 46-47页

作者： sebastien CLERMONT TIMEA FODOR-CLERMONT

WE had heard so much about China, but with such a vast territory, so many people and such a long history, how do you describe China without covering every single aspect of it? How can you sum up the whole of China in ... 详细信息

关键词：中国医疗卫生行业发展现状健康

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Introducing New Peptide Extracts from Saccharomyces cerevisiae and Achatina achatina Fluids with Strong Inhibitory Activities on Human α-Amylase

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Journal of Biosciences and Medicines 2022年第11期10卷 226-239页

作者： Ehuie Micaël Bédikou Fafadzi Charlotte Ehon Chadon Christelle Assémian Djary Michel Koffi Bomo Mondesire Kadjo Allah Antoine Assamoi sebastien Niamké Department of Food Biotechnology Laboratory of Biotechnology Agriculture and Biological Resources Valorization Training and Research Unit in Biosciences University Félix Houphou&euml t-Boigny Abidjan C&ocirc te d’Ivoire

This study aimed at exploring for new natural peptides with strong inhibitory capabilities on α-amylase, the main metabolic enzyme that regulates mellitus diabetes, in order to contribute in controlling this global pandemic. It has consisted in heat shock (to 60°C, 70°C, 80°C, 90°C and 100°C for 10, 20 and 30 minutes) of crude proteins extracted from biomass and extracellular parts of Saccharomyces cerevisiae under cultivation, and from the digestive fluid of the giant snail Achatina achatina, and in-vitro assays of the resulting solutions, as effectors, in human α-amylase catalyzing reactions. The results showed that whatever the temperature and time of treatment, an increase (from 2.65 to 3.98-fold) in proteins concentration was noticed. When blended up to 75 microliters in reaction mixtures, the three peptide extracts showed beyond 11% of inhibition of initial α-amylase activity. By reducing samples volume, only 5 microliters of the studied peptide extracts representing 4.70 μg of S. cerevisiae biomass peptides, 0.55 μg of S. cerevisiae extracellular peptides or 1.05 μg of peptides from the digestive fluid A. achatina were quite sufficient to induce complete (100%) inhibition of the human α-amylase activity. Compared to the inhibitory effect obtained from 2.50 μg of acarbose, a renowned antidiabetic, the studied peptide effectors showed more pronounced inhibitory activities. So, we can positively state that S. cerevisiae as well as A. achatina are both capable of synthesizing proteins made up of small inhibitory peptides which deserve purification and structural analysis for potential exploitation as healthy antidiabetic drugs.

关键词： α-Amylase Inhibitors Healthy Antidiabetics Peptide Drugs Saccharomyces cerevisiae Achatina achatina

Epidemiological profiles of human immunodeficiency virus and hepatitis C virus infections in Malian women:Risk factors and relevance of disparities

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World Journal of Hepatology 2013年第4期5卷 196-205页

作者： Nouhoum Bouare Andre Gothot Jean Delwaide sebastien Bontems Dolores Vaira Laurence Seidel Paul Gerard Christiane Gerard Department of Clinical Biology Laboratory HematologyImmuno-Hematology and AIDS Reference Laboratory B35Centre Hospitalier UniversitaireUniversité de Liège4000 LiègeBelgium Department of Hepatology and Gastroenterology Centre Hospitalier UniversitaireUniversité de Liège4000 LiègeBelgium Department of Public Health(Biostatistics) Centre Hospitalier UniversitaireUniversité de Liège4000 LiègeBelgium Institute of Mathematics Université de Liège4000 LiègeBelgium

AIM:To document the epidemiologic patterns and risk factors of human immunodeficiency virus(HIV)and hepatitis C virus(HCV)infections in Mali in order to develop prevention means for both ***:Two prospective studies were conducted in Bamako in 2009 among 1000 pregnant women(i.e.,young women)who consulted six reference health centers,and in 2010,among 231 older women who attended general practice in two *** tests and molecular analysis(performed only for HCV)were used to quantify the frequencies of both *** data were collected from patients recruited through a *** risk factors of both diseases were identified by univariate and multivariate ***:HCV seroprevalence was 0.2% for young and 6.5% for older *** prevalence was similar in both populations(4.1% vs 6.1%).In older women,the analysis of risk factors highlighted an association between HCV infection and episodes of hospitalization(P < 0.01).The study did not show an association between HIV infection and the variables such as hospitalization,transfusion,tattoo,dental care,and endoscopy.A significant decrease of HIV seroprevalence was detected in young women who used condoms for contraception more than for other purposes(P < 0.01).By contrast,HIV seroprevalence was significantly increased in young women using condoms mainly to prevent sexual infections rather than for contraception(P < 0.01).No HCV/HIV coinfection was detected in our ***:Risk factors and epidemiologic data of HIV and HCV as well as the absence of co-infection strongly suggest epidemiological disparities between these diseases.

关键词： Hepatitis C virus Human immunodeficiency virus Epidemiology Risk factors Women Mali Bamako

Mineralogy and geochemistry of pozzolans from the Tombel Plain,Bamileke Plateau,and Noun Plain monogenetic volcanoes in the central part of the Cameroon Volcanic Line

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Acta Geochimica 2020年第6期39卷 830-861页

作者： Mbowou Ngantche Igor Fulbert Owona sebastien Chako Tchamabe Boris Lissom Justin Lanson Bruno Ekodeck Georges Emmanuel Faculty of Science Department of Earth SciencesUniversity of DoualaP.O.Box 24157DoualaCameroon Faculty of Science Department of GeologyUniversity of Buea.P.O.Box 63BueaCameroon CONACYT-Centro de Ingenieria y Desarrollo Industrial(Sede Campeche) Av.Playa Pie de la Cuesta N°702Desarrollo San PabloP.O.Box.76125QueretaroMexico Institut des Sciences de la Terre(ISTerre) Maison des Sciences de la TerreP.O.Box 5338041 Grenoble Cedex 9France Faculty of Science Department of Earth SciencesUniversity of Yaounde IP.O.Box:812YaoundeCameroon

Pozzolans from the Tombel Plain,Bamileke Plateau,and Noun Plain,3 monogenetic volcanic fields in the central part of the Cameroon Volcanic Line(the Tombel Plain,Bamileke Plateau,and Noun Plain),were explored in order to constrain their petrology and make some predictions on their *** rocks in this study include alkaline and subalkaline basalts,trachybasalts,and *** of these rocks present an overall composition that overlaps with primitive mantle,suggesting rapid ascent of magmas,limited crustal contamination and crystal fractionation of olivine,clinopyroxene,and *** pozzolans present enrichment of LREE relative to HREE and high chondrite normalized ratios of La/Yb and Tb/*** between 7 and 20 and>1.9 respectively,similar to those of Ocean Island *** other nearby volcanoes,partial melting in a dominantly garnet-bearing mantle zone can be *** mineralogy by X-ray diffraction revealed various mineral phases with dominantly plagioclase,augite,olivine,and Fe-Ti *** samples contains important amorphous phase up to 23,51,and 69 wt%in the Tombel Plain,Noun Plain,and Bamileke Plateau,*** elevated amount of amorphous phases together with the sum of SiO2,Al2O3 and total Fe2O3(SAI=68.50-83.50>70 wt%)according to ASTM C618 standard and the sum of CaO,FeO,and MgO(CIM=14.5-30.52 wt%and 23.58-31.08 wt%)suggest interesting pozzolanicity character for the studied pozzolans.

关键词： Pozzolans Mineralogy Geochemistry Pozzolanicity Monogenetic volcanic fields Cameroon Volcanic Line

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Terahertz Non-Contact Monitoring of Cocoa Butter in Chocolate

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World Journal of Engineering and Technology 2018年第2期6卷 268-274页

作者： sebastien Weiller Tadao Tanabe Yutaka Oyama Ecole des Mines d’Albi All&eacute e des sciences Albi France Department of Materials Science Graduate School of Engineering Tohoku University Sendai Japan

Chocolate is widely enjoyed in many sweets and foods all over the world. In cocoa butter, fatty acids combine together and give cocoa butter 6 different types of crystals: γ, α, β’(III), β’(IV), β(V) and β(VI). In the industry, the β(V) form that is required, is metastable and gives chocolate its marketable properties. The β(VI) form is also stable but not desirable, because of fat bloom. The objective of this study is to characterize these polytypes by terahertz(THz) spectroscopy. THz spectroscopy is expected to be a new tool in food industry, as THz energy corresponds to collective molecular macro-vibrations. Two chocolates from different factories were inspected with optical microscope, X-ray diffraction (XRD) and THz spectroscopy. Optical microscope showed different surface aspects, XRD showed the same species in the two brands and THz spectroscopy showed different features. These differences may be due to fatty acids combination of chocolate.

关键词： Chocolate Cocoa Butter Terahertz Spectroscopy Noncontact Monitoring

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爸爸

疯狂英语（初中天地） 2005年第10期 28-29页

作者： sebastien L. 芥子

说起法国人,很多人马上就会联想到浪漫。其实,他们还有一个特点——就是十分热爱自己的文化,并以此为荣,有时还会给人高傲的感觉。我们可以从作者对他的法国爸爸幽默的描写中体会到这种文化差异;另外,文中还出现了很多法国美食,不要错过!

关键词：薄煎饼

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Quality control,validation and user feedback of the European Flood Alert System(EFAS)

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International Journal of Digital Earth 2011年第S1期4卷 77-90页

作者： Ad De Roo Jutta Thielen Peter Salamon Konrad Bogner sebastien Nobert Hannah Cloke David Demeritt Jalal Younis Milan Kalas Katalin Bodis Davide Muraro Florian Pappenberger European Commission Joint Research Centre(JRC)IspraItaly European Centre for Medium Range Weather Forecast(ECMWF) ReadingUK Department of Geography King’s College LondonLondonUK Czech Hydrometeorological Institute PragueCzech Republic

The quality control,validation and verification of the European Flood Alert System(EFAS)are *** is designed as a flood early warning system at pan-European scale,to complement national systems and provide flood warnings more than 2 days before a *** average 2030 alerts per year are sent out to the EFAS partner network which consists of 24 National hydrological authorities responsible for transnational river *** control of the system includes the evaluation of the hits,misses and false alarms,showing that EFAS has more than 50%of the time ***,the skills of both the meteorological as well as the hydrological forecasts are evaluated,and are included here for a 10-year ***,end-user needs and feedback are systematically *** improvements,such as real-time river discharge updating,are currently implemented.

关键词： flood warning forecasting EFAS probabilistic skill

Spatial analysis of bacteria in brackish lake sediment

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International Journal of Sediment Research 2020年第3期35卷 227-236页

作者： Jean-sebastien Beaulne Samir R.Mishra Mrutyunjay Suar Ananta Narayan Panda Gurdeep Rastogi Ajit Kumar Pattnaik Vishakha Raina Timothy M.Vogel Environmental Microbial Genomics Ecole Centrale de LyonUniversite de Lyon ISARA Department of Agroecology and Environment Environmental Biotechnology Laboratory School of BiotechnologyKIIT University Wetland Research and Training Center Chilika Development AuthorityDepartment of Forest and EnvironmentGovernment of Odisha

The spatial distribution of bacterial communities inhabiting sediment is heterogeneous at different spatial scales,but mostly ***,it is postulated that the heterogeneity of the bacterial community composition varies at the same scale of the heterogeneity of sediment chemical *** large spatial scale(km) diversity in sediment from a brackish water lagoon(Chilika Lake,India) is studied,considering the large scale physical and chemical characteristics of land cover,climate,pH,and ***-two samples(24 stations,3 seasons:winter,rainy,and summer) of sediment from Chilika Lake were analyzed by 16 S ribosomal ribonucleic acid(rRNA) gene sequencing,and the relations with land cover and other physico-chemical paramete rs are *** re samples were collected after a severe cyclonic storm(Phailin) passed near the lagoon in 2013,to see the impact of the tropical storm on the spatial and tempo ral distribution of bacteria in the *** results demonstrate clear spatial relations between physico-chemical parameters(e.g.,salinity),land surfaces(e.g.,drainage area),and the distribution of sediment microbial communities.

关键词： Salinity 16S rRNA Macro-scale Sediment GIS

Culture impacts on extrafoveal information use for faces but not for visual scenes

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Culture impacts on extrafoveal information use for faces but...