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Importing Manganese into the Chloroplast： Many Membranes to Cross

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Molecular Plant 2018年第9期11卷 1109-1111页

作者： Anja Krieger-Liszkay sebastien Thomine Institute for Integrative Biology of the Cell (12BC) CEA CNRS Universite Paris-Sud Universite Paris-Saclay Gif-sur-Yvette Cedex 91198 France

Manganese （Mn） plays a wealth of roles in living systems. It is ubiquitously involved in the antioxidant response because of its ability to catalyze the dismutation of superoxide anions. In eukaryotic cells, Mn also plays a role in protein glycosylation in the secretory system. However, arguably, in photosynthetic organisms, the most important role of Mn is in the oxygen evolving complex at photosystem IL （PS Ⅱ）. Atthe global level, atmospheric oxygen is derived from the splitting of water, a reaction that relies strictly on the tetra-manganese cluster （Mn405Ca） bound to photosystem II at the lumen side of the thylakoid membrane.

关键词： PHOTOSYSTEM-II HOMEOSTASIS PHOTOSYNTHESIS PROTEIN ARABIDOPSIS CELLS

High-Order Low Dissipation Conforming Finite-Element Discretization of the Maxwell Equations

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Communications in Computational Physics 2012年第3期11卷 863-892页

作者： sebastien Jund Stephanie Salmon Eric Sonnendrucker IRMA UMR 7501 Universite de Strasbourg and CNRSand CALVI project-teamINRIA Nancy Grand Est7 rue Rene DescartesF-67084 STRASBOURG Cedex Laboratoire de Mathematiques EA 4535 Universite de ReimsU.F.R.Sciences Exactes et NaturellesMoulin de la Housse-BP 1039F-51687 REIMS cedex 2

In this paper,we study high order discretization methods for solving the Maxwell equations on hybrid triangle-quad *** have developed high order finite edge element methods coupled with different high order time schemes and we compare results and efficiency for several *** introduce in particular a class of simple high order low dissipation time schemes based on a modified Taylor expansion.

关键词： Maxwell’s equations edge finite element method mass lumping time discretization schemes

Impact of cavity symmetry on mode suppression and increase of free spectral range in solid-state dye microlaser

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Chinese Optics Letters 2007年第11期5卷 651-653页

作者： Sergei Popov sebastien Ricciardi Ari T.Friberg Sergey Sergeyev Royal Institute of Technology Stockholm 16440 Sweden Waterford Institute of Technology Waterford Ireland

We describe modeling the solid-state dye laser with the microcavity size comparable to light wavelength. Certain symmetry in the allocation of gain material leads to depletion of odd longitudinal modes that, in turn, ... 详细信息

关键词： mode Impact of cavity symmetry on mode suppression and increase of free spectral range in solid-state dye microlaser free

Paleozoic structural and geodynamic evolution of eastern Tianshan （NW China）： welding of the Tarim and Junggar plates

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Episodes 2007年第3期30卷 162-186页

作者： by Jacques Charve Liangshu Shu sebastien Laurent-Charvett ISTO Universite d′Orleans B.P. 6759 45067 Orl6ans Cedex 2 France. Email： Jacques.charvet@univ-orleans.fr State Key Laboratory for Mineral Deposits Research Department of Earth Sciences Nanjing University Nanjing 210093 China. Institut Polytechnique LaSalle Beauvais Site de Cergy-Pontoise - Departement des Geosciences IPSL - 13 bd de rHautil - 95092 Cergy-Pontoise Cedex France.

Chinese East Tianshan is a key area for understanding the Paleozoic accretion of the southern Central Asian Orogenic Belt. A first accretion-collision stage, before the Visean, developed the Eo-Tianshan range, which exhibits north-verging structures. The geodynamic evolution included: i) Ordovician-Early Devonian southward subduction of a Central Tianshan ocean beneath a Central Tianshan arc; ii) Devonian oceanic closure and collision between Central Tianshan arc and Yili-North Tianshan block, along the Central Tianshan Suture Zone; iii) Late Devonian-earliest Carboniferous closure of a South Tianshan back-arc basin, and subsequent Central Tianshan-Tarim active margin collision along the South Tianshan Suture Zone. A second stage involved: i) Late Devonian-Carboniferous south-ward subduction of North Tianshan ocean beneath the Eo-Tianshan active margin (Yili-North Tianshan arc); ii) Late Carboniferous-Early Permian North Tianshan-Junggar collision. The Harlike range, unit of Mongolian Fold Belt, collided with Junggar at Mid-Carboniferous, ending a north-dipping subduction. The last CAOB oceanic suture is likely the North Tianshan Suture Zone, between Yili-North Tianshan and Junggar. During the Permian, all the already welded units suffered from a major wrenching, dextral in Tianshan, sinistral in Mongolian Fold Belt, due to opposite motion of Siberia and Tarim.

关键词：古生代结构地球动力学进化塔里木盆地天山中国

Halogen-specific total organic halogen analysis： Assessment by recovery of total bromine

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Journal of Environmental Sciences 2017年第8期29卷 340-348页

作者： Markus Langsa sebastien Allard Ina Kristiana Anna Heitz Cynthia A.Joll Curtin Water Quality Research Centre Department of Chemistry Curtin University Perth Western Australia 6102 Australia Department of Civil Engineering Curtin University Perth Western Australia 6102 Australia Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan AlamUniversitas PapuaManokwaripapua Barat 98314Indonesia

Determination of halogen-specific total organic halogen（TOX） is vital for studies of disinfection of waters containing bromide, since total organic bromine（TOBr） is likely to be more problematic than total organic chlorine. Here, we present further halogen-specific TOX method optimisation and validation, focusing on measurement of TOBr. The optimised halogen-specific TOX method was validated based on the recovery of model compounds covering different classes of disinfection by-products（haloacetic acids, haloacetonitriles,halophenols and halogenated benzenes） and the recovery of total bromine（mass balance of TOBr and bromide concentrations） during disinfection of waters containing dissolved organic matter and bromide. The validation of a halogen-specific TOX method based on the mass balance of total bromine has not previously been reported. Very good recoveries of organic halogen from all model compounds were obtained, indicating high or complete conversion of all organic halogen in the model compound solution through to halide in the absorber solution for ion chromatography analysis. The method was also successfully applied to monitor conversion of bromide to TOBr in a groundwater treatment plant. An excellent recovery（101%）of total bromine was observed from the raw water to the post-chlorination stage. Excellent recoveries of total bromine（92%–95%） were also obtained from chlorination of a synthetic water containing dissolved organic matter and bromide, demonstrating the validity of the halogen-specific TOX method for TOBr measurement. The halogen-specific TOX method is an important tool to monitor and better understand the formation of halogenated organic compounds, in particular brominated organic compounds, in drinking water systems.

关键词： Total organic bromine Dissolved organic matter Bromide Chlorination Drinking water Health effects

Giant dedifferentiated liposarcoma of the gastrocolic ligament:A case report

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World Journal of Gastrointestinal Surgery 2023年第10期15卷 2376-2381页

作者： Assamoi Brou Fulgence Kassi Kacou sebastien Yenon Fian Marc Herve Kassi Adja Jacob Adjeme Khader Morel Diarra Cynthia Bombet-Kouame Marcellin Kouassi Surgery and Surgical Specialities Medical Sciences Training and Research UnitAbidjan Felix Houphouet-Boigny UniversityAbidjan 01 BP V 34Cote d'Ivoire Surgery and Surgical Specialities Digestive Surgery UnitUniversity Hospital of CocodyAbidjan 01 BP V13Cote d'Ivoire

BACKGROUND Dedifferentiated liposarcoma(DDLS)has a worse prognosis and occurs most commonly in the retroperitoneal region and rarely in the intraperitoneal *** diagnosis was revolutionized by the combined contributions of histoimmuno-chemistry and molecular *** from surgery,there is no consensus on the optimal treatment for this chemoresistant *** SUMMARY A thirty-year-old black female presented with a large painful abdominal mass occupying nearly the entire abdomen and progressive weight loss was admitted for *** computed tomography showed a large heterogeneous mass of the mesentery that was sized 18 cm×16 cm in size and had heterogeneous contrast *** laparotomy,en bloc excision of the large and multilobulated gastrocolic ligament mass was *** initial postoperative histopathological diagnosis was undifferentiated ***,the results of immunohistochemistry and molecular biology allowed us to confirm the diagnosis of *** tumour followed an aggressive evolution with diffuse metastasis,causing the death of the patient less than 5 mo after the *** Dedifferentiated liposarcomas are rare tumours that typically originate in the retroperitoneum but may arise in unexpected locations.

关键词： Dedifferentiated liposarcoma Gastrocolic ligament mass En bloc excision Immunohistochemistry Molecular biology Worse prognosis Case report

Can earthen architectural heritage save us?

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Built Heritage 2021年第3期5卷 99-109页

作者： sebastien Moriset Bakonirina Rakotomamonjy David Gandreau Centre international de la construction en terre Ecole Nationale Supérieure d’architecture de GrenobleCRAterreCS 12636‑38036 GRENOBLECedex 2France

Contemporary architecture seems to turn its back on the past in terms of the raw materials taken from the environ‑ment,their transformation into building components and the way they are assembled to create *** global challenge of preserving the environment forces us to rethink the way we produce architecture *** this challenge,the past shows us possible ways to fll the gap between tradition and ***,we need to understand what motivates people to abandon ancestral materials and knowledge for materials that they cannot manufacture or use *** this transformation to industrial materials and forms irreversible?Is there nothing we can learn from our rich past?How can we revive endogenous knowledge to produce environmentally wise archi‑tecture?These are the questions that the authors,who have been working on the revival of earthen heritage for over 20 years,wish to answer.

关键词： Learning from the past Endogenous knowledge Earthen architecture Sustainable architecture

Construction and Analysis of an Adapted Spectral Finite Element Method to Convective Acoustic Equations

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Communications in Computational Physics 2016年第6期20卷 1-22页

作者： Andreas Huppe Gary Cohen sebastien Imperiale Manfred Kaltenbacher TU Wien Institute of Mechanics and MechatronicsGetreidemarkt 9/E3251060WienAustria Inria-CNRS-ENSTA Saclay Ile-de-France91120 PalaiseauFrance Inria Saclay Ile-de-France91120 PalaiseauFrance

The paper addresses the construction of a non spuriousmixed spectral finiteelement(FE)method to problems in the field of computational *** a computational scheme for the conservation equations of linear acoustics,the extensiontowards convected wave propagation is *** aeroacoustic applications,the mean flow effects can have a significant impact on the generated soundfield even for smaller Mach *** those convective terms,the initial spectralFE discretization leads to non-physical,spurious ***,a regularizationprocedure is proposed and qualitatively investigated bymeans of discrete eigenvaluesanalysis of the discrete operator in space.A study of convergence and an applicationof the proposed scheme to simulate the flow induced sound generation in the processof human phonation underlines stability and validity.

关键词： Spectral finite elements aeroacoustics perturbation equations

Iron and liver fibrosis: Mechanistic and clinical aspects

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World Journal of Gastroenterology 2019年第5期25卷 521-538页

作者： Kosha J Mehta sebastien Je Farnaud Paul A Sharp School of Population Health and Environmental Sciences Faculty of Life Sciences and Medicine King’s College London Division of Human Sciences School of Applied Sciences London South Bank University Faculty Research Centre for Sport Exercise and Life Sciences Coventry University Department of Nutritional Sciences School of Life Course Sciences Faculty of Life Sciences and Medicine King's College London

Liver fibrosis is characterised by excessive deposition of extracellular matrix that interrupts normal liver functionality. It is a pathological stage in several untreated chronic liver diseases such as the iron overload syndrome hereditary haemochromatosis, viral hepatitis, alcoholic liver disease, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis and diabetes. Interestingly, regardless of the aetiology, iron-loading is frequently observed in chronic liver diseases. Excess iron can feed the Fenton reaction to generate unquenchable amounts of free radicals that cause grave cellular and tissue damage and thereby contribute to fibrosis. Moreover, excess iron can induce fibrosis-promoting signals in the parenchymal and non-parenchymal cells, which accelerate disease progression and exacerbate liver pathology. Fibrosis regression is achievable following treatment, but if untreated or unsuccessful, it can progress to the irreversible cirrhotic stage leading to organ failure and hepatocellular carcinoma, where resection or transplantation remain the only curative options. Therefore,understanding the role of iron in liver fibrosis is extremely essential as it can help in formulating iron-related diagnostic, prognostic and treatment strategies. These can be implemented in isolation or in combination with the current approaches to prepone detection, and halt or decelerate fibrosis progression before it reaches the irreparable stage. Thus, this review narrates the role of iron in liver fibrosis. It examines the underlying mechanisms by which excess iron can facilitate fibrotic responses. It describes the role of iron in various clinical pathologies and lastly,highlights the significance and potential of iron-related proteins in the diagnosis and therapeutics of liver fibrosis.

关键词： Iron Liver pathologies Liver fibrosis Hepatic stellate cells Cirrhosis