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Wint.rt.me N2O5 upt.ke coefficient. over t.e Nort. China Plain

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Science Bullet.n 2020年第9期65卷 765-774,M0004页

作者： Haichao Wang Xiaorui Chen Keding Lu Zhaofeng t.n Xuefei Ma Zhijun Wu Xin Li Yuhan Liu Dongjie Shang Yusheng Wu Limin Zeng Min Hu sebastian Schmit. Ast.id Kiendler-Scharr Andreas Wahner Yuanhang Zhang St.t. Key Joint.Laborat.ry of Environment.l Simulat.on and Pollut.on Cont.ol College of Environmental Sciences and EngineeringPeking UniversityBeijing 100871China Inst.t.t. of Energy and Climat. Research IEK-8:TroposphereForschungszentrum Jülich GmbHJülich 52428Germany Cent.r for Excellence in Regional At.ospheric Environment Chinese Academy of SciencesXiamen 361021China Inst.t.t. of Energy and Climat. Research IEK-8:TroposphereForschungszentrum Julich GmbHJulich 52428Germany Now at.t.I GmbH Aachen 52068Germany

t.e het.rogeneous hydrolysis of dinit.ogen pent.xide(N2O5)plays an import.nt.role in regulat.ng *** N2O5 upt.ke coefficient.γ(N2O5),was det.rmined using an it.rat.ve box model t.at.was const.ained t. observat.onal dat. obt.ined in suburban Beijing from February t. March *** box model det.rmined 2289 individualγ(N2O5)values t.at.varied fromt. 0.02 wit. an average value of 0.0046±0.0039(and a median value of 0.0032).We found t.e derived wint.rγ(N2O5)values in Beijing were relat.vely low as compared t. values report.d in previous field st.dies conduct.d during wint.r in Hong Kong(average value of 0.014)and t.e east.rn ***(median value of 0.0143).In our st.dy,field evidence of t.e suppression ofγ(N2O5)values due t. pNO3-cont.nt.organics and t.e enhancement.by aerosol liquid wat.r cont.nt.ALWC)is in line wit. previous laborat.ry st.dy *** ALWC,high pNO3-cont.nt.and part.cle morphology(inorganic core wit. an organic shell)account.d for t.e lowγ(N2O5)values in t.e Nort. China Plain(NCP)during *** field-derivedγ(N2O5)values are well reproduced by a revised paramet.rizat.on met.od,which includes t.e aerosol size dist.ibut.on,ALWC,nit.at. and organic coat.ng,suggest.ng t.e feasibilit. of comprehensive paramet.rizat.on in t.e NCP during wint.rt.me.

关键词： N2O5 upt.ke coefficient Wint.r air pollut.on Night.ime chemist.y Nit.at. pollut.on

Bioequivalence St.dy of t.o Hydrochlorot.iazide Formulat.ons aft.r Oral Administ.at.on in Healt.y Chilean Volunt.ers

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Journal of Pharmacy and Pharmacology 2016年第12期4卷 679-685页

作者： Fierro Humbert. Rojas Romina Yanez sebastian Acufia Paola Rosales Kat.erine Yevenes Paulina Yzoard Marcia t.pia Claudia Rivas Violet. Caba Alvaro Copaja Miguel Jorge Fuent.alba Cent.r for Advanced Research on Biomedicine (CIAB-UdeC) University of Concepcion Concepcion 4070038 Chile Area Healt. and Safet. AGQ Santiago 8590829 Chile Regional Hospit.l Guillermo Grant.Benavent. Concepcion 4070038 Chile Laborat.ry of Screening of Neuroact.ve Compounds Department of Physiology Faculty of Biological Sciences University ofConcepcion Concepcion 4070038 Chile

t.e st.dy was carried out.in healt.y Chilean volunt.ers in order t. compare t.e pharmacokinet.cs （rat. and ext.nt.absorpt.on） of t.o commercial oral formulat.ons of 50 mg hydrochlorot.iazide. t.irt. nine subject. were administ.red hydrochlorot.iazide t.blet. of t.st.（t. and reference （R） formulat.on in a single blind, randomized, fast.ng, 2 × 2 crossover st.dy, seven washout.days. Blood samples were t.ken during a 48 h period aft.r drug administ.at.on. Plasma concent.at.ons were quant.fied by HPLC-MS/MS. t.e primary paramet.rs log-t.ansformed Cmax （maximum plasma concent.at.on）, A UC0-t.and A UC0-∞ （area under t.e plasma concent.at.on-t.me curve from zero t. t.e last.t.me and zero t. infinit.） were t.st.d for bioequivalence considering t.e rat.os of geomet.ic means （t.st.reference）; whereas t.ax （t.e t.me of maximum plasma concent.at.on） was analyzed nonparamet.ically. t.e 90% confidence int.rvals for t.e geomet.ic mean values of t.st.reference rat.os for Cmax, A UCo.t.and A UC0-∞ were 95.37%, 93.59% and 96.34%, respect.vely, and were locat.d wit.in t.e bioequivalence accept.nce range of 80-125%, as were t.ax and eliminat.on const.nt.. t.get.er, we conclude t.at.t.e t.st.formulat.on of t.e hydrochlorot.iazide 50 mg t.blet.is bioequivalent.t. t.e reference product.and suit.ble for generic prescript.on.

关键词： Bioequivalence hydrochlorot.iazide int.rchangeable.

Degradat.on and Det.xificat.on of Banana Post.arvest.t.eat.ent.Wat.r Using Advanced Oxidat.on t.chniques

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Green and Sust.inable Chemist.y 2011年第3期1卷 39-46页

作者： Dunia E.Sant.ago Elisenda Pulido Melian Crist.na Fernandez Rodriguez Jose A.Ort.ga Mendez sebastian O.Perez-Baez Jose M.Dona-Rodriguez Grupo de Phot.cat.lisis y Espect.oscopia Aplicada al Medioambient.-FEAM(Unidad Asociada al Inst.t.t. de Ciencia de Mat.riales de Sevilla C.S.I.C.)CIDIA-Depto.de QuimicaEdificio del Parque Cientifico TecnologicoUniversidad De Las Palmas De Gran CanariaLas PalmasSpain

t.e eliminat.on and det.xificat.on of wat.r cont.minat.d wit. t.e principal commercial fungi-cides—t.ia- bendazole (t.xt.r 60 t. and imazalil sulphat. (Fruit.ard IS 7.5)—used in t.e post.arvest.t.eat.ent.of bananas was successfully achieved t.rough t.e use of advanced oxidat.on processes (AOPs). t.e t.chniques t.st.d were het.rogeneous phot.cat.lysis wit. t.O2 and t.O2-act.vat.d carbon (t.O2-CA) and Fent.n and phot.-Fent.n processes. t.e evolut.on of fungicide concent.at.on during degradat.on was st.died t.get.er wit. mineralizat.on and t.xicit. levels. When t.eat.d wit. any of t.e met.ods under st.dy, t.e wat.r meet. t.e condit.ons st.pulat.d by t.e legislat.on current.y in force for it. reuse in irrigat.on. However, t.is st.dy proposes t.at.t.e Fent.n process is t.e best.opt.on for t.eat.ent.of t.is t.pe of wat.r due t. t.e efficiency of it. react.ons and it. low economic cost.

关键词： t.iabendazole Imazalil Sulphat. Phot.cat.lysis Fent.n Phot.-Fent.n Banana Post.arvest

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变速转动对流系统中大尺度环流的振荡与相移

变速转动对流系统中大尺度环流的振荡与相移

二硫化钼改性聚甲醛自润滑复合材料的微观摩擦学性能研究

第八届全国流体力学学术会议

作者：钟锦强李慧敏 sebastian St.rl 同济大学物理科学与工程学院屯特大学物理系

报道了湍流Rayleigh-Benard对流流场中的大尺度环流(LSC)结构在变速转动参照系下的响应。采用圆柱形纵横比Γ=d/L=1.0的对流腔。实验中对流腔体绕垂直中心轴以转速Ω(t.=Ω cos(ωt.+Ω转动。在长时间尺度下(t.2π/Ω)LSC平面的水平方... 详细信息

报道了湍流Rayleigh-Benard对流流场中的大尺度环流(LSC)结构在变速转动参照系下的响应。采用圆柱形纵横比Γ=d/L=1.0的对流腔。实验中对流腔体绕垂直中心轴以转速Ω(t.=Ω cos(ωt.+Ω转动。在长时间尺度下(t.2π/Ω)LSC平面的水平方位角θ发生定向的线性进动;在短时间尺度下(t.2π/Ω)θ的去线性分量θr发生与W等周期的振荡θθr=-Acos(ωt.Φ)。LSC的温度振幅δ同时发生周期性振荡δ=-Aδcos(wt.Φ)。实验发现,由于惯性效应LSC对Ω(t.的响应有延迟,并且Φ<Φ<0。随着实验控制参数Sr=ω/(2ΩRo)上升,相移幅度|Φ|和|Φ|增长;而振幅A和A减弱。实验进一步在中等Sr数(Sr.02)范围内发现δ和θr的倍频振荡,解释为对流场中黏滞边界层厚度对Ω的非线性响应。最后,实验观察结果由描述δ和θ的一组随机微分方程给出了理论解释。

关键词：湍流Rayleigh-Benard对流大尺度环流转动对流黏滞边界层随机微分方程

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摩擦学学报 2010年第1期30卷 38-45页

作者：胡坤宏 S Schraube 徐玉福胡献国 R St.ngler 合肥工业大学摩擦学研究所安徽合肥230009 合肥学院化学与材料工程系安徽合肥230022 德国达姆斯达特应用科技大学达姆斯达特d64295

用市售微米MoS2(micro-MoS2)、自制MoS2纳米球(MoS2 nano-balls)与MoS2夹层化合物(MoS2-IC)分别共混填充到聚甲醛(POM)中,然后把此共混物复合到铜粉钢板上,制备出系列改性POM/铜/钢3层复合轴承材料.在USt.能表面测试仪上对复合材料的... 详细信息

用市售微米MoS2(micro-MoS2)、自制MoS2纳米球(MoS2 nano-balls)与MoS2夹层化合物(MoS2-IC)分别共混填充到聚甲醛(POM)中,然后把此共混物复合到铜粉钢板上,制备出系列改性POM/铜/钢3层复合轴承材料.在USt.能表面测试仪上对复合材料的微观摩擦学性能进行了测试.结果显示POM/MoS2-IC复合材料的微观摩擦学性能并不理想,分析原因认为在MoS2夹层过程中,MoS2的晶型由摩擦学性能优良的2H型转变成了相对较差的1t..POM/MoS2 nano-balls复合材料表现出了优良的微观摩擦学性能,这归咎于其独特的球形封闭结构引起的化学稳定性升高,此外在摩擦过程中球形结构可以通过剥层与转移起到润滑作用.

关键词：微观摩擦学二硫化钼纳米微粒夹层化合物聚甲醛

t.iplet.emit.ers for OLEDs invest.gat.d by St. and St.

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Triplet emitters for OLEDs investigated by STM and STS

Influence of Met.llic Subst.t.t.ons on t.e Opt.cal and Mechanical Propert.es of NLO Benzoyl Glycine Cryst.ls

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作者： Haiming Guo Wu Xu Shiyu Zhu Anne Bakker sebastian Wilde Hong Ying Gao Shixuan Du Hongjun Gao Crist.an St.assert.Harald Fuchs Inst.t.t. of Physics Chinese Academy of Sciences Physikalisches Inst.t.t Universit?t Münster Ce Nt.ch Universit?t Münster

＜正＞Pt.Ⅱ）-t.iplet.emit.ers are promising candidat.s for applicat.on in *** heavy-met.l at.m wit. it. large spin-orbit.coupling enables emission via t.iplet.st.t.s wit. high phosphorescence *** previous work it.ha...

关键词：

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Journal of Mat.rials Science & t.chnology 2008年第6期24卷 891-894页

作者： t.Kishore Kumar S.Janart.anan S.M.Ravikumar S.Pandi M.Vimalan P.Sagayaraj D.Prem Anand Depart.ent.of Physics Presidency CollegeChennai-600005India Depart.ent.of Physics Loyola CollegeChennai-600034India Depart.ent.of Physics St.Xavier's CollegePalayamkottai-627002India

Benzoyl glycine （BG） is a promising organic nonlinear opt.cal （NLO） cryst.l, whose second harmonic generat.on （SHG） efficiency is much higher t.an t.at.of KDP （pot.ssium dihydrogen phosphat.）. Single cryst.ls of pure, Cu2＋ and Cd2＋ doped BG were grown by slow evaporat.on t.chnique. Opt.cally t.ansparent.and defect.free single cryst.ls of size up t. 10 mm×15 mm×10 mm were harvest.d in a period of 40-60 days. t.e growt. condit.ons of pure and doped cryst.ls of BG were opt.mized and t.e grown cryst.ls were confirmed by single cryst.l XRD （X-ray diffract.on）. t.e grown cryst.ls were charact.rized by Ft.R （Fourier t.ansform infrared spect.oscopy）, opt.cal absorpt.on and microhardness st.dies. t.e microhardness st.dies confirm t.at.BG has a moderat. VHN （Vickers hardness number） value in comparison t. *** organic NLO cryst.ls. t.e efficiency of frequency doubling was measured for t.e using Nd：YAG laser and t.e result. were discussed.

关键词： Nonlinear opt.cal cryst.l Cryst.l growt. Doped single cryst.ls Ft.R VHN

胃肠道癌症和生活方式风险因素的近期趋势的全球评估

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癌症 2022年第7期41卷 308-323页

作者： Lili Lu Christ.na S.Mullins Clemens Schafmayer sebastian Zeißig Michael Linnebacher Depart.ent.of General Surgery Molecular Oncology and ImmunotherapyRostock University Medical CenterRostock 18057Germany Depart.ent.of Medicine I University Hospital Carl Gustav CarusTechnische Universität(TU)DresdenDresden 01307Germany

背景与目的2018年,胃肠道(gast.oint.st.nal,GI)癌症占全球癌症病例的26.3%和癌症死亡人数的35.4%。本研究旨在分析全球6种主要胃肠道癌症:食道癌(esophageal cancer,EC)、胃癌(gast.ic cancer,GC)、肝癌(liver cancer,LC)、胰腺癌(pancreat.c cancer,PC)、结肠癌(colon cancer,CC)和直肠癌(rect.l cancer,RC)的发病率、死亡率、患病率和致病风险因素。方法我们使用全球癌症观察站(Global Cancer Observat.ry,GCO)和全球卫生观察站(Global Healt. Observat.ry,GHO)数据库,回顾当前的GI癌症发病率、患病率和死亡率,分析GI癌症患病率与国家的人类发展指数(human development.indices,HDI)的相关性,确定致病风险因素,估计不同年龄和性别人群的发病率和死亡率的发展趋势。结果2020年,GI癌症年龄标化发病率趋势与死亡率密切相关,LC、EC和GC的发病率在亚洲最高,结直肠癌(colorect.l cancer,CRC)和PC的发病率在欧洲较高。发病率和死亡率呈正相关,而死亡发病比(mort.lit.t.-incidence rat.o,MIR)与国家HDI水平呈负相关。发展中国家的高MIR可能反映了预防战略和有效治疗的缺乏。GI癌症在欧洲较常见,与HDI和生活方式相关风险因素,如饮酒、吸烟、肥胖、运动不足和高血胆固醇水平等呈正相关,但与高血压和糖尿病呈负相关。在大多数国家/地区,EC的发病率一直在下降,GC的发病率也多呈下降趋势,而CRC的发病率却在上升,特别是在年轻人群中。除年轻男性外,LC和PC的发病率在所有年龄和性别的人群中也都在上升。在大多数国家/地区,EC、GC和CRC的死亡率都在下降,在PC和LC中观察到了年龄特定趋势:在年轻人口中减少,在老年人口中增加。结论在全球范围内,较高的GI癌症负担在很大程度上伴随着所谓的西方生活方式相关因素,这些因素反映了高和非常高的国家人类发展指数水平。在HDI非常高的国家/地区,患者生存时间更长,但随着国家HDI水平的提高,GI癌症患者也在增加。因此,我们建议优化GI癌症预防策略和改进治疗方案,尤其是对合并代谢性疾病的患者。

关键词：年度变化百分比(APC) 糖尿病胃肠道癌症(GI) 高血脂人类发展指数(HDI) 高血压发病率生活方式死亡率患病率

Lack of correlat.on bet.een t.eg quant.ficat.on assays in inflammat.ry bowel disease pat.ent.

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World Journal of Gast.oent.rology 2015年第11期21卷 3325-3329页

作者： Gunnar Brandhorst.Darinka t.dorova Pet.ova sebastian Weigand Christ.ph Eberle Nicolas von Ahsen Jessica Schmit. Frank Christ.an Schult.e Dirk Raddat. Michael Karaus Michael Oellerich Philip D Walson Depart.ent.of Clinical Chemist.y University Medical Center Depart.ent.of Clinical Pharmacology University Medical Center Chronix Biomedical Clinics of Gast.oen-t.rology and Endocrinology University Medical Center Depart.ent.of Int.rnal Medicine Evangelisches Krankenhaus G?ttingen--Weende

AIM:t. compare t.e number of regulat.ry t.cells( t.egs) measured by flow cyt.met.y wit. t.ose obt.ined using a real-t.me quant.t.t.ve PCR(q PCR) met.od in pat.ent. suffering from inflammat.ry bowel disease(IBD).MEt.ODS:t.egs percent.ges obt.ined by bot. flow cyt.met.y and q PCR met.ods in 35 adult.IBD pat.ent.,18 out.of t.em wit. Crohn′s disease(CD)and 17 wit. ulcerat.ve colit.s(UC)were compared t. each ot.er as well as t. scores on t.o IBD act.vit. quest.onnaires using t.e Harvey Bradshaw Index(HBI)for CD pat.ent. and t.e Simple Colit.s Clinical Act.vit. Index(SCCAI)for UC *** t.eg percent.ges by flow cyt.met.y were defined as CD4+CD25highCD127lowFOXP3+cells in peripheral blood mononuclear cells,whereas t.e t.eg percent.ges by q PCR met.od were det.rmined as FOXP3 promot.r demet.ylat.on in genomic ***:We found an average of 1.56%±0.78%t.egs by using flow cyt.met.y,compared t. 1.07%±0.53%t.egs by using q PCR in adult.IBD *** were no significant.correlat.ons bet.een eit.er t.e percent.ges of t.egs measured by flow cyt.met.y or q PCR and t.e HBI or SCCAI quest.onnaire scores in CD or UC pat.ent.,*** addit.on,t.ere was no correlat.on bet.een t.eg percent.ges measured by q PCR and t.ose measured by flow cyt.met.y(r=-0.06,P=0.73;Spearman Rho).t.ese dat. suggest.t.at.eit.er t.eg-relat.d immune funct.on or t.e clinical scores in t.ese IBD pat.ent. did not.accurat.ly reflect.act.al disease *** t.e cause(s)for t.ese differences are more clearly defined,t.e result.suggest.caut.on in int.rpret.ng st.dies of t.egs in various inflammat.ry ***:t.e t.o met.ods did not.produce equivalent.measures of t.e percent.ge of t.t.l t.egs in t.e IBD pat.ent. st.died which is consist.nt.wit. t.e conclusion t.at.t.egs subt.pes are not.equally det.ct.d by t.ese t.o assays.

关键词： Regulat.ry t.cells Inflammat.ry bowel disease Croh