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Areas of research and clinical approaches to the study of liver abscess

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World Journal of Gastroenterology 2017年第2期23卷 357-365页

作者： Gregorio gonzález-Alcaide Jorge peris José Manuel Ramos Department of History of Science and Documentation University of Valencia Deparment of Internal Medicine Hospital Universitario Sant Joan d’Alacant Departament of Clinical Medicine Universidad Miguel Hernández de Elche Department of Internal Medicine Hospital General Universitario de Alicante

AIM To analyze the research activity on liver abscess(LA) and identify the main topic clusters in the area. METHODS We identified all documents using the medical subject heading "LA" indexed in the MEDLINE database between 2001 and 2015. We performed a descriptive bibliometric analysis, characterizing the evolution of scientific activity, the publication types of the documents, the document categories of clinical interest(case reports, clinical trials, evaluation studies, meta-analysis, observational studies, practice guidelines and validation studies) and the geographic distribution of the research. We also carried out an analysis of networks and research clusters in order to identify the main topic areas of *** Our search yielded a total of 1278 documents, showing a stable scientific production over the study period and a marked multidisciplinary nature. The research was dominated by case reports(65.9% of the documents analyzed). In terms of geographic distribution, researchers from the United States led in the number of signatures(n = 229), followed by those from Taiwan(n= 185), India(n = 145), Japan(n = 144), South Korea(n = 100), and China(n = 84). With regard to amebic LA, the top-producing countries were India and Mexico(n = 69 each), followed by the United States(n = 29). In the case of pyogenic LA, Taiwan Residents researchers led scientific production(n = 71), followed by the United States(n = 39) and China(n = 29). The most active areas of research in the field are diagnosis via computerized tomography scan, differential diagnosis with regard to liver cancer, treatment with antimicrobial agents, and Klebsiella infections(including bacteremia).CONCLUSION Clinical case reports associated with diagnosis and treatment are the main topic of study, highlighting the importance of this document type in advancing knowledge.

关键词：肝脓肿聚类分析阿米巴的脓肿 Pyogenic 脓肿 Bibliometrics

Right ventricle dysfunction does not predict mortality in patients with SARS-CoV-2-related acute respiratory distress syndrome on extracorporeal membrane oxygenation support

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World Journal of Cardiology 2023年第4期15卷 165-173页

作者： Chiara Lazzeri Manuela Bonizzoli Stefano Batacchi Giovanni Cianchi Andrea Franci Filippo Socci Marco Chiostri Adriano peris ICU and ECMO Center Florence 50134Italy

BACKGROUND The prognostic role of right ventricle dilatation and dysfunction(RVDD)has not been elucidated in patients with coronavirus disease(COVID)-related respiratory failure refractory to standard treatment needing extracorporeal membrane oxygenation(ECMO)*** To assess whether pre veno-venous(VV)ECMO RVDD were related to inintensive care unit(ICU)*** We enrolled 61 patients with COVID-related acute respiratory distress syndrome refractory to conventional treatment submitted to VV ECMO and consecutively admitted to our ICU(an ECMO referral center)from 31th March 2020 to 31th August *** echocardiographic exam was performed immediately before VV ECMO *** Males were prevalent(73.8%)and patients with a body mass index>30 kg/m^(2) were the majority(46/61,75%).The overall in-ICU mortality rate was 54.1%(33/61).RVDD was detectable in more than half of the population(34/61,55.7%)and associated with higher simplified organ functional assessment(SOFA)values(P=0.029)and a longer mechanical ventilation duration prior to ECMO support(P=0.046).Renal replacement therapy was more frequently needed in RVDD patients(P=0.002).A higher in-ICU mortality(P=0.024)was observed in RVDD *** echo variables were independent predictors of in-ICU *** In patients with COVID-related respiratory failure on ECMO support,RVDD(dilatation and dysfunction)is a common finding and identifies a subset of patients characterized by a more severe disease(as indicated by higher SOFA values and need of renal replacement therapy)and by a higher in-ICU ***(also when considered separately)did not result independently associated with in-ICU mortality in these patients.

关键词： Right ventricle Echocardiography Mortality COVID Acute respiratory distress syndrome Right ventricle-pulmonary circulation coupling

Haemodynamic management in brain death donors:Influence of aetiology of brain death

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World Journal of Transplantation 2023年第4期13卷 183-189页

作者： Chiara Lazzeri Manuela Bonizzoli Stefano Batacchi Cristiana Guetti Walter Vessella Alessandra Valletta Alessandra Ottaviano Adriano peris Department of Emergency Intensive Care Unit and Extracorporeal Membrane Oxygenation CenterFlorence 50134Italy

BACKGROUND In brain death donors(BDDs),donor management is the key in the complex donation *** management goals,which are standards of care or clinical parameters,have been considered an acceptable barometer of successful donor *** To test the hypothesis that aetiology of brain death could influence haemodynamic management in *** Haemodynamic data(blood pressure,heart rate,central venous pressure,lactate,urine output,and vasoactive drugs)of BDDs were recorded on intensive care unit(ICU)admission and during the 6-h observation period(Time 1 at the beginning;Time 2 at the end).RESULTS The study population was divided into three groups according to the aetiology of brain death:Stroke(n=71),traumatic brain injury(n=48),and postanoxic encephalopathy(n=19).On ICU admission,BDDs with postanoxic encephalopathy showed the lowest values of systolic and diastolic blood pressure associated with higher values of heart rate and lactate and a higher need of norepinephrine and other vasoactive *** the beginning of the 6-h period(Time 1),BDDs with postanoxic encephalopathy showed higher values of heart rate,lactate,and central venous pressure together with a higher need of other vasoactive *** According to our data,haemodynamic management of BDDs is affected by the aetiology of brain *** with postanoxic encephalopathy have higher requirements for norepinephrine and other vasoactive drugs.

关键词： Brain death donor Postanoxic encephalopathy Stroke Acute traumatic injury Haemodynamic management Utilization rate

Robot-assisted kidney transplantation:Is it getting ready for prime time?

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World Journal of Transplantation 2022年第7期12卷 163-174页

作者： Vincenzo Li Marzi Alessio Pecoraro Maria Lucia Gallo Leonardo Caroti Adriano peris Graziano Vignolini Sergio Serni Riccardo Campi Department of Minimally Invasive and Robotic Urologic Surgery Careggi University HospitalUniversity of FlorenceFlorence 50134Italy Nephrology Unit Careggi HospitalFlorence 50134Italy Intensive Care Unit and Regional ECMO Referral Centre Careggi HospitalFlorence 50134Italy Department of Minimally Invasive and Robotic Urologic Surgery University of FlorenceFlorence 50134Italy Department of Experimental and Clinical Medicine University of FlorenceFlorence 50134Italy

Kidney transplantation(KT)is the treatment of choice for patients with end-stage renal disease,providing a better survival rate and quality of life compared to *** the progress in the medical management of KT patients,from a purely surgical standpoint,KT has resisted innovations during the last 50 ***,robot-assisted KT(RAKT)has been proposed as an alternative approach to open surgery,especially due to its potential benefits for fragile and immunocompromised *** was not until 2014 that the role of RAKT has found value thanks to the pioneering Vattikuti Urology Institute-Medanta collaboration that conceptualized and developed a new surgical technique for RAKT following the Idea,Development,Exploration,Assessment,Long-term follow-up recommendations for introducing surgical innovations into real-life *** the last years,mirroring the Vattikuti-Medanta technique,several centers developed RAKT program worldwide,providing strong evidence about the safety and the feasibility of this ***,the majority of RAKT are still performed in the living donor setting,as an“eligible”procedure,while only a few centers have realized KT through a robotic approach in the challenging scenario of cadaver *** addition,despite the spread of minimally-invasive(predominantly robotic)surgery worldwide,many KTs are still performed in an open *** of the type of incision employed by surgeons,open KT may lead to nonnegligible risks of wound complications,especially among obese ***,the assessment for KT should consider not only the added surgical technical challenges but also the higher risk of postoperative *** this context,robotic surgery could offer several benefits,including providing a better exposure of the surgical field and better instrument maneuverability,as well as the possibility to integrate other technological nuances,such as the use of intraoperative fluorescence vascular imagi

关键词： Deceased donors Living donors Kidney transplantation Minimally invasive surgery Robotics

Evolutionary and paleobiological implications of Coleoptera (Insecta) from Tethyan-influenced Cretaceous ambers

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Geoscience Frontiers 2016年第4期7卷 695-706页

作者： David peris Enrico Ruzzier Vincent Perrichot Xavier Delclos Departament de Dinamica de la Terra i de l'Ocea and lnstitut de Recerca de la Biodiversitut (IRBio) Facultat de Geologia Universitat de Barcelona Marti i Franques s/n 08071 Barcelona Spain Department of Life Science Natural History Museum Cromwell Rd SW7 5BD London UK UMR CNRS 6118 Geosciences & OSUR Universite de Rennes 1 35042 Rennes cedex France

The intense study of coleopteran inclusions from Spanish （Albian in age） and French （Albian-Santonian in age） Cretaceous ambers, both of Laurasian origin, has revealed that the majority of samples belong to the Polyphaga suborder and, in contrast to the case of the compression fossils, only one family of Archostemata, one of Adephaga, and no Myxophaga suborders are represented. A total of 30 families from Spain and 16 families from France have been identified （with almost twice bioinclusions identified in Spain than in France）; 13 of these families have their most ancient representatives within these ambers. A similar study had previously only been performed on Lebanese ambers （Barremian in age and Gondwanan in origin）, recording 36 coleopteran families. Few lists of taxa were available for Myanmar （Burmese） amber （early Cenomanian in age and Laurasian in origin）. Coleopteran families found in Cretaceous ambers share with their modern relatives mainly saproxylic and detritivorous habits in the larval or adult stages, rather than wood-boring behavior. Fifteen of the coleopteran families occur in both the Lebanese and Spanish ambers; while only five are present in both Spanish and French. Considering the paleogeographic proximity and similarity of age of the Spanish and French ambers, the small number of taxa found in common at both areas is surprising. The ancient origin for the Lebanese and Spanish ambers, the paleogeography （including some barriers for terrestrial biota） and the local paleohabitats are factors that may explain the dissimilarity with the French specimens. Wildfires are believed to be a more likely cause of resin production during the Cretaceous than infestation by beetles. Current knowledge of the beetle species found in the Cretaceous ambers is introduced.

关键词： Beetle Fossil Laurasia Gondwana Resin production

Three-hundred and sixty degrees of surgical approaches to the maxillary sinus

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2022年第1期8卷 42-53页

作者： Natalia C.Rezende Carlos D.Pinheiro-Neto Luciano C.P.C.Leonel Jamie J.Van Gompel Maria peris-Celda Garret Choby Division of Rhinology and Skull Base Surgery Department of Otolaryngology-Head&Neck SurgeryMayo ClinicRochesterMinnesotaUSA Department of Neurologic Surgery Mayo ClinicRochesterMinnesotaUSA

Objectives:To demonstrate three-hundred and sixty degrees of maxillary sinus(MS)surgical approaches using cadaveric dissections,highlighting the step-by-step anatomy of each ***:Two latex-injected cadaveric specimens were utilized to perform surgical dissections to demonstrate different approaches to the *** procedures were documented with macroscopic images and endoscopic ***:Dissections were performed to approach the MS medially(endoscopic maxillary antrostomy and ethmoidectomy),anteriorly(Caldwell-Luc),superiorly(transconjunctival/transorbital approach),inferiorly(transpalatal approach),and posterolaterally(preauricular hemicoronal approach).Conclusion:A number of approaches have been described to address pathology in the *** should be familiar with indications,limitations,and surgical anatomy from different perspectives to approach the *** paper illustrates anatomic approaches to the MS with detailed step-by-step cadaveric dissections and case examples.

关键词： anatomy Caldwell-Luc dissection endoscopic sinus surgery infratemporal fossa maxillary sinus pterygopalatine fossa

Use of micellar liquid chromatography for rapid monitoring of fungicides post harvest applied to citrus wastewater

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Journal of Environmental Sciences 2016年第4期28卷 284-292页

作者： Juan peris-Vicente Ana Marzo-Mas Pasqual Roca-Genovés Samuel Carda-Broch Josep Esteve-Romero Departamento de Quimica Fisica i Analitica ESTCE Universitat Jaume I 12071 Castello Spain

A method based on micellar liquid chromatography has been developed to simultaneously monitor four pesticides largely post-harvest applied to citrus：thiabendazole,pyrimethanil,o-phenylphenol and *** samples were filtered and directly injected without other treatment,thus avoiding extraction *** composition of the mobile phase was optimized using a chemometrical approach to achieve and excellent resolution to 0.07 mol/L SDS/5%,V/V 1-pentanol buffered at p H *** phase run through a C18 column at 1 m L/min at room *** detection was performing by UV–Visible absorbance using a wavelength program：0–10 min,305 nm（for thiabendazole）;10–12;265 nm（for pyrimethanil）and 12–18,220 nm（o-phenylphenol and imazalil）.The developed method was validated following the guidelines of the US Environmental Protection Agency in terms of：quantitation range,（0.5–4 to 15μg/m L）,linearity（r2〉0.9995）,sensitivity（LOD,0.18–1.4μg/m L）,precision（〈9.2%）,trueness（93.9%–103.7%）,and ruggedness（〈9.9%）.It was found that the fungicides remain up to eight days in surface water at outdoor *** method was used to screen the presence of the analytes in several waste water samples,and was proved to be useful in routine analysis.

关键词： Direct injection Micellar Pesticide Pollution Validation Water

Hemodynamic management in brain dead donors

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World Journal of Transplantation 2021年第10期11卷 410-420页

作者： Chiara Lazzeri Manuela Bonizzoli Cristiana Guetti Giorgio Enzo Fulceri Adriano peris Intensive Care Unit and Regional ECMO Referral Centre Azienda Ospedaliero Universitaria CareggiFlorence 50134Italy

Donor management is the key in the complex donation process,since up to 20%of organs of brain death donors(DBD)are lost due to hemodynamic *** challenge is made more difficult due to the lack of strong recommendations on therapies for hemodynamic management in DBDs and more importantly to the epidemiologic changes in these donors who are becoming older and with more comorbidities(marginal donors).In the present manuscript we aimed at summarizing the available evidence on therapeutic strategies for hemodynamic management(focusing on vasoactive drugs)and monitoring(therapeutic goals).Evidence on management in elderly DBDs is also *** management continues critical care but with different and specific therapeutic goals since the number of donor goals met is related to the number of organs retrieved and *** monitoring of selected parameters(possibly including serial echocardiography)is the clinical tool able to guarantee the achievement and maintaining of therapeutic *** worldwide differences,norepinephrine is the vasoactive of choice in most countries but,whenever higher doses(>0.2 mcg/kg/min)are needed,a second vasoactive drug(vasopressin)is *** therapy(desmopressin,corticosteroid and thyroid hormone)are suggested in all DBDs independently of hemodynamic *** the single patient,therapeutic regimen(imprimis vasoactive drugs)should be chosen also according to the potential organs retrievable(*** vs liver and kidneys).

关键词： Brain-dead donors Hemodynamic Management Vasoactive drugs Hormanal therapy Echocardiography

Investigation of blood pulse PPG signal regulation on toe effect of body posture and lower limb height

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2007年第6期8卷 916-920页

作者： XIN Shang-zhi HU Sijung CRABTREE Vincent P. ZHENG Jia AZORIN-peris Vincent ECHIADIS Angelos SMITH Peter R. College of Electrical Engineering University of Shanghai for Science and Technology Shanghai 200093 China Department of Electronic and Electrical Engineering Loughborough University Leicestershire LE11 3TU UK

Objective: To study the regulation of blood pulse volume via photoplethysmography (PPG) signal detected from toe, while the lower limb is passively raised in different height positions. Methods: Use a modified non-invasive PPG technique to detect the blood pulse signal on toe with infrared (IR) photo sensor. A protocol consisting of two postures, i.e., supine and 45° reclining, was designed to conduct laboratory trial in this study. During the period of performing the protocol of these postures, the lower limb was passively raised from the heights of 10 cm to 60 cm randomly and individually with sponge blocks underneath the foot. Results: In the supine posture, the higher the foot was passively raised, the more the blood PPG signal decreased. In the 45° reclining posture, the blood PPG signal increased at the beginning and then decreased in the foot height position from 10 cm to 60 cm. In both postures the normalized AC signal changes significantly while the normalized DC signal changes little. Conclusion: The toe PPG signals can obviously indicate the regulated blood volume change with the designated postural procedures due to the heart level position.

关键词：脉搏 PPG信号调节身体姿势下肢高度趾尖效应