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Compressibility of a natural kyanite to 17.5 GPa

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Progress in Natural Science:Materials International 2009年第10期19卷 1281-1286页

作者： sean R. Shieh Michael e. Fleet Department of earth Sciences University of Western Ontario

The compressional behaviour of a natural kyanite,(Al1.99Fe0.01)SiO5,has been investigated to about 17.5 GPa at 300 K using a diamond-anvil cell and synchrotron X-ray *** pressure-volume data fitted to the third-order Birch-Murnaghan equation of state(eoS) yield an isothermal bulk modulus(K0T) of 192 ± 6 GPa and pressure derivative(K00T) of 6 ± *** K00T is fixed as 4,the derived K0T is 201 ± 2 *** values are in excellent agreement with most experimental determinations in the ***,it can be concluded that the compressibility of kyanite under high pressures has been accurately constrained.

关键词： Compressibility High-pressure Isothermal bulk modulus Kyanite Synchrotron X-ray diffraction

Characterization of Deciliation-Regeneration Process of Tetrahymena Pyriformis for Cellular Robot Fabrication

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Journal of Bionic engineering 2011年第3期8卷 273-279页

作者： Dal Hyung Kim sean e. Brigandi Paul Kim Doyoung Byun Min Jun Kim Department of Mechanical engineering & Mechanics Drexel University Philadelphia PA 19104 USA Department of Aerospace Information engineering Konkuk University Seoul 143-701 South Korea

magnetotactic Tetrahymena pyriformis GL （T. pyriformis） cells were created by the internalization of iron oxide nano particles and became controllable with a time-varying external magnetic field. Thus, T. pyriformis can be utilized as a cellular robot to conduct micro-scale tasks such as transportation and manipulation. To complete these tasks, loading inorganic or organic materials onto the cell body is essential, but functionalization of the cell membrane is obstructed by their motile organelles, cilia. Dibucaine HC1, a local anesthetic, removes the cilia from the cell body, and the functional group would be absorbed more efficiently during cilia regeneration. In this paper, we characterize the recovery of artificial magnetotactic T. pyriformis after the deciliation process to optimize a cellular robot fabrication process. After sufficient time to recover, the motility rate and the average velocity of the deciliated cells were six and ten percent lower than that of non-deciliated cells, respectively. We showed that the motile cells after recovery can still be controlled using magnetotaxis, making T. pyrfformis a good candidate to be used as a celIular robot.

关键词： Tetrahymena pyriformis deciliation cellular robot Helmholtz coil magnetic field magnetotaxis

Transaction Frequency Based Trust for e-Commerce

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Computers, Materials & Continua 2023年第3期74卷 5319-5329页

作者： Dong Huang sean Xu School of Applied Foreign Languages Zhejiang Yuexiu UniversityShaoxing312000China Anzina PTY Ltd. SydneyNSW2118Australia

Most traditional trust computing models in e-commerce do not take the transaction frequency among participating entities into consideration,which makes it easy for one party of the transaction to obtain a high trust value in a short time,and brings many disadvantages,uncertainties and even *** solve this problem,a transaction frequency based trust is proposed in this *** proposed method is composed of two *** first part is built on the classic Bayes analysis based trust modelswhich are ease of computing for the e-commerce *** second part is the transaction frequency module which can mitigate the potential insecurity caused by one participating entity gaining trust in a short *** show that the proposed method can effectively mitigate the self-promoting attacks so as to maintain the function of e-commerce system.

关键词： Transaction frequency trust Bayes analysis e-commerce

Hematologic and biochemical reference intervals for specific pathogen free 6-week-old Hampshire-Yorkshire crossbred pigs

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Journal of Animal Science and Biotechnology 2014年第3期5卷 286-290页

作者： Caitlin A Cooper Luis e Moraes James D Murray sean D Owens Department of Animal Science University of California Department of Population Health and Reproduction University of California Department of Pathology Microbiology and ImmunologySchool of Veterinary MedicineUniversity of California One Shields AvenueDavisCA 95616USA

Background： Hematologic and biochemical reference intervals depend on many factors, including age. A review of the literature highlights the lack of reference intervals for 6-wk-old specific pathogen free （SPF） Hampshire-Yorkshire crossbred pigs. For translational research, 6-wk-old pigs represent an important animal model for both human juvenile colitis and diabetes mellitus type 2 given the similarities between the porcine and human gastrointestinal maturation process. The aim of this study was to determine reference intervals for hematological and biochemical parameters in healthy 6-wk-old crossbred pigs. Blood samples were collected from 66 clinically healthy Hampshire-Yorkshire pigs. The pigs were 6 wks old, represented both sexes, and were housed in a SPF facility. Automated hematological and biochemical analysis were performed using an ADVIA 120 Hematology System and a Cobas 6000 C501 Clinical Chemistry Analyzer. Results： Reference intervals were calculated using both parametric and nonparametric methods. The mean, median, minimum, and maximum values were calculated. Conclusion： As pigs are used more frequently as medical models of human disease, having reference intervals for commonly measured hematological and biochemical parameters in 6-wk-old pigs will be useful. The reference intervals calculated in this study will aid in the diagnosis and monitoring of both naturally occurring and experimentally induced disease. In comparison to published reference intervals for older non SPF pigs, notable differences in leukocyte populations, and in levels of sodium, potassium, glucose, protein, and alkaline phosphatase were observed.

关键词： Biochemical analytes Hematology Pigs Reference interval SPF

Use of sodium bicarbonate and blood gas monitoring in diabetic ketoacidosis: A review

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World Journal of Diabetes 2018年第11期9卷 199-205页

作者： Mit P Patel Ali Ahmed Tharini Gunapalan sean e Hesselbacher Department of Internal Medicine Eastern Virginia Medical School Medicine Service Hampton Veterans Affairs Medical Center

Diabetic ketoacidosis(DKA) is a severe and toocommon complication of uncontrolled diabetes mellitus. Acidosis is one of the fundamental disruptions stemming from the disease process, the complications of which are potentially lethal. Hydration and insulin administration have been the cornerstones of DKA therapy; however, adjunctive treatments such as the use of sodium bicarbonate and protocols that include serial monitoring with blood gas analysis have been much more controversial. There is substantial literature available regarding the use of exogenous sodium bicarbonate in mild to moderately severe acidosis; the bulk of the data argue against significant benefit in important clinical outcomes and suggest possible adverse effects with the use of bicarbonate. However, there is scant data to support or refute the role of bicarbonate therapy in very severe acidosis. Arterial blood gas(ABG) assessment is an element of some treatment protocols, including society guidelines, for DKA. We review the evidence supporting these recommendations. In addition, we review the data supporting some less cumbersome tests, including venous blood gas assessment and routine chemistries. It remains unclear that measurement of blood gas pH, via arterial or venous sampling, impacts management of the patient substantially enough to warrant the testing, especially if sodium bicarbonate administration is not being considered. There are special circumstances when serial ABG monitoring and/or sodium bicarbonate infusion are necessary, which we also review. Additional studies are needed to determine the utility of these interventions in patients with severe DKA and pH less than 7.0.

关键词： Diabetic ketoacidosis Sodium bicarbonate Blood gas analysis Acidosis Ketosis Ketone bodies Hyperglycemia

electric Air Taxis Create Megadeal Buzz

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engineering 2022年第6期8卷 5-8页

作者： sean O’Neill Senior Technology Writer

Big investments and partnership announcements made 2021 a landmark year for the nascent electric vertical take-off and landing(e VTOL) aircraft industry. Indeed, several e VTOL developers have the bold-and many say wildly optimistic-ambition to achieve regulatory certification and commence carrying paying passengers as early as 2024.

关键词： Create passenger carrying

The Changing Cold Regions Network:Observation,diagnosis and prediction of environmental change in the Saskatchewan and Mackenzie River Basins,Canada

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Science China earth Sciences 2015年第1期58卷 46-60页

作者： Chris M DeBeeR Howard S WHeATeR William L QUINTON sean K CAReY Ronald e STeWART Murray D MACKAY Philip MARSH Global Institute for Water Security University of SaskatchewanNational Hydrology Research Centre Cold Regions Research Centre Wilfrid Laurier University School of Geography and earth Sciences Mc Master University Department of environment and Geography University of Manitoba Science and Technology Branch Environment Canada

Climate change is causing rapid and severe changes to many earth systems and processes,with widespread cryospheric,ecological,and hydrological impacts globally,and especially in high northern *** is of major societal concern and there is an urgent need for improved understanding and predictive tools for environmental *** Changing Cold Regions Network(CCRN)is a Canadian research consortium with a focus to integrate existing and new experimental data with modelling and remote sensing products to understand,diagnose,and predict changing land,water,and climate,and their interactions and feedbacks over the geographic domain of the Mackenzie and Saskatchewan River Basins in *** network operates a set of 14 unique and focused Water,ecosystem,Cryosphere and Climate(WeCC)observatories within this region,which provide opportunities to observe and understand processes and their interaction,as well as develop and test numerical simulation models,and provide validation data for remote sensing *** paper describes this network and its observational,experimental,and modelling *** overview of many of the recent earth system changes observed across the study region is provided,and some local insights from WeCC observatories that may partly explain regional patterns and trends are *** of the model products being developed are discussed,and linkages with the local to international user community are reviewed—In particular,the use of WeCC data towards model and remote sensing product calibration and validation is *** future activities and prospects for the network are also presented at the end of the paper.

关键词： climate change cryosphere hydrology atmospheric science ecology modelling Canada

Lymphocyte phenotypes in wild-caught rats suggest potential mechanisms underlying increased immune sensitivity in post-industrial environments

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Cellular & Molecular Immunology 2012年第2期9卷 163-174页

作者： Ashley M Trama Zoie e Holzknecht Anitra D Thomas Kuei-Ying Su sean M Lee emily e Foltz Sarah e Perkins Shu S Lin William Parker Department of Surgery Duke University Medical Center Durham NC 27710 USA Cardiff School of Biosciences Cardiff CFIO 3AX UK Department of Immunology Duke University Medical Center Durham NC 27710 USA

The immune systems of wild rats and of laboratory rats can been utilized as models of the human immune system in pre-industrial and post-industrial societies, respectively. In this study, lymphocyte phenotypes in wild rats were broadly characterized, and the results were compared to those obtained by us and by others using cells derived from various strains of laboratory rats. Although not expected, the production of regulatory T cells was not apparently different in wild rats compared to laboratory rats. On the other hand, differences in expression of markers involved in complement regulation, adhesion, signaling and maturation suggest increased complement regulation and decreased sensitivity in wild-caught rats compared to laboratory rats, and point toward complex differences between the maturation of T cells. The results potentially lend insight into the pathogenesis of post-industrial epidemics of allergy and autoimmune disease.

关键词： allergy autoimmunity biome hygiene immune regulation

A review of halide charge carriers for rocking-chair and dual-ion batteries

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Carbon energy 2021年第4期3卷 627-653页

作者： sean KSandstrom Xin Chen Xiulei Ji Department of Chemistry Oregon State UniversityCorvallisOregonUSA

This review discusses how halide ion species have been used as charge carriers in both anion rocking-chair and dual-ion battery(DIB)*** anion rocking-chair batteries based on fluoride and chloride have emerged over the past decade and are garnering increased research interest due to their large theoretical energy density values and the natural abundance of halide-containing ***,DIBs that use halide species as their anionic charge carrier are seen as one of the promising next-generation battery technologies due to their low cost and high working *** numerous polyatomic anions have been studied as charge carriers,the use of single halide ions(i.e.,F−and Cl−)and metal-based superhalides(e.g.,[MgCl_(3)]−)as anionic charge carriers in DIBs has been considerably less ***,we provide an overview of some of the key advances and recent progress that has been made with regard to halide ion charge carriers in electrochemical energy *** offer our perspectives on the current state of the field and provide a roadmap in hopes that it helps researchers toward making new advances in these promising and emerging areas.

关键词： charge carrier dual-ion battery halide rocking-chair battery superhalide