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国际医学放射学杂志 2018年第3期 373-373页

作者： Y.S.kim Y.N.Jang J.S.Song 贺思健 Department of Radiology Severance Hospital Yonsei University College of Medicine

摘要目的比较梯度回波MR弹性成像(GRE-MRE)和自旋回波-回波平面MR弹性成像(se-EPI-MRE)在肝纤维化分期中的诊断性能。方法对涉及MRE诊断肝纤维化的研究

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广泛棘波放电独立组分的分析:原发性和继发性双侧同步现象的比较

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世界核心医学期刊文摘（神经病学分册） 2005年第8期1卷 32-32页

作者： Jung K.-Y. kim J.-M. kim D.W. Chung C.-S. 江山 Department of Neurology Samsung Medical CenterSungkyunkwan Univ. Sch. of Medicine 50 Ilwon-dong Gangnam-Gu Seoul 135-710 South Korea

Objective: To differentiate between primary and secondary bilateral synchrony( PBS and SBS, respectively) in generalized spike-and-wave discharges (GSWD),we applied independent component analysis (ICA) to GSWD, and analyzed the character istic patterns of independent components. Methods: EEGs from 19 patients with GS WD (9 PBS patients, 10 SBS patients)were studied. Thirty GSWD epochs were selected and concatenated to construct an EEG datamatrix that was subjected to ICA. se lected independent components were localized by mapping them on a spherical mode l of the head by means of brain electrical source analysis (BESA) to define dipo le ***: Epileptic components of GSWD were clearly separated by the I CA algorithm in all patients. Between one and three components per patient were responsible for GSWD. In PBS patients, 70.6%of the independent components had d ipole sources within the dorsolateral frontal region, and 56.5%of the independe nt components in SBS patients were within the medial frontal region (P=0.012). T he orientation of all of the independent components in PBS patients was radial, whereas 47.8%of the independent components in SBS patients were tangential;this difference was statistically significant (P=0.001). Conclusions:Spatiotemporal decomposition of GSWD by using ICA might be helpful for differentiating SBS from PBS. Significance: The localization of the dipole sources of the independent co mponents may provide insight into the pathophysiological origins of GSWD.

关键词：棘波同步现象数据矩阵病理生理学偶极中间区域体模型特征模式衰减规律

*** tissues bank for vision health research

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Annals of Eye Science 2018年第1期 499-499页

作者： kim Santerre Mathieu Thériault Sylvain Chemtob Lucie Germain Claude Giasson Sylvain Guérin Solange Landreville Patrick JRochette Christian Rochette Mike Sapieha Élodie Boisselier Vincent Pernet Stéphanie Proulx Centre de Recherche du CHU de Québec-UniversitéLaval Axe Médecine RégénératriceQuébecQCCanada Centre de Recherche en Organogénèse Expérimentale de l'UniversitéLaval/LOEX QuébecQCCanada Département d'Ophtalmologie et d'Oto-Rhino-Laryngologie-Chirurgie Cervico-Faciale Facultéde MédecineUniversitéLavalQuébecQCCanada Département d’ophtalmologie Universitéde MontréalQCCanada Maisonneuve-Rosemont Hospital Research Center MontrealQCCanada Département de chirurgie Facultéde MédecineUniversitéLavalQuébecQCCanada École d’optométrie Universitéde MontréalQuébecQCCanada

Background:This infrastructure delivers biological material necessary for several research projects to Vision Health Research Network investigators(VHRN).Methods:Héma-Québec is the organism in charge obtaining consent and retrieving donor eyes for patient treatment or for *** Quebec City,donor eyes are sent to the eye bank of the“Centre Universitaire d’Ophtalmologie”(CUO)of Saint-Sacrement *** at the eye bank evaluate the quality of the *** unfit for graft are transferred to the infrastructure where the coordinator encodes samples prior to their ***:Between 2013 and 2017,27 fundamental investigators,clinical investigators and collaborators supported by 60 students,trainees and laboratory assistants used this infrastructure to move forward their *** 2013,results from those projects generated 21 scientific publications and 232 *** infrastructure helped VHRN investigators obtain near 4 million dollars in grants from many organisms(CIHR,NseRC,Foundations,etc.).These grants allowed recruitment and formation of highly qualified *** year(April 2016 to March 2017),189 corneas and 23 eyes transited through the ***:This infrastructure is available for all investigators that are members of the *** original projects have been elaborated thanks to the human ocular tissues provided by this *** projects will advance our knowledge in vision health.A better understanding of eye functions will lead to new treatments for eye diseases.

关键词： Human ocular tissues for research fresh tissues

人为气溶胶排放导致最近80年东亚夏季风在过去四个世纪以来空前减弱

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地球环境学报 2019年第6期10卷 527-542页

作者：刘禹蔡文炬孙长峰宋慧明 kim MCobb 李建平 Steven WLeavitt 吴立新蔡秋芳刘若时 Benjamin Ng Paolo Cherubini Ulf Büntgen 宋怡王国建雷莺晏利斌李强马永永方丛羲孙军艳李旭祥 Deliang Chen Hans WLinderholm 中国科学院地球环境研究所黄土与第四纪地质国家重点实验室西安710061 中国科学院第四纪科学与全球变化卓越创新中心西安710061 青岛海洋科学与技术试点国家实验室-海洋动力过程与气候功能实验室青岛266237 北京师范大学地球科学前沿交叉研究中心和全球变化研究联合中心北京100875 中国海洋大学物理海洋教育部重点实验室和青岛海洋科学与技术国家实验室青岛266237 CSIRO Marine and Atmospheric Research AspendaleVIC 3195Australia School of Earth and Atmospheric Sciences Georgia Institute of TechnologyAtlantaGA 30332USA The Laboratory of Tree-Ring Research The University of ArizonaTucsonAZ 85721USA 西安交通大学人居环境与建筑工程学院西安710049 Swiss Federal Institute for Forest Snow and Landscape ResearchCH-8903 BirmensdorfSwitzerland Department of Geography University of CambridgeCambridge CB23ENUK Global Change Research Centre and Masaryk University 60177 BrnoCzech Republic 陕西省气象局西安710014 Climate Group Department of Earth SciencesUniversity of GothenburgBox 100SE-40530 GothenburgSweden

亚洲夏季风(Asian Summer Monsoon,ASM)对亚洲数十亿人口的生存、亚洲生态系统和生物多样性的分布、以及农业生产(粮食安全)和工业活动影响严重。因此了解ASM过去时空变化及其动力学过程对陆地生态系统、水资源、森林和景观研究至关重... 详细信息

亚洲夏季风(Asian Summer Monsoon,ASM)对亚洲数十亿人口的生存、亚洲生态系统和生物多样性的分布、以及农业生产(粮食安全)和工业活动影响严重。因此了解ASM过去时空变化及其动力学过程对陆地生态系统、水资源、森林和景观研究至关重要。近几十年,器测记录显示以降水量为代表的ASM强度一直在减弱,但这一减弱趋势的起始时间和动力学过程尚不清楚。为此,第一次集成了ASM西部-中部边缘带10个对降水敏感的树木年轮宽度年表,重建了公元1566年以来反映ASM强度变化的降水序列。重建结果不仅捕捉到了ASM过去4个世纪以来强弱变化历史,也反映出历史上蝗灾与弱季风的关联。特别是发现了最近80年具有过去448年中前所未有的、最为强烈的、显著且持续时间最长的ASM强度减弱趋势。这一减弱趋势与在温室效应影响下ASM本该增强的预期大相庭径。耦合气候模型实验表明,北半球人为硫酸盐气溶胶排放的逐渐增加,对ASM减弱起了决定性作用。

关键词：东亚夏季风树木年轮降水重建人为气溶胶 ASM减弱趋势

粳稻“龙锦1号／香软米1578”F3家系群糙米矿质元素含量变异及相关性分析

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中国水稻科学 2008年第3期22卷 290-296页

作者：孙明茂杨昌仁李点浩崔仁守曹桂兰李圭星金弘烈于元杰李英泰韩龙植中国农业科学院作物科学研究所/国家农作物基因资源与基因改良重大科学工程/农业部作物种质资源与生物技术重点开放实验室北京100081 韩国农村振兴厅作物科学院山东农业大学农学院山东泰安271018

利用粳稻品种间杂交组合"龙锦1号/香软米1578"的196份F3家系,对糙米中Fe、se、Zn、Cu、Mn、Ca、Mg、K、Na和P等10种矿质元素含量的变异及其相关性进行了分析。10种矿质元素在F3家系间均有较大的变异,其中Na含量变异最大,Zn含量变异最小... 详细信息

利用粳稻品种间杂交组合"龙锦1号/香软米1578"的196份F3家系,对糙米中Fe、se、Zn、Cu、Mn、Ca、Mg、K、Na和P等10种矿质元素含量的变异及其相关性进行了分析。10种矿质元素在F3家系间均有较大的变异,其中Na含量变异最大,Zn含量变异最小,变异系数分别为77.69%和12.04%。各矿质元素含量的变异系数大小顺序为Na>se>Cu>Fe>Mg>Mn>Ca>P>K>Zn。不同矿质元素含量也有较大的差异,F3家系群各矿质元素含量平均值高低排序为P>K>Mg>Ca>Fe>Mn>Zn>Na>Cu>se。糙米中10种矿质元素含量在F3家系群中均表现为正态分布,为由多基因控制的数量性状。Zn与Fe、Cu,Mn与Mg、Ca、K、P,Ca与Mg、K、Na、P,Mg与K、P,P与K、Na含量呈显著或极显著正相关,而Fe与se、Mn与Na、Mg与Na含量呈显著或极显著负相关。Mn、Ca、Mg、K、P含量与其他矿质元素含量间的相关关系较Fe、se、Cu、Zn含量与其他矿质元素含量间的相关关系更为密切。

关键词：水稻矿质元素家系遗传变异相关性

比较钆塞酸二钠注射前后基于自旋回波平面回波成像和梯度回波成像的3 TMR弹性成像

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国际医学放射学杂志 2017年第6期 741-741页

作者： Y.S.kim J.S.Song S.Kannengiesser S.Y.seo 张毓婧 Department of Radiology Chonbuk National University Medical School and Hospital

摘要目的有无钆塞酸二钠注射情况下,比较基于自旋回波平面回波成像(se-EPI)和梯度回波成像(GRE)的3 T MR弹性成像(MRE)。方法共纳入84例病人,均行钆塞酸二

关键词：自旋回波钆塞酸二钠弹性成像平面回波成像 TMR

婴儿时期成功进行升主动脉缩窄成形术后其幼儿期的升主动脉弹性

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世界核心医学期刊文摘（心脏病学分册） 2005年第4期1卷 51-51页

作者： kim G. B. Kang S. J. Bae E. J. C. I. Noh 任付先 Department of Pediatrics Se oul Natl. Univ. Children's Hosp. 28 Yongondong Chongno-gu 110-744 Seoul South Korea

Background: Based on the hypothesis that vascular dysfunction in the ascending aorta can cause morbidity, we undertook this study on the elastic properties of ascending aorta and left ventricular(LV) function in young children who receive d coarctoplasty in early infancy. Methods: Blood pressures(BP) in the right arm and ascending aortic internal diameters determined by M-mode ultrasound at rest and after exercise were measured in 25 patients(mean age, 6.4±3 years) and 22 control subjects(mean age, 5.8±2.4 years). Ascending aortic stiffness index and distensibility were calculated using BP measurements and ascending aortic inter nal diameters. In addition, LV parameters(systolic and diastolic function, mass index) were evaluated. Results: Compared with control subjects, patients had inc reased stiffness index(at rest: 4.87±1.94 versus 3.57±1.19, P=0.021; after exe rcise: 4.33±1.91 versus 3.2±1.26, P=0.034) and decreased distensibility(at res t: 6.90±3.15 versus 8.72±2.77, P=0.02; after exercise: 5.69±2.39 versus 7.88 ±3.44 cm2 dyn-1 10 -6, P=0.023). BP and LV parameters showed no consistent di fferences between the two groups. In patients, distensibility was significantly correlated with systolic BP(at rest: P=0.008; after exercise: P=0.014) and pulse pressure(at rest: P=0.013; after exercise: P=0.001). Conclusions: This study su ggests that vasculopathy of ascending aorta is possible in some young children d espite early correction. However, long-term tracking study is needed to clarify the significance of the study.

关键词：升主动脉缩窄婴儿时期主动脉内径硬度指数主动脉血管功能失常右上臂婴儿早期超声测量重量指数

膝关节退变:同向性3D Fse、同向性3D平衡快速视野回波(FFE)和传统2D Fse MR影像对比

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国际医学放射学杂志 2013年第6期 575-575页

作者： J.Y.Jung Y.C.Yoon H.R.kim B.K.Choe J.H.Wang J.Y.Jung 陶应伟 Department of Radiology Dongtan Sacred Heart Hospital Hallym University Hwaseong Gyeonggi-doKorea

摘要目的使用3.0 T MR序列——人工同向性3D中间加权(IW)快速自旋回波(se)、同向性3D平衡快速视野回波(FFE)和传统的2D Fse评估有症状病人的膝关节关节软

关键词：同向性 FFE Fse MR Fse 回波视野