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Exploring the effects of coronary artery disease as a preexisting comorbidity on mortality in hospitalized septic patients:a retrospective observation study

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Emergency and Critical Care Medicine 2024年第2期4卷 47-51页

作者： Anmol Multani Greg Stahl Kerry Johnson scott Goade robert D.Arnce College of Osteopathic Medicine Kansas City UniversityJoplinMOUSA Department of Data Improvement Freeman Health SystemJoplinMOUSA Department of Mathematics Missouri Southern State UniversityJoplinMOUSA Department of Pharmacy Freeman Health SystemJoplinMOUSA

Background:Sepsis has high prevalence and mortality rate,and it is imperative to identify populations at risk of poor sepsis *** patients with preexisting chronic comorbidities are shown to have worse sepsis *** identifying comorbidities with greater influence on sepsis progression,we can direct limited resources to septic patients with comorbidities and reduce health care *** comorbidities can impact the risk of developing sepsis and having worse *** artery disease(CAD)is a common comorbidity,especially in the elderly,and a leading cause of death *** wished to investigate the influence of CAD as a comorbidity on sepsis and hypothesized that preexisting CAD would increase mortality in hospitalized septic ***:We conducted retrospective observational study using patient data from Freeman Health System in Joplin,*** analyzed patient records from Freeman Health System database from January 1,2019,to June 30,*** patients were identified using the International Classification of Diseases,Tenth revision sepsis *** identify septic patients with preexisting CAD,we used International Classification of Diseases,Tenth revision codes for *** compared mortality rates for septic patients with and without ***:Two-sample proportion test was conducted to test the difference in mortality between septic patients with and without preexisting *** difference in mortality for the total population was−0.016(P=0.553).In the male and female subgroups,the differences in mortality were 0.0122(P=0.739)and−0.0511(P=0.208),*** differences in mortality in patients aged 40 to 64 years and 65 years and older were−0.0077(P=0.870)and 0.0007(P=0.983),*** statistical tests failed to find significant differences when comparing septic patients with and without preexisting *** was no significant difference in the age and sex ***:Our study showed that CAD alone was n

关键词： Comorbidity Coronary artery disease Inflammation Mortality rate in sepsis prognosis Sepsis

Digital Art as Urban Communication

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国际大都市发展研究（中英文） 2024年第1期 86-89,76,77页

作者： scott McQuire School of Culture and Communication University of MelbourneVIC 3010Australia

As mobility and migration become the norm,citizens in modern cities live among people who remain strangers to each *** creates new opportunities and challenges for urban social *** space is a critical forum in which strangers encounter each other and have the opportunity to develop social protocols for coexisting in *** media technologies have huge impact on the form and quality of public *** art can create experimental public spaces in which mediated connections and embodied presence are combined in new *** the practice and research of digital art,we can imagine a communicative city in which urban digital media is less about spectacle,and more about promoting new forms of public speech and social encounter between people.

关键词： Urban communication Digital art Public space Geomedia

Habitat selection and dispersal: individual decision rules

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Habitat selection and dispersal: individual decision rules

Manipulation of photosensory and circadian signaling restricts phenotypic plasticity in response to changing environmental conditions in Arabidopsis

23rd International Ornithological Congress

作者： Charles r.brown scott K.robinson Dept. of Biological Sciences Univ. of Tulsa Tulsa Oklahoma 74104 USA Dept. of Animal Biology Univ. of Illinois at Urbana-Champaign Urbana Illinois 61801 USA

＜正＞ recent research has demonstrated the existence of generalized decision rules used by a variety of birds in choosing breeding habitat. These processes fall broadly into two classes: those based on how an individual itself performs during reproduction and those based on its assessment of how other individuals of the same species perform. The former includes cases in which birds base breeding dispersal and subsequent settlement decisions on the relative success of their own current or past nesting attempt. The latter includes cases in which

关键词： decision rules dispersal group living habitat selection reproductive success

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Molecular Plant 2024年第9期17卷 1458-1471页

作者： Martin William Battle scott Fraser Ewing Cathryn Dickson Joseph Obaje Kristen N.Edgeworth rebecca Bindbeutel rea LAntoniou-Kourounioti Dmitri A.Nusinow Matthew Alan Jones Plant Science Group School of Molecular BiosciencesUniversity of GlasgowGlasgow G128QQUK Danforth Plant Science Center St.LouisMO 63132USA Department of Biological and Biomedical Sciences Washington University in St.LouisSt.LouisMO 63130USA Present address:School of Biological and Environmental Sciences Liverpool John Moores UniversityLiverpool L22QPUK

Plants exploit phenotypic plasticity to adapt their growth and development to prevailing environmental *** of light and temperature signals is aided by the circadian system,which provides a temporal *** plasticity provides a selective and competitive advantage in nature but is obstructive during large-scale,intensive agricultural practices since economically important traits(including vegetative growth and flowering time)can vary widely depending on local environmental *** prevents accurate prediction of harvesting times and produces a variable *** this study,we sought to restrict phenotypic plasticity and circadian regulation by manipulating signaling systems that govern plants'responses to environmental *** modeling of plant growth and develop-ment predicted reduced plant responses to changing environments when circadian and light signaling pathways were *** tested this prediction by utilizing a constitutively active allele of the plant photoreceptor phytochrome B,along with disruption of the circadian systemvia mutation of *** found that these manipulations produced plants that are less responsive to light and temper-ature cues and thus fail to anticipate *** engineered plants have uniform vegetative growth and flowering time,demonstrating how phenotypic plasticity can be limited while maintaining plant *** has significant implications for future agriculture in both open fields and controlled environments.

关键词： circadian developmental plasticity phenotypic plasticity external coincidence light temperature

robotic-assisted retroperitoneal lymph node dissection for stage II testicular cancer

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Asian Journal of Urology 2024年第1期11卷 121-127页

作者： George McClintock Ahmed S.Goolam Don Perera ryan Downey scott Leslie Peter Grimison Henry Woo Peter Ferguson Nariman Ahmadi Department of Urology Chris O'Brien LifehouseSydneyNSWAustralia Department of Anaesthesia Chris O'Brien LifehouseSydneyNSWAustralia The University of Sydney SydneyNSW2006Australia Department of Medical Oncology Chris O'Brien LifehouseSydneyNSWAustralia

Objective:To evaluate the perioperative as well as early oncological outcomes of patients undergoing robotic retroperitoneal lymph node dissection for treatment of testicular ***:We conducted a prospective consecutive case series of patients undergoing robotic assisted retroperitoneal lymph node dissection for metastatic testicular cancer between May 2018 and July 2021 at our *** were collected on patient and tumour characteristics,intraoperative and postoperative parameters,and functional and oncological *** statistics are ***:Nineteen patients were identified;18(94.7%)completed the procedure robotically and one was converted to open surgery;78.9%of patients had stage≥IIB and 12(63.2%)patients had undergone prior *** median operative time was 300(interquartile range[IQr]240-315)*** blood loss was 100(IQr 50-175)*** length of stay was 2(range 1-11)*** robotically completed patients commenced diet and passed flatus on Day 1 and were discharged by Day *** median lymph node yield was 40.5(IQr 38-51)*** patients undergoing nerve-sparing procedures recovered antegrade ejaculatory *** patient had a Clavien-Dindo III complication(chylous ascites requiring drainage).At a median follow-up of 22.3(IQr 16.3-24.9)months,one patient developed retroperitoneal recurrence,which was successfully treated with second-line chemotherapy;no other patients have had ***:robotic retroperitoneal lymph node dissection is a safe and feasible alternative to open surgery in appropriately selected patients,offering low *** oncological outcomes are *** cohorts and longer follow-ups are required to validate our institution's findings.

关键词： retroperitoneal lymph node dissection robotic surgery Testicular cancer retroperitoneal node dissection

High association strengths are linked to phenotypic similarity,including plumage color and patterns,of participants in mixed-species bird flocks of southwestern China

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Current Zoology 2024年第1期70卷 34-44页

作者： Liping Zhou Christos Mammides Youfang Chen Wenyi Zhou Wenzhang Dai Edward L.Braun rebecca T.Kimball Yang Liu scott K.robinson Eben Goodale Guangxi Key Laboratory of Forest Ecology and Conservation College of ForestryGuangxi UniversityNanning 530004China Kunming Natural History Museum of Zoology Kunming Institute of ZoologyChinese Academy of SciencesKunming 650223China Nature Conservation Unit Frederick University7Yianni Frederickou StreetPallouriotissaNicosia 1036Cyprus State Key Laboratory of Vegetation and Environmental Change Institute of BotanyChinese Academy of SciencesBeijing 100093China Florida Museum of Natural History University of FloridaGainesvilleFL 34201USA Department of Biology University of FloridaGainesvilleFL 34201USA School of Life Science and Institute of Wetland Ecology Nanjing UniversityNanjing 210000China State Key Laboratory of Biocontrol School of EcologySun-Yatsen UniversityGuangzhou 510275China Department of Health and Environmental Science Xi'an Jiaotong Liverpool UniversitySuzhou 215123China

Participants in mixed-species bird flocks(MSFs)have been shown to associate with species that are similar in body size,diet,and evolutionary history,suggesting that facilitation structures these *** addition,several studies have suggested that species in MsFs resemble each other in their plumage,but this question has not been systematically investigated for any MsF *** the nonbreeding season of 2020 and 2021,we sampled 585 MSFs on 14 transects in 2 habitats of Tongbiguang Nature reserve in western Yunnan Province,*** performed social network analysis and the Multiple regression Quadratic Assignment Procedure to evaluate the effect of 4 species traits(body size,overall plumage color,distinctive plumage patterns,and diet)and evolutionary history on species association strength at the whole-MSF and within-MSF *** 41 significant relationships showed that species with stronger associations were more similar in their various *** size had the strongest effect on association strength,followed by phylogeny,plumage patterns,and plumage color;diet had the weakest *** results are consistent with the hypotheses that the benefits of associating with phenotypically similar species outweigh the potential costs of interspecific competition,and that trait matching can occur in plumage characteristics,albeit more weakly than in other *** explanations exist as to why similarities in plumage may occur in MSFs,including that they could reduce predators'ability to target phenotypically"odd"*** trait matching in plumage occurs through assortative processes in ecological time or is influenced by co-evolution requires furtherstudy.

关键词： co-evolution interaction networks mixed-species animal groups phenotypic similarity trait convergence

Can a Teacher Salary Increase Promote Students' Educational Performance?

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China & World Economy 2024年第4期32卷 114-145页

作者： Tianyang Liu Baozhong Su Jingjing Wang scott rozelle College of Economics and Management China Agricultural UniversityChina College of Agricultural Economics and Management Shanxi Agricultural UniversityChina Stanford Center on China's Economy and Institutions Stanford UniversityUSA

Policymakers in China have attempted to improve the quality of rural education by investing in teacher salaries through initiatives like the rural Teachers Support Plan(rTSP).This study estimates the efects of teacher salary increase on students'educational outcomes in rural China by utilizing the exogenous variations of rural teacher salaries induced by the *** employs an intensity-based difference-in-differences strategy and panel data from 2010 to 2018 with 3,351 rural *** findings reveal that an increase in teacher salaries had a significant positive impact on students'examination *** the results of mechanism analysis indicate that salary increases could have both quality and quantity effects on students'outcomes by increasing the proportion of highly educated teachers and reducing the student-teacher *** findings contribute to the discussion on the importance of teacher salary incentives in education production functions and provide insights for other countries undertaking rural education reforms.

关键词： educational performance rural children rural Teachers Support Plan teache salary

APIr:Aggregating Universal Proteomics Database Search Algorithms for Peptide Identification with FDr Control

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Genomics, Proteomics & Bioinformatics 2024年第2期22卷 171-187页

作者： Yiling Elaine Chen Xinzhou Ge Kyla Woyshner MeiLu McDermott Antigoni Manousopoulou scott B.Ficarro Jarrod A.Marto Kexin Li Leo David Wang Jingyi Jessica Li Department of Statistics and Data Science University of CaliforniaLos AngelesCA 90095USA Department of Immuno-Oncology Beckman Research InstituteCity of Hope National Medical CenterDuarteCA 91010USA Department of Quantitative and Computational Biology University of Southern CaliforniaLos AngelesCA 90089USA Department of Cancer Biology and Blais Proteomics Center Dana-Farber Cancer InstituteDepartment of PathologyBrigham and Women’s Hospital and Harvard Medical SchoolBostonMA 02215USA Department of Pediatrics City of Hope National Medical CenterDuarteCA 91010USA Bioinformatics Interdepartmental Program University of CaliforniaLos AngelesCA 90095USA Department of Human Genetics University of CaliforniaLos AngelesCA 90095USA Department of Computational Medicine University of CaliforniaLos AngelesCA 90095USA Department of Biostatistics University of CaliforniaLos AngelesCA 90095USA

Advances in mass spectrometry(MS)have enabled high-throughput analysis of proteomes in biological *** state-of-the-art MS data analysis relies on database search algorithms to quantify proteins by identifying peptide–spectrum matches(PSMs),which convert mass spectra to peptide *** database search algorithms use distinct search strategies and thus may identify unique ***,no existing approaches can aggregate all user-specified database search algorithms with a guaranteed increase in the number of identified peptides and a control on the false discovery rate(FDr).To fill in this gap,we proposed a statistical framework,Aggregation of Peptide Identification results(APIr),that is universally compatible with all database search ***,under an FDr threshold,APIr is guaranteed to identify at least as many,if not more,peptides as individual database search algorithms *** of APIr on a complex proteomics standard dataset showed that APIr outpowers individual database search algorithms and empirically controls the *** data studies showed that APIr can identify disease-related proteins and post-translational modifications missed by some individual database search *** APIr framework is easily extendable to aggregating discoveries made by multiple algorithms in other high-throughput biomedical data analysis,e.g.,differential gene expression analysis on rNA sequencing *** APIr r package is available at https://***/yiling0210/APIr.

关键词： Shotgun proteomics Peptide–spectrum match Peptide identification Aggregation of lists FDr control

Scoping out the future:The application of artificial intelligence to gastrointestinal endoscopy

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World Journal of Gastrointestinal Oncology 2022年第5期14卷 989-1001页

作者： scott B Minchenberg Trent Walradt Jeremy r Glissen brown Department of Internal Medicine Beth Israel Deaconess Medical CenterBostonMA 02130United States Division of Gastroenterology Beth Israel Deaconess Medical CenterBostonMA 02130United States

Artificial intelligence(AI)is a quickly expanding field in gastrointestinal *** there are a myriad of applications of AI ranging from identification of bleeding to predicting outcomes in patients with inflammatory bowel disease,a great deal of research has focused on the identification and classification of gastrointestinal *** of the initial randomized,prospective trials utilizing AI in clinical medicine have centered on polyp detection during screening *** addition to work focused on colorectal cancer,AI systems have also been applied to gastric,esophageal,pancreatic,and liver *** promising results in initial studies,the generalizability of most of these AI systems have not yet been *** this article we review recent developments in the field of AI applied to gastrointestinal oncology.

关键词： Artificial intelligence Oncology Gastroenterology Endoscopy Machine learning Computer-assisted decision making Computer-aided detection Computer-aided diagnosis