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Promoting public he.lth through the.2024 Compe.dium of Physical Activitie.:Strate.ie. for adults,olde. adults,and whe.lchair use.s

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Journal of Sport and He.lth Scie.ce 2024年第6期13卷 739-742页

作者： Ste.he. D.He.rmann scott A.Conge. e.ik A.Willis Barbara e.Ainsworth Kansas Ce.te. for Me.abolism and Obe.ity Re.e.rch University of Kansas Medical CenterKansas CityKS 66160USA Division of Physical Activity and We.ght Manage.e.t Department of Internal MedicineUniversity of Kansas Medical CenterKansas CityKS 66160USA De.artme.t of Kine.iology Boise State UniversityBoiseID 83725USA Pre.e.tion Re.e.rch Ce.te. University of North Carolina at Chapel HillChapel HillNC 27599USA Colle.e.of He.lth Solutions Arizona State UniversityPhoenixAZ 85003USA School of e.e.cise.and He.lth Shanghai University of SportShanghai 200438China

Physical activity(PA)is fundame.tally linke. to public he.lth,^(1)providing be.e.its including chronic dise.se.pre.e.tion and tre.tme.t,^(2)me.tal he.lth,^(3)musculoske.e.al he.lth,^(4)and he.lthy aging,^(5)along with socioe.onomic advantage..^(6)The.e.be.e.its highlight the.importance.of promoting PA for all *** re.e.t publication of the.Compe.dium of Physical Activitie.(Compe.dium)se.ve. as a valuable.re.ource.^(7)offe.ing an update. and e.pande. guide.for adults(age. 19-59)with tailore. e.e.gy cost value. for dive.se.populations.

关键词： Activitie. pre.e.tion offe.ing

Re.timate.Re.ove.y e.timation Tool for Re.ilie.ce.Planning

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Journal of Safe.y Scie.ce.and Re.ilie.ce 2024年第1期5卷 47-63页

作者： scott Mile. Me.an Ly Nick Te.ry Youngjun Choe De.artme.t of Human Ce.te.e. De.ign&e.gine.ring Campus Box 352315University of WashingtonSeattleWA 98195United States of America De.artme.t of Industrial&Syste.s e.gine.ring Box 352650University of WashingtonSeattleWA 98195United States of America

The.*** Institute.of Standards and Te.hnology(NIST)publishe. the.Community Re.ilie.ce.Planning Guide.in *** NIST Guide.advocate. for a participatory proce.s for de.e.oping a pe.formance.me.sure.e.t frame.ork for the.jurisdiction’s re.ilie.ce.against a sce.ario *** frame.ork ce.te.s around table. of e.pe.te. and de.ire. re.ove.y time. for se.e.te. community asse.s,such as e.e.tricity,wate.,and natural gas *** NIST Guide.doe. not provide.a me.hod for e.timating the.e.pe.te. re.ove.y ***,building high-fide.ity compute. mode.s for such e.timations re.uire. substantial re.ource. that e.e. large. ju-risdictions cannot *** most promising approach to re.ove.y time.e.timation is to syste.atically use.data e.icite. from pe.ple.to tap into the.wisdom of the.knowle.ge.ble.*** pape. de.cribe. a nove. re.e.rch-through-de.ign proje.t to e.able.the.compute.-supporte. e.icitation of re.ove.y time.se.ie. *** work is the.first in the.lite.ature.to e.amine.pe.ple.s ability to e.timate.re.ove.y curve. and how de.ign in-flue.ce. such *** main contribution to re.ilie.ce.planning is thre.-fold:de.e.opme.t of a ne. e.icitation tool calle. Re.timate.unde.standing its pote.tial use. base.and providing insights into how it can facilitate.re.ilie.ce.*** is the.first tool to e.able.e.ide.ce.base. e.pe.t e.icitation in any community with limite. re.ource. for re.ilie.ce.*** re.ilie.ce.planning,those.who facilitate.high-stake. planning activitie. unde. large.unce.taintie.(e.g.,mission-critical syste. de.ign and planning)will be.e.it from a similar re.e.rch-through-de.ign proce.s.

关键词： e.pe.t e.icitation disaste. natural hazard infrastructure community re.ilie.ce re.toration use.-ce.te.e. de.ign compute.-supporte. coope.ative.work

Forge.AHe.D with stricte. crite.ia in future.trials of e.bolic stroke.of unde.e.mine. source

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Ne.ral Re.e.e.ation Re.e.rch 2022年第5期17卷 1009-1010页

作者： David Z.Rose.scott e.kasner De.artme.t of Ne.rology Morsani College of MedicineUniversity of South FloridaTampaFLUSA De.artme.t of Ne.rology Perelman School of MedicineUniversity of PennsylvaniaPhiladelphiaPAUSA

What lurks within the.crypt?With more.than 200 known cause. of is che.ic stroke.Save.,2016),what should be.the.minimum work up?Many ce.te.s offe. high-re.olution brain imaging and ve.se. studie.,te.e.e.ry monitoring f... 详细信息

关键词： strict thoracic ce.te.s

HI in High Gas-phase.Me.allicity Dwarf Galaxy WISe. J230615.06+143927.9

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Re.e.rch in Astronomy and Astrophysics 2024年第1期24卷 292-299页

作者： Yan Guo C.Se.gupta T.C.scott P.Lagos Y.Luo Purple.Mountain Obse.vatory Chinese Academy of SciencesNanjing 210023China School of Astronomy and Space.Scie.ce. University of Science and Technology of ChinaHefei 230026China Institute.of Astrophysics and Space.Scie.ce.(IA Porto) Rua das Estrelas4150-762PortoPortugal

We.pre.e.t re.olve. Giant Me.re.ave.Radio Te.e.cope.H I obse.vations of the.high gas-phase.me.allicity dwarf galaxy WISe. J230615.06+143927.9(z = 0.005)(he.e.fte. J2306) and inve.tigate.whe.he. it could be.a Tidal Dwarf Galaxy(TDG) candidate. TDGs are.obse.ve. to have.highe. me.allicitie. than normal dwarfs. J2306 has an unusual combination of a blue.g-r color of 0.23 mag, irre.ular optical morphology and high-me.allicity(12 +log(O/H) = 8.68 ± 0.14), making it an inte.e.ting galaxy to study in more.de.ail. We.find J2306 to be.an H I rich galaxy with a large.e.te.de., unpe.turbe. rotating H I disk. Using our H I data we.e.timate. its dynamical mass and found the.galaxy to be.dark matte.(DM) dominate. within its H I radius. The.quantity of DM, infe.re. from its dynamical mass, appe.rs to rule.out J2306 as an e.olve. TDG. A wide.are. e.vironme.t se.rch re.e.ls J2306 to be.isolate. from any large. galaxie. which could have.be.n the.source.of its high gas me.allicity. Additionally, the.H I morphology and kine.atics of the.galaxy show no indication of a re.e.t me.ge. to e.plain the.*** de.aile. optical spe.troscopic obse.vations of J2306 might provide.an answe. to how a se.mingly ordinary irre.ular dwarf galaxy achie.e. such a high le.e. of me.al e.richme.t.

关键词： galaxie.:abundance. galaxie.:dwarf galaxie.:irre.ular radio line.:galaxie. radio line.:ISM

Olde. Adult Compe.dium of Physical Activitie.:e.e.gy costs of human activitie. in adults age. 60 and olde.

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Journal of Sport and He.lth Scie.ce 2024年第1期13卷 13-17,F0003页

作者： e.ik A.Willis Ste.he. D.He.rmann Mary Haste.t Che.se. L.Kracht Tiago V.Barre.ra John M.Schuna Jr. Zhe.ghua Cai Minghui Quan scott A.Conge. We.dy J.Brown Barbara e.Ainsworth Ce.te. for He.lth Promotion and Dise.se.Pre.e.tion University of North Carolina at Chapel HillChapel HillNC 27599USA Kansas Ce.te. for Me.abolism and Obe.ity Re.e.rch The University of Kansas Medical CenterKansas CityKS 66160USA Division of Physical Activity and We.ght Manage.e.t Department of Internal MedicineUniversity of Kansas Medical CenterKansas CityKS 66160USA Clinical Scie.ce.Division Pennington Biomedical Research CenterBaton RougeLA 70808USA e.e.cise.Scie.ce.De.artme.t Syracuse UniversitySyracuseNY 13244USA School of e.e.cise.Sport Scie.ce Oregon State UniversityCorvallisOR 97331USA School of e.e.cise.and He.lth Shanghai University of SportShanghai 200438China De.artme.t of Kine.iology Boise State UniversityBoiseID 83725USA School of Human Move.e.t and Nutrition Scie.ce. The University of QueenslandSt.LuciaQLD 4072Australia Faculty of He.lth Scie.ce. and Me.icine Bond UniversityGold CoastQLD 4229Australia Colle.e.of He.lth Solutions Arizona State UniversityPhoenixAZ 85003USA

Purpose.To de.cribe.the.de.e.opme.t of a Compe.dium for e.timating the.e.e.gy costs of activitie. in adults>60 ye.rs(OA Compe.dium).Me.hods:Physical activitie.(PAs)and the.r me.abolic e.uivale.t of task(Me.)value. we.e.obtaine. from a syste.atic se.rch of studie. publishe. in 4 sport and e.e.cise.database.(PubMe.,e.base.SPORTDiscus(e.SCOhost),and Scopus)and a re.ie. of article. include. in the.2011 Adult Compe.dium that me.sure. PA in olde. *** value. we.e.compute. as the.oxyge. cost(VO_(2),mL/kg/min)during PA divide. by 2.7 m L/kg/min(Me._(60+))to account for the.lowe. re.ting me.abolic rate.in olde. ***:We.ide.tifie. 68 article. and e.tracte. e.e.gy e.pe.diture.data on 427 *** the.e.we.de.ive. 99 unique.Spe.ific Activity code. with corre.ponding Me._(60+)value. for olde. *** de.e.ope. a we.site.to pre.e.t the.OA Compe.dium Me._(60+)value.:https://***:The.OA Compe.dium use. data colle.te. from adults>60 ye.rs for more.accurate.e.timation of the.e.e.gy cost of PAs in olde. *** is an acce.sible.re.ource.that will allow re.e.rche.s,e.ucators,and practitione.s to find Me._(60+)value. for olde. adults for use.in PA re.e.rch and practice.

关键词： e.e.gy e.pe.diture e.e.cise Me. Olde. adults

e.H2 inhibitors promote.β-like.ce.l re.e.e.ation in young and adult type.1 diabe.e. donors

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Signal Transduction and Targe.e. The.apy 2024年第2期9卷 679-692页

作者： Ke.th Al-Hasani Safiya Naina Marikar Harikrishnan Kaipananickal scott Maxwe.l Jun Okabe.Ishant Khurana Thomas Karagiannis Julia J.Liang Lina Mariana Thomas Loudovaris Thomas Kay Assam e.-Osta e.ige.e.ics in Human He.lth and Dise.se.Program Baker Heart and Diabetes Institute75 Commercial RoadMelbourne 3004 VICAustralia De.artme.t of Diabe.e. Central Clinical SchoolMonash UniversityMelbourne 3004 VICAustralia e.ige.e.ics in Human He.lth and Dise.se.Laboratory Central Clinical SchoolMonash UniversityMelbourne 3004 VICAustralia School of Scie.ce STEM CollegeRMIT UniversityMelbourne 3001 VICAustralia Immunology and Diabe.e. Unit St Vincent’s Institute of Medical ResearchFitzroy 3065 VICAustralia De.artme.t of Me.icine.and The.ape.tics The Chinese University of Hong KongSha TinHong Kong SAR Hong Kong Institute.of Diabe.e. and Obe.ity Prince of Wales HospitalThe Chinese University of Hong Kong3/F Lui Che Woo Clinical Sciences Building30-32-Ngan Shing StreetSha TinHong Kong SAR Li Ka Shing Institute.of He.lth Scie.ce. The Chinese University of Hong KongSha TinHong Kong SAR Biome.ical Laboratory Scie.ce Department of TechnologyFaculty of HealthUniversity College CopenhagenCopenhagenDenmark

β-ce.ls are.a type.of e.docrine.ce.l found in pancre.tic isle.s that synthe.ize.store.and re.e.se.*** type.1 diabe.e.(T1D),T-ce.ls of the.immune.syste. se.e.tive.y de.troy the.insulin-producingβ-*** of the.e.ce.ls le.ds to a life.ong de.e.de.ce.on e.oge.ous insulin administration for ***,the.e.is an urge.t ne.d to ide.tify nove. the.apie. that stimulate.-ce.l growth and induce.-ce.l *** and othe.s have.shown that pancre.tic ductal proge.itor ce.ls are.a promising source.for re.e.e.atingβ-ce.ls for T1D owing to the.r inhe.e.t diffe.e.tiation *** transcriptional suppre.sion is re.ractory to e.ocrine.re.ction and tightly controls the.re.e.e.ative.pote.tial by the.e.H2 *** the.pre.e.t study,we.show that transie.t stimulation of e.ocrine.ce.ls,de.ive. from juve.ile.and adult T1D donors to the.FDAapprove. e.H2 inhibitors GSK126 and Taze.e.ostat(Taz)influe.ce.a phe.otypic shift towards aβ-like.ce.l *** transition from re.re.se. to pe.missive.chromatin state. are.de.e.de.t on bivale.t H3K27me. and H3K4me. chromatin *** e.H2 is fundame.tal toβ-ce.l re.e.e.ative.*** pancre.tic ductal ce.ls e.hibit insulin production and se.re.ion in re.ponse.to a physiological glucose.challe.ge.e. *** pre.clinical studie. unde.score.the.pote.tial of small mole.ule.inhibitors as nove. modulators of ductal proge.itor diffe.e.tiation and a promising ne. approach for the.re.toration ofβ-like.ce.l function.

关键词： e.H2 struction inhibitors

A Comparative.Study of the.L2 Pragmatic Compe.e.ce.of Unive.sity Stude.ts in Hong Kong and the.Chine.e.Mainland:The.Contributions of Sociocultural Conte.t and Linguistic Proficie.cy

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Chine.e.Journal of Applie. Linguistics 2024年第3期47卷 371-392,524页

作者： scott AUBRe. Rod e.LIS Faculty of e.ucation Chinese University of Hong Kong School of e.ucation Curtin UniversityAustralia

This study inve.tigate. the.diffe.e.ce. in pragmatic compe.e.ce.be.we.n Hong Kong and Chine.e.mainland unive.sity *** include. 19 native.spe.ke.s of e.glish,115 Chine.e.mainland stude.ts,divide. into those.who had spe.t time.abroad in an e.glish-spe.king country(CM A)and those.who had not(CM NA),and 97 Hong Kong stude.ts,divide. into those.from an e.glish-me.ium se.ondary school(Hong Kong e.I)and those.from a Chine.e.me.ium school(Hong Kong CMI).Linguistic proficie.cy was me.sure. by a C-te.t,and pragmatic compe.e.ce.by a Me.apragmatic Knowle.ge.Te.t,an Irony Te.t and a Monologic Role.*** score. we.e.compare. using ANCOVAs to control for diffe.e.ce. in *** re.ults point to a continuum of pragmatic compe.e.ce.e.I>CMI>CM A>CM NA—re.le.ting the.groups’acce.s to e.glish in re.l-life.*** diffe.e.ce. be.we.n the.Hong Kong groups and the.Chine.e.mainland groups we.e.cle.re.t in those.te.ts me.suring proce.sing capacity(i.e.,Irony Re.ponse.Time.and the.Monologic Role.Play).CM A,but not CM NA,pe.forme. as we.l as the.Hong Kong groups on me.sure. of me.apragmatic *** re.ults are.discusse. in te.ms of Bialystok’s(1993)distinction be.we.n analyze. re.re.e.tation and control of proce.sing.

关键词： pragmatic compe.e.ce social conte.t Hong Kong the.Chine.e.mainland me.apragmatic knowle.ge proce.sing capacity

卒中或短暂性脑缺血发作患者的卒中预防指南美国心脏协会／美国卒中协会为医疗卫生专业人员制定的指南

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国际脑血管病杂志 2011年第1期19卷 1-49页

作者： Kare. L. Furie.scott e. kasner Robe.t J. Adams Gre.ory W. Albe.s Ruth L. Bush Susan C. Fagan Jonathan L. Halpe.in S. Claiborne.Johnston Ire.e.Katzan Walte. N. Ke.nan Pame.a H. Mitche.l Bruce.Ovbiage.e.Yuko Y. Pale.ch Ralph L. Sacco Le. H. Schwamm Sylvia Wasse.the.l-Smolle. Tanya N. Turan De.dre.We.tworth 李海峰(译) 刘涛(译) 杨潘(译) 王鹏(译) 美国心脏协会卒中委员会心血管护理委员会临床心脏病学委员会医疗质量和转归研究跨学科委员会青岛大学医学院附属医院神经内科 266003

本指南旨在为缺血性卒中或短暂性脑缺血发作存活患者的卒中预防提供全面和及时的循证推荐，包括危险因素的控制、动脉粥样硬化性疾病的于预、心源性栓塞的抗栓治疗以及非心源性栓塞性卒中的抗血小板治疗。另外，还对其他许多特殊情况下... 详细信息

本指南旨在为缺血性卒中或短暂性脑缺血发作存活患者的卒中预防提供全面和及时的循证推荐，包括危险因素的控制、动脉粥样硬化性疾病的于预、心源性栓塞的抗栓治疗以及非心源性栓塞性卒中的抗血小板治疗。另外，还对其他许多特殊情况下的复发性卒中预防提供了推荐意见，包括动脉夹层分离、卯圆孔未闭、高同型半胱氨酸血症、高凝状态、镰状细胞病、脑静脉窦血栓形成、女性卒中（尤其是与妊娠和绝经后雌激素替代治疗相关性卒中）、脑出血后抗凝药的使用等，以及实施本指南及其在高危人群中应用的特定方法。

关键词：美国心脏协会科学声明脑缺血短暂性脑缺血发作卒中卒中预防

Pate.t forame. ovale.and cryptoge.ic stroke.diagnosis and update. in se.ondary stroke.pre.e.tion

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Stroke.& Vascular Ne.rology 2018年第2期3卷 84-91页

作者： Kristy Yuan scott e.ic kasner De.artme.t of Ne.rology University of PennsylvaniaPhiladelphiaPennsylvaniaUSA

The.pate.t forame. ovale.PFO),give. its high pre.ale.ce.in the.ge.e.al population and e.pe.ially in patie.ts with cryptoge.ic stroke.has long ge.e.ate. inve.tigation and de.ate.on its prope.sity for stroke.by paradoxical e.bolism and its manage.e.t for stroke.*** pe.dulum has swung for pe.cutane.us PFO closure.for se.ondary stroke.pre.e.tion in cryptoge.ic *** on a re.ie. of curre.t e.ide.ce.the.be.e.it from PFO closure.re.ie. on care.ul patie.t se.e.tion:those.unde. the.age.of 60 ye.rs with fe. to no vascular risk factors and e.bolic-appe.ring stroke.de.me. cryptoge.ic afte. thorough *** the.e.data look towards influe.cing guide.ine.state.e.ts and de.ice.approvals in the.future.patie.t se.e.tion re.ains the.crucial ingre.ie.t for clinical de.ision making and future.trials.

关键词： pre.e.tion diagnosis closure