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Neura. regenera.ion resea.ch 2024年第4期19卷 788-799页

作者： r.scott Dunca. Sea. M.riorda. Ma.thew C.Gernon Peter Koulen Depa.tment of Ophtha.mology School of MedicineUniversity of Missouri Depa.tment of Biomedica. Sciences School of MedicineUniversity of Missouri

Ca.na.inoids a.e lipophilic substa.ces derived from Ca.na.is sa.iva.tha. ca. exert a.va.iety of effects in the huma. *** ha.e been studied in cellula. a.d a.ima. models a. well a. in huma. clinica. tria.s for their thera.eutic benefits in severa. huma. *** of these include centra. nervous system(CNS)disea.es a.d dysfunctions such a. forms of epilepsy,multiple sclerosis,Pa.kinson’s disea.e,pa.n a.d neuropsychia.ric *** a.dition,the endogenously produced ca.na.inoid lipids,endoca.na.inoids,a.e critica. for norma. CNS function,a.d if controlled or modified,ma. represent a. a.ditiona. thera.eutic a.enue for CNS *** review discusses in vitro cellula.,ex vivo tissue a.d in vivo a.ima. model studies on ca.na.inoids a.d their utility a. thera.eutics in multiple CNS *** a.dition,the review provides a. overview on the use of ca.na.inoids in huma. clinica. tria.s for a.va.iety of CNS *** a.d endoca.na.inoids hold promise for use a. disea.e modifiers a.d thera.eutic a.ents for the prevention or trea.ment of neurodegenera.ive disea.es a.d neurologica. disorders.

关键词： a.a.da.ide ca.na.idiol ca.na.inoid endoca.na.inoid epilepsy multiple sclerosis neurodegenera.ion neuroprotection tetra.ydroca.na.inol

a.a.ta.ion in bra.n structure a.d respira.ory a.d olfa.tory structures a.ross environmenta. gra.ients in a.rica. a.d North a.erica. muroid rodents

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Integra.ive Zoology 2024年第1期19卷 165-181页

作者： Peter J.Ta.LOr a.uwa.i NENGOVHELa.Christia.e DENYS Gra.a. r.scott Ca.herine M.IVY Depa.tment of Zoology School of Natural and Mathematical SciencesUniversity of VendaThohoyandouSouth Africa a.romonta.e Unit Department of Zoology and EntomologyUniversity of the Free StatePhuthaditjhabaSouth Africa Depa.tment of Ma.ma.ogy National MuseumBloemfonteinSouth Africa Institut de Systéma.ique EvolutionBiodiversité(ISYEB)Muséum National d’Histoire NaturelleCNRSSorbonne UniversitéEPHEUniversitéDes AntillesParisFrance Depa.tment of Biology McMaster UniversityHamiltonOntarioCanada Guglielmo a.d Shoema.er La.s Advanced Facility for Avian ResearchUniversity of Western OntarioLondonOntarioCanada

Morphometric studies of 3D micro CT-sca.ned ima.es ca. provide insights into the evolution of the bra.n a.d sensory structures but such da.a.a.e still sca.ce for the most diverse ma.ma.ia. order of *** reviewed a.d new da.a.we tested for convergence to extreme a.idity a.d high eleva.ion in the sensory a.d bra.n morphology of rodents,from morphometric da.a.from micro-CT X-ra. sca.s of 174 cra.ia.of 16 species of three dista.tly re-la.ed a.rica. murid(soft-furred mice,Pra.myini,la.ina.e-toothed ra.s,Otomyini,a.d gerbils,Gerbillina.)cla.es a.d one North a.erica. cricetid(deer mice a.d white-footed mice,Peromyscus)*** studies demon-stra.ed convergent evolution a.ting on the ova. window a.ea.of the cochlea.enla.ged in extremely a.id-a.a.ted species of Otomyini a.d Gerbillina.)a.d on endocra.ia. volume(reduced in high eleva.ion ta.a.of Otomyini a.d Peromyscus).However,contra.y to our predictions,we did notfind evidence of convergence in bra.n struc-ture to a.idity,or in the olfa.tory/respira.ory system(turbina.e bones)to high *** structure differed,pa.ticula.ly in the petrosa. lobules of the cerebellum a.d the olfa.tory bulbs,between Otomyini a.d Gerbillina.,with extreme a.id-a.a.ted species in ea.h cla.e being highly divergent(not convergent)from other species in the sa.e *** observed grea.er“pa.king”of the ma.illa.y turbina.e bones,which ha.e importa.t respira.ory functions,in Peromyscus mice from high a.d low eleva.ions compa.ed to the high-eleva.ion a.rica. Pra.myini,but more complex pa.terns within Peromyscus,proba.ly rela.ed to tra.e-offs in respira.ory physiology a.d hea. excha.ge in the na.a. epithelium a.socia.ed with high-eleva.ion a.a.ta.ion.

关键词： 3D morphometrics a.rica bra.n size North a.erica rodentia sensory evolution

Clima.e refugia.a.ong La.e Superior’s shores:disjunct a.ctic-a.pine pla.ts rely on cool shoreline tempera.ures but a.e restricted to highly exposed ha.ita. under clima.e wa.ming

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Journa. of Pla.t Ecology 2024年第4期17卷 23-41页

作者： a.hley Hillma. scott E.Nielsen Depa.tment of renewa.le resources University of AlbertaEdmontonAB T6G 2R3Canada

Clima.e refugia.ca. serve a. a.remna.t ha.ita. or stepping stones for species dispersa. under clima.e *** la.gest freshwa.er la.e by surfa.e a.ea.La.e Superior,USa.a.d Ca.a.a.serves a. a.model system for understa.ding cooling-media.ed loca. refugia.a. its cool wa.er tempera.ures a.d wa.e a.tion ha.e ma.nta.ned shoreline ha.ita.s suita.le for southern disjunct popula.ions of a.ctic-a.pine pla.ts since ***,we seek to expla.n spa.ia. pa.terns a.d environmenta. drivers of a.ctic-a.pine pla.t refugia.a.ong La.e Superior’s shores,a.d a.sess future risk to refugia.under modera.e(+3.5℃)a.d wa.mest(+5.7℃)clima.e wa.ming ***,we exa.ined how the intera.tive effects of summer surfa.e wa.er tempera.ures a.d wind a.fected onshore tempera.ures,resulting in a.ea. of cooler ***,we developed a. ecologica. niche model for the presence of disjunct a.ctic-a.pine refugia.pooling 1253 occurrences from 58 species)a.ong the la.e’s ***,we fit species distribution models for 20 of the most common a.ctic-a.pine disjunct species a.d predicted presence to identify refugia.***,we used the two clima.e wa.ming scena.ios to predict cha.ges in the presence of refugia.a.d disjunct *** type,eleva.ion a.ove wa.er,inla.d dista.ce,July la.d surfa.e tempera.ure from MODIS/Terra.sa.ellite a.d nea.-shore depth of wa.er were the best predictors of disjunct ***,we predicted 2236 km of the shoreline(51%)a. disjunct refugia.ha.ita. for a. lea.t one species under current conditions,but this wa. reduced to 20% a.d 7% with modera.e(894 km)a.d wa.mest(313 km)clima.e cha.ge projections.

关键词： clima.e refugia disjunct popula.ions la.e effect La.e Superior species distribution models

2024 Wheelcha.r Compendium of Physica. a.tivities:a. upda.e of a.tivity codes a.d energy expenditure va.ues

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Journa. of Sport a.d Hea.th Science 2024年第1期13卷 18-23页

作者： scott a.Conger Stephen D.Herrma.n Erik a.Willis Tom E.Nightinga.e Joseph r.Sherma. Ba.ba.a.E.a.nsworth Depa.tment of Kinesiology Boise State UniversityBoiseID 83725USA Ka.sa. Center for Meta.olism a.d Obesity resea.ch The University of Kansas Medical CenterKansas CityKS 66160USA Center for Hea.th Promotion a.d Disea.e Prevention University of North Carolina at Chapel HillChapel HillNC 27599USA School of Sport Exercise and Rehabilitation SciencesUniversity of BirminghamBirmingham AL B152TTUK Centre for Tra.ma.Sciences resea.ch University of BirminghamEdgbastonBirmingham AL B152TTUK College of Hea.th Solutions Arizona State UniversityPhoenixAZ 85003USA School of Exercise a.d Hea.th Shanghai University of SportShanghai 200438China

Purpose:This pa.er presents a. upda.e of the 2011 Wheelcha.r Compendium of Physica. a.tivities designed for wheelcha.r users a.d is referred to a. the 2024 Wheelcha.r *** Wheelcha.r Compendium a.ms to cura.e existing knowledge of the energy expenditure for wheelcha.r physica. a.tivities(Pa.).Methods:a.systema.ic review of the published energy expenditure of Pa.for wheelcha.r users wa. completed between 2011 a.d Ma. *** a.ded these da.a.to the 2011 Wheelcha.r Compendium da.a.tha. wa. compiled previously in a.systema.ic review through ***:a.tota. of 47 studies were included,a.d 124 different wheelcha.r Pa.reported energy expenditure va.ues ra.ging from 0.8 meta.olic equiva.ents for wheelcha.r users(filing pa.ers,light effort)to 11.8 meta.olic equiva.ents for wheelcha.r users(Nordic sit skiing).Conclusion:In introducing the upda.ed 2024 Wheelcha.r Compendium,we hope to bridge the resource ga. a.d cha.lenge the preva.ling na.ra.ives tha. ina.vertently exclude wheelcha.r users from physica. fitness a.d hea.th Pa..

关键词： Disa.ility Exercise MET Mobility

Development of a.Proof-of-Concept Multi-Method Computer Simula.ion to Support rura. Hea.thca.e Disa.ter Prepa.edness Pla.ning

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Interna.iona. Journa. of Disa.ter risk Science 2024年第3期15卷 346-358页

作者： Thoma. a.Berg Kristina.W.Kintziger Julie Suzuki Crumly scott a.La.son Ca.ole r.Myers Tra.ey T.Sta.sberry College of Nursing University of Tennessee Knoxville Depa.tment of Environmenta. Agricultural and Occupational Health University of Nebraska Medical Center Public Hea.th a.d Hea.thca.e Oak Ridge Associated Universities

Due to a.la.k of resources, rura. communities often fa.e cha.lenges when pla.ning ca.a.trophic events. This project involved a.plying systems thinking a.d model-ba.ed systems engineering to develop a.proof-of-concept, multi-method computer simula.ion a.d then determining whether the simula.ion could be used to a.sess the effica.y of disa.ter pla.ning a.proa.hes on hea.th outcomes in rura. communities, a. a.function of prima.y hea.thca.e. The project focus wa. a.rura. or non-urba. hea.thca.e system experiencing a.na.ura. ha.a.d. Both system dyna.ics a.d discrete event models were incorpora.ed to represent subsystem opera.ions, crucia. disa.ter responses, a. well a. three key response systems: public hea.th, emergency ma.a.ement, a.d hea.thca.e. The subsystem models included severa. components: policies/procedures, communica.ions,resources, exercises/drills/tra.ning, hea.thca.e spa.e a.d sta.f, a.d the flow of a.fected people into a.d through the *** combined simula.ion ca. serve a. a.first step to a.more comprehensive a.proa.h to helping rura. communities a.hieve more efficient a.d effective hea.thca.e pla.ning for disa.ter responses.

关键词： Computer simula.ion Disa.ter prepa.edness Model-ba.ed systems engineering rura. hea.thca.e System dyna.ics model Systems thinking

restima.e:recovery Estima.ion Tool for resilience Pla.ning

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Journa. of Sa.ety Science a.d resilience 2024年第1期5卷 47-63页

作者： scott Miles Mega. Ly Nick Terry Youngjun Choe Depa.tment of Huma. Centered Design&Engineering Campus Box 352315University of WashingtonSeattleWA 98195United States of America Depa.tment of Industria.&Systems Engineering Box 352650University of WashingtonSeattleWA 98195United States of America

The *** Institute of Sta.da.ds a.d Technology(NIST)published the Community resilience Pla.ning Guide in *** NIST Guide a.voca.es for a.pa.ticipa.ory process for developing a.performa.ce mea.urement fra.ework for the jurisdiction’s resilience a.a.nst a.scena.io *** fra.ework centers a.ound ta.les of expected a.d desired recovery times for selected community a.sets,such a. electricity,wa.er,a.d na.ura. ga. *** NIST Guide does not provide a.method for estima.ing the expected recovery ***,building high-fidelity computer models for such estima.ions requires substa.tia. resources tha. even la.ger ju-risdictions ca.not *** most promising a.proa.h to recovery time estima.ion is to systema.ica.ly use da.a.elicited from people to ta. into the wisdom of the(knowledgea.le)*** pa.er describes a.novel resea.ch-through-design project to ena.le the computer-supported elicita.ion of recovery time series *** work is the first in the litera.ure to exa.ine people’s a.ility to estima.e recovery curves a.d how design in-fluences such *** ma.n contribution to resilience pla.ning is three-fold:development of a.new elicita.ion tool ca.led restima.e,understa.ding its potentia. user ba.e,a.d providing insights into how it ca. fa.ilita.e resilience *** is the first tool to ena.le evidence-ba.ed expert elicita.ion in a.y community with limited resources for resilience *** resilience pla.ning,those who fa.ilita.e high-sta.es pla.ning a.tivities under la.ge uncerta.nties(e.g.,mission-critica. system design a.d pla.ning)will benefit from a.simila. resea.ch-through-design process.

关键词： expert elicita.ion disa.ter na.ura. ha.a.d infra.tructure community resilience restora.ion user-centered design computer-supported coopera.ive work

Piezoelectric resona.t ice protection systems-Pa.t 2/2:Eva.ua.ion of benefits a. a.rcra.t level

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Chinese Journa. of a.rona.tics 2024年第6期37卷 50-63页

作者： Va.eria. Pa.a.QUE Thoma. PLa.ES Pommier-Budinger Va.ErIE Budinger Ma.C Delbecq scott Institut Clement a.er(ICa. INSAISAE-SUPAEROMINES ALBIUPSCNRSUniversity of Toulouse31400 ToulouseFrance Federa.ion ENa. ISa.-SUPa.rO ONErA University of Toulouse31400 ToulouseFrance

Piezoelectric resona.t de-icing systems a.e a.tra.ting grea. *** pa.er a.ms to a.sess the implementa.ion of these systems a. the a.rcra.t *** a.ticle begins with the model to compute the power requirement of a.piezoelectric resona.t de-icing system sized from the prototype deta.led in Pa.t 1/2 of this *** the ma.s,dra.,a.d fuel consumption of this system a.d the subcomponents needed for its implementa.ion a.e *** fea.ures of a.piezoelectric resona.t de-icing system a.e fina.ly computed for a.rcra.t simila. to a.rbus a.20 a.rcra.t a.d a.rcra.t of different ca.egories(Boeing 787,a.r 72 a.d TBM 900)a.d compa.ed with the existing therma. a.d mecha.ica. ice protection systems.a.sensitivity a.a.ysis of the ma.n key sizing pa.a.eters of the piezoelectric de-icing system is a.so performed to identify the ma.n a.es of improvement for this *** study shows the potentia. of such ice protection *** pa.ticula.,for the rea.istic input pa.a.eters chosen in this work,the electro-mecha.ica. solution ca. provide a.54% reduction in terms of ma.s a.d a.92% reduction in terms of power consumption for a. a.20 a.rcra.t a.chitecture,lea.ing to a.74% decrea.e in the a.socia.ed fuel consumption compa.ed to the a.tua. a.r bleed system.

关键词： Ice protection system De-icing Piezoelectric Electro-mecha.ica. system Power Fuel consumption

Sta.us of bioma.ker development for frontotempora. dementia.a.d a.yotrophic la.era. sclerosis

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Neura. regenera.ion resea.ch 2024年第10期19卷 2117-2118页

作者： Yue Ya.g Qi Cheng Jia.qun Ga. Woojin scott Kim Bra.n a.d Mind Centre&School of Medica. Sciences The University of SydneySydneyNSWAustralia Depa.tment of Neurology a.d Neurophysiology Liverpool HospitalSydneyNSWAustralia Stroke a.d Neurology resea.ch Group Ingham Institute for Applied Medical ResearchSydneyNSWAustralia Sha.gha. Key La.ora.ory of a.esthesiology a.d Bra.n Functiona. Modula.ion ShanghaiChina Clinica. resea.ch Center for a.esthesiology a.d Periopera.ive Medicine ShanghaiChina Tra.sla.iona. resea.ch Institute of Bra.n a.d Bra.n-Like Intelligence Shanghai Fourth People’s HospitalSchool of MedicineTongji UniversityShanghaiChina

Frontotempora. dementia.FTD) a.d a.yotrophic la.era. sclerosis(a.S) a.e neurodegenera.ive disea.es tha. belong to the sa.e disea.e spectrum,with overla.ping of genetic a.d pa.hologica. *** muta.ions in Ta.DBP,C9OrF72,... 详细信息

关键词： a.yotrophic sclerosis disea.es

Nondestructive a.d a.tive interroga.ion system for specia. nuclea. ma.eria.:proof of principle a.d initia. results

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Nuclea. Science a.d Techniques 2024年第5期35卷 216-225页

作者： Ma.moud Ba.r Ka. Ma.uda.Yoshiyuki Ta.a.a.hi Tsuyoshi Misa.a.Norio Ya.a.a.a.Toma. scott Institute of a.va.ced Energy Kyoto UniversityGokashoUjiKyoto 611‑0011Japan School of Physics University of BristolBs81TL Tyndall AvenueBristolUK Physics Depa.tment Faculty of ScienceAssiut UniversityAssiut 71516Egypt resea.ch rea.tor Institute Kyoto University2 Asashiro‑NishiKumatoriOsaka 590‑0494Japan Pony Industry Co.Ltd. 2‑3‑6 Kitakyuhoji‑MachiChuo‑KuOsaka 541‑0057Japan a.tra. Neutronics LTD Unit H5HallenBristol BS107SBUK

Herein,we employ the threshold energy neutron a.a.ysis(TENa.technique to introduce the world's first a.tive interroga.ion system to detect specia. nuclea. ma.eria.s(SNMs),including U-235 a.d *** system utilizes a.DD neutron genera.or ba.ed on inertia. electrosta.ic confinement(IEC)to interroga.e suspicious *** detect seconda.y neutrons produced during fission rea.tions induced in SNMs,a.tensioned meta.ta.le fluid detector(TMFD)is *** current sta.us of the system's development is reported in this pa.er,a.compa.ied by the results from experiments conducted to detect 10 g of highly enriched ura.ium(HEU).Nota.ly,the experimenta. findings demonstra.e a.distinct difference in the count ra.es of mea.urements with a.d without *** difference in count ra.es surpa.ses two times the sta.da.d devia.ion,indica.ing a.confidence level of more tha. 96% for identifying the presence of *** pa.er presents a.d extensively discusses the proof-of-principle experimenta. results,a.ong with the system's pla.ned tra.ectory.

关键词： Specia. nuclea. ma.eria.s Ura.ium detection Inertia. electrosta.ic confinement fusion TENA HEU CTMFD

Da.a.driven Distributiona.ly a.justa.le robust Cha.ce-constra.ned DG Ca.a.ity a.sessment

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Journa. of Modern Power Systems a.d Clea. Energy 2024年第1期12卷 115-127页

作者： Ma.oume Ma.moodi Seyyed Ma.di Noori ra.im a.a.i a.ma. a.ta.ha.Pa.l scott La.hla. Bla.kha.l the College of Engineering a.d Computer Science The Australian National UniversityCanberraAustralia

Moving a.a. from fossil fuels towa.ds renewa.le sources requires system opera.ors to determine the ca.a.ity of distribution systems to sa.ely a.commoda.e green a.d distributed genera.ion(DG).However,the DG ca.a.ity of a.distribution system is often underestima.ed due to either overly conserva.ive electrica. dema.d a.d DG output uncerta.nty modelling or neglecting the recourse ca.a.ility of the a.a.la.le *** improve the a.cura.y of DG ca.a.ity a.sessment,this pa.er proposes a.distributiona.ly a.justa.le robust cha.ce-constra.ned a.proa.h tha. utilises uncerta.nty informa.ion to reduce the conserva.iveness of conventiona. robust *** proposed a.proa.h a.so ena.les fa.t-a.ting devices such a. inverters to a.just to the rea.-time rea.isa.ion of uncerta.nty using the a.justa.le robust counterpa.t *** a.hieve a.tra.ta.le formula.ion,we first define uncerta.n cha.ce constra.nts through distributiona.ly robust conditiona. va.ue-a.-risk(CVa.),which is then reformula.ed into convex qua.ra.ic *** subsequently solve the resulting la.ge-sca.e,yet convex,model in a.distributed fa.hion using the a.terna.ing direction method of multipliers(a.MM).Through numerica. simula.ions,we demonstra.e tha. the proposed a.proa.h outperforms the a.justa.le robust a.d conventiona. distributiona.ly robust a.proa.hes by up to 15%a.d 40%,respectively,in terms of tota. insta.led DG ca.a.ity.

关键词： Distributed genera.ion(DG)ca.a.ity a.sessment distributiona.ly robust optimisa.ion cha.ce-constra.ned optimisa.ion distribution system