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A strategy for designing stable nanocrystalline alloys by thermo-kinetic synergy

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Journal of Materials science & Technology 2020年第8期36卷 21-31页

作者： H.R.Peng b.s Liu F.Liu state Key Laboratory of solidification Processing Northwestern Polytechnical UniversityXi’an710072China school of Materials and Chemical Engineering Xi’an Technological UniversityXi’an710021China Analytical and Testing Center Northwestern Polytechnical UniversityXi’an710072China

Aiming to design stable nanocrystalline(NC)materials,so far,it has been proposed to construct nanostructure stability maps in terms of thermodynamic parameters,while kinetic stabilization has seldom been considered,despite the synergy of thermodynamics and ***,the thermodynamically stabilized NC materials may be easily subjected to grain growth at high temperatures due to the weakly kinetic *** from the thermo-kinetic synergy,a stabilization criterion is proposed as a function of intrinsic solute parameters(*** activation energy for bulk diffusion and the segregation enthalpy),intrinsic solvent parameters(*** intrinsic activation energy for Gb migration and the Gb energy)and processing parameters(*** grain size,the temperature and the solute concentration).Using first-principles calculations for a series of combinations between fifty-one substitutional alloying atoms as solute atoms and Fe atom as fixed solvent atom,it is shown that the thermal stability neither simply increases with increasing the segregation enthalpy as expected by thermodynamic stabilization,nor monotonically increases with increasing the activation energy for bulk diffusion as described by kinetic *** combination of thermodynamic and kinetic contributions,the current stabilization criterion evaluates quantitatively the thermal stability,thus permitting convenient comparisons among NC materials involved by various combinations of the solute atoms,the solvent atoms,or the processing *** of this thermo-kinetic stabilization criterion has been tested by current experiment results of Fe-Y alloy and previously published data of Fe-Ni,Fe-Cr,Fe-Zr and Fe-Ag alloys,etc.,which opens a new window for designing NC materials with sufficiently high thermal stability and sufficiently small grain size.

关键词： Thermo-kinetic synergy Criterion Thermal stability Nanocrystalline materials

Plethysmograph training:A refinement for collection of respiration data in mice

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Animal Models and Experimental Medicine 2023年第4期6卷 369-374页

作者： Jorid b.sørli Karin s.Hougaard Niels Hadrup Chemical Work Environment The National Research Centre for the Working EnvironmentCopenhagenDenmark Department of Public Health University of CopenhagenCopenhagenDenmark Research Group for Risk-benefit National Food InstituteTechnical University of DenmarkLyngbyDenmark

Inhaled chemicals can harm the *** effects can result in distinct changes in respiratory patterns;the type of change indicates where and how the respiratory system is ***,changes in respiratory patterns may be detected at much lower substance concentrations than those that cause more serious effects,such as histopathological *** in respiratory patterns can be studied experimentally by monitoring the breathing of mice placed in plethysmographs and exposing head-out to the test *** method is well established;however,it is not known if training mice in being restrained in the plethysmograph could increase the quality of data *** we report the results of training mice to be restrained in plethysmographs for 5 consecutive days,with respect to body weight,respiratory parameters,and time spent in the plethysmograph,before they are removed because of unstable breathing *** mice tolerated the procedure better(measured by time in the plethysmograph)on the second day of training than the first *** did not change the breathing parameters between *** parameters stabilized within 5 min after the mice were placed in the plethysmographs on all *** was an average of 3%weight loss between the first and last days of the training,indicating that the training procedure placed some strain on the *** reduces the number of mice attempting to escape from the plethysmograph.

关键词： Alarie assay refinement sensory irritation

Regional stress field around the Taigu fault zone in shanxi Province,China

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Earthquake science 2015年第5期28卷 333-345页

作者： bin Li Zihong Li Mathilde b.s?rensen Reidar L?vlie Liqiang Liu Kuvvet Atakan Earthquake Administration of shanxi Province Department of Earth science University of Bergen state Key Laboratory of Earthquake Dynamics Institute of GeologyChina Earthquake Administration

A comprehensive study on regional stress field around the Taigu fault zone in shanxi Province, China, was performed in this study. To get a better understanding of the present-day stress status in this area, 31 focal mecha- nisms of ML 〉3 earthquakes since 1965 were compiled, and the b.st stress tensor was then inverted b.sed on the datab.se. Additionally, magnetic fabrics along the Taigu fault zone were investigated to get an indication of the regional stress field in the past. Our results show that the present-day stress field around the Taigu fault zone is characterized by astable NW-sE extension with a strike- slip component, consistent with the geological surveys and recent GPs data. Results from magnetic fabrics indicate that the orientations of principal stress axes from magnetic fabrics of sedimentary rocks in Neogene coincide to the orientations of principal stress axes from focal mecha- nisms. The south segment of the Taigu fault displays more complicated magnetic fabrics and more activity of mod- erate earthquakes. It is connected with the Mianshan west fault and intersects with NW-sE striking Fenyang fault and the north fault of the Lingshi uplift at the south edge of Taiyuan b.sin. This may be the area needing more atten- tion in terms of seismic risk along the Taigu fault.

关键词： Focal mechanisms stress tensor inversion Magnetic fabric Taigu fault shanxi rift

Neuroinflammation revisited through the microglial lens

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Neural Regeneration Research 2025年第7期20卷 1989-1990页

作者： Renato socodato João b.Relvas Institute of Research and Innovation in Health(i3s)and Institute for Molecular and Cell biology(IbMC) University of PortoPortoPortugal Department of biomedicine Faculty of Medicine of the University of Porto(FMUP)PortoPortugal

Neuroimmunology is emerging as a pivotal field,shedding light on the intricate dialogues between the central nervous system(CNs)and the immune *** exploration is particularly significant in understanding microglia,the CNs’s innate immune cells,beyond the conventional conflation of“neuroinflammation”and“microglial activation.”This conflation has clouded the true complexity of these processes,potentially stalling scientific progress and the development of new *** challenge the long-standing perspectives that have oversimplified these interactions,advocating for a deeper exploration of the dynamic relationship between neuroinflammation and microglial *** dissecting specific molecular pathways,we aim to illuminate their elaborate roles in neuroinflammatory responses,especially in the context of Alzheimer’s disease(AD).Here,neuroinflammation is not merely a passive observer or a direct antagonist but a complex agent in the disease’s *** article calls for a significant paradigm shift towards an integrative,multi-omics approach to *** such a comprehensive framework is crucial for advancing our understanding of neuroinflammatory conditions and paving the way for targeted therapeutic strategies for brain diseases.

关键词： inflammation simplified activation

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大麦基因目录

国外农学（麦类作物） 1993年第3期 4-8页

作者： b.s gaard 黄志仁

本汇编中,大麦基因目录第一栏是基因座,它相当于一个互补的基因组;第二栏是同物异名符号;第三栏是该基因所控制的性状;第四栏是等位基因数,这些等位基因是在一个或几个密切相关的遗传背景上诱发的控制不同突变体表现的基因.对于14个同... 详细信息

本汇编中,大麦基因目录第一栏是基因座,它相当于一个互补的基因组;第二栏是同物异名符号;第三栏是该基因所控制的性状;第四栏是等位基因数,这些等位基因是在一个或几个密切相关的遗传背景上诱发的控制不同突变体表现的基因.对于14个同工酶基因座因未能区分出等位基因数,故用星号(*)标出.(未定位于染色体上的基因以及某些基因的遗传原种保存单位和文献号均因篇幅有限而从略,读者若需要时可查阅原文——译者)。

关键词：大麦基因目录

一种光纤光栅传感实验仪的可靠性分析(英文)

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仪器仪表学报 2008年第4期29卷 673-678页

作者：朱萍玉 Dhillon b.s. 李学军宾光富湖南科技大学机械设备健康维护湖南省重点实验室渥太华大学机械工程系

光纤光栅作为一种传感单元可以测试应变、温度和压力等物理量。近年来,可用于光纤光栅信号解调的技术和仪器相继出现,并在不同的场合得到了很好的应用。但由于制造、安装和操作等原因,这些仪器的可靠性问题也开始引起不同程度的关注。... 详细信息

光纤光栅作为一种传感单元可以测试应变、温度和压力等物理量。近年来,可用于光纤光栅信号解调的技术和仪器相继出现,并在不同的场合得到了很好的应用。但由于制造、安装和操作等原因,这些仪器的可靠性问题也开始引起不同程度的关注。仪器的可靠性分析是其设计过程中不可缺少的重要环节之一。以一种基于匹配解调技术的准分布式光纤光栅解调仪为例,介绍了该仪器的基本组成和原理;采用故障树法从机械和光电器件的可能出现的如光纤光栅脆断、螺钉松动和脱焊等故障和失效形式出发,根据光路配置、电路以及机械结构分析了可能的故障模式,计算了可靠性。结论有利于对这类仪器的故障诊断和维护。

关键词：可靠性分析光纤传感器故障树光纤光栅

Decision support for the development,simulation and optimization of dynamic process models

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Frontiers of Chemical science and Engineering 2022年第2期16卷 210-220页

作者： Norbert Asprion Roger böttcher Jan schwientek Johannes Höller Patrick schwartz Charlie Vanaret Michael bortz b.sF sE 67063 LudwigshafenGermany Fraunhofer ITWM 67663 KaiserslauternGermany

simulation is b.sides experimentation the major method for designing,analyzing and optimizing chemical *** ability of simulations to reflect real process behavior strongly depends on model *** and adaption of process models are usually b.sed on available plant *** such a model in various simulation and optimization studies can support the process designer in his *** steady state models there is also a growing demand for dynamic models either to adapt faster to changing conditions or to reflect batch *** this contribution challenges of extending an existing decision support framework for steady state models to dynamic models will be discussed and the resulting opportunities will be demonstrated for distillation and reactor examples.

关键词： decision support multicriteria optimization model validation dynamic model sensitivity analysis

brain-derived neurotrophic factor signaling in the neuromuscular junction during developmental axonal competition and synapse elimination

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Neural Regeneration Research 2025年第2期20卷 394-401页

作者： Josep Tomàs Víctor Cilleros-Mañé Laia Just-borràs Marta balanyà-segura Aleksandra Polishchuk Laura Nadal Marta Tomàs Carolina silvera-simón Manel M.santafé Maria A.Lanuza Unitat d’Histologia i Neurobiologia(UHNeurob) Facultat de Medicina i Ciències de la SalutUniversitat Rovira i VirgiliReusSpain

During the development of the nervous system,there is an overproduction of neurons and *** competition between neighboring nerve endings and synapses performing different activity levels leads to their elimination or *** have extensively studied the involvement of the brain-derived neurotrophic factor-Tropomyosin-related kinase b receptor neurotrophic retrograde pathway,at the neuromuscular junction,in the axonal development and synapse elimination process versus the synapse *** purpose of this review is to describe the neurotrophic influence on developmental synapse elimination,in relation to other molecular pathways that we and others have found to regulate this *** particular,we summarize our published results b.sed on transmitter release analysis and axonal counts to show the different involvement of the presynaptic acetylcholine muscarinic autoreceptors,coupled to downstream serine-threonine protein kinases A and C(PKA and PKC)and voltage-gated calcium channels,at different nerve endings in developmental *** dynamic changes that occur simultaneously in several nerve terminals and synapses converge across a postsynaptic site,influence each other,and require careful studies to individualize the mechanisms of specific *** describe an activity-dependent balance(related to the extent of transmitter release)between the presynaptic muscarinic subtypes and the neurotrophin-mediated Trkb/p75NTR pathways that can influence the timing and fate of the competitive interactions between the different axon *** downstream displacement of the PKA/PKC activity ratio to lower values,both in competing nerve terminals and at postsynaptic sites,plays a relevant role in controlling the elimination of supernumerary ***,calcium entry through L-and P/Q-subtypes of voltage-gated calcium channels(both channels are present,together with the N-type channel in developing nerve terminals)contributes to red

关键词： acetylcholine release adenosine receptors axonal competition brain-derived neurotrophic factor calcium channels motor end-plate muscarinic acetylcholine receptors postnatal synapse elimination serine kinases tropomyosin-related kinase receptorb

Nonsmooth semi-Infinite Minmax Programming Involving Generalized(Φ, ρ)-Invexity

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Journal of systems science & Complexity 2015年第4期28卷 857-875页

作者： UPADHYAY b b MIsHRA s K Department of b.sic sciences & Humanities National Institute of Technology

This paper introduces some new generalizations of the concept of （~, p）-invexity for non- differentiable locally Lipschitz functions using the tools of Clarke subdifferential. These functions are used to derive the necessary and sufficient optimality conditions for a class of nonsmooth semi-infinite minmax programming problems, where set of restrictions are indexed in a compact set. Utilizing the sufficient optimality conditions, the authors formulate three types of dual models and establish weak and strong duality results. The results of the paper extend and unify naturally some earlier results from the literature.

关键词： Duality, generalized invexity locally Lipschitz functions, minmax programming, semi-infinite programming.