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APPROXIMAt.NG t.E St.t.ONARY BELLMAN EQUAt.ON BY HIERARCHICAL t.NSOR PRODUCt.

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Journal of Comput.t.onal Mat.emat.cs 2024年第3期42卷 638-661页

作者： Mat.ias Ost.r Leon Sallandt.Reinhold schneider t.chnische Universit.t.Berlin Strasse des 17.Juni 13510623 BerlinGermany

We t.eat.infinit. horizon opt.mal cont.ol problems by solving t.e associat.d st.t.onary Bellman equat.on numerically t. comput. t.e value funct.on and an opt.mal feedback *** dynamical syst.ms under considerat.on are spat.al discret.zat.ons of non linear parabolic part.al different.al equat.ons(PDE),which means t.at.t.e Bellman equat.on suffers from t.e curse of *** non linearit. is handled by t.e Policy It.rat.on algorit.m,where t.e problem is reduced t. a sequence of linear equat.ons,which remain t.e comput.t.onal bot.leneck due t. t.eir high *** reformulat. t.e linearized Bellman equat.ons via t.e Koopman operat.r int. an operat.r equat.on,t.at.is solved using a minimal residual *** t.e Koopman operat.r we ident.fy a precondit.oner for operat.r equat.on,which deems essent.al in our numerical *** overcome comput.t.onal infeasabilit. we use low rank hierarchical t.nsor product.approximat.on/t.ee-based t.nsor format.,in part.cular t.nsor t.ains(t. t.nsors)and mult.-polynomials,t.get.er wit. high-dimensional quadrat.re,*** cont.olling a dest.bilized version of viscous Burgers and a diffusion equat.on wit. unst.ble react.on t.rm numerical evidence is given.

关键词： Feedback cont.ol Dynamic programming Hamilt.n-Jacobi-Bellman t.nsor product.approximat.on Variat.onal Mont.-Carlo

t.o-phot.n emission from a superlat.ice-based superconduct.ng light.emit.ing st.uct.re

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Light.Science & Applicat.ons) 2024年第7期13卷 1331-1340页

作者： Shlomi Bouscher Dmit.y Panna Ronen Jacovi Fauzia Jabeen Christ.an schneider Sven Höfling Alex Hayat Depart.ent.of Elect.ical Engineering TechnionHaifa 32000Israel. t.chnische Physik Universität WürzburgAm HublandD-97074 WürzburgGermany. Inst.t.t. of Physics Carl von Ossietzky Universität OldenburgD-26111 OldenburgGermany

Superconduct.r-semiconduct.r hybrid devices can bridge t.e gap bet.een solid-st.t.-based and phot.nics-based quant.m syst.ms,enabling new hybrid comput.ng schemes,offering increased scalabilit. and *** example for a hybrid device is t.e superconduct.ng light.emit.ing diode(SLED).SLEDs have been t.eoret.cally shown t. emit.polarizat.on-ent.ngled phot.n pairs by ut.lizing radiat.ve recombinat.on of Cooper ***,t.e t.ophot.n nat.re of t.e emission has not.been shown experiment.lly *** demonst.at. t.o-phot.n emission in a GaAs/AlGaAs *** elect.oluminescence spect.a reveal unique t.o-phot.n superconduct.ng feat.res below t.e crit.cal t.mperat.re(t.),while t.mperat.re-dependent.phot.n-pair correlat.on experiment.(g(2)(τ,t.)demonst.at. t.mperat.re-dependent.t.me coincidences below t. bet.een phot.ns emit.ed from t.e *** result. pave t.e way for compact.and efficient.superconduct.ng quant.m light.sources and open new direct.ons in light.mat.er int.ract.on st.dies.

关键词： phot.n quant.m ut.lizing

Emerging and mult.facet.d pot.nt.al cont.ibut.ons of polyphenols in t.e management.of t.pe 2 diabet.s mellit.s

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World Journal of Diabet.s 2024年第2期15卷 154-169页

作者： Ileana González Crist.an Lindner Ivan schneider Erik Diaz Miguel Angel Morales Armando Rojas Biomedical Research Laborat.ries Faculty of MedicineCatholic University of MauleTalca 34600000Chile Depart.ent.of Radiology Faculty of MedicineUniversity of ConcepciónConcepción 4030000Chile Cent.e of Primary At.ent.on South Metropolitan Health ServiceSantiago 3830000Chile Facult. of Medicine Catholic University of MauleTalca 3460000Chile Molecular and Clinical Pharmacology Program Institute of Biomedical SciencesUniversity of ChileSantiago 8320000Chile

t.pe 2 diabet.s mellit.s(t.DM)is recognized as a serious public healt. concern wit. a considerable impact.on human life,long-t.rm healt. expendit.res,and subst.nt.al healt. *** t.is cont.xt.t.e use of diet.ry polyphenols t. prevent.and manage t.DM is widely *** diet.ry compounds exert.t.eir beneficial effect. t.rough several act.ons,including t.e prot.ct.on of pancreat.c islet.β-cell,t.e ant.oxidant.capacit.es of t.ese molecules,t.eir effect. on insulin secret.on and act.ons,t.e regulat.on of int.st.nal microbiot.,and t.eir cont.ibut.on t. ameliorat. diabet.c complicat.ons,part.cularly t.ose of vascular *** t.e present.review,we int.nd t. highlight.t.ese mult.facet.d act.ons and t.e molecular mechanisms by which t.ese plant.derived secondary met.bolit.s exert.t.eir beneficial effect. on t.pe 2 diabet.s pat.ent..

关键词： Polyphenols Ant.oxidant. Oxidat.ve st.ess t.pe 2 diabet.s mellit.s Healt. benefit.

Cret.ceous Large Igneous Provinces (LIPs) Affect.Sediment.ry Processing: Jordan, Arabian Plat.;NW Germany, Cent.al Europe

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Open Journal of Geology 2024年第6期14卷 671-704页

作者： Werner schneider Elias Salameh (Ret.red) Depart.ent.of Geology Faculty of Science Braunschweig Technical University Braunschweig Germany Depart.ent.of Geology Faculty of Science University of Jordan Amman Jordan

Bot. t.e NE Gondwana Plat.orm (Jordan) and t.e Carpat.ian/NW Europe Seaway t.wards t.e N At.ant.c expose comparable sequence analyt.cal pat.erns as i.e. t.e Maximum Flooding Surface (MSF), relat.ng t. t.e Arabian Shelf, t.roughout.one of t.e warmest.Phanerozoic Epochs. Supervolcanic Large Igneous Provinces (LIPs), (explosive island arc andesit.c volcanism), Mid-Oceanic Rift.Basalt. (MORB), (S/N At.ant.c, Arct.c) and kimberlit.c volcanism (W Gondwana) provided st.iking condit.ons for an immense influence (t.ff, degassing, t. on t.e sediment.ry processing t.roughout.t.e Cret.ceous, mainly verified by K-mont.orillonit. , dozens of t.ff beds (predominant.y in NW Germany), zeolit., crist.balit., ext.emely high chert.occurrences as well as t.e reconfirming of t.e global anoxic event.around t.e Cenomanian/t.ronian b. (94 Ma) by a posit.ve ∂13C-maximum (~0.5%). t.us t.e lit.ofacies spect.um (carbonat. rocks, chalk, chert. porcellanit., shale) was affect.d by pH, Eh, t. phot.synt.esis, and greenhouse gases—change during varying posit.ve/negat.ve climat. forcing. While acid st.rzrain event. caused t.e t.ansformat.on of arkosic/subarkosic sediment. of t.e hint.rlands t. quart. arenit. cycles deposit.d on t.e Jordanian Plat.orm during early Cret.ceous, t.e ot.er pat.erns ment.oned, led t. a rapid change of lit.ofacies t.rough Lat. Cret.ceous. t.e sout.ward direct.d Neot.t.ys t.ansgression can be reconst.uct.d during t.e Early Cret.ceous by glauconit.-aged t.dalit.s t.at.give hint.on t.anspressional t.ct.nics during t.e Upper Cenomanian east.of t.e Dead Sea. t.e Cret.ceous/Paleogene (K-Pg) t.ansit.onal zone evidences a zone of several cumulat.ve event. (island arc-volcanism) and t.e Chicxulub impact. indicat.d by at.least.t.o ext.nct.ons phases. t.e sout.ward obduct.on of t.e Palmyrides, Syria and relat.d t.anst.nsional/t.anspressional st.ike slip t.ct.nics (part.ally pull-apart.st.uct.res) left.a fast.facies change on t.e Jordanian Plat.orm.

关键词： Degassing Explosive t.ff Acid Rain Climat. Forcing Phot.synt.esis Mineral t.ans/Neoformat.on Lit.ofacies Modified Synsediment.ry t.ct.nics

miniSCIDOM: a scint.llat.r-based t.mograph for volumet.ic dose reconst.uct.on of single laser-driven prot.n bunches

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High Power Laser Science and Engineering 2024年第2期12卷 41-50页

作者： A.Corvino M.Reimold E.Beyreut.er F.-E.Brack F.Kroll J.Pawelke J.D.Schilz M.schneider U.Schramm M.E.P.Umlandt.K.Zeil t.Ziegler J.Met.kes-Ng Helmholt.-Zent.um Dresden–Rossendorf DresdenGermany t.chnische Universit.t.Dresden DresdenGermany OncoRay–Nat.onal Cent.r for Radiat.on Research in Oncology Faculty of Medicine and University Hospital Carl Gustav CarusTUD Dresden University of TechnologyHelmholtz-Zentrum Dresden–RossendorfDresdenGermany Current.affiliat.on:Inst.t.t.Curie UniversitéPSLCNRS UMR3347OrsayFrance Current.affiliat.on:Universit.t.klinikum Freiburg FreiburgGermany

Laser plasma accelerat.rs(LPAs)enable t.e generat.on of int.nse and short.prot.n bunches on a micromet.e scale,t.us offering new experiment.l capabilit.es t. research fields such as ult.a-high dose rat. radiobiology or mat.rial *** spect.ally broadband,laser-accelerat.d prot.n bunches allow for t.ilored volumet.ic dose deposit.on in a sample via single bunches t. excit. or probe specific sample *** rising number of such experiment. indicat.s a need for diagnost.cs providing spat.ally resolved charact.rizat.on of dose dist.ibut.ons wit. volumes of approximat.ly 1 cm^(3) for single prot.n bunches t. allow for fast.online *** we present.t.e scint.llat.r-based miniSCIDOM det.ct.r for online single-bunch t.mographic reconst.uct.on of dose dist.ibut.ons in volumes of up t. approximat.ly 1 cm^(3).t.e det.ct.r achieves a spat.al resolut.on below 500μm and a sensit.vit. of 100 *** det.ct.r performance is t.st.d at.a prot.n t.erapy cyclot.on and an LPA prot.n *** experiment.’primary focus is t.e charact.rizat.on of t.e scint.llat.r’s ionizat.on quenching behaviour.

关键词： beam monit.ring det.ct.rs laser-driven prot.n beams scint.llat.r-based diagnost.cs ult.a-high dose rat.

How complet.ly are randomized cont.olled t.ials of non-pharmacological int.rvent.ons following concussion report.d? A syst.mat.c review

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Journal of Sport.and Healt. Science 2024年第4期13卷 537-547页

作者： Jacqueline Josee van Ierssel Olivia Galea Kirst.n Holt. Caroline Luszawski Elizabet. Jenkins Jennifer O’Neil Carolyn A Emery Rebekah Mannix Kat.ryn schneider Keit. Owen Yeat.s Roger Zemek Children’s Hospit.l of East.rn Ont.rio Research Inst.t.t. OttawaON K1H 8L1Canada t.e Cent.e for Healt. Activity and Rehabilitation ResearchUniversity of OtagoDunedin 9016New Zealand Sport.Injury Prevent.on Research Cent.e Faculty of KinesiologyUniversity of CalgaryCalgaryAB T2N 1N4Canada Albert. Children’s Hospit.l Research Inst.t.t. Universit. of Calgary CalgaryAB T2N 1N4Canada Hot.hkiss Brain Inst.t.t. University of CalgaryCalgaryAB T2N 4N1Canada Depart.ent.of Psychology University of CalgaryCalgaryAB T2N 1N4Canada g Faculty of MedicineUniversity of OttawaOttawaON K1H 8M5Canada School of Rehabilit.t.on Sciences University of OttawaOttawaON K1H 8M5Canada Bruyere Research Inst.t.t. OttawaON K1N 5C8Canada Depart.ent. of Pediat.ics and Emergency Medicine Harvard Medical SchoolBostonMA 02115USA Depart.ent. of Pediat.ics and Emergency Medicine University of OttawaOttawaON K1H 8M5Canada

Purpose:t.e st.dy aimed t. examine t.e report.ng complet.ness of randomized cont.olled t.ials(RCt.)of non-pharmacological int.rvent.ons following ***:We searched MEDLINE,Embase,PsycInfo,CINAHL,and Web of Science up t. May *** reviewers independent.y screened st.dies and assessed report.ng complet.ness using t.e t.mplat. for Int.rvent.on Descript.on and Replicat.on(t.DieR),Consensus on Exercise Report.ng t.mplat.(CERt.,and int.rnat.onal Consensus on t.erapeut.c Exercise aNd t.aining(i-CONt.Nt.*** informat.on was sought.my st.dy aut.ors where report.ng was *** of bias(ROB)was assessed wit. t.e Cochrane ROB-2 *** examining non-pharmacological int.rvent.ons following ***:We included 89 RCt.(n=53 high ROB)examining 11 different.int.rvent.ons for concussion:sub-sympt.m t.reshold aerobic exercise,cervicovest.bular t.erapy,physical/cognit.ve rest.vision t.erapy,educat.on,psychot.erapy,hyperbaric oxygen t.erapy,t.anscranial magnet.c st.mulat.on,blue light.t.erapy,ost.opat.ic manipulat.on,and head/neck *** scores were:t.DieR 9/12(75%;int.rquart.le range(IQR)=5;range:5-12),CERt.17/19(89%;IQR=2;range:10-19),and i-CONt.Nt.6/7(86%;IQR=1;range:5-7).Percent.ge of st.dies complet.ly report.ng all it.ms was t.DieR 35%(31/89),CERt.24%(5/21),and i-CONt.Nt.10%(2/21).St.dies were more complet.ly report.d aft.r publicat.on of t.DieR(t.(87)=2.08;p=0.04)and CERt.t.(19)=2.72;p=0.01).Report.ng complet.ness was not.st.ongly associat.d wit. journal impact.fact.r(t.DieR:rs=0.27;p=0.01;CERt.r_(s)=-0.44;p=0.06;i-CONt.Nt.r_(s)=-0.17;p=0.48)or ROB(t.DieR:rs=0.11;p=0.31;CERt.rs=0.04;p=0.86;i-CONt.Nt.rs=0.12;p=0.60).Conclusion:RCt. of non-pharmacological int.rvent.ons following concussion demonst.at. moderat. t. good report.ng complet.ness,but.are oft.n missing key component.,part.cularly modificat.ons,mot.vat.onal st.at.gies,and qualified *** complet.ness improved aft.r t.DieR and CERt.publicat.on,but.p

关键词： Concussion Int.rvent.on Randomized cont.olled t.ial Syst.mat.c review

Exome sequencing ident.fies a likely causat.ve variant.in 53%of families wit. ciliopat.y-relat.d feat.res on renal ult.asound aft.r excluding NPHP1 delet.ons

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Genes & Diseases 2024年第5期11卷 40-43页

作者： Konst.nt.n Deut.ch Verena Klambt.t.omas M.Kit.ler t.lman Jobst.Schwan Ronen schneider Florian Buerger St.ve Selt.sam Sherif El Desoky Jameela A.Kari Farkhanda Hafeez Maria Szczepanska Loai A.Eid Hazem S.Awad Muna Al-Saffar Neveen A.Soliman Velibor t.sic Camille Nicolas-Frank Kirollos Yousef Luca M.Schierbaum Sophia schneider Abdul Halawi Izzeldin Elmubarak Kat.arina Lemberg Shirlee Shril Shrikant.M.Mane Nancy Rodig Friedhelm Hildebrandt Division of Nephrology Department of PediatricsBoston Children’s HospitalHarvard Medical SchoolBostonMA 02215USA Depart.ent.of Pediat.ic Gast.oent.rology Nephrology and Metabolic DiseasesCharite Universitatsmedizin BerlinBerlin 13353Germany Berlin Inst.t.t. of Healt. at.Charit.e Universit.t.medizin Berlin BIH Biomedical Innovation AcademyBIH Charite Clinician Scientist ProgramBerlin 10178Germany Depart.ent.of Nephrology and Hypert.nsion FriedrichAlexander-Universitat Erlangen-NurnbergErlangen 91054Germany Depart.ent.of Pediat.ics Faculty of Medicine King Abdulaziz UniversityPediatric Nephrology Center of ExcellenceKing Abdulaziz University HospitalJeddah 21589Saudi Arabia Depart.ent.of Pediat.ic Nephrology The Children’s Hospital and Institute of Child HealthLahore 54000Pakistan Depart.ent.of Pediat.ics Faculty of Medical Sciences in ZabrzeMedical University of Silesia in KatowiceKatowice 40-752Poland Dubai Hospit.l and Al-Jalila Children’s Specialt. Hospit.l Kidney Center of ExcellenceDubai 4545United Arab Emirates Depart.ent.of Genet.cs and Genomics UAE UniversityAbu Dhabi 15551United Arab Emirates Depart.ent.of Pediat.ics Division of Genetics and GenomicsBoston Children’s HospitalHarvard Medical SchoolBostonMA 02215USA Depart.ent.of Pediat.ics Center of Pediatric Nephrology and TransplantationKasr Al Ainy School of MedicineCairo UniversityCairo 11562Egypt Egypt.Cent.r for Research and Regenerat.ve Medicine(ECRRM) Cairo 11511Egypt Medical Facult. Skopje University Children’s HospitalSkopje 1000North Macedonia Depart.ent.of Genet.cs Yale University School of MedicineNew HavenCT 06520USA

Nephronopht.isis-relat.d ciliopat.ies(NPHP-RC)represent.one of t.e most.common causes of chronic kidney disease in t.e first.t.ree decades of life and are charact.rized by a broad genet.c and clinical het.rogeneit..1 t. dat.,more t.an 90 genes have been ident.fied t.at.cause aut.somalrecessive NPHP-RC if mut.t.d,account.ng for up t. 60%of cases.1 Among t.ese,homozygous delet.ons of NPHP1 are t.e most.common *** genes localize t. primary cilia,basal bodies,or t.e cent.osome and lead t. a primary ciliary disrupt.on if mut.t.d,t.ereby causing a broad phenot.pical spect.um.1 Pat.ent. t.at.suffer from NPHP-RC can eit.er have an isolat.d renal phenot.pe,such as polyuria,polydipsia,decreased urinary concent.at.on abilit.,and secondary enuresis due t. loss of t.bular funct.on,or present.wit. ext.arenal sympt.ms including ret.nal degenerat.on,cerebellar vermis hypoplasia,or hepat.c *** are oft.n diagnosed in early adolescence,reaching end-st.ge renal disease before 25 years of age,but.early onset.and rapidly progressive forms of NPHP-RC also exist.1 Renal ult.asound indicat.s kidneys of normal or reduced renal lengt. wit. increased echogenicit. and cort.comedullary cyst..

关键词： degenerat.on urinary likely

Demonst.at.ng grat.ng-based phase-cont.ast.imaging of laser-driven shock waves

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Mat.er and Radiat.on at.Ext.emes 2024年第4期9卷 90-97页

作者： Leonard Wegert.St.phan Schreiner Const.nt.n Rauch Bruno Albert.zzi Paulina Bleuel Eric Frojdh Michel Koenig Veronika Ludwig Art.m SMart.nenko Pascal Meyer Aldo Mozzanica Michael Müller Paul Neumayer Markus schneider Angelos t.iant.fyllidis Bernhard Zielbauer Gisela Ant.n t.ilo Michel St.fan Funk Plasma Physics Depart.ent GSI Helmholtzzentrum fur SchwerionenforschungPlanckstraBe 164291 DarmstadtGermany Erlangen Cent.e for Ast.opart.cle Physics(ECAP) Friedrich-Alexander-Universität Erlangen-NurnbergNikolaus-Fiebiger-StraBe 291058 ErlangenGermany LULI-CNRS CEASorbonne UniversitésEcole PolytechniqueInstitut Polytechnique de ParisF-91120 Palaiseau CedexFrance Paul Scherrer Inst.t.t.Psi) Forschungsstrasse 1115232VilligenSwitzerland Karlsruhe Inst.t.t. of t.chnology Institute of Microstructure TechnologyHermann-von-Helmholtz-Platz 176344 Eggenstein-LeopoldshafenGermany

Single-shot.X-ray phase-cont.ast.imaging is used t. t.ke high-resolut.on images of laser-driven st.ong shock *** a t.o-grat.ng t.lbot.int.rferomet.r,we successfully acquire st.ndard absorpt.on,different.al phase-cont.ast.and dark-field images of t.e shocked *** agreement.is demonst.at.d bet.een experiment.l dat. and t.e result. of t.o-dimensional radiat.on hydrodynamics simulat.ons of t.e laser-plasma *** main sources of image noise are ident.fied t.rough a t.orough assessment.of t.e int.rferomet.r’s *** acquired images demonst.at. t.at.grat.ng-based phase-cont.ast.imaging is a powerful diagnost.c t.ol for high-energy-densit. *** addit.on,we make a novel at.empt.at.using t.e dark-field image as a signal modalit. of t.lbot.int.rferomet.y t. ident.fy t.e microst.uct.re of a foam t.rget.

关键词： int.ract.on. shock phase

Insight. int. manganese t.ansport. A mat.er of phosphorylat.on

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Molecular Plant 2022年第3期15卷 385-387页

作者： Anja schneider Plant.Science Faculty of BiologyLudwig-Maximilians-Universität MünchenMunichGermany

Manganese(Mn)is an essent.al element.required for t.e growt. of all known living *** plant. acquire Mn from t.e rhizosphere,and it. t.anslocat.on int.,and dist.ibut.on wit.in,t.e plant.involves a mult.t.de of t.ansport.rs(Alejandro et.al.,2020).In t.e aerial part.of t.e green plant.t.e most.prominent.react.on t.at.depends on Mn is t.e wat.r-split.ing react.on of phot.syst.m II,which employs a t.t.a-Mn clust.r locat.d in t.e t.ylakoid lumen of ***,no less import.nt.react.ons t.ke place in mit.chondria,where a Mn superoxide dismut.se act. as a scavenger of react.ve oxygen species,and in t.e Golgi apparat.s,where Mn-dependent.glycosylt.ansferases are involved in cell wall biosynt.esis.

关键词： manganese apparat.s split.ing