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Seasonal influence and local factors affecting macroinvertebrate structure in a high-altitude Andean stream

Journal of Mountain Science 2020年第6期17卷 1374-1386页

作者： scheibler erica e FeRNáNDeZ CAMPóN Florencia LAGOS SILNIK Susana WeLLNITZ Todd Laboratorio de entomologia IADIZACCT CONICET MendozaAvenida Ruiz Leal s/nParque Gral.San MartinCC 5075500MendozaArgentina Consejo Nacional de Investigaciones Cientificas y Tecnicas(CONICeT) Avenida Rivadavia 1917C1033AAJCABAArgentina Facultad de Ciencias exactas y Naturales Universidad Nacional de CuyoPadre Jorge Contreras 1300M5502JMA MendozaArgentina Biology Department University o f Wisconsin-Eau Claire105 Garfield Avenue54701Eau ClaireWisconsinUSA

Small water bodies are critical for maintaining freshwater biodiversity,but are among the least investigated aquatic *** examined physical and chemical variables at two reaches in Arroyo Tambillos,a small,high-elevation Andean stream,in NW Mendoza province,Argentina,across four seasons to examine how local factors and seasonality affected the structure of the macroinvertebrate *** Arroyo Tambillos community was numerically dominated by ephemeropterans(mainly Massartellopsis irarrazavali)while the dipteran Chironomidae were the most species *** macroinvertebrate abundance was highest in summer,driven mainly by taxa that were secondary in dominance(Austrelmis *** Andesiops peruvianus),while richness did not differ between ***,benthic composition was different in Fall 2013(March)compared to other seasons,largely because of the increased abundance of *** correspondence analysis discriminated Chironomidae species distributions in Fall 2013 by substrate type(i.e.,big and small boulder substrate).By contrast,discharge,velocity,and depth were the variables which most affected the macroinvertebrate abundance and *** to our expectations,most community changes observed occurred in fall instead of ***-kryal stream communities like the one described here have become increasingly important for conserving mountain stream biodiversity as anthropogentic impacts and climate change increasingly impact lower stream ***,monitoring high-altitude streams like the Arroyo Tambillos may be critical for preventing the future loss of unique and sensitive stream biota.

关键词： ephemeroptera dominance Chironomidae richness Mountain small stream Physical variables Biodiversity ecosystem

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Spatial and temporal patterns of forest fires in the Central Monte:relationships with regional climate

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ecological Processes 2024年第1期13卷 66-79页

作者： Pablo eugenio Villagra erica Cesca Leandro Manuel Alvarez Silvia Delgado Ricardo Villalba Instituto Argentino de Nivología Glaciología y Ciencias Ambientales–CONICeT-CCT Mendoza Facultad de Ciencias Agrarias Universidad Nacional de Cuyo

Background Natural and anthropogenic wildfires burn large areas of arid and semi-arid forests with significant socio-economic and environmental impacts. Fire regimes are controlled by climate, vegetation type, and anthropogenic factors such as ignition sources and human-induced disturbances. Projections of climate and land-use change suggest that these controlling factors will change, altering fire regimes in the near future. In the southern Central Monte, Mendoza, Argentina, the factors that modulate the fire temporal and spatial variability are poorly understood. We reconstructed the fire history of southeast of Mendoza from 1984 to 2023 and investigated the relationships between fire extent and climate variability at seasonal and interannual scales. Burned areas were determined using Google earth engine by processing Landsat 5-TM, Landsat 7-eTM+, and Landsat 8-OLI-TIRS sensor *** The region exhibited high spatial and temporal variability in fire occurrence, being a mosaic of areas with different fire histories and recovery times. Between 1985 and 2023, fire recurrence ranged from sites unburned to sites with up to 14 fires. The occurrence of large fires was strongly favored by a combination of a year with abundant spring–early summer precipitation, which favors fuel accumulation, followed by a year of low spring–early summer precipitation. Precipitation and burnt area showed a very pronounced 6–7 year cycle, suggesting a dominant climatic control on fire *** Fire distribution in southeastern Mendoza forests is not homogeneous, resulting in a mosaic of patches with different fire histories. This heterogeneity may be related to vegetation patterns and land use. The temporal variability of fires is strongly influenced by climate variability, which would promote fuel production and subsequent drying. Large fires are concentrated in periods of high interannual precipitation variability. Climate change scenarios predict an increase in tem

关键词： Fire recurrence Fire mapping Recovery time Climate Dry forest Wildfire

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evaluation of disinfection byproducts for their ability to affect mitochondrial function

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Journal of environmental Sciences 2022年第7期34卷 295-304页

作者： George William Kajjumba Rachael e.Bokota Matias Attene-Ramos erica J.Marti Department of Civil and environmental engineering University of NevadaLas VegasNVUSA Department of environmental and Occupational Health Milken Institute School of Public HealthGeorge Washington UniversityWashington DCUSA

In the race to deliver clean water to communities through potable water reuse, disinfection and water quality assessment are and will continue to be fundamental factors. There are over 700 disinfection byproducts(DBPs) in water;evaluating each compound is practically impossible and very time consuming. A bioanalytical approach could be an answer to this challenge. In this work, the response of four major classes of DBPs toward mitochondrial membrane potential( Δψm) and cytoplasmic adenosine triphosphate(C-ATP) was investigated with human carcinoma(Hep G2) cells. Within 90 min of cell exposure, only the haloacetic acid(HAA) mixture caused a cytotoxic response as measured by C-ATP. All four groups(haloacetonitriles(HANs), trihalomethanes(THMs), nitrosamines(NOAs), and HAAs) responded well to Δψm, R 2 > 0.70. Based on the half-maximum concentration that evoked a 50% response in Δψm, the response gradient was HANs >> HAAs ~ THM > NOAs. The inhibition of the Δψm by HANs is driven by dibromoacetonitrile(DBAN), while dichloroacetonitrile(DCAN) did not cause a significant change in the Δψm at less than 2000 μM. A mixture of HANs exhibited an antagonistic behavior on the Δψm compared to individual compounds. If water samples are concentrated to increase HAN concentrations, especially DBAN, then Δψm could be used as a biomonitoring tool for DBP toxicity.

关键词： Disinfection byproducts Toxicity Mitochondrial membrane potential Dose-response curve In vitro bioassay emerging contaminants

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One more chance of fistula healing in inflammatory bowel disease:Stem cell therapy

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World Journal of Clinical Cases 2018年第12期6卷 493-500页

作者： erica P Turse Francis e Dailey Maliha Naseer edward K Partyka Veysel Tahan Division of Gastroenterology and Hepatology Department of Internal MedicineUniversity of Missouri Health Center

Patients with fistulizing inflammatory bowel disease are traditionally difficult to treat. This patient population often experiences delayed or insufficient healing of fistulas using current standard regimens including anti-biotics, immunomodulators, anti-tumor necrosis factor--α drug, placement of setons, and surgical repair. Several studies over the last ten to fifteen years have been conducted using stem cell therapies with promising results in this patient population. These studies show stem cell therapy in fistulizing disease to be successful in healing between 60%--88% compared to currently 50% with infliximab. Moreover, remission was seen 24 wk to 52 wk in these studies. Further research with a multi--approach treatment using medications, stem cell therapy, and surgical interventions will likely be the future of this innovative treatment approach.

关键词： Crohn’s disease Stem cells Mesenchymal Fistulizing Fistula Inflammatory bowel disease

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Interventions to improve sarcopenia in cirrhosis: A systematic review

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World Journal of Clinical Cases 2019年第2期7卷 156-170页

作者： Maliha Naseer erica P Turse Ali Syed Francis e Dailey Mallak Zatreh Veysel Tahan Department of Internal Medicine Division of Gastroenterology and Hepatology East Carolina University Department of Internal Medicine Division of Gastroenterology St Joseph Hospital Medical Center/Creighton University Department of Internal Medicine University of Missouri Department of Internal Medicine Division of Gastroenterology and Hepatology University of Missouri

BACKGROUND Sarcopenia, i.e., muscle loss is now a well-recognized complication of cirrhosis and in cases of non-alcoholic fatty liver disease can contribute to accelerate liver fibrosis leading to cirrhosis. Hence, it is imperative to study interventions which targets to improve sarcopenia in *** To examine the relationship between interventions such nutritional supplementation, exercise, combined life style intervention, testosterone replacement and trans jugular intrahepatic portosystemic shunt(TIPS) to improve muscle mass in *** We search PubMed, eMBASe and Cochrane between June-August 2018, without a limiting period and the types of articles(RCTs, clinical trial, comparative study)in adult patients with sarcopenia and cirrhosis. The primary outcome of interest was improvement in muscle mass, strength and physical function interventions mentioned above. In the screening process, 154 full text articles were included in the review and 129 studies were *** We identified 24 studies that met review inclusion criteria. The studies were diverse in terms of the design, setting, interventions, and outcome *** performed only qualitative synthesis of evidence due to heterogeneity amongst studies. Risk of bias was medium in most of the included studies and low quality of evidence showed improvement in the muscle mass, strength and physical function following aerobic exercise. 60% of the included studies on the nutritional intervention, 100% of the studies on testosterone replacement in hypogonadal men and trans-jugular portosystemic shunt were proved to be effective in improving sarcopenia in *** Although the quality of evidence is low, the findings of our systematic review suggest improvement in the sarcopenia in cirrhosis with exercise, nutritional interventions, hormonal and TIPS interventions. High quality randomized controlled trials needed to further strengthen these findings.

关键词： Sarcopenia Cirrhosis Treatment Intervention Nutrition Therapy exercise Testosterone Trans jugular intrahepatic portosystemic shunt

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Antibiotic Resistance Profile of enterococcus faecalis and enterococcus faecium Isolates from Urine and Pleural Fluid in Two Hospitals of Cameroon

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Open Journal of Medical Microbiology 2024年第1期14卷 39-49页

作者： Cécile Ingrid Djuikoue Farid Wega Grace Yemina Kombeu Cedric Seugnou Nana Christiane Possi Kiyang Lussabella Pohoko Medzam erica Megane Noubissi Makougoum Nellie Mbianga Nkuigoua Herman Koyouo Tagne Mérimé Joël Tchinda Talokou Yvonne Valérie Yolande Mavoungou Ashu Michel Agbor Microbiology Department of the Faculty of Health Sciences of the Université des Montagnes Bangangté Cameroon Faculty of Medicine and Pharmaceutical Sciences University of Douala Douala Cameroon Microbiology Department of the Faculty of Health Sciences of Institut Universitaire du Golf de Guinée Douala Cameroon Centre Hospitalier Dominicain St Martin de Porres Yaoundé Cameroun Faculté des Sciences de la Santé Université Marien Ngouabi Brazzaville République du Congo

enterococcus faecalis and enterococcus faecium rank among the leading causes of nosocomial bacteremia and urinary tract infections. They often persist on hospital surfaces due to their ability to withstand adverse environmental conditions (low or high temperatures, high pH, and high salinity). The global enterococcus faecalis-enterococcus faecium ratio is currently shifting towards enterococcus faecium. enterococci present variable levels of resistance to certain families of antibiotics. This is the case for aminoglycosides, beta-lactams and cephalosporins. In 2017, WHO ranked enterococci among priority pathogens for research and development of new antibiotics. The objective of our study was to determine the antibiotic resistance profile of enterococcus faecalis and enterococcus faecium isolates from urine and pleural fluid in two hospitals in Cameroon. This cross-sectional and analytic study was carried out between June to August 2023 on hospitalized and day patients in which a cytobacteriological test of urine and pleural fluid was done. The samples were inoculated on CLeD Agar for urine and on Chocolate + polyvitex and blood agar (prepared from Columbia agar) for pleural fluid samples and incubated at 37℃ for 18 to 24 hours. Identification of isolates was carried out using the API 20 STReP micro gallery (Biomerieux, France) and tested for antimicrobial susceptibility. The data on socio-demographical and potential risk factors were recorded using self-administered questionnaires and data from laboratory analyses of the specimen were collected in a data capture sheet. Potential risk factors associated with the presence of enterococci, were evaluated using the logistic regression in univariate and multivariate analysis. P value ered as significant. A total of 511 patients were recruited who were predominantly females. enterococcus spp were isolated in 27.79% of our samples with enterococcus faecalis mostly encountered. enterococcus spp showed a high

关键词： enterococcus faecalis enterococcus faecium Healthcare-Associated Infections Antimicrobial Resistance Cameroon

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Key Factors Involved in Lamb Quality from Farm to Fork in europe

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Journal of Integrative Agriculture 2013年第11期12卷 1919-1930页

作者： Carlos Saudo erica Muela María del Mar Campo Department of Animal Production and Food Science University of Zaragoza

World lamb consumption is approximately 2 kg per capita with large variations between continents, e.g., 17 kg in Oceania vs. 0.7 kg in North America. With less than one million tonnes, the international trade of sheep meat contributes to a small percentage of the total meat exchanged between countries. On the other hand, lamb represents the highest rate of species trading in relation to the total sheep meat produced. It is therefore likely to ifnd a wide variability of different lamb products in the same market, and that the conservation procedures （such as refrigeration, packaging or freezing）, chemical composition, especially the fat due to its implication in human health, lfavour development and juiciness perception （affected, i.e., by the feeding or the age or slaughter weight of the animal） and acceptability （based on culinary background） could be considered important indicators of this advantageous situation. In this paper some studies related to the aforementioned indicators are discussed.

关键词： technology chemical composition consumer preferences

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Natural enemies depend on remnant habitat size in agricultural landscapes

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Journal of Forestry Research 2015年第2期26卷 469-477页

作者： Mainara Xavier Jordani erica Hasui Vinicius Xavier da Silva Laboratorio de ecologia Animal Departamento de Zoologia e BotanicaUniversidade Estadual Paulista-UNESPRua Cristovao Colombo2265Jardim NazarethSao Jose Do Rio PretoSP CEP 15054-000Brazil Laboratorio de ecologia de Fragmentos do Sul de Minas Gerais-eCOFRAG Instituto Ciencias da NaturezaUniversidade Federal de Alfenas-UNIFAL–MGRua Gabriel Monteiro da Silva700CentroAlfenasMG CEP 37130-000Brazil

In recent decades,the consequences of habitat fragmentation have been of growing concern,because it is particularly important to understand how fragmentation may affect biodiversity,an ecological *** tested two hypotheses：（1） that natural fragment size in agricultural landscapes indirectly affects the herbivore through effects on natural predator populations;and（2） predator activity into the crop reduces along the distance from the natural fragment *** 2008 and 2009,we conducted our study in seven forest remnants and in surrounding coffee plantations（fragments ranged from 6 to 105 ha,mean 49.28 ± 36.60 ha） in Southern Minas Gerais,*** were sampled by point counts,and insect predation was evaluated by using an artificial insect model（Koh and Menge 2006）.Our results suggest that although there were many potential predators（e.g.,wasps,ants,birds,and mammals）,birds were the most important taxon *** covariance analysis supported the hypothesis that patch size affected the number of larvae predation by overall taxi,but there was no support for a distance *** findings suggest that natural enemies’ ecological service（mainly from birds） declined with remnant reduction,which has implications not only for human welfare,but also in strengthening the economic justifications for conserving the remaining natural habitats and biodiversity in agricultural landscapes.

关键词： ecosystem service Fragmentation Isolation Insectivore Predation

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A review of post-incident studies for wildland-urban interface fires

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Journal of Safety Science and Resilience 2020年第1期1卷 59-65页

作者： Benjamin Gaudet Albert Simeoni Steven Gwynne erica Kuligowski Noureddine Benichou Worcester Polytechnic Institute WorcesterMAUnited States Movement Strategies LondonUnited Kingdom National Institute of Standards and Technology GaithersburgMDUnited States National Research Council Canada OttawaOntarioCanada

Post-incident studies provide direct and valuable information to further the scientific understanding of Wildland-Urban Interface(WUI)*** post-incident studies involve data collection in the field(i.e.a“research field deployment”).In this review,technical reports of post-incident studies for WUI fire and other natural disasters were analyzed and professionals directly involved in WUI fire research field deployments were *** goal of this review is to provide a resource for future WUI studies regarding the development of safe and effective fieldwork procedures,the collection and integration of accurate and relevant data,and the establishment of practical lessons *** main stages of WUI fire post-incident studies are identified and described in *** collection methodologies,data attributes,logistical practices and lessons-learned were compiled from various past studies and are presented here in the context of application to WUI fire.

关键词： Wildland-urban interface fire WUI fire Post-incident study Natural disaster study

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CD137 agonist potentiates the abscopal efficacy of nanoparticle-based photothermal therapy for melanoma

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Nano Research 2022年第3期15卷 2300-2314页

作者： Preethi Bala Balakrishnan Debbie KLedezma Juliana Cano-Mejia Jaclyn Andricovich erica Palmer Vishal APatel Patricia SLatham eric SYvon Alejandro Villagra Rohan Fernandes elizabeth e.Sweeney GW Cancer Center Department of MedicineSchool of Medicine and Health SciencesGeorge Washington UniversityWashingtonDC 20052USA The Institute for Biomedical Sciences School of Medicine and Health SciencesGeorge Washington UniversityWashingtonDC 20052USA GW Cancer Center Department of Biochemistry and Molecular MedicineSchool of Medicine and Health SciencesGeorge Washington UniversityWashingtonDC 20052USA Department of Dermatology&Oncology School of Medicine and Health SciencesGeorge Washington UniversityWashingtonDC 20037USA Department of Pathology School of Medicine and Health SciencesGeorge Washington UniversityWashingtonDC 20037USA ImmunoBlue BethesdaMD 20817USA

Despite the promise of immunotherapy such as the immune checkpoint inhibitors(ICIs)anti-PD-1 and anti-CTLA-4 for advanced melanoma,only 26%–52%of patients respond,and many experience grade III/IV immune-related adverse *** by the need for an effective therapy for patients non-responsive to clinically approved ICIs,we have developed a novel nanoimmunotherapy that combines locally administered Prussian blue nanoparticle-based photothermal therapy(PBNP-PTT)with systemically administered agonistic anti-CD137 monoclonal antibody therapy(aCD137).PBNP-PTT was administered at various thermal doses to melanoma cells in vitro,and was combined with aCD137 in vivo to test treatment effects on melanoma tumor progression,animal survival,immunological protection against tumor rechallenge,and *** administered at a melanoma-specific thermal dose,PBNP-PTT elicits immunogenic cell death(ICD)in melanoma cells and upregulates markers associated with antigen presentation and immune cell co-stimulation in ***,PBNP-PTT eliminates primary melanoma tumors in vivo,yielding long-term tumor-free ***,the antitumor immune effects generated by PBNP-PTT cannot eliminate secondary tumors,despite significantly slowing their *** addition of aCD137 enables significant abscopal efficacy and improvement of survival,functioning through activated dendritic cells and tumor-infiltrating CD8^(+)T cells,and generates CD4^(+)and CD8^(+)T cell memory that manifests in the rejection of tumor rechallenge,with no long-term *** study describes for the first time a novel and effective nanoimmunotherapy combination of PBNP-PTT with aCD137 mAb therapy for melanoma.

关键词： photothermal therapy Prussian blue nanoparticles anti-CD137 melanoma nanoimmunotherapy

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