检索结果-南通市图书馆

在线全文

学校读者我要写书评

暂无评论

在新发展公司中投资的考核表

经济译文 1990年第4期 39-43页

作者：斯旺.,sc 王忠郴

脑血管病长期存活者心电图异常、高血压病对照研究

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中华神经精神科杂志 1989年第2期22卷 104-107页

作者：王可嘉 Bruce S sc 湖北医科大学附一院神经科美国国立卫生研究院神经病

本文报告78例脑血管病的病例对照研究的结果：心电图异常仅与女性患者有关（P＜0．05）；急性期神智丧失与后来心电图异常及严重神经功能障碍有关（P＜0．05）；高血压对脑血管病长期存活者仍是一种危险因素（P＜0．01）；65岁以上比65... 详细信息

本文报告78例脑血管病的病例对照研究的结果：心电图异常仅与女性患者有关（P＜0．05）；急性期神智丧失与后来心电图异常及严重神经功能障碍有关（P＜0．05）；高血压对脑血管病长期存活者仍是一种危险因素（P＜0．01）；65岁以上比65岁以下患者有高血压的更多（P＜0．05）。

关键词：高血压脑血管病心电图病例对照研究

在线全文

学校读者我要写书评

暂无评论

大型零件的高效涂层工艺-粉末填充埋弧焊

中国表面工程 2009年第5期22卷 13-15,19页

作者： sc. Hans Hallen Karl-Erik Johansson Hoganas AB 263 83 HoganasSweden 赫格纳斯(中国)有限公司上海201700

描述了一种对连铸辊轮表面双层熔覆的埋弧焊新工艺。它采用了两根低合金电极(Φ2.5 mm)和一种高合金填充粉末。这种工艺效率高,得到的组织细且均匀,并且根据不同要求可以灵活改变涂层成份。

关键词：连铸辊轮埋弧焊 SWP^TM 表面熔覆金属粉末原子吸收法

Quetiapine augmentation of prolonged exposure therapy in veterans with PTSD and a history of mild traumatic brain injury: design and methodology of a pilot study

在线全文

学校读者我要写书评

暂无评论

Military Medical Research 2021年第1期8卷 121-131页

作者： Muhammad R.Baig Robert D.Beck Jennifer L.Wilson Jennifer A.Lemmer Adeel Meraj Eric C.Meyer jim Mintz Alan L.Peterson John D.Roache Mental Health South Texas Veterans Healthcare System116 A7400 Merton Minter BIvdSan AntonioTX 78229USA Polytrauma Rehabilitation Center South Texas Veterans Healthcare SystemSan AntonioTXUSA Department of Psychiatry and Behavioral sciences University of Texas Health Science Center at San AntonioSan AntonioTXUSA Department of Veterans Affairs VISN 17 Center of Excellence for Research on Returning War Veterans WacoTXUSA Central Texas Veterans Healthcare System WacoTXUSA Department of Psychology and Neuroscience Baylor UniversityWacoTXUSA Department of Epidemiology and Biostatistics University of Texas Health Science Center at San AntonioSan AntonioTXUSA Department of Psychology University of Texas at San AntonioSan AntonioUSA Department of Pharmacology University of Texas Health Science Center at San AntonioSan AntonioTXUSA

Background: Selective serotonergic reuptake inhibitors(SSRIs) are first-line pharmacologic treatments for patients with posttraumatic stress disorder(PTSD), but must be given over extended period of time before the onset of action. The use of SSRIs in PTSD patients with mild traumatic brain injury(m TBI) is problematic since SSRIs could exacerbate post-concussion syndrome(PCS) symptoms. VA/DOD guidelines identify trauma-focused psychotherapy as the best evidence-based treatment for PTSD, but overall effectiveness is limited by reduced levels of patient engagement and retention. A previous study from this research group suggested that quetiapine monotherapy, but not risperidone or valproate, could increase engagement in trauma-focused ***: We report the study protocol of a pilot study funded under the South-Central Mental Illness Research, Education, and Clinical Center pilot study program from the U.S. Department of Veterans Affairs. This randomized, open-label study was designed to evaluate the feasibility of completing a randomized trial of quetiapine vs. treatment as usual to promote patient engagement in PTSD patients with a history of m ***: We expect that the success of this ongoing study should provide us with the preliminary data necessary to design a full-scale randomized trial. Positive efficacy results in a full-scale trial should inform new VA guidelines for clinical practice by showing that quetiapine-related improvements in patient engagement and retention may be the most effective approach to assure that VA resources achieve the best possible outcome for *** registration: NCT04280965.

关键词： Quetiapine Trauma-focused psychotherapy Posttraumatic stress disorder Mild traumatic brain injury Veterans

A Comparative Study of the Cytotoxicity of Silver-based Dressings in Monolayer Cell,Tissue Explant,and Animal Models

在线全文

学校读者我要写书评

暂无评论

A Comparative Study of the Cytotoxicity of Silver-based Dres...

第八届全国烧伤外科学年会

作者： Burd A Kwok CH Hung sc Lam WK Division of Plastic and Reconstructive Surgery Department of SurgeryThe Chinese University of Hong KongPrince of Wales HospitalHong Kong

＜正＞Over the past decade,a variety of advanced silver-based dressings have been *** are considerable variations in the structure,composition,and silver content of these new *** the present study,we examined five commercially available silver-based dressings （Acticoat,Aquacel Ag, Contreet Foam,PolyMem Silver,Urgotul SSD）.We assessed their cytotoxicity in a monolayer cell culture, a tissue explant culture model,and a mouse excisional wound *** results showed that Acticoat, Aquacel Ag,and Contreet Foam,when pretreated with specific solutes,were likely to produce the most significant cytotoxic effects on both cultured keratinocytes and fibroblasts,while PolyMem Silver and Urgotul SSD demonstrated the least *** cytotoxicity correlated with the silver released from the dressings as measured by silver concentration in the culture *** the tissue explant culture model,in which the epidermal cell proliferation was evaluated,all silver dressings resulted in a significant delay of *** the mouse excisional wound model,Acticoat and Contreet Foam indicated a strong inhibition of wound reepithelialization on the postwounding-day *** findings may,in part, explain the clinical observations of delayed wound healing or inhibition of wound epithelialization after the use of certain topical silver *** should be exercised in using silver-based dressings in clean superficial wounds such as donor sites and superficial burns and also when cultured cells are being applied to wounds.

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

蠕虫对宿主体内最适寄生部位的选择

国外医学（寄生虫病分册） 1995年第4期22卷 149-152页

作者： Sukhdeo MVK Sukhdeo sc 潘劲草

脊椎动物的寄生蠕虫通常在宿主体内选择非常特异的寄生部位,且此前往往需经过宿主多个器官的移行过程。然而,其机制至今未明。本文提出一种研究蠕虫此种行为的思路,即从寄生虫自身的角度及其对环境察识的观点出发来考虑,寄生虫的环境特... 详细信息

脊椎动物的寄生蠕虫通常在宿主体内选择非常特异的寄生部位,且此前往往需经过宿主多个器官的移行过程。然而,其机制至今未明。本文提出一种研究蠕虫此种行为的思路,即从寄生虫自身的角度及其对环境察识的观点出发来考虑,寄生虫的环境特征及其对环境的应答活动构成了行为的基本因素。结果提示,蠕虫对宿主体内固定环境的应答通常是以定型的方式进行,假设宿主体内生理与生化的平衡给寄生虫提供了一可预测的环境,寄生虫只需感知环境信息中的少量信息即可诱发合宜的应答。然而对寄生虫的感觉及神经系统的研究存在技术困难,因此,须考虑应用多学科方法(寄生虫学、生态学、进化生物学和神经行为学等)来研究寄生虫的行为策略,预期未来的研究方向应是寄生虫感觉生理学和行为生态学的综合。

关键词：蠕虫宿主体内寄生部位

Analytical Approach for Forecasting of Measurement Value from Dam Monitoring

在线全文

学校读者我要写书评

暂无评论

Analytical Approach for Forecasting of Measurement Value fro...

The modulation of co-stimulatory molecules by circulating exosomes in primary biliary cirrhosis

第一届堆石坝国际研讨会

作者： Slavko Milevski M.sc.Civ.Eng Macedonian Power Plant Department for technical monitoring and maintenance at dams and other civil objectsPlostad na revolucija b.b.6330 Struga R.Macedonia

＜正＞Analysis of Data’s from Dam Monitoring is very important factor for dam behavior. Monitoring of various quantities is performed within the technical monitoring system of dam,with aim to provide an assessment of dam behavior. Monitored values should be within in certain range depending on dam type,quantity type,as well as on the changing range of external physical causing quantities. Last years are increased acknowledgements in direction of discovery analytical methods which uses data’s from dam monitoring to get better result in forecast of dam’s behavior. In Employment for technical monitoring at dams was developed model for forecasting of measurement value from dam monitoring. Model uses method of multiple statistical correlations for forecasting of measurement value on measurement place（instrument）.Calculated theoretical value can be compare with measured *** when measurement values outdo expected theoretical value,control would be initializing. Model is base at assumption that measurement value can be function from time,hydrostatical effect and influence of season. With calculation of equation for each measurement data are gain system of equation and solving of this system of equation is gain prognoses value. For practical use of model is made an application in Visual *** use measurement data’s stored in databases. In this paper will be described implementation of that model for monitoring data’s assessment from dam in frame of Company Macedonian power plants. This model uses existing monitoring database’s,across the user-friendly interface.

关键词： dam monitoring data measurement model

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2017年第3期14卷 276-284页

作者： Takashi Tomiyama Guo-Xiang Yang Ming Zhao Weici Zhang Hajime Tanaka Jing Wang Patrick sc Leung Kazuiclli Okazaki Xiao-Song He Qianjin Lu Ross L Coppel Christopher L Bowlus M Eric Gershwin Division of Rheumatology Allergy and Clinical Immunology University of California at Davis Davis CA 95616 USA Third Department of Internal Medicine Division of Gastroenterology and Hepatology Kansai Medical University Osaka 573-1191 Japan Hunan Key Laboratory of Medical Epigenomics Department of Dermatology The Second Xiangya Hospital Central South University Changsha Hunan 410011 People's Republic of China Department of Gastroenterology and Metabolism Nagoya City University Graduate School of Medical Sciences Nagoya 467-8601 Japan Department of Microbiology Monash University Melbourne Australia Division of Gastroenterology and Hepatology University of California at Davis School of Medicine. Sacramento. CA 95817. USA

Exosomes are nanoparticles of endocytic origin, secreted by a myriad of cell populations that are attracting increased attention by virtue of their ability to modulate cell-to-cell communications. They are also attracting attention in a variety of immunological issues, including autoimmunity and, in particular, their ability to regulate cytokine and chemokine activation. Primary biliary cirrhosis （PBC） is considered a model autoimmune disease, which has a highly focused cytotoxic response against biliary epithelial cells. We have isolated exosomes from plasma from 29 patients with PBC and 30 healthy controls （HCs）, and studied the effect of these exosomes on co-stimulatory molecule expression and cytokine production in mononuclear cell populations using an ex vivo system. We also identified the microRNA （miRNA） populations in PBC compared to HC exosomes. We report herein that although exosomes do not change cytokine production, they do significantly alter co-stimulatory molecule expression on antigen-presenting populations. Further, we demonstrated that CD86 up-regulated expression on CD14＋ monocytes, whereas CD40 up-regulated on CD11c＋ dendritic cells by exosomes from patients with PBC. In addition, there were differences of miRNA expression of circulating exosomes in patients with PBC. These data have significant importance based on observations that co-stimulatory molecules play a differential role in the regulation of T-cell activation. Our observation indicated that aberrant exosomes from PBC selectively induce expression of co-stimulatory molecules in different subset of antigen-presenting cells. These alterations may involve in pathogenesis of autoimmune liver disease.

关键词： autoimmunity exosome microRNA primary biliary cirrhosis

根治术后病理T3期或切缘阳性前列腺癌的辅助放疗的系统综述和荟萃分析

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国癌症杂志 2009年第2期19卷 83-84页

作者： Morgan sc Waldron TS Eapen L 秦晓健单位不详

研究背景：前列腺癌是西方国家男性最常见的非皮肤来源恶性肿瘤,病死率排第二位。根治性前列腺切除（RP）是临床局限性前列腺癌标准的外科治疗手段。然而,术后病理诊断发现肿瘤侵出前列腺包膜（pT3）或者切缘阳性（R1）的患者预后不佳,... 详细信息

研究背景：前列腺癌是西方国家男性最常见的非皮肤来源恶性肿瘤,病死率排第二位。根治性前列腺切除（RP）是临床局限性前列腺癌标准的外科治疗手段。然而,术后病理诊断发现肿瘤侵出前列腺包膜（pT3）或者切缘阳性（R1）的患者预后不佳,5年生化疾病进展率高达67%。目前接受RP手术的患者中约有50％会碰到以上至少一种情况。

关键词：局限性前列腺癌术后病理诊断切缘阳性根治性荟萃分析系统综述辅助放疗 T3期