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Tribological behaviour of fused deposition modelling printed short carbon fibre reinforced nylon composites with surface textures under dry and water lubricated conditions

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Friction 2022年第12期10卷 2045-2058页

作者： Ming LUO Siyu HUANG Ziyan MAN julie M.CAIRNEY Li CHANG school of Aerospace Mechanical and Mechatronic EngineeringThe University of SydneySydney NSW 2006Australia Australian Centre for Microscopy and Microanalysis The University of SydneySydney NSW 2006Australia

Fused deposition modelling(FDM)printed short carbon fibre reinforced nylon(scFRN)composites were *** friction and wear behaviour of printed materials were systematically investigated under both dry sliding and water lubricated *** results showed that with short fibre enhancements,the printed scFRN achieved a lower friction coefficient and higher wear resistance than nylon under all tested ***,under water lubricated conditions,the printed scFRN exhibited a low,stable friction coefficient due to the cooling and lubricating effects of ***,the specific wear rate of the printed specimens could be higher than that obtained under dry sliding conditions,especially when the load was relatively *** square textured surface was designed and created in the printing process to improve materials’tribological *** was found that with the textured surface,the wear resistance of the printed scFRN was improved under dry sliding conditions,which could be explained by the debris collection or cleaning effect of surface ***,such a cleaning effect was less noticeable under lubricated conditions,as the liquid could clean the surface *** the other hand,surface textures could increase the surface area exposed to water,causing surface softening due to the higher water absorption *** a result,the samples having surface textures showed higher wear rates under lubricated *** work has provided new insights into designing wear resistant polymer materials using three-dimensional(3D)printing technologies,subjected to different sliding conditions.

关键词： fused deposition modelling(FDM) short carbon fibre reinforced nylon(scFRN)composites transfer film friction and wear

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Enzymatic Synthesis of Polycaprolactone:Effect of Immobilization Mechanism of CALB on Polycaprolactone Synthesis

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Journal of Renewable Materials 2018年第6期6卷 619-629页

作者： Yasemin Kaptan.M.sc Yüksel Avcıbaşı-Güvenilir Istanbul Technical University Department of Chemical EngineeringIstanbul Technical University34469Maslak-Istanbul

Surface-modified rice husk ash was used as an inorganic support material for immobilization of Candida antarctica lipase B.(3-aminopropyl)trimethoxysilane was used for surface *** of CALB was performed via both physical adsorption and *** synthesis was carried out by using these immobilized enzymes,free enzyme and Novozyme 435®.Molecular weight distribution of polymer samples was obtained by gel permeation chromatography(GPC)and chain structures of the polymer samples were observed by hydrogen nuclear magnetic resonance(1H-NMR).The highest monomer conversion is generally obtained by using cross-linked enzyme,around 90%.PDI values for all polymer samples were approximately 1.5 which can be considered as *** general cross-linked enzymes were better than physically adsorbed enzymes in terms of average molecular *** can be concluded that PCL can be synthesized with these immobilized enzymes with high molecular weight and low PDI values.

关键词： Candida antarctica lipase B cross-linking physical adsorption Polycaprolactone rice husk ash

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Epigenetic mechanisms of liver tumor resistance to immunotherapy

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World Journal of Hepatology 2021年第9期13卷 979-1002页

作者： julie Sanceau Angelique Gougelet Centre de Recherche des Cordeliers Sorbonne UniversiteInsermUniversite de ParisParis 75006France

Hepatocellular carcinoma(HCC)is the most common primary liver tumor,which stands fourth in rank of cancer-related deaths *** incidence of HCC is constantly increasing in correlation with the epidemic in diabetes and obesity,arguing for an urgent need for new treatments for this lethal cancer refractory to conventional *** is the paradigm of inflammation-associated cancer,since more than 80% of HCC emerge consecutively to cirrhosis associated with a vast remodeling of liver *** the recent decade,immunomodulatory drugs have been developed and have given impressive results in melanoma and later in several other *** the present review,we will discuss the recent advancements concerning the use of immunotherapies in HCC,in particular those targeting immune checkpoints,used alone or in combination with other anticancers *** will address why these drugs demonstrate unsatisfactory results in a high proportion of liver cancers and the mechanisms of resistance developed by HCC to evade immune response with a focus on the epigeneticrelated mechanisms.

关键词： Liver cancer Immunotherapies Epigenetics Resistance Hepatocellular carcinoma

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Two Novel Sesquiterpene Diglycosides from Dictamnus dasycarpus

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Chinese Chemical Letters 1999年第7期10卷 563-566页

作者： Zhao, WM Wang, sc Hostettmann, K Qin, GW Xu, RS Chinese Acad sci Shanghai Inst Mat Med Shanghai 200031 Peoples R China Univ Lausanne Coll Pharm CH-1015 Lausanne Switzerland

Two novel sesquiterpene diglycosides named dictamnosides F 1 and G 2 were isolated from methanol extract of the root bark of Dictamnus dasycarpus. Their structures were determined on the basis of spectroscopic and che... 详细信息

关键词： Dictamnus dasycarpus Rutaceae dictamnosides F and G sesquiterpene diglycosides

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Morphological structure and optical properties of the wings of Morphidae

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Insect science 2006年第2期13卷 145-158页

作者： SERGE BERTHIER ERIC CHARRON julie BOULENGUEZ Institut des Nanosciences de Pads UMR CNRS-Universite Pierre et Made Curie Pads France

The morphological structure and optical properties of the wings of 14 species of Morphidae have been investigated. Most of the scales of the iridescent species of Morphidae （Lepidoptera） present a very particular structure. The ground scales, responsible for the major part of the optical properties, are covered by a very regular set of longitudinal ridges. The ridges themselves are constituted by a superposition of lamellae that act locally as a multilayered structure. This very specific morphology leads to both interferences and diffraction effects. The first one is responsible of the brilliant blue coloration of the males, while the second one diffracts this colored light at a very large angle. These two phenomena give to the butterfly a very effective long-range communication system. The morphological characteristics of the scales of the various species are presented in detail. Two types of optical measurement were performed on the iridescent wings of 14 different species of Morphidae： spectroscopic measurements under various incidences and gonioscopic measurements for a given incidence angle and wavelength. The first allows a determination of the index of refraction of the cuticular material. The second leads to the drawing of spatial diffraction maps. It shows that most of the reflected light is diffracted laterally over a very large angle （90° 〈 0 〈 120°, according to the different species） and that this repartition depends of the polarization of incident light. As predicted by previous calculations, the dissymmetric structure of the ridge is responsible for the separation of the polarization modes in the various diffraction orders.

关键词： Iridescence morphidae optical properties photonic cristals physical colors,scales structures

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Central role of the LEAFY COTYLEDON1 transcription factor in seed development

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Journal of Integrative Plant Biology 2019年第5期61卷 564-580页

作者： Leonardo Jo julie M.Pelletier John J.Harada Department of Plant Biology and Plant Biology Graduate Group University of CaliforniaDavis USA

Seed development is a complex period of the flowering plant life *** fertilization,the three main regions of the seed,embryo,endosperm and seed coat,undergo a series of developmental processes that result in the production of a mature seed that is developmentally arrested,desiccated,and metabolically *** processes are highly coordinated,both temporally and spatially,to ensure the proper growth and development of the *** transcription factor,LEAFY COTYLEDON1(LEC1),is a central regulator that controls several aspects of embryo and endosperm development,including embryo morphogenesis,photosynthesis,and storage reserve ***,LEC1 regulates distinct sets of genes at different stages of seed *** its critical importance for seed development,an understanding of the mechanisms underlying LECi's multifunctionality is only beginning to be *** studies describe the roles of specific transcription factors and the hormones,gibberellic acid and abscisic acid,in controlling the activity and transcriptional specificity of LEC1 across seed ***,studies indicate that LEC1 acts as a pioneer transcript!on factor to promote epigenetic reprogramming during *** this review,we discuss the mechanisms that enable LEC1 to serve as a central regulator of seed development.

关键词： Seed development flowering plant seed development

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Monotonic Diamond and DDFV Type Finite-Volume schemes for 2D Elliptic Problems

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Communications in Computational Physics 2023年第7期34卷 456-502页

作者： Xavier Blanc Francois Hermeline Emmanuel Labourasse julie Patela UniversitéParis Cité Sorbonne UniversitéCNRSLaboratoire Jacques-Louis LionsF-75013 ParisFrance CEA DAMDIFF-91297 ArpajonFrance UniversitéParis-Saclay CEA DAM DIFLaboratoire en Informatique Haute Performance pour le Calcul et la Simulation91297 ArpajonFrance

The DDFV(Discrete Duality Finite Volume)method is a finite volume scheme mainly dedicated to diffusion problems,with some outstanding *** scheme has been found to be one of the most accurate finite volume methods for diffusion *** the present paper,we propose a new monotonic extension of DDFV,which can handle discontinuous tensorial diffusion ***,we compare its performance to a diamond type method with an original interpolation method relying on polynomial *** is achieved by adapting the method of Gao et al[A finite volume element scheme with a monotonicity correction for anisotropic diffusion problems on general quadrilateral meshes]to our *** a technique does not require the positiveness of the secondary *** show that the two new methods are second-order accurate and are indeed monotonic on some challenging benchmarks as a Fokker-Planck problem.

关键词： Finite volume method anisotropic diffusion monotonic method DDFV scheme

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Sharing Results with Clinical Trial Participants： Insights from an Online Survey of Chinese Consumers

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Chinese Medical Journal 2016年第8期129卷 1007-1008页

作者： Janelle R Keys julie A Monk Karen L Woolley Proscribe-Envision Pharma Group Sydney NSW 2113 Australia Faculty of science Health Education and Engineering University of the Sunshine Coast Maroochydore DC Queensland Australia Faculty of Health and Behavioural sciences University of Queensland Brisbane Queensland Australia

To the Editor：Clinical trial participants have a right to know the results from the trials that they enable. European and North American research,however,shows that trial results are rarely shared with participants. Given the increase in industry-sponsored trials in China,we conducted the first investigation into Chinese consumer views about sharing the clinical trial results with participants.

关键词： Sharing Results Clinical Trial Participants Chinese Consumers

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Fungi and insects as models of extraordinary symbiosis

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Studies in Fungi 2021年第1期6卷 469-479页

作者： Elkhateeb W Karunarathna sc Daba GM Chemistry of Natural and Microbial Products Department Pharmaceutical Industries DivisionNational Research CentreDokkiGiza12622Egypt Centre for Mountain Futures(CMF) Kunming Institute of BotanyChinese Academy of SciencesKunmingChina

Symbiosis among microorganisms represents an interesting relationship that takes different ***,facultative,and endosymbiotic relationships have all been reported between different *** it is mutualism,commensalism,amensalism,or parasitism,understanding every association is of great importance to science and *** how these creatures benefit from each other may be useful for biocontrol purposes,or even for discovery of novel metabolites that result from these associations,and which may not be produced by the individual *** this review,five examples of symbiosis were presented,including among the Laboulbeniales;Septobasidium;Ambrosia Fungi and Beetles;Leaf-cutter ants and their fungus gardens;and finally,termites and ***,the benefits each partner is getting were highlighted,and uniqueness in every form of those symbiosis models was simply described.

关键词： Ambrosia Fungi Beetles Fungus garden Laboulbeniales Leaf cutter ants Septobasidium Symbiosis

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Hypoxia-ischemia in the immature rodent brain impairs serotonergic neuronal function in certain dorsal raphé nuclei

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Neural Regeneration Research 2020年第3期15卷 457-463页

作者： Hanna E.Reinebrant julie A.Wixey Kathryn M.Buller UQ Centre for Clinical Research Faculty of Medicine The University of Queensland

Neonatal hypoxia-ischemia(HI) results in losses of serotonergic neurons in specific dorsal raphé nuclei. However, not all serotonergic raphé neurons are lost and it is therefore important to assess the function of remaining neurons in order to understand their potential to contribute to neurological disorders in the HI-affected neonate. The main objective of this study was to determine how serotonergic neurons, remaining in the dorsal raphé nuclei after neonatal HI, respond to an external stimulus(restraint stress). On postnatal day 3(P3), male rat pups were randomly allocated to one of the following groups:(i) control + no restraint(n = 5),(ii) control + restraint(n = 6),(iii) P3 HI + no restraint(n = 5) or(iv) P3 HI + restraint(n = 7). In the two HI groups, rat pups underwent surgery to ligate the common carotid artery and were then exposed to 6% O2 for 30 minutes. Six weeks after P3 HI, on P45, rats were subjected to restraint stress for 30 minutes. Using dual immunolabeling for Fos protein, a marker for neuronal activity, and serotonin(5-hydroxytrypamine; 5-HT), numbers of Fos-positive 5-HT neurons were determined in five dorsal raphé nuclei. We found that restraint stress alone increased numbers of Fos-positive 5-HT neurons in all five dorsal raphé nuclei compared to control animals. However, following P3 HI, the number of stress-induced Fos-positive 5-HT neurons was decreased significantly in the dorsal raphé ventrolateral, interfascicular and ventral nuclei compared with control animals exposed to restraint stress. In contrast, numbers of stress-induced Fos-positive 5-HT neurons in the dorsal raphé dorsal and caudal nuclei were not affected by P3 HI. These data indicate that not only are dorsal raphé serotonergic neurons lost after neonatal HI, but also remaining dorsal raphé serotonergic neurons have reduced differential functional viability in response to an external stimulus. Procedures were approved by the University of Queensland Animal Ethics Committee(

关键词： dorsal raphé nuclei Fos hypoxia-ischemia neonate newborn brain injury preterm restraint stress serotonin

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